Page last updated: 2024-10-28

lidocaine and Neck Pain

lidocaine has been researched along with Neck Pain in 30 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Neck Pain: Discomfort or more intense forms of pain that are localized to the cervical region. This term generally refers to pain in the posterior or lateral regions of the neck.

Research Excerpts

ExcerptRelevanceReference
"Cervical radiculopathy is a mixed pain syndrome characterized by neuropathic, skeletal and myofascial pain."5.42[Conservative treatment of cervical radiculopathy with 5% lidocaine medicated plaster]. ( Mattozzi, I, 2015)
"We conducted a retrospective review of the charts of thirty-four patients with neck pain who met three criteria for the diagnosis of shoulder impingement syndrome: (1) a positive impingement sign with pain referred to the neck, (2) radiographic abnormalities, and (3) relief of neck pain after injection of lidocaine and cortisone into the subacromial space."3.72Shoulder impingement presenting as neck pain. ( Gorski, JM; Schwartz, LH, 2003)
"Acute nonspecific neck pain is one of the major public health problems lacking efficient treatments."2.87Single intracutaneous injection of local anesthetics and steroids alleviates acute nonspecific neck pain: A CONSORT-perspective, randomized, controlled clinical trial. ( Cui, JZ; Geng, ZS; Wang, XL; Yang, XN; Zhang, XB; Zhang, XL; Zhang, YH, 2018)
"Treatment with lidocaine alone or with the steroid resulted in decreases of 4."2.82Clinical Efficacy of Epidural Injections of Local Anesthetic Alone or Combined with Steroid for Neck Pain: A Systematic Review and Meta-Analysis. ( Bao, SX; Li, BZ; Li, Y; Liu, MG; Tang, WH; Zhou, L, 2022)
"The chronic cervical facet joint pain was diagnosed with cervical facet joint nerve blocks at a prevalence of 49."1.56Assessment of Prevalence of Cervical Facet Joint Pain with Diagnostic Cervical Medial Branch Blocks: Analysis Based on Chronic Pain Model. ( Cash, KA; Hirsch, JA; Kaye, AD; Kosanovic, R; Manchikanti, L; Pampati, V; Soin, A, 2020)
"Axial neck pain is originated from sinuvertebral nerve located in ventral epidural spaces, which has been described to be related to central or paramedian disc herniation."1.43Comparison of Clinical Efficacy Between Interlaminar and Transforaminal Epidural Injection in Patients With Axial Pain due to Cervical Disc Herniation. ( Lee, JH; Lee, SH, 2016)
"Cervical radiculopathy is a mixed pain syndrome characterized by neuropathic, skeletal and myofascial pain."1.42[Conservative treatment of cervical radiculopathy with 5% lidocaine medicated plaster]. ( Mattozzi, I, 2015)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (36.67)29.6817
2010's16 (53.33)24.3611
2020's3 (10.00)2.80

Authors

AuthorsStudies
Li, BZ1
Tang, WH1
Li, Y1
Zhou, L1
Liu, MG1
Bao, SX1
Pasuhirunnikorn, P1
Tanasansomboon, T1
Singhatanadgige, W1
Yingsakmongkol, W1
Chalermkitpanit, P1
Manchikanti, L3
Kosanovic, R1
Cash, KA3
Pampati, V3
Soin, A1
Kaye, AD1
Hirsch, JA1
McCormick, ZL1
Nelson, A1
Kendall, MC1
McCarthy, RJ1
Nagpal, G1
Walega, DR1
Ulusoy, OL1
Alis, D1
Mutlu, A1
Colakoglu, B1
Sirvanci, M1
Yang, XN1
Geng, ZS1
Zhang, XL1
Zhang, YH1
Wang, XL1
Zhang, XB1
Cui, JZ1
Lee, DW1
Huston, C1
Tamaki, A1
Thuener, J1
Weidenbecher, M1
Ustun, N1
Arslan, F1
Mansuroglu, A1
Inanoglu, D1
Yagız, AE1
Guler, H1
Turhanoglu, AD1
Malla, Y2
Kang, SS1
Kim, IS1
Park, JH1
Hong, SJ1
Shin, HK1
Song, CG1
Yoo, YC1
Shin, KM1
Mattozzi, I1
Peloso, PM2
Gross, A3
Haines, T3
Trinh, K4
Goldsmith, CH4
Burnie, SJ1
Lee, JH1
Lee, SH1
Bereczki, D1
Peto, N1
Szegedi, N1
Moon, JJ1
Ahn, MW1
Ahn, HS1
Lee, SJ1
Lee, DY1
Kim, EC1
Kim, MS1
Bahgat, M1
Bahgat, Y1
Bahgat, A1
Wargo, BW1
Gorski, JM1
Schwartz, LH1
Botwin, KP1
Castellanos, R1
Rao, S1
Hanna, AF1
Torres-Ramos, FM1
Gruber, RD1
Bouchlas, CG1
Fuoco, GS1
Kedlaya, D1
Peloso, P2
Aker, P2
Kim, KH1
Choi, SH1
Kim, TK1
Shin, SW1
Kim, CH1
Kim, JI1
Heckmann, JG1
Maihöfner, C1
Lanz, S1
Rauch, C1
Neundörfer, B1
Gross, AR1
Haines, TA1
Naja, ZM1
El-Rajab, M1
Al-Tannir, MA1
Ziade, FM1
Tawfik, OM1
Burnie, S1
Tsukiyama, Y1
Baba, K1
Clark, GT1
Prasad, KC1
Kamath, MP1
Reddy, KJ1
Raju, K1
Agarwal, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial[NCT03127137]Phase 4123 participants (Actual)Interventional2018-08-01Completed
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized[NCT03382925]Phase 416 participants (Actual)Interventional2017-12-20Terminated (stopped due to Not enough cervical interlaminar patients who meet criteria in order to meet recruitment goals.)
Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012]Phase 410 participants (Actual)Interventional2017-05-02Terminated (stopped due to Poor enrollment.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Strength in Both Groups After CESI.

