lidocaine has been researched along with Mydriasis in 16 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Mydriasis: Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia." | 9.51 | Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022) |
| "31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children." | 8.31 | Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023) |
| "02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia." | 5.51 | Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022) |
| "To evaluate the effects of peribulbar anesthesia (sub-Tenon injection of lidocaine hydrochloride) on akinesia of extraocular muscles, mydriasis, and intraoperative and postoperative analgesia in dogs undergoing phacoemulsification." | 5.17 | Effects of peribulbar anesthesia (sub-Tenon injection of a local anesthetic) on akinesia of extraocular muscles, mydriasis, and intraoperative and postoperative analgesia in dogs undergoing phacoemulsification. ( Ahn, J; Jeong, M; Kang, S; Kim, S; Lee, E; Lee, I; Park, S; Seo, K, 2013) |
| "OBJECTIVE-To evaluate the mydriatic effect of intracameral injection of preservative-free 1% and 2% lidocaine hydrochloride solutions and determine the onset and duration of mydriasis according to the concentration and volume of lidocaine administered in healthy dogs." | 5.14 | Evaluation of the mydriatic effect of intracameral lidocaine hydrochloride injection in eyes of clinically normal dogs. ( Jeong, MB; Kim, NR; Kim, SE; Kim, TH; Kim, WT; Park, SA; Park, YW; Seo, KM, 2009) |
| "We evaluated, in a real-life setting, the effect of Mydrane® (ready-to-use combination of tropicamide, phenylephrine hydrochloride and lidocaine, injected into the anterior chamber at the beginning of cataract surgery to induce mydriasis and intraocular anaesthesia) on the pupil diameter during cataract surgery in patients with a preoperative pupil diameter <6 mm after the use of topical mydriatics." | 4.31 | Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm. ( Grabska-Liberek, I; Jurowski, P; Kęcik, D; Kopacz, D; Mianowska, K; Mrukwa-Kominek, E; Omulecki, W; Romaniuk, W; Romanowska-Dixon, B; Szaflik, J; Szaflik, JP, 2023) |
| "31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children." | 4.31 | Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023) |
| " Clinical features were hypotonia, pupillary mydriasis fixed to light, apnea, cyanosis and seizures." | 3.74 | [Lidocaine intoxication in newborn following maternal pudendal anesthesia: report of three cases]. ( de la Gastine, B; Guillemin, MG; Guillois, B; Lelong-Boulouard, V; Pagès, H; Quedru-Aboane, J, 2008) |
| "Mydrane is an effective and safe alternative to standard eye drops for initiating and maintaining intraoperative mydriasis and analgesia." | 2.82 | Evaluation of the efficacy and safety of a standardised intracameral combination of mydriatics and anaesthetics for cataract surgery. ( Alió, J; Behndig, A; Cochener, B; Colin, J; Findl, O; Hartani, D; Labetoulle, M; Lazreg, S; Lobo, C; Malecaze, F; Tassignon, MJ, 2016) |
| "Preoperative mydriasis is usually obtained by means of using combinations of sympatomimetics and parasympatolytics." | 1.35 | [Cataract surgery without preoperative mydriasis]. ( Maresová, K; Procházková, J, 2009) |
| "Unilateral mydriasis is a disturbing finding during anaesthesia and may indicate serious neurological injury." | 1.29 | Unilateral mydriasis after induction of anaesthesia. ( Prielipp, RC, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 4 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kęcik, D | 1 |
| Grabska-Liberek, I | 1 |
| Jurowski, P | 1 |
| Mrukwa-Kominek, E | 1 |
| Omulecki, W | 1 |
| Romanowska-Dixon, B | 1 |
| Szaflik, JP | 1 |
| Romaniuk, W | 1 |
| Szaflik, J | 1 |
| Kopacz, D | 1 |
| Mianowska, K | 1 |
| Nucci, P | 1 |
| Lembo, A | 1 |
| Caputo, R | 1 |
| Dellavalle, A | 1 |
| Serafino, M | 1 |
| Schiavetti, I | 1 |
| Pichi, F | 1 |
| Bhat, KT | 1 |
| Wadgaonkar, SP | 1 |
| Undre, AA | 1 |
| Heda, AS | 1 |
| Simons, RWP | 1 |
| Rondas, LUE | 1 |
| van den Biggelaar, FJHM | 1 |
| Berendschot, TTJM | 1 |
| Visser, N | 1 |
| de Crom, RMPC | 1 |
| Nuijts, RMMA | 2 |
| Mencucci, R | 1 |
| Viaud-Quentric, K | 1 |
| Elena, PP | 1 |
| Olmière, C | 1 |
| Behndig, A | 2 |
| Lay Suan, AL | 1 |
| Hamzah, JC | 1 |
| Ken, TS | 1 |
| Mansurali, VN | 1 |
| Davey, K | 1 |
| Chang, B | 1 |
| Purslow, C | 1 |
| Clay, E | 1 |
| Vataire, AL | 1 |
| Ahn, J | 1 |
| Jeong, M | 1 |
| Lee, E | 1 |
| Kim, S | 1 |
| Park, S | 2 |
| Kang, S | 1 |
| Lee, I | 1 |
| Seo, K | 1 |
| Labetoulle, M | 1 |
| Findl, O | 1 |
