Page last updated: 2024-10-28

lidocaine and Nervous System Disorders

lidocaine has been researched along with Nervous System Disorders in 44 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"In this population of patients referred for elective cardioversion of atrial fibrillation, high-dose bolus lidocaine was ineffective in converting patients to sinus rhythm."9.09High-dose bolus lidocaine for chemical cardioversion of atrial fibrillation: a prospective, randomized, double-blind crossover trial. ( Bardy, GH; Marrouche, NF; Reddy, RK; Wittkowsky, AK, 2000)
"Lidocaine has been used in treatment of patients with refractory headache."8.85Neuropsychiatric side-effects of lidocaine: examples from the treatment of headache and a review. ( Gil-Gouveia, R; Goadsby, PJ, 2009)
"Chronic neurogenic facial pain is commonly resistant to treatment and is often the source of significant patient morbidity."6.69Chronic neurogenic facial pain: lack of response to intravenous phentolamine. ( Chaudry, A; Keith, DA; Maciewicz, RJ; Scrivani, SJ, 1999)
"In 10 cancer patients with cutaneous allodynia, intravenous lidocaine (5 mg/kg body weight) or 0."6.66Trial of intravenous lidocaine on painful neuropathy in cancer patients. ( Banning, AM; Ellemann, K; Geertsen, P; Jensen, TS; Sjögren, P; Smith, T, 1989)
"Both lidocaine an adrenaline at the scheduled doses showed low sensitivity and specificity as a simulated iv epidural test dose."5.20[Epidural anaesthesia: Simulated intravascular test dose with S(+) ketamine, lidocaine and adrenaline. A prospective, randomized, double blind and placebo controlled study]. ( Errando, CL; Higueras, R; Soriano-Bru, JL, 2015)
"In this population of patients referred for elective cardioversion of atrial fibrillation, high-dose bolus lidocaine was ineffective in converting patients to sinus rhythm."5.09High-dose bolus lidocaine for chemical cardioversion of atrial fibrillation: a prospective, randomized, double-blind crossover trial. ( Bardy, GH; Marrouche, NF; Reddy, RK; Wittkowsky, AK, 2000)
"Lidocaine has been used in treatment of patients with refractory headache."4.85Neuropsychiatric side-effects of lidocaine: examples from the treatment of headache and a review. ( Gil-Gouveia, R; Goadsby, PJ, 2009)
"Lidocaine and oral analogs were safe drugs in controlled clinical trials for neuropathic pain, were better than placebo, and were as effective as other analgesics."4.82Systemic administration of local anesthetic agents to relieve neuropathic pain. ( Carr, DB; Challapalli, V; Lau, J; McNicol, ED; Tremont-Lukats, IW, 2005)
"Forty consecutive patients with neurological disorders (encephalopathy, autism, and epilepsy) were referred to dental treatment, and 45 sedations were performed; all were sedated with Midazolam (intramuscular 0."3.76Special care dentistry: Midazolam conscious sedation for patients with neurological diseases. ( Capp, PL; Cillo, MT; de Faria, ME; de Siqueira, JT; Prado, EG; Siqueira, SR, 2010)