Change in strength in both groups greater than or equal to 20% weakness in one or more myotomes 30 minutes after CESI using a hand held Dynamometer. (NCT03127137)
Timeframe: 30 minutes after the CESI procedure

,
InterventionParticipants (Count of Participants)
Yes, greater or equal to 20% weakness in greater or equal to 1 or more myotomeNo, greater or equal to 20% weakness in greater or equal to 1 or more myotome
Experimental Group 1 With Lidocaine2535
Experimental Group 2 With Saline3030

Number of Participants With a Responder Rate Greater Than 50% on the Numeric Rating Pain Scale (NRS) Improvement

Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months

InterventionParticipants (Count of Participants)
Ketorolac1
Lidocaine0
Dexamethasone0

Brief Pain Inventory (BPI) - Modified

The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months

Interventionscore on a scale (Number)
Participant Number #3 at BaselineParticipant Number #3 at 3 MonthsParticipant Number #8 at BaselineParticipant #8 at 3 Months
Ketorolac8353

Numeric Rating Pain Scale (NRS) at Baseline and Three Months.

TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)

Interventionscore on a scale (Number)
Participant Number 3 at BaselineParticipant Number 3 at 3 MonthsParticipant Number 8 at BaselineParticipant Number 8 at 3 Months
Ketorolac8353

Reviews

8 reviews available for lidocaine and Neck Pain

ArticleYear
Clinical Efficacy of Epidural Injections of Local Anesthetic Alone or Combined with Steroid for Neck Pain: A Systematic Review and Meta-Analysis.
    BioMed research international, 2022, Volume: 2022

    Topics: Anesthetics, Local; Humans; Injections, Epidural; Lidocaine; Neck Pain; Reproducibility of Results;

2022
Superior Laryngeal Nerve Neuralgia: Case Series and Review of Anterior Neck Pain Syndromes.
    Ear, nose, & throat journal, 2019, Volume: 98, Issue:8

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

2019
WITHDRAWN: Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2015, May-21, Issue:5

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2015
Eagle's syndrome, a rare cause of neck pain.
    BMJ case reports, 2012, Jul-25, Volume: 2012

    Topics: Adult; Anesthetics, Local; Deglutition Disorders; Diagnosis, Differential; Humans; Lidocaine; Male;

2012
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2005, Apr-18, Issue:2

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Humans; Lidocaine; Met

2005
Medicinal and injection therapies for mechanical neck disorders: a Cochrane systematic review.
    The Journal of rheumatology, 2006, Volume: 33, Issue:5

    Topics: Administration, Oral; Anesthetics, Local; Anti-Inflammatory Agents; Botulinum Toxins; Humans; Inject

2006
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
An evidence-based assessment of occlusal adjustment as a treatment for temporomandibular disorders.
    The Journal of prosthetic dentistry, 2001, Volume: 86, Issue:1

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Biofeedback, Psychology; Bruxism

2001

Trials

7 trials available for lidocaine and Neck Pain

ArticleYear
Comparative Outcome of Lidocaine Versus Bupivacaine for Cervical Medial Branch Block in Chronic Cervical Facet Arthropathy: A Randomized Double-Blind Study.
    World neurosurgery, 2023, Volume: 175

    Topics: Anesthetics, Local; Bupivacaine; Double-Blind Method; Humans; Joint Diseases; Lidocaine; Neck Pain;

2023
Single intracutaneous injection of local anesthetics and steroids alleviates acute nonspecific neck pain: A CONSORT-perspective, randomized, controlled clinical trial.
    Medicine, 2018, Volume: 97, Issue:28

    Topics: Adult; Anesthetics, Local; Bupivacaine; Drug Monitoring; Female; Glucocorticoids; Humans; Injections

2018
Efficacy of EMLA cream phonophoresis comparison with ultrasound therapy on myofascial pain syndrome of the trapezius: a single-blind, randomized clinical study.
    Rheumatology international, 2014, Volume: 34, Issue:4

    Topics: Adult; Anesthetics, Local; Biomechanical Phenomena; Disability Evaluation; Female; Humans; Lidocaine

