Page last updated: 2024-10-28

lidocaine and Muscle Disorders

lidocaine has been researched along with Muscle Disorders in 20 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes."9.08The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995)
"To determine the attenuation in the incidence of myalgia, fasciculations and changes in serum potassium and creatinine kinase concentrations when atracurium and lidocaine were used in combination and separately as pretreatment before succinylcholine."9.08Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment. ( Raman, SK; San, WM, 1997)
"All RCTs and quasi-RCTs reporting use of cyclobenzaprine for treating MP with pain assessment as a primary or secondary outcome."8.85Cyclobenzaprine for the treatment of myofascial pain in adults. ( Andriolo, RB; Atallah, AN; da Silva, EM; El Dib, R; Grossmann, E; Januzzi, E; Leite, FM, 2009)
"Lidocaine attenuated hyperoxia-induced diaphragmatic dysfunction assessed by contractile profiles and fatigability in hamsters."7.70Attenuation of hyperoxia-induced diaphragmatic dysfunction with lidocaine in hamsters. ( Kagawa, T; Kodama, S; Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 2000)
"Epinephrine significantly increases lidocaine-induced skeletal muscle necrosis, even in low concentrations that elicit no damage by themselves."7.66Mechanism of epinephrine enhancement of lidocaine-induced skeletal muscle necrosis. ( Benoit, PW; Fort, NF; Yagiela, JA, 1982)
"In controls, the incidence of fasciculation was 95%, and the incidence of myalgia at 24 h was 50%."6.43Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. ( Fuchs-Buder, T; Lysakowski, C; Schreiber, JU; Tramèr, MR, 2005)
"To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes."5.08The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995)
"To determine the attenuation in the incidence of myalgia, fasciculations and changes in serum potassium and creatinine kinase concentrations when atracurium and lidocaine were used in combination and separately as pretreatment before succinylcholine."5.08Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment. ( Raman, SK; San, WM, 1997)
"All RCTs and quasi-RCTs reporting use of cyclobenzaprine for treating MP with pain assessment as a primary or secondary outcome."4.85Cyclobenzaprine for the treatment of myofascial pain in adults. ( Andriolo, RB; Atallah, AN; da Silva, EM; El Dib, R; Grossmann, E; Januzzi, E; Leite, FM, 2009)
"Lidocaine attenuated hyperoxia-induced diaphragmatic dysfunction assessed by contractile profiles and fatigability in hamsters."3.70Attenuation of hyperoxia-induced diaphragmatic dysfunction with lidocaine in hamsters. ( Kagawa, T; Kodama, S; Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 2000)
"Epinephrine significantly increases lidocaine-induced skeletal muscle necrosis, even in low concentrations that elicit no damage by themselves."3.66Mechanism of epinephrine enhancement of lidocaine-induced skeletal muscle necrosis. ( Benoit, PW; Fort, NF; Yagiela, JA, 1982)
"The results indicate that muscle fasciculation was not found in Group PR while the patients in Group LS had a lower incidence of muscle fasciculation than those in Group PS (p < 0."2.70Can lidocaine reduce succinylcholine induced postoperative myalgia? ( Amornyotin, S; Nilsuwankosit, P; Pipatnaraphong, H; Rachatamukayanant, P; Santawat, U, 2002)
"In controls, the incidence of fasciculation was 95%, and the incidence of myalgia at 24 h was 50%."2.43Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. ( Fuchs-Buder, T; Lysakowski, C; Schreiber, JU; Tramèr, MR, 2005)
"The evolution of diplopia decided the therapeutic attitude."1.35[Diplopia through toxic myopathy after cataract surgery]. ( Ciuică, M; Sevan, S; Vlăduţiu, C, 2008)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199010 (50.00)18.7374
1990's2 (10.00)18.2507
2000's8 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ochosi, K1
Vlăduţiu, C1
Sevan, S1
Ciuică, M1
Leite, FM1
Atallah, AN1
El Dib, R1
Grossmann, E1
Januzzi, E1
Andriolo, RB1
da Silva, EM1
Amornyotin, S1
Santawat, U1
Rachatamukayanant, P1
Nilsuwankosit, P1
Pipatnaraphong, H1
LAURENT, G1
GALLETTI, R1
PROCACCI, P1
MARCHETTI, PG1
ROCCHI, P1
BUZZELLI, G1
Schreiber, JU1
Lysakowski, C1
Fuchs-Buder, T1
Tramèr, MR1
Chatterji, S1
Thind, SS1
Daga, SR1
Gross, SG1
Yagiela, JA1
Benoit, PW1
Fort, NF1
Scudds, RA1
Janzen, V1
Delaney, G1
Heck, C1
McCain, GA1
Russell, AL1
Teasell, RW1
Varkey, G1
Woodbury, GM1
Raman, SK1
San, WM1
Nishina, K1
Mikawa, K1
Shiga, M1
Kodama, S1
Kagawa, T1
Maekawa, N1
Obara, H1
Mikat-Stevens, M1
Sukhani, R1
Pappas, AL1
Fluder, E1
Kleinman, B1
Stevens, RA1
Simon, E1
Matee, M1
Melnick, B1
Chalasani, J1
Uy, NT1
Phitayakorn, P1
Mallett, SV1
Rudy, TE1
Laurence, AS1
Le Lourd, R1
Le Lourd, F1
Tenser, RB1
Corbett, JJ1
Rondot, P1
Korn, H1
Scherrer, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Precurarization With Rocuronium on the Incidence and Severity of Succinylcholine-Induced Fasciculations and Myalgias in a High Volume ERCP Center[NCT04581395]Phase 3300 participants (Actual)Interventional2020-10-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for lidocaine and Muscle Disorders