"Prilocaine is an amide local anesthetic with a duration of action similar to that of lidocaine."2.69Transient neurologic symptoms after spinal anesthesia: a lower incidence with prilocaine and bupivacaine than with lidocaine. ( Drasner, K; Hampl, KF; Harms, C; Heinzmann-Wiedmer, S; Luginbuehl, I; Schneider, MC; Seeberger, M, 1998)
"Mepivacaine seems to be a promising alternative to lidocaine for outpatient surgical procedures because of its similar duration of action."2.69Transient neurologic symptoms after spinal anesthesia with mepivacaine and lidocaine. ( Chisholm, MF; Liguori, GA; Zayas, VM, 1998)
"Chronic neurogenic facial pain is commonly resistant to treatment and is often the source of significant patient morbidity."2.69Chronic neurogenic facial pain: lack of response to intravenous phentolamine. ( Chaudry, A; Keith, DA; Maciewicz, RJ; Scrivani, SJ, 1999)
"In 10 cancer patients with cutaneous allodynia, intravenous lidocaine (5 mg/kg body weight) or 0."2.66Trial of intravenous lidocaine on painful neuropathy in cancer patients. ( Banning, AM; Ellemann, K; Geertsen, P; Jensen, TS; Sjögren, P; Smith, T, 1989)
"Lidocaine has been used for spinal anesthesia since 1948, seemingly without causing concern."2.43Transient neurologic symptoms after spinal anesthesia with lidocaine versus other local anesthetics: a systematic review of randomized, controlled trials. ( Christiansen, C; Pace, NL; Punjasawadwong, Y; Zaric, D, 2005)
"Neuropathic pain has long been recognised as one of the more difficult types of pain to treat; however, with the current emphasis on providing a multidisciplinary assessment and approach to management, more patients will be offered relief of their symptoms and an improved quality of life."2.41Management strategies for the treatment of neuropathic pain in the elderly. ( Ahmad, M; Goucke, CR, 2002)
"Neuropathic pain is challenging to treat, partly because of the systemic side effects of the commonly used medications."1.35[What is the place of topical analgesia in neuropathic pain?]. ( Besson, M; Desmeules, J; Piguet, V, 2008)
"Thrombocytopenia is considered a relative contraindication to the administration of regional anesthesia."1.30Safe epidural analgesia in thirty parturients with platelet counts between 69,000 and 98,000 mm(-3). ( Beilin, Y; Comerford, M; Zahn, J, 1997)
" Although drugs can ameliorate certain toxic effects, indiscriminate use of purported antidotes can have deleterious results."1.26Toxicity of tricyclic antidepressants--kinetics, mechanism, intervention: a review. ( Irwin, HA; Preskorn, SH, 1982)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199013 (29.55)18.7374
1990's15 (34.09)18.2507
2000's14 (31.82)29.6817
2010's2 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higueras, R1
Errando, CL1
