Page last updated: 2024-10-28

lidocaine and Neoplasm Metastasis

lidocaine has been researched along with Neoplasm Metastasis in 10 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"4T1 murine breast cancer cells were exposed to lidocaine and/or bosutinib."8.02The Effect of Lidocaine and Bosutinib on 4T1 Murine Breast Cancer Cell Behaviour ( Buggy, DJ; Crowley, PD; Wall, TP, 2021)
"Lidocaine has been shown to inhibit the invasion and metastasis of breast cancer, but the mechanism still remains unclear."8.02Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation. ( He, C; Li, B; Tu, Y; Xu, H; Zou, W, 2021)
"4T1 murine breast cancer cells were exposed to lidocaine and/or bosutinib."4.02The Effect of Lidocaine and Bosutinib on 4T1 Murine Breast Cancer Cell Behaviour ( Buggy, DJ; Crowley, PD; Wall, TP, 2021)
"Lidocaine has been shown to inhibit the invasion and metastasis of breast cancer, but the mechanism still remains unclear."4.02Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation. ( He, C; Li, B; Tu, Y; Xu, H; Zou, W, 2021)
"Metastatic breast and colon cancer cells express neonatal and adult splice variants of NaV1."1.40Potent inhibition by ropivacaine of metastatic colon cancer SW620 cell invasion and NaV1.5 channel function. ( Baptista-Hon, DT; Hales, TG; Lee, NH; Lydon, EL; Owen, SJ; Robertson, FM; Robertson, GB; Rogers, GW, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Balaban, O1
Aydın, T1
Yaman, M1
Wall, TP1
Crowley, PD2
Buggy, DJ2
Li, B1
Xu, H1
He, C1
Zou, W1
Tu, Y1
Johnson, MZ1
Foley, AG1
Xue, C1
Connolly, C1
Gallagher, HC1
Baptista-Hon, DT1
Robertson, FM1
Robertson, GB1
Owen, SJ1
Rogers, GW1
Lydon, EL1
Lee, NH1
Hales, TG1
Piegeler, T1
Votta-Velis, EG1
Liu, G1
Place, AT1
Schwartz, DE1
Beck-Schimmer, B1
Minshall, RD1
Borgeat, A1
Massey, GV1
Pedigo, S1
Dunn, NL1
Grossman, NJ1
Russell, EC1
HOLLING, HE1
DANIELSON, GK1
HAMILTON, RW1
BLAKEMORE, WS1
BRODEY, RS1
Due, J1
Bloch, S1
Quantrill, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Epidural Anesthesia-analgesia on Long-term Survival in Patients After Lung Cancer Surgery: A Randomized Controlled Trial[NCT02801409]400 participants (Actual)Interventional2015-05-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

10 other studies available for lidocaine and Neoplasm Metastasis

ArticleYear
Ultrasound-guided erector spinae plane catheter placement for long-term continuous analgesia in pulmonary malignancy.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2019, Volume: 31, Issue:3

    Topics: Aged; Anesthetics, Local; Catheters, Indwelling; Female; Humans; Lidocaine; Lung Neoplasms; Mesothel

2019
The Effect of Lidocaine and Bosutinib on 4T1 Murine Breast Cancer Cell Behaviour
    Anticancer research, 2021, Volume: 41, Issue:6

    Topics: Aniline Compounds; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Diseas

2021
Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation.
    The Journal of toxicological sciences, 2021, Volume: 46, Issue:7

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Lidocaine; Male

2021
Effect of perioperative lidocaine on metastasis after sevoflurane or ketamine-xylazine anaesthesia for breast tumour resection in a murine model.
    British journal of anaesthesia, 2018, Volume: 121, Issue:1

    Topics: Adrenergic alpha-Agonists; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Local; A

2018
Potent inhibition by ropivacaine of metastatic colon cancer SW620 cell invasion and NaV1.5 channel function.
    British journal of anaesthesia, 2014, Volume: 113 Suppl 1

    Topics: Adult; Age Factors; Amides; Anesthetics, Local; Cell Movement; Collagen; Colonic Neoplasms; Dose-Res

2014
Antimetastatic potential of amide-linked local anesthetics: inhibition of lung adenocarcinoma cell migration and inflammatory Src signaling independent of sodium channel blockade.
    Anesthesiology, 2012, Volume: 117, Issue:3

    Topics: Adenocarcinoma; Amides; Anesthetics, Local; Cell Line, Tumor; Cell Movement; Humans; Intercellular A

2012
Continuous lidocaine infusion for the relief of refractory malignant pain in a terminally ill pediatric cancer patient.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:7

    Topics: Analgesics, Opioid; Child, Preschool; Female; Humans; Injections, Spinal; Lidocaine; Neoplasm Metast

2002
HYPERTROPHIC PULMONARY OSTEOARTHROPATHY.
    The Journal of thoracic and cardiovascular surgery, 1963, Volume: 46

    Topics: Blood Circulation; Carcinoma; Carcinoma, Bronchogenic; Dog Diseases; Dogs; Lidocaine; Lung Neoplasms

1963
[Easing of a painful death].
    Nederlands tijdschrift voor geneeskunde, 1977, Dec-31, Volume: 121, Issue:53

    Topics: Adult; Aged; Celiac Plexus; Ethanol; Female; Humans; Injections, Spinal; Lidocaine; Lung Neoplasms;

1977
The radiology of nasopharyngeal tumours, including positive-contrast nasopharyngography.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1968, Oct-12, Volume: 42, Issue:39

    Topics: Catheterization; Contrast Media; Humans; Lidocaine; Methods; Nasopharyngeal Neoplasms; Nasopharynx;

1968