lidocaine has been researched along with Nasal Polyps in 8 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Nasal Polyps: Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bupivacaine help the lower pain values and less additional painkiller need after FESS." | 2.82 | Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? ( Arıkan, OK; Haytoğlu, S; Kuran, G; Muluk, NB, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Tangbumrungtham, N | 1 |
| Hwang, PH | 1 |
| Maul, X | 1 |
| Borchard, NA | 1 |
| Dholakia, SS | 1 |
| Patel, ZM | 1 |
| Nayak, JV | 1 |
| Choby, G | 1 |
| Haytoğlu, S | 1 |
| Kuran, G | 1 |
| Muluk, NB | 1 |
| Arıkan, OK | 1 |
| Jindal, M | 1 |
| Sharma, N | 1 |
| Parekh, N | 1 |
| EL-BARBARY, A | 1 |
| BOTROS, KM | 1 |
| Cohen-Kerem, R | 1 |
| Brown, S | 1 |
| Villaseñor, LV | 1 |
| Witterick, I | 1 |
| Williams, PJ | 1 |
| Bailey, PM | 1 |
| Kunzelmann, K | 1 |
| Pavenstädt, H | 1 |
| Greger, R | 1 |
| Woldorf, NM | 1 |
| Pastore, PN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery[NCT05867342] | Phase 4 | 40 participants (Actual) | Interventional | 2017-05-12 | Completed | ||
| The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing[NCT04519463] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2020-09-30 | Not yet recruiting | ||
| Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?[NCT03266926] | 140 participants (Actual) | Observational [Patient Registry] | 2017-02-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
| Intervention | minutes (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 72.05 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 54.23 |
(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
| Intervention | mL (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 95.25 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 91.63 |
Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
| Intervention | days (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 2.85 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.73 |
A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
| Intervention | pledgets (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 3.25 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.63 |
Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
| Intervention | nostrils (Count of Units) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 7 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 5 |
Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
| Intervention | score on a scale (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 2.38 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.2 |
The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)
| Intervention | score on a scale (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 3.54 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 3.23 |
3 trials available for lidocaine and Nasal Polyps
| Article | Year |
|---|---|
The effect of topical epinephrine 1:1000 with and without infiltration of 1% lidocaine with epinephrine 1:100,000 on endoscopic surgical field visualization: a double-blind randomized controlled study.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Chronic Disease; Dou | 2020 |
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe | 2016 |
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe | 2016 |
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe | 2016 |
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe | 2016 |
Epinephrine/Lidocaine injection vs. saline during endoscopic sinus surgery.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Blood Loss, Surgical | 2008 |
5 other studies available for lidocaine and Nasal Polyps
| Article | Year |
|---|---|
Intraoperative dilated pupil during nasal polypectomy.
Topics: Anesthetics, Local; Drug Combinations; Endoscopy; Humans; Intraoperative Complications; Lidocaine; M | 2009 |
THE EFFECT OF TEMPORARY AUTONOMIC BLOCK ON THE SO-CALLED ALLERGIC CONDITIONS OF THE NASAL MUCOSA: "A PRELIMINARY REPORT".
Topics: Autonomic Nerve Block; Humans; Lidocaine; Nasal Mucosa; Nasal Polyps; Rhinitis, Allergic, Seasonal; | 1965 |
Management of failed oral fibreoptic intubation with laryngeal mask airway insertion under topical anaesthesia.
Topics: Anesthesia, Local; Fiber Optic Technology; Humans; Intubation, Intratracheal; Laryngeal Masks; Lidoc | 1993 |
Characterization of potassium channels in respiratory cells. II. Inhibitors and regulation.
Topics: Adenosine Triphosphate; Barium; Calcium; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; | 1989 |
Extreme epinephrine sensitivity with a general anesthesia.
Topics: Adult; Anesthesia, Inhalation; Arrhythmias, Cardiac; Blood Pressure; Child; Drug Hypersensitivity; D | 1972 |