Soriano-Bru, JL1
Park, AJ1
Fisch, JM1
Fisch, JL1
Walters, MD1
Besson, M1
Desmeules, J1
Piguet, V1
Gil-Gouveia, R1
Goadsby, PJ1
Capp, PL1
de Faria, ME1
Siqueira, SR1
Cillo, MT1
Prado, EG1
de Siqueira, JT1
Ahmad, M1
Goucke, CR1
Silvanto, M1
Tarkkila, P1
Mäkelä, ML1
Rosenberg, PH1
Zaric, D1
Christiansen, C1
Pace, NL1
Punjasawadwong, Y1
Imbelloni, LE1
Beato, L1
Challapalli, V1
Tremont-Lukats, IW1
McNicol, ED1
Lau, J1
Carr, DB1
Lambert, DH1
Amir, R1
Argoff, CE1
Bennett, GJ1
Cummins, TR1
Durieux, ME1
Gerner, P1
Gold, MS1
Porreca, F1
Strichartz, GR1
Muguruma, T1
Sakura, S1
Saito, Y1
Evron, S1
Gurstieva, V1
Ezri, T1
Gladkov, V1
Shopin, S1
Herman, A1
Sidi, A1
Weitzman, S1
Neustein, SM1
Preskorn, SH1
Irwin, HA1
Maloney, JM1
Lertora, JJ1
Yarborough, J1
Millikan, LE1
Sotgiu, ML1
Biella, G1
Castagna, A1
Lacerenza, M1
Marchettini, P1
Schneider, M1
Ettlin, T1
Kaufmann, M1
Schumacher, P1
Urwyler, A1
Hampl, K1
von Hochstetter, A1
Christie, JM1
Valdes, C1
Markowsky, SJ1
Ackerman, WE1
Kalichman, MW1
Moorhouse, DF1
Powell, HC1
Myers, RR1
Beilin, Y1
Zahn, J1
Comerford, M1
Azoulay, D1
Adam, R1
Pham, P1
Salvucci, M1
Davoll, S1
Bismuth, H1
Debuire, B1
Lemoine, A1
Martínez-Bourio, R1
Arzuaga, M1
Quintana, JM1
Aguilera, L1
Aguirre, J1
Sáez-Eguilaz, JL1
Arízaga, A1
Hampl, KF1
Heinzmann-Wiedmer, S1
Luginbuehl, I1
Harms, C1
Seeberger, M1
Schneider, MC1
Drasner, K1
Liguori, GA1
Zayas, VM1
Chisholm, MF1
Lee, DS1
Bui, T1
Ferrarese, J1
Richardson, PK1
Greenberg, MS1
Youngs, EJ1
Scrivani, SJ1
Chaudry, A1
Maciewicz, RJ1
Keith, DA1
Marrouche, NF1
Reddy, RK1
Wittkowsky, AK1
Bardy, GH1
Westhues, M1
Malan, MD1
Crago, RR1
Raskin, NH1
Fishman, RA1
Drewry, A1
Gorman, DF1
Ellemann, K1
Sjögren, P1
Banning, AM1
Jensen, TS1
Smith, T1
Geertsen, P1
Petersen, P1
Kastrup, J1
Zeeberg, I1
Boysen, G1
Coulter, DM1
Yamagiwa, M1
Kubo, M1
Harada, T1
Sakakura, Y1
Phillips, OC1
Ebner, H1
Nelson, AT1
Black, MH1
Hendrix, GH1
Cline, ME1
Guntheroth, WG1
Chakmakjian, S1
Brena, SC1
Ricketts, HJ1
Wiederhielm, CA1
Rudik, VP1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain : A Pilot Study[NCT02217267]Phase 329 participants (Actual)Interventional2014-08-01Completed
The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624]Phase 480 participants (Anticipated)Interventional2019-08-01Recruiting
Effect of Intravenous Single-bolus Lidocaine Infusion Versus Intravenous Single-bolus Magnesium Sulfate Infusion on Postoperative Pain, Emotional Status and Quality of Life in Patients Undergoing Spine Fusion Surgery[NCT04776369]Phase 460 participants (Actual)Interventional2022-05-01Active, not recruiting
A Randomized, Controlled, Double-Blind Trial of 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty to Compare the Percentage of Patients in Each Group With Early Ambulation[NCT03948386]Phase 4159 participants (Actual)Interventional2019-05-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hospital Stay

