Page last updated: 2024-10-28

lidocaine and Myoclonic Jerk

lidocaine has been researched along with Myoclonic Jerk in 19 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Propofol is associated with a high incidence of injection pain in children, even if given together with lidocaine."9.12Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine. ( Eksborg, S; Lönnqvist, PA; Nyman, Y; Palm, C; Von Hofsten, K, 2006)
"Diazepam was used to control myoclonus until the effects of morphine abated."5.38Severe pruritus and myoclonus following intrathecal morphine administration in a dog. ( Iff, I; Mosing, M; Valeskini, K, 2012)
"Propofol is associated with a high incidence of injection pain in children, even if given together with lidocaine."5.12Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine. ( Eksborg, S; Lönnqvist, PA; Nyman, Y; Palm, C; Von Hofsten, K, 2006)
"Pretreatment with lidocaine significantly reduced both the incidence and severity of myoclonic movements."2.75Lidocaine pretreatment reduces the frequency and severity of myoclonus induced by etomidate. ( Akkaya, T; Bedirli, N; Gultop, F; Gumus, H, 2010)
"Pretreatment with lidocaine could be served as one effective approach to decrease both the incidence and the severity of etomidate-induced myoclonus, with limited influence on the hemodynamic stability of patients."2.58Pretreatment with lidocaine reduces both incidence and severity of etomidate-induced myoclonus: a meta-analysis of randomized controlled trials. ( Lang, B; Li, F; Lin, Y; Yang, C; Zhang, L; Zhang, W, 2018)
"Etomidate-induced myoclonus, a seizure-like movement, is of interest to anesthetists."1.91Etomidate-Induced Myoclonus in Sprague-Dawley Rats Involves Neocortical Glutamate Accumulation and N -Methyl- d -Aspartate Receptor Activity. ( Chang, P; Feng, Y; Kang, Y; Li, CY; Liao, P; Liu, J; Zhang, WS, 2023)
"Etomidate-induced myoclonus is common in clinical anesthesia."1.72Etomidate-induced myoclonus correlates with the dysfunction of astrocytes and glutamate transporters in the neocortex of Sprague-Dawley rats. ( Feng, Y; Liu, J; Zhang, WS, 2022)
"Spinal myoclonus following neuraxial anesthesia is rare."1.43Myoclonus-like involuntary movements following cesarean delivery epidural anesthesia. ( Hong, EP; Kang, HY; Kang, JM; Lee, SM; Lee, SW; Park, SW; Sim, YH, 2016)
"To evaluate the incidence of myoclonus (involuntary movements during anaesthesia, unrelated to inadequate hypnosis or analgesia, and of sufficient severity to require treatment) in dogs anaesthetized with a TIVA of propofol with or without the use of fentanyl."1.42The incidence of spontaneous movements (myoclonus) in dogs undergoing total intravenous anaesthesia with propofol. ( Cattai, A; Franci, P; Natale, V; Rabozzi, R, 2015)
"Diazepam was used to control myoclonus until the effects of morphine abated."1.38Severe pruritus and myoclonus following intrathecal morphine administration in a dog. ( Iff, I; Mosing, M; Valeskini, K, 2012)
"A 3."1.38CENTRAL NERVOUS SYSTEM LIGNOCAINE TOXICITY IN AN INFANT FOLLOWING VENTRICULO-PERITONEAL SHUNT AND SPINA BIFIDA REPAIR: A CASE REPORT. ( Kituu, N; Kituyi, PW; Mugenya, WO, 2012)
"The concept of peripheral myoclonus is not yet fully accepted by the medical community because of the difficulty in establishing a cause-and-effect relationship between trauma and subsequent movement disorders."1.35Myoclonus of peripheral origin: two case reports. ( Cassim, F; Defebvre, L; Destée, A; Houdayer, E; Kreisler, A; Krystkowiak, P; Tyvaert, L, 2009)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's3 (15.79)18.2507
2000's3 (15.79)29.6817
2010's6 (31.58)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Feng, Y2
Liu, J2
Zhang, WS2
Chang, P1
Kang, Y1
Liao, P1
Li, CY1
Lang, B1
Zhang, L1
Yang, C1
Lin, Y1
Zhang, W1
Li, F1
Iff, I1
Valeskini, K1
Mosing, M1
Cattai, A1
Rabozzi, R1
Natale, V1
Franci, P1
Kituu, N1
Mugenya, WO1
Kituyi, PW1
Kang, HY1
Lee, SW1
Hong, EP1
Sim, YH1
Lee, SM1
Park, SW1
Kang, JM1
Tyvaert, L1
Krystkowiak, P1
Cassim, F1
Houdayer, E1
Kreisler, A1
Destée, A1
Defebvre, L1
Pasquier, P1
Ausset, S1
Pelee De Saint Maurice, G1
Vest, P1
Mazoit, JX1
Auroy, Y1
Gultop, F1
Akkaya, T1
Bedirli, N1
Gumus, H1
Nyman, Y1
Von Hofsten, K1
Palm, C1
Eksborg, S1
Lönnqvist, PA1
Shea, JJ1
Emmett, JR1
Dreskin, S1
Bajwa, ZH1
Lehmann, L1
Warfield, CA1
Khalil, SN1
Howard, G1
Mankarious, R1
Campos, C1
Kellaway, J1
Chuang, AZ1
Ruiz, R1
Raskin, NH1
Fishman, RA1
Kirk, A1
Heilman, KM1
Hambert, O2
Petersén, I2
Tenser, RB1
Corbett, JJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Pretreatment of Lignocaine Versus Midazolam in the Prevention of Etomidate Induced Myoclonus[NCT04921046]Phase 4224 participants (Actual)Interventional2015-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for lidocaine and Myoclonic Jerk