ArticleYear
Cyclobenzaprine for the treatment of myofascial pain in adults.
    The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3

    Topics: Adult; Amitriptyline; Anesthetics, Local; Clonazepam; Fascia; Humans; Lidocaine; Muscle Relaxants, C

2009
Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials.
    Anesthesiology, 2005, Volume: 103, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fasciculation; Humans; Li

2005

Trials

5 trials available for lidocaine and Muscle Disorders

ArticleYear
Can lidocaine reduce succinylcholine induced postoperative myalgia?
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, Volume: 85 Suppl 3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Androstanols; Anesthetics, Local; Chi-Square Distribu

2002
The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial.
    Pain, 1995, Volume: 62, Issue:1

    Topics: Administration, Topical; Adult; Anxiety; Autonomic Nerve Block; Chronic Disease; Depression; Double-

1995
Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:5 Pt 1

    Topics: Adult; Atracurium; Creatine Kinase; Double-Blind Method; Fasciculation; Female; Humans; Lidocaine; M

1997
Is succinylcholine after pretreatment with d-tubocurarine and lidocaine contraindicated for outpatient anesthesia?
    Anesthesia and analgesia, 2000, Volume: 91, Issue:2

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthetics, Local; Contraindicat

2000
Decreasing post-succinylcholine myalgia in outpatients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1987, Volume: 34, Issue:3 ( Pt 1)

    Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Lidocaine; Muscular Dise

1987

Other Studies

13 other studies available for lidocaine and Muscle Disorders

ArticleYear
Rotator cuff disease. Simultaneous lidocaine may have confounded results.
    BMJ (Clinical research ed.), 2009, Feb-17, Volume: 338

    Topics: Anesthetics, Local; Humans; Injections, Intralesional; Lidocaine; Muscular Diseases; Rotator Cuff

2009
[Diplopia through toxic myopathy after cataract surgery].
    Oftalmologia (Bucharest, Romania : 1990), 2008, Volume: 52, Issue:4

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Diplopia; Eyeglasses; Female; Huma

2008
[RESULTS OF A MEDICAL TREATMENT OF MUSCULAR DYSTONY ACCOMPANYING COXARTHROSIS].
    Maroc medical, 1964, Volume: 43

    Topics: Anesthetics; Anesthetics, Local; Hip; Humans; Lidocaine; Muscular Diseases; Osteoarthritis; Osteoart

1964
[EXPLORATION OF THE SENSORY FUNCTION OF THE UPPER LIMB AND OF THE CORRELATED CUTANEOUS PHENOMENA IN FIBROMYALGIAS. EFFECTS OF BLOCKING OF THE SENSORY PATHWAYS AND STELLATE GANGLION].
    Archivio di fisiologia, 1963, Dec-30, Volume: 62

    Topics: Arm; Autonomic Nerve Block; Electrophysiology; Fibromyalgia; Humans; Lidocaine; Muscular Diseases; P

1963
Lignocaine pretreatment for suxamethonium. A clinicobiochemical study.
    Anaesthesia, 1983, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Calcium; Female; Humans; Lidocaine; Male; Middle Aged; Muscular Diseases; Pain, P

1983
More on neck pain.
    Headache, 1983, Volume: 23, Issue:4

    Topics: Carotid Artery Diseases; Diagnosis, Differential; Humans; Lidocaine; Muscular Diseases; Neck; Pain

1983
Mechanism of epinephrine enhancement of lidocaine-induced skeletal muscle necrosis.
    Journal of dental research, 1982, Volume: 61, Issue:5

    Topics: Animals; Drug Synergism; Epinephrine; Lidocaine; Male; Muscular Diseases; Necrosis; Phenylephrine; R

1982
Attenuation of hyperoxia-induced diaphragmatic dysfunction with lidocaine in hamsters.
    Critical care medicine, 2000, Volume: 28, Issue:6

    Topics: Animals; Cricetinae; Diaphragm; Hyperoxia; In Vitro Techniques; Lidocaine; Male; Muscular Diseases;

2000
Post-extraction complications seen at a referral dental clinic in Dar Es Salaam, Tanzania.
    International dental journal, 2001, Volume: 51, Issue:4

    Topics: Abscess; Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Local;

2001
Myalgia and biochemical changes following intermittent suxamethonium administration. Effects of alcuronium, lignocaine, midazolam and suxamethonium pretreatments on serum myoglobin, creatinine kinase and myalgia.
    Anaesthesia, 1987, Volume: 42, Issue:5

    Topics: Adult; Alcuronium; Creatine Kinase; Female; Humans; Lidocaine; Midazolam; Muscular Diseases; Myoglob

1987
[Thoracic pains. Rhomboideus "pedicle" syndrome].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Jan-26, Volume: 49, Issue:5

    Topics: Humans; Injections; Lidocaine; Muscular Diseases; Pain; Shoulder; Spine; Tendons; Thoracic Vertebrae

1973
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F

1974
[Induction at a distance of tremorigenic rhythms from a single muscular group].
    Revue neurologique, 1966, Volume: 115, Issue:5

    Topics: Adolescent; Electromyography; Humans; Lidocaine; Male; Movement Disorders; Muscles; Muscular Disease

1966