Page last updated: 2024-10-28

lidocaine and Multiple Sclerosis

lidocaine has been researched along with Multiple Sclerosis in 10 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Research Excerpts

ExcerptRelevanceReference
"5 to 2-microliters injections of 2% lidocaine at appropriate sites in the thalamic ventrocaudal or ventrointermedius nucleus can produce a temporary marked suppression of tremor."3.68Microinjection of lidocaine into human thalamus: a useful tool in stereotactic surgery. ( Davis, KD; Dostrovsky, JO; Hutchison, WD; Parrent, AG; Sher, GD; Tasker, RR, 1993)
"To lower postoperative pain and the inflammatory response we have administered successfully intravenous lidocaine, indicating that it is possible to avoid regional anesthesia in patients with multiple sclerosis scheduled for mini-invasive left ventricular reconstruction requiring a mini-thoracotomy."1.43Perioperative management of a patient undergoing a novel mini-invasive percutaneous transcatheter left ventricular reconstruction procedure. ( Cornolle, C; Labrousse, L; Ouattara, A; Zaouter, C, 2016)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ekiz, T1
Mezian, K1
Zaouter, C1
Cornolle, C1
Labrousse, L1
Ouattara, A1
Tamam, Y1
Özdemir, HH1
Gedik, A1
Tamam, C1
Nazlıkul, H1
GEJROT, T1
Dostrovsky, JO1
Sher, GD1
Davis, KD1
Parrent, AG1
Hutchison, WD1
Tasker, RR1
Sakurai, M2
Kanazawa, I2
Mannen, T1
Tanabe, H1
Albrecht, D1
Nagel, R1
Kölln, CP1
Rockswold, GL2
Bradley, WE2
Chou, SN2

Trials

1 trial available for lidocaine and Multiple Sclerosis

ArticleYear
Positive symptoms in multiple sclerosis: their treatment with sodium channel blockers, lidocaine and mexiletine.
    Journal of the neurological sciences, 1999, Jan-15, Volume: 162, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; M

1999

Other Studies

9 other studies available for lidocaine and Multiple Sclerosis

ArticleYear
Neural or "Moral" therapy in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients.
    Neurourology and urodynamics, 2018, Volume: 37, Issue:8

    Topics: Humans; Lidocaine; Morals; Multiple Sclerosis; Urinary Bladder, Neurogenic

2018
Perioperative management of a patient undergoing a novel mini-invasive percutaneous transcatheter left ventricular reconstruction procedure.
    Journal of clinical anesthesia, 2016, Volume: 32

    Topics: Anesthetics, Local; Echocardiography, Three-Dimensional; Heart Failure; Heart Ventricles; Humans; Li

2016
Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients.
    Neurourology and urodynamics, 2017, Volume: 36, Issue:7

    Topics: Adult; Anesthetics, Local; Female; Humans; Injections, Epidural; Injections, Intradermal; Lidocaine;

2017
THE INFLUENCE OF XYLOCAINE ON INDUCED AND SPONTANEOUS NYSTAGMUS. A PRELIMINARY REPORT.
    Practica oto-rhino-laryngologica, 1963, Volume: 25

    Topics: Alcoholism; Amyotrophic Lateral Sclerosis; Brain Neoplasms; Dimenhydrinate; Epilepsy; Lidocaine; Men

1963
Microinjection of lidocaine into human thalamus: a useful tool in stereotactic surgery.
    Stereotactic and functional neurosurgery, 1993, Volume: 60, Issue:4

    Topics: Electric Stimulation; Electrocoagulation; Humans; Lidocaine; Microinjections; Multiple Sclerosis; Pa

1993
Lidocaine unmasks silent demyelinative lesions in multiple sclerosis.
    Neurology, 1992, Volume: 42, Issue:11

    Topics: Adult; Evoked Potentials, Visual; Female; Humans; Lidocaine; Male; Middle Aged; Multiple Sclerosis;

1992
Electrohydraulic waves (Urat I) for the treatment of vesical calculi.
    International urology and nephrology, 1972, Volume: 4, Issue:1

    Topics: Aged; Anesthesia, Endotracheal; Anesthesia, Local; Anesthesia, Spinal; Biguanides; Calcium; Drug Com

1972
Differential sacral rhizotomy in the treatment of neurogenic bladder dysfunction. Preliminary report of six cases.
    Journal of neurosurgery, 1973, Volume: 38, Issue:6

    Topics: Adult; Electric Stimulation; Electromyography; Evaluation Studies as Topic; Female; Humans; Lidocain

1973
Effect of sacral nerve blocks on the function of the urinary bladder in humans.
    Journal of neurosurgery, 1974, Volume: 40, Issue:1

    Topics: Diabetes Mellitus; Humans; Lidocaine; Lumbosacral Plexus; Multiple Sclerosis; Nerve Block; Pain; Par

1974