length of hospital stay (NCT03948386)
Timeframe: hospital stay (0-3 days)

Interventionhours (Median)
Isobaric Bupivacaine26
Hyperbaric Bupivacaine26
Isobaric Mepivacaine22

Number of Patients With Dizziness Events

number of patients with dizziness when transitioning from lying down to sitting or standing (NCT03948386)
Timeframe: Postoperative day 2

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine11
Hyperbaric Bupivacaine7
Isobaric Mepivacaine9

Number of Patients With Transient Neurological Symptoms (TNS)

Number of patients with TNS events occurring. Transient neurological symptoms were defined as new onset of back, buttock, or thigh pain occurring after spinal anesthesia. (NCT03948386)
Timeframe: Postoperative days 0-2

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine2
Hyperbaric Bupivacaine6
Isobaric Mepivacaine5

Number of Patients With Urinary Retention Events

number of patients with inability to urinate within 8 hours of surgery OR a report of distended or painful bladder occurring on postoperative day 0 or 1, either by patient report or on palpation by nursing (NCT03948386)
Timeframe: postoperative day 1

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine6
Hyperbaric Bupivacaine8
Isobaric Mepivacaine5

Percentage Ambulating Early After Spinal Anesthesia

Is there a difference between isobaric mepivacaine, hyperbaric bupivacaine, and isobaric bupivacaine when used for spinal anesthesia in primary total hip replacement in percentage of patients that can ambulate within 3.5 hours after spinal anesthesia? (NCT03948386)
Timeframe: 3.5 hours

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine9
Hyperbaric Bupivacaine20
Isobaric Mepivacaine35

Return of Motor Function of the Thigh and Lower Leg

time to return of motor function of the thigh and lower leg (NCT03948386)
Timeframe: Postoperative day 0 (day of surgery)

Interventionminutes (Median)
Isobaric Bupivacaine148
Hyperbaric Bupivacaine123
Isobaric Mepivacaine109

Reviews

6 reviews available for lidocaine and Nervous System Disorders

ArticleYear
Neuropsychiatric side-effects of lidocaine: examples from the treatment of headache and a review.
    Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:5

    Topics: Adult; Aged; Anesthetics, Local; Bradycardia; Female; Headache; Humans; Hypertension; Lidocaine; Mal

2009
Management strategies for the treatment of neuropathic pain in the elderly.
    Drugs & aging, 2002, Volume: 19, Issue:12

    Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Capsaicin; Cog

2002
Transient neurologic symptoms after spinal anesthesia with lidocaine versus other local anesthetics: a systematic review of randomized, controlled trials.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Nervous System Diseases; Pain; Pat

2005
Systemic administration of local anesthetic agents to relieve neuropathic pain.
    The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4

    Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M

2005
Systemic administration of local anesthetic agents to relieve neuropathic pain.
    The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4

    Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M

2005
Systemic administration of local anesthetic agents to relieve neuropathic pain.
    The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4

    Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M

2005
Systemic administration of local anesthetic agents to relieve neuropathic pain.
    The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4

    Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M

2005
The role of sodium channels in chronic inflammatory and neuropathic pain.
    The journal of pain, 2006, Volume: 7, Issue:5 Suppl 3

    Topics: Anesthetics, Local; Calcium Signaling; Chronic Disease; Humans; Inflammation; Lidocaine; Nervous Sys

2006
Neurologic disorders in renal failure (first of two parts).
    The New England journal of medicine, 1976, Jan-15, Volume: 294, Issue:3

    Topics: Blood-Brain Barrier; Brain Diseases; Cerebrospinal Fluid Proteins; Diazepam; Epilepsy; Humans; Lidoc

1976

Trials

12 trials available for lidocaine and Nervous System Disorders

ArticleYear
[Epidural anaesthesia: Simulated intravascular test dose with S(+) ketamine, lidocaine and adrenaline. A prospective, randomized, double blind and placebo controlled study].
    Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:2

    Topics: Adult; Anesthesia, Epidural; Double-Blind Method; Elective Surgical Procedures; Epinephrine; Female;

2015
The influence of ambulation time on the incidence of transient neurologic symptoms after lidocaine spinal anesthesia.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:3

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Early Ambulation; Female; Humans; Knee;

2004
Lidocaine 2% with or without glucose 8% for spinal anesthesia for short orthopedic surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:8

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Glucose; Humans; Lidocaine; Male; Middle Aged

2005
Transient neurological symptoms after isobaric subarachnoid anesthesia with 2% lidocaine: the impact of needle type.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Equipment Design; Humans; Lidocaine

2007
Acute cyclosporine toxicity after liver transplantation is predicted by the lidocaine monoethylglycinexylidide test in the donor.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1997, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Cyclosporine; Female; Humans; Kidney Diseases; Lidocaine; Liver Function Te

1997
Incidence of transient neurologic symptoms after hyperbaric subarachnoid anesthesia with 5% lidocaine and 5% prilocaine.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Aged; Anesthesia, Spinal; Atmospheric Pressure; Back Pain; Female; Humans; Lidocaine; Male; M