2014
Two-year follow-up results of fluoroscopic cervical epidural injections in chronic axial or discogenic neck pain: a randomized, double-blind, controlled trial.
    International journal of medical sciences, 2014, Volume: 11, Issue:4

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Injections, Epidural; Lidocaine; Mal

2014
Management of chronic pain of cervical disc herniation and radiculitis with fluoroscopic cervical interlaminar epidural injections.
    International journal of medical sciences, 2012, Volume: 9, Issue:6

    Topics: Adult; Anesthetics, Local; Betamethasone; Cervical Vertebrae; Chronic Pain; Double-Blind Method; Fem

2012
Cervical facet joint injections in the neck and shoulder pain.
    Journal of Korean medical science, 2005, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Female; Humans; Injections; L

2005
Repetitive occipital nerve blockade for cervicogenic headache: expanded case report of 47 adults.
    Pain practice : the official journal of World Institute of Pain, 2006, Volume: 6, Issue:4

    Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Vertebrae; Clonidine; Dose-Response Relations

2006

Other Studies

15 other studies available for lidocaine and Neck Pain

ArticleYear
Assessment of Prevalence of Cervical Facet Joint Pain with Diagnostic Cervical Medial Branch Blocks: Analysis Based on Chronic Pain Model.
    Pain physician, 2020, Volume: 23, Issue:6

    Topics: Adult; Anesthetics, Local; Arthralgia; Bupivacaine; Chronic Pain; Female; Humans; Lidocaine; Male; M

2020
Does Cervical Interlaminar Epidural Steroid Injection with Low-Dose Lidocaine Cause Objective Upper Extremity Weakness? A Preliminary Study.
    Pain medicine (Malden, Mass.), 2017, Dec-01, Volume: 18, Issue:12

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Arm; Female; Glucocorticoids; Hand Strength; Hu

2017
The preliminary results of a new CT-guided periradicular cervical steroid injection technique: safety and feasibility of the lateral peri-isthmic approach in 28 patients.
    Skeletal radiology, 2018, Volume: 47, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Contrast Media; Dexamethasone; Female; Humans; I

2018
Fluoroscopically-Guided Cervical Zygapophyseal Therapeutic Joint Injections May Reduce the Need for Radiofrequency.
    Pain physician, 2018, Volume: 21, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Arthralgia; Betamethasone; Bupivacaine; Female; Humans; Injections,

2018
Short-term changes of intraocular pressure after cervical interlaminar epidural injection: a pilot study.
    British journal of anaesthesia, 2014, Volume: 113, Issue:5

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Epidural; Anesthetics, Local; Female; Funct

2014
[Conservative treatment of cervical radiculopathy with 5% lidocaine medicated plaster].
    Minerva medica, 2015, Volume: 106, Issue:1

    Topics: Administration, Topical; Anesthetics, Local; Casts, Surgical; Female; Humans; Lidocaine; Male; Mesot

2015
Comparison of Clinical Efficacy Between Interlaminar and Transforaminal Epidural Injection in Patients With Axial Pain due to Cervical Disc Herniation.
    Medicine, 2016, Volume: 95, Issue:4

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Back Pain; Cervical Vertebrae; Dexamethasone; D

2016
Transient deficits after inadvertent intrathecal trigger-point injection with lidocaine.
    Neurology, 2016, 08-23, Volume: 87, Issue:8

    Topics: Adult; Anesthetics, Local; Dysarthria; Female; Humans; Injections, Spinal; Lidocaine; Neck Pain; Par

2016
Usefulness of K-Point Injection for the Nonspecific Neck Pain in So-Called K-Point Syndrome.
    Clinics in orthopedic surgery, 2016, Volume: 8, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dexamethasone; Female; Fibromyalgia; Humans; Inj

2016
Acute bilateral retinal hemorrhages and unilateral sixth cranial nerve palsy after inadvertent epidural anaesthetic injection and subsequent dural puncture.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2010, Volume: 45, Issue:5

    Topics: Abducens Nerve Diseases; Acute Disease; Analgesia, Epidural; Anesthetics, Local; Diplopia; Female; F

2010
Shoulder impingement presenting as neck pain.
    The Journal of bone and joint surgery. American volume, 2003, Volume: 85, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Chronic Disease; Diagnosis, Differe

2003
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
Complications of fluoroscopically guided interlaminar cervical epidural injection.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:9

    Topics: Cervical Vertebrae; Fluoroscopy; Humans; Injections, Epidural; Intervertebral Disc Displacement; Lid

2003
Transient tetraplegia after cervical facet joint injection for chronic neck pain administered without imaging guidance.
    Clinical neurology and neurosurgery, 2006, Volume: 108, Issue:7

    Topics: Adult; Anesthetics, Local; Arteries; Atropine; Bradycardia; Cervical Vertebrae; Chronic Disease; Dia

2006
Elongated styloid process (Eagle's syndrome): a clinical study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2002, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Calcinosis; Deglutition Disorders; Diagnosis, Different

2002