Page last updated: 2024-10-28

lidocaine and Lymph Node Metastasis

lidocaine has been researched along with Lymph Node Metastasis in 4 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Between January 2006 and April 2009, 140 patients with early breast cancer were randomly assigned (1:1:1:1) to receive standard topical 4 % lidocaine cream and intradermal Tc-99m (control) or to one of three other study groups: topical placebo cream and injection of Tc-99m containing sodium bicarbonate (NaHCO3), 1 % lidocaine, or both."9.17Technical effects of adding 1 % lidocaine to technetium sulfur colloid for sentinel lymphatic mapping in early breast cancer: analysis of data from a double-blind randomized controlled trial. ( Arciero, CA; Avital, I; Bilchik, AJ; Buckenmaier Iii, CC; Henry, LR; Howard, RS; Peoples, GE; Stojadinovic, A, 2013)
"Between January 2006 and April 2009, 140 patients with early breast cancer were randomly assigned (1:1:1:1) to receive standard topical 4 % lidocaine cream and intradermal Tc-99m (control) or to one of three other study groups: topical placebo cream and injection of Tc-99m containing sodium bicarbonate (NaHCO3), 1 % lidocaine, or both."5.17Technical effects of adding 1 % lidocaine to technetium sulfur colloid for sentinel lymphatic mapping in early breast cancer: analysis of data from a double-blind randomized controlled trial. ( Arciero, CA; Avital, I; Bilchik, AJ; Buckenmaier Iii, CC; Henry, LR; Howard, RS; Peoples, GE; Stojadinovic, A, 2013)
" The purpose of this study was to evaluate efficacy of lidocaine/prilocaine cream in decreasing the pain of injection for sentinel lymph node biopsy."5.15Do topical anesthetics reduce periareolar injectional pain before sentinel lymph node biopsy? ( Cusick, TE; Helmer, SD; O'Connor, JM; Osland, JS; Tenofsky, PL, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arciero, CA1
Henry, LR1
Howard, RS1
Peoples, GE1
Bilchik, AJ1
Avital, I1
Buckenmaier Iii, CC1
Stojadinovic, A1
Fetzer, S1
Holmes, S1
O'Connor, JM1
Helmer, SD1
Osland, JS1
Cusick, TE1
Tenofsky, PL1
Topar, G1
Zelger, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Alkalinization of Technetium-99m Sulfur Colloid Reduce Perceived Pain Levels During Non-breast Sentinel Lymphoscintigraphy?[NCT01660412]60 participants (Actual)Interventional2012-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Perceived Pain Level

Immediately after receiving an injection, subjects will rate their perceived pain level, using a validated measure. Subject was asked to quantify the pain of every injection using a validated scale from 0 through 10, with 0 being no pain and 10 being severe pain that is disabling. The effect of treatment was estimated by taking the difference of the mean buffered and SOC pain scores and a paired t-test was used to test whether the mean difference was significantly different from 0. Perceived pain levels assessed after each injection were averaged for each participant. (NCT01660412)
Timeframe: immediately after administration (<1 min) of each injection (up to total 5 minutes)

Interventionunits on a scale (Mean)
Standard of Care Injection5.81
PH Altered Injection4.39

Trials

2 trials available for lidocaine and Lymph Node Metastasis

ArticleYear
Technical effects of adding 1 % lidocaine to technetium sulfur colloid for sentinel lymphatic mapping in early breast cancer: analysis of data from a double-blind randomized controlled trial.
    Annals of surgical oncology, 2013, Volume: 20, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Breast Neoplasms; Double-Blind Method; Female; H

2013
Do topical anesthetics reduce periareolar injectional pain before sentinel lymph node biopsy?
    American journal of surgery, 2011, Volume: 202, Issue:6

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Breast Neoplasms; Double-

2011

Other Studies

2 other studies available for lidocaine and Lymph Node Metastasis

ArticleYear
Relieving the pain of sentinel lymph node biopsy tracer injection.
    Clinical journal of oncology nursing, 2008, Volume: 12, Issue:4

    Topics: Administration, Cutaneous; Anesthetics, Combined; Anesthetics, Local; Breast Neoplasms; Clinical Nur

2008
Assessment of value of the sentinel lymph node biopsy in melanoma in children and adolescents and applicability of subcutaneous infusion anesthesia.
    Journal of pediatric surgery, 2007, Volume: 42, Issue:10

    Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Child; Colloids; Coloring Agents; Female;

2007