1998
Transient neurologic symptoms after spinal anesthesia: a lower incidence with prilocaine and bupivacaine than with lidocaine.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Humans; Lidocaine; Nervous Syste

1998
Transient neurologic symptoms after spinal anesthesia with mepivacaine and lidocaine.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Arthroscopy; Back Pain; Double-Blind Meth

1998
Chronic neurogenic facial pain: lack of response to intravenous phentolamine.
    Journal of orofacial pain, 1999,Spring, Volume: 13, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Anesthetics, Local; Causalgia; Chronic Disease; Facial Pa

1999
High-dose bolus lidocaine for chemical cardioversion of atrial fibrillation: a prospective, randomized, double-blind crossover trial.
    American heart journal, 2000, Volume: 139, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cross-Over Studies; Dose-Response Relationship, D

2000
Trial of intravenous lidocaine on painful neuropathy in cancer patients.
    The Clinical journal of pain, 1989, Volume: 5, Issue:4

    Topics: Adult; Aged; Double-Blind Method; Electrocardiography; Female; Humans; Injections, Intravenous; Lido

1989
Chronic pain treatment with intravenous lidocaine.
    Neurological research, 1986, Volume: 8, Issue:3

    Topics: Double-Blind Method; Humans; Infusions, Intravenous; Lidocaine; Mexiletine; Nervous System Diseases;

1986

Other Studies

26 other studies available for lidocaine and Nervous System Disorders

ArticleYear
Transient obturator neuropathy due to local anesthesia during transobturator sling placement.
    International urogynecology journal and pelvic floor dysfunction, 2009, Volume: 20, Issue:2

    Topics: Adult; Anesthetics, Local; Bupivacaine; Female; Humans; Lidocaine; Nervous System Diseases; Obturato

2009
[What is the place of topical analgesia in neuropathic pain?].
    Revue medicale suisse, 2008, Jun-18, Volume: 4, Issue:162

    Topics: Administration, Topical; Analgesia; Analgesics; Anesthetics, Local; Humans; Lidocaine; Nervous Syste

2008
Special care dentistry: Midazolam conscious sedation for patients with neurological diseases.
    European journal of paediatric dentistry, 2010, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Autistic Disorder; Brain Damage, Chronic;

2010
Is TNS really no big deal?
    Anesthesia and analgesia, 2006, Volume: 102, Issue:2

    Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Leg; Lidocaine; Nervous System Diseases; Pain, Posto

2006
Epidural lidocaine induces dose-dependent neurologic injury in rats.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Analgesia, Epidural; Anesthetics, Local; Animals; Cauda Equina; Dose-Response Relationship, Drug; In

2006
The use of lidocaine for spinal anesthesia.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:5

    Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Equipment Design; Health Knowledge, Attitudes,

2008
Toxicity of tricyclic antidepressants--kinetics, mechanism, intervention: a review.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Child; Dose-Response Relationsh

1982
Plasma concentrations of lidocaine during hair transplantation.
    The Journal of dermatologic surgery and oncology, 1982, Volume: 8, Issue:11

    Topics: Adult; Anesthesia, Local; Dizziness; Dose-Response Relationship, Drug; Hair; Humans; Lidocaine; Male

1982
Different time-courses of i.v. lidocaine effect on ganglionic and spinal units in neuropathic rats.
    Neuroreport, 1994, Apr-14, Volume: 5, Issue:8

    Topics: Animals; Electrophysiology; Ganglia, Sensory; Injections, Intravenous; Lidocaine; Male; Nervous Syst

1994
Transient neurologic toxicity after hyperbaric subarachnoid anesthesia with 5% lidocaine.
    Anesthesia and analgesia, 1993, Volume: 76, Issue:5

    Topics: Anesthesia, Spinal; Female; Humans; Lidocaine; Middle Aged; Nervous System Diseases; Solutions; Suba