| Malecaze, F | 1 |
| Alió, J | 1 |
| Cochener, B | 1 |
| Lobo, C | 1 |
| Lazreg, S | 1 |
| Hartani, D | 1 |
| Colin, J | 1 |
| Tassignon, MJ | 1 |
| Jindal, M | 1 |
| Sharma, N | 1 |
| Parekh, N | 1 |
| Maresová, K | 1 |
| Procházková, J | 1 |
| Park, SA | 1 |
| Kim, NR | 1 |
| Park, YW | 1 |
| Jeong, MB | 1 |
| Kim, WT | 1 |
| Kim, SE | 1 |
| Kim, TH | 1 |
| Seo, KM | 1 |
| Williams, JV | 1 |
| Williams, LR | 1 |
| Colbert, SD | 1 |
| Revington, PJ | 1 |
| Berger, I | 1 |
| Steinberg, A | 1 |
| Schlesinger, Y | 1 |
| Seelenfreund, M | 1 |
| Schimmel, MS | 1 |
| Pagès, H | 1 |
| de la Gastine, B | 1 |
| Quedru-Aboane, J | 1 |
| Guillemin, MG | 1 |
| Lelong-Boulouard, V | 1 |
| Guillois, B | 1 |
| Prielipp, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery Versus Reference Group (Topical Mydriatics and Anaesthetic)[NCT02101359] | Phase 3 | 609 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02101359)
Timeframe: Day 0
| Intervention | percentage of responders (Number) |
|---|---|
| T2380 | 98.9 |
| Reference Group | 94.7 |
1 review available for lidocaine and Mydriasis
| Article | Year |
|---|---|
Amaurosis, ophthalmoplegia, ptosis, mydriasis and periorbital blanching following inferior alveolar nerve anaesthesia.
Topics: Adult; Amaurosis Fugax; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Blepharoptosis; | 2011 |
4 trials available for lidocaine and Mydriasis
| Article | Year |
|---|---|
Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study.
Topics: Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Phacoemulsification; Phenylephrine; Prospective | 2022 |
Effects of peribulbar anesthesia (sub-Tenon injection of a local anesthetic) on akinesia of extraocular muscles, mydriasis, and intraoperative and postoperative analgesia in dogs undergoing phacoemulsification.
Topics: Analgesia; Anesthesia, Local; Animals; Dog Diseases; Dogs; Drug Administration Routes; Female; Lidoc | 2013 |
Evaluation of the efficacy and safety of a standardised intracameral combination of mydriatics and anaesthetics for cataract surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dose-Response Relationship, Drug; Drug Therapy, | 2016 |
Evaluation of the mydriatic effect of intracameral lidocaine hydrochloride injection in eyes of clinically normal dogs.
Topics: Animals; Cross-Over Studies; Dogs; Dose-Response Relationship, Drug; Female; Lidocaine; Male; Mydria | 2009 |
11 other studies available for lidocaine and Mydriasis
| Article | Year |
|---|---|
Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm.
Topics: Anesthetics; Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmic Solutions; Phacoemulsifi | 2023 |
Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery.
Topics: Adult; Cataract; Child; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmology; Phacoemulsification | 2023 |
Cost analysis of mydriasis strategies in cataract surgery care in the Netherlands.
Topics: Cataract; Costs and Cost Analysis; Humans; Lidocaine; Mydriasis; Mydriatics; Netherlands; Phacoemuls | 2021 |
Ocular tolerance in rabbits after intracameral administration of a fixed combination of tropicamide, phenylephrine, and lidocaine with and without rinsing.
Topics: Animals; Endothelium, Corneal; Lidocaine; Mydriasis; Mydriatics; Phenylephrine; Pupil; Rabbits; Trop | 2017 |
Intracameral mydriatics versus topical mydriatics in pupil dilation for phacoemulsification cataract surgery.
Topics: Capsulorhexis; Cataract Extraction; Dilatation; Humans; Injections; Lens, Crystalline; Lidocaine; My | 2017 |
Budget impact model of Mydrane®, a new intracameral injectable used for intra-operative mydriasis, from a UK hospital perspective.
Topics: Anesthetics, Local; Budgets; Cost-Benefit Analysis; Drug Costs; Hospital Costs; Humans; Lidocaine; M | 2018 |
Intraoperative dilated pupil during nasal polypectomy.
Topics: Anesthetics, Local; Drug Combinations; Endoscopy; Humans; Intraoperative Complications; Lidocaine; M | 2009 |
[Cataract surgery without preoperative mydriasis].
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Mydriasis | 2009 |
Neonatal mydriasis: intravenous lidocaine adverse reaction.
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Drug Therapy, Combi | 2002 |
[Lidocaine intoxication in newborn following maternal pudendal anesthesia: report of three cases].
Topics: Anesthesia, Obstetrical; Anesthetics, Local; Apnea; Female; Humans; Infant, Newborn; Lidocaine; Male | 2008 |
Unilateral mydriasis after induction of anaesthesia.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Local; Female; Frail Elderly; Hum | 1994 |