Page last updated: 2024-10-28

lidocaine and Nephrolithiasis

lidocaine has been researched along with Nephrolithiasis in 1 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Nephrolithiasis: Formation of stones in the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"Intravenous hydromorphone was superior to intravenous lidocaine both for general abdominal pain and a subset of patients with nephrolithiasis."9.30Randomized Trial of Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain in the Emergency Department. ( Afrifa, F; Chertoff, A; Chinn, E; Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Naeem, F; Pearlman, S; Wollowitz, A; Zias, E, 2019)
"Intravenous hydromorphone was superior to intravenous lidocaine both for general abdominal pain and a subset of patients with nephrolithiasis."5.30Randomized Trial of Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain in the Emergency Department. ( Afrifa, F; Chertoff, A; Chinn, E; Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Naeem, F; Pearlman, S; Wollowitz, A; Zias, E, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chinn, E1
Friedman, BW1
Naeem, F1
Irizarry, E1
Afrifa, F1
Zias, E1
Jones, MP1
Pearlman, S1
Chertoff, A1
Wollowitz, A1
Gallagher, EJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain. A Randomized Trial[NCT03300674]Phase 4154 participants (Actual)Interventional2018-01-10Completed
High Dose Intravenous Lidocaine vs Hydromorphone for Acute Abdominal Pain in the Emergency Department: A Randomized, Comparative Efficacy Trial[NCT04398316]Phase 4187 participants (Anticipated)Interventional2021-02-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adverse Events

Any new symptom development after administration of investigational medication (NCT03300674)
Timeframe: 4 hours

InterventionParticipants (Count of Participants)
Intravenous Hydromorphone28
Intravenous Lidocaine23

Change in 0-10 Pain Scale Between Baseline and 90 Minutes

Participants were asked to describe their pain on a scale from 0 to 10 with 0= no pain and 10= the worst pain imaginable (NCT03300674)
Timeframe: up to 90 minutes

Interventionunits on a scale (Mean)
Intravenous Hydromorphone5.0
Intravenous Lidocaine3.8

Rescue Medication

no need for off-protocol parenteral pain medication during the ED visit. The following parenteral medications will be considered off protocol pain medication: any opioid, any non-steroidal anti-inflammatory drug (NCT03300674)
Timeframe: 4 hours

InterventionParticipants (Count of Participants)
Intravenous Hydromorphone20
Intravenous Lidocaine39

Trials

1 trial available for lidocaine and Nephrolithiasis

ArticleYear
Randomized Trial of Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain in the Emergency Department.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Abdominal Pain; Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Loc

2019
Randomized Trial of Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain in the Emergency Department.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Abdominal Pain; Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Loc

2019
Randomized Trial of Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain in the Emergency Department.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Abdominal Pain; Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Loc

2019
Randomized Trial of Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain in the Emergency Department.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Abdominal Pain; Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Loc

2019