1993
Neurotoxicity of lidocaine combined with mexiletine.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:6

    Topics: Administration, Oral; Cardiomyopathies; Drug Therapy, Combination; Humans; Injections, Intravenous;

1993
Transient neurologic toxicity after subarachnoid anesthesia with hyperbaric 5% lidocaine.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:6

    Topics: Anesthesia, Spinal; Humans; Lidocaine; Nervous System Diseases; Posture; Spina Bifida Occulta; Subar

1993
Relative neural toxicity of local anesthetics.
    Journal of neuropathology and experimental neurology, 1993, Volume: 52, Issue:3

    Topics: Anesthetics, Local; Animals; Etidocaine; Female; Lidocaine; Nervous System Diseases; Procaine; Rats;

1993
Safe epidural analgesia in thirty parturients with platelet counts between 69,000 and 98,000 mm(-3).
    Anesthesia and analgesia, 1997, Volume: 85, Issue:2

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthet

1997
Cauda equina syndrome after incidental total spinal anesthesia with 2% lidocaine.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:1

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Cauda Equina; Coronary Artery Bypass; Humans; Lidocain

1998
Atypical odontalgia.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:6

    Topics: Anesthetics, Local; Facial Pain; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Nervous

1998
Rate of injection and neurotoxicity of spinal lidocaine.
    Anesthesiology, 1999, Volume: 90, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Nervous System Diseases

1999
[Local anaesthesia--modern outlook, faults and complications (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1976, Volume: 55, Issue:4

    Topics: Anesthesia, Local; Bupivacaine; Humans; Lidocaine; Mepivacaine; Nervous System Diseases; Procaine

1976
Anaesthetic considerations in idiopathic orthostatic hypotension and the Shy-Drager syndrome.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:4

    Topics: Adult; Anesthesia; Diazepam; Fecal Incontinence; Fentanyl; Humans; Hypotension, Orthostatic; Lidocai

1979
Lidocaine as an adjunct to hyperbaric therapy in decompression illness: a case report.
    Undersea biomedical research, 1992, Volume: 19, Issue:3

    Topics: Adult; Atmosphere Exposure Chambers; Combined Modality Therapy; Decompression Sickness; Humans; Infu

1992
Adverse reactions to tocainide.
    The New Zealand medical journal, 1985, Jul-10, Volume: 98, Issue:782

    Topics: Anti-Arrhythmia Agents; Drug Eruptions; Female; Humans; Lidocaine; Male; Nervous System Diseases; To

1985
[Effect of topical anesthesia of the pharyngolaryngeal mucosae on abnormal sensation in the throat].
    Nihon Jibiinkoka Gakkai kaiho, 1988, Volume: 91, Issue:3

    Topics: Adult; Aged; Anesthesia, Local; Female; Humans; Laryngeal Diseases; Lidocaine; Male; Middle Aged; Mu

1988
Neurologic complications following spinal anesthesia with lidocaine: a prospective review of 10,440 cases.
    Anesthesiology, 1969, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Spinal; Back Pain; Female; Headache; Humans; Lidocaine; Male; Methods

1969
Effects of an unusually large amount of intravenous lidocaine.
    Journal of the South Carolina Medical Association (1975), 1972, Volume: 68, Issue:9

    Topics: Cardiovascular Diseases; Hemodynamics; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged

1972
Posttraumatic sympathetic dystrophy. Dissociation of pain and vasomotor changes.
    American journal of diseases of children (1960), 1971, Volume: 121, Issue:6

    Topics: Angiography; Blood Flow Velocity; Child; Epinephrine; Foot; Humans; Injections, Spinal; Leg Injuries

1971
[Clinical aspects, diagnosis and therapy of ganglionitis of the superior cervical vegetative ganglion].
    Vrachebnoe delo, 1969, Volume: 6

    Topics: Adolescent; Adult; Aged; Female; Ganglia, Autonomic; Humans; Lidocaine; Male; Middle Aged; Neck; Ner

1969