lidocaine has been researched along with Motor Neuron Disease in 2 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine was microinjected in the RVM or PAG and allodynia was quantitatively determined by measuring the hindlimb withdrawal thresholds to mechanical stimulation of the paw." | 1.29 | Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats. ( Hämäläinen, MM; Pertovaara, A; Wei, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niyogi, S | 1 |
| Mukherjee, D | 1 |
| Chakraborty, J | 1 |
| Mitra, P | 1 |
| Santra, S | 1 |
| Acharya, A | 1 |
| Pertovaara, A | 1 |
| Wei, H | 1 |
| Hämäläinen, MM | 1 |
2 other studies available for lidocaine and Motor Neuron Disease
| Article | Year |
|---|---|
Anaesthetic management of a patient with motor neuron disease posted for microlaryngeal surgery.
Topics: Anesthesia, General; Contraindications; Female; Humans; Intubation, Intratracheal; Laryngeal Disease | 2012 |
Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Lidocaine; Male; Medulla Oblongat | 1996 |