lidocaine has been researched along with Multiple Organ Failure in 5 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prognostic value of a dynamic liver-function test, based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX), in predicting multiple organ failure (MOF) was prospectively investigated in 28 critically ill patients after multiple trauma." | 7.69 | Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure. ( Armstrong, VW; Lehmann, U; Oellerich, M; Pape, D; Regel, G; Schütz, E, 1995) |
| "The goal of this prospective, randomised, double-blind clinical trial study was to assess the effects of dopexamine hydrochloride on organ failure, inflammatory mediators and splanchnic oxygenation in blunt multiple trauma patients at high risk of multiple organ dysfunction syndrome (MODS)." | 5.14 | Is dopexamine superior to dopamine in the treatment of multiple trauma patients--a prospective, double-blind, randomised study. ( Baur, H; Grotz, MR; Hildebrand, F; Krettek, C; Mahlke, L; Pape, HC; Probst, C; van Griensven, M, 2010) |
| "The prognostic value of a dynamic liver-function test, based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX), in predicting multiple organ failure (MOF) was prospectively investigated in 28 critically ill patients after multiple trauma." | 3.69 | Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure. ( Armstrong, VW; Lehmann, U; Oellerich, M; Pape, D; Regel, G; Schütz, E, 1995) |
| "The prognostic value of a dynamic liver-function test, based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX), in predicting multiple organ failure (MOF) was prospectively investigated in 28 critically ill patients after multiple trauma." | 3.69 | [Multiple organ failure after severe trauma: predictable by the MEGX liver function test?]. ( Lehmann, U; Oellerich, M; Pape, D; Regel, G, 1996) |
| "Four patients developed multiple organ failure (MOF)." | 1.28 | Plasma lignocaine concentrations associated with extradural analgesia in patients with and without multiple organ failure. ( Herold, M; Lingnau, W; Putensen, C; Putensen-Himmer, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Probst, C | 1 |
| Hildebrand, F | 1 |
| van Griensven, M | 1 |
| Baur, H | 1 |
| Mahlke, L | 1 |
| Krettek, C | 1 |
| Pape, HC | 1 |
| Grotz, MR | 1 |
| Maynard, ND | 1 |
| Bihari, DJ | 1 |
| Dalton, RN | 1 |
| Smithies, MN | 1 |
| Mason, RC | 1 |
| Lehmann, U | 2 |
| Armstrong, VW | 1 |
| Schütz, E | 1 |
| Regel, G | 2 |
| Pape, D | 2 |
| Oellerich, M | 2 |
| Putensen, C | 1 |
| Lingnau, W | 1 |
| Putensen-Himmer, G | 1 |
| Herold, M | 1 |
2 trials available for lidocaine and Multiple Organ Failure
| Article | Year |
|---|---|
Is dopexamine superior to dopamine in the treatment of multiple trauma patients--a prospective, double-blind, randomised study.
Topics: Adolescent; Adult; Blood Pressure; Critical Care; Dopamine; Double-Blind Method; Female; Gastric Muc | 2010 |
Increasing splanchnic blood flow in the critically III.
Topics: Adult; Aged; Anesthetics, Local; Coloring Agents; Critical Illness; Dopamine; Dopamine Agonists; Gas | 1995 |
3 other studies available for lidocaine and Multiple Organ Failure
| Article | Year |
|---|---|
Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure.
Topics: Adult; Aged; Bilirubin; Diagnosis, Differential; Female; Humans; Lidocaine; Liver Function Tests; Ma | 1995 |
[Multiple organ failure after severe trauma: predictable by the MEGX liver function test?].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Critical Care; Humans; Injury Severity Score; Lid | 1996 |
Plasma lignocaine concentrations associated with extradural analgesia in patients with and without multiple organ failure.
Topics: Adult; Analgesia, Epidural; Critical Care; Female; Humans; Infusions, Parenteral; Lidocaine; Male; M | 1992 |