ArticleYear
Pretreatment with lidocaine reduces both incidence and severity of etomidate-induced myoclonus: a meta-analysis of randomized controlled trials.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Anesthetics, Local; Etomidate; Humans; Lidocaine; Myoclonus; Randomized Controlled Trials as Topic

2018
Neurologic disorders in renal failure (first of two parts).
    The New England journal of medicine, 1976, Jan-15, Volume: 294, Issue:3

    Topics: Blood-Brain Barrier; Brain Diseases; Cerebrospinal Fluid Proteins; Diazepam; Epilepsy; Humans; Lidoc

1976

Trials

3 trials available for lidocaine and Myoclonic Jerk

ArticleYear
Lidocaine pretreatment reduces the frequency and severity of myoclonus induced by etomidate.
    Journal of anesthesia, 2010, Volume: 24, Issue:2

    Topics: Anesthetics, Local; Double-Blind Method; Etomidate; Humans; Hypnotics and Sedatives; Lidocaine; Myoc

2010
Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine.
    British journal of anaesthesia, 2006, Volume: 97, Issue:4

    Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics, Intravenous; Anest

2006
Alfentanil decreases the excitatory phenomena of sodium methohexital.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthetics, Intravenous; Costs and Cost Analysis; Doubl

1998

Other Studies

14 other studies available for lidocaine and Myoclonic Jerk

ArticleYear
Etomidate-induced myoclonus correlates with the dysfunction of astrocytes and glutamate transporters in the neocortex of Sprague-Dawley rats.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:17

    Topics: Amino Acid Transport System X-AG; Animals; Anticonvulsants; Astrocytes; Etomidate; Glutamic Acid; Hy

2022
Etomidate-Induced Myoclonus in Sprague-Dawley Rats Involves Neocortical Glutamate Accumulation and N -Methyl- d -Aspartate Receptor Activity.
    Anesthesia and analgesia, 2023, 07-01, Volume: 137, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Etomidate; Glutamic Acid; Lidocaine; Male; Myoclonus; Neocortex;

2023
Severe pruritus and myoclonus following intrathecal morphine administration in a dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2012, Volume: 53, Issue:9

    Topics: Analgesics, Opioid; Animals; Bupivacaine; Dog Diseases; Dogs; Female; Lidocaine; Morphine; Myoclonus

2012
The incidence of spontaneous movements (myoclonus) in dogs undergoing total intravenous anaesthesia with propofol.
    Veterinary anaesthesia and analgesia, 2015, Volume: 42, Issue:1

    Topics: Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; Female

2015
CENTRAL NERVOUS SYSTEM LIGNOCAINE TOXICITY IN AN INFANT FOLLOWING VENTRICULO-PERITONEAL SHUNT AND SPINA BIFIDA REPAIR: A CASE REPORT.
    East African medical journal, 2012, Volume: 89, Issue:2

    Topics: Anesthetics, Local; Anticonvulsants; Diazepam; Humans; Hydrocephalus; Infant; Intraoperative Care; L

2012
Myoclonus-like involuntary movements following cesarean delivery epidural anesthesia.
    Journal of clinical anesthesia, 2016, Volume: 34

    Topics: Administration, Intravenous; Adult; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Ob

2016
Myoclonus of peripheral origin: two case reports.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jan-30, Volume: 24, Issue:2

    Topics: Adolescent; Amputation Stumps; Anterior Horn Cells; Anti-Dyskinesia Agents; Arm Injuries; Botulinum

2009
Convulsions associated with a low plasma level of local anaesthetics.
    British journal of anaesthesia, 2009, Volume: 103, Issue:5

    Topics: Amides; Anesthetics, Local; Female; Humans; Lidocaine; Middle Aged; Myoclonus; Ropivacaine

2009
The medical treatment of tinnitus.
    The Journal of laryngology and otology. Supplement, 1981, Issue:4

    Topics: Adult; Carbamazepine; Diethylcarbamazine; Female; Humans; Lidocaine; Myoclonus; Phenytoin; Primidone

1981
Polymyoclonus resulting from possible accidental subdural injection of local anesthetic.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:3

    Topics: Anesthetics, Local; Humans; Hypotension; Injections, Epidural; Lidocaine; Middle Aged; Myoclonus; St

1997
Auricular myoclonus.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1991, Volume: 18, Issue:4

    Topics: Adult; Ear Diseases; Ear, External; Electrodiagnosis; Facial Nerve; Humans; Lidocaine; Male; Myoclon

1991
Clinical, electroencephalographical and neuropharmacological studies in syndromes of progressive myoclonus epilepsy.
    Acta neurologica Scandinavica, 1970, Volume: 46, Issue:2

    Topics: Administration, Oral; Adrenocorticotropic Hormone; Adult; Amobarbital; Benzazepines; Chloral Hydrate

1970
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F

1974
Clinical and electroencephalographic studies of responses to lidocaine and chlormethiazole in progressive myoclonus epilepsy.
    Acta psychiatrica Scandinavica. Supplementum, 1966, Volume: 192

    Topics: Adolescent; Adult; Chlormethiazole; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans;

1966