lidocaine has been researched along with Lung Neoplasms in 37 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a 4T1 murine model of breast cancer surgery, under sevoflurane anaesthesia, lidocaine enhanced the metastasis-inhibiting action of cisplatin." | 7.88 | Effect of Perioperative Lidocaine and Cisplatin on Metastasis in a Murine Model of Breast Cancer Surgery. ( Buggy, DJ; Crowley, PD; Foley, AG; Freeman, J; Gallagher, HC; Iwasaki, M; Ma, D, 2018) |
| "NCI-H838 lung adenocarcinoma cells were incubated with ropivacaine or lidocaine (1 nM-100 µM) in absence/presence of TNFα (20 ng ml(-1)) for 20 min or 4 h, respectively." | 7.81 | Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase. ( Beck-Schimmer, B; Borgeat, A; Dull, RO; Minshall, RD; Piegeler, T; Schläpfer, M; Schwartz, DE, 2015) |
| "A patient twice developed the adult respiratory distress syndrome following an adverse reaction to administration of lidocaine." | 7.66 | Adult respiratory distress syndrome following administration of lidocaine. ( Howard, JJ; Mohsenifar, Z; Simons, SM, 1982) |
| "Cough is one of the most common symptoms prompting patients to be seen by health care providers in the United States." | 6.49 | Nebulized lidocaine in the treatment of intractable cough. ( Jurdi, A; Truesdale, K, 2013) |
| "In a 4T1 murine model of breast cancer surgery, under sevoflurane anaesthesia, lidocaine enhanced the metastasis-inhibiting action of cisplatin." | 3.88 | Effect of Perioperative Lidocaine and Cisplatin on Metastasis in a Murine Model of Breast Cancer Surgery. ( Buggy, DJ; Crowley, PD; Foley, AG; Freeman, J; Gallagher, HC; Iwasaki, M; Ma, D, 2018) |
| "Lidocaine is the most commonly used local anaesthetic in clinical and can inhibit proliferation, suppress invasion and migration and induce apoptosis in human lung adenocarcinoma (LAD) cells." | 3.85 | Lidocaine inhibits the proliferation of lung cancer by regulating the expression of GOLT1A. ( Cheng, Y; Hu, R; Jiang, H; Sun, Y; Wu, X; Xi, S; Zhang, L, 2017) |
| "NCI-H838 lung adenocarcinoma cells were incubated with ropivacaine or lidocaine (1 nM-100 µM) in absence/presence of TNFα (20 ng ml(-1)) for 20 min or 4 h, respectively." | 3.81 | Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase. ( Beck-Schimmer, B; Borgeat, A; Dull, RO; Minshall, RD; Piegeler, T; Schläpfer, M; Schwartz, DE, 2015) |
| "A patient twice developed the adult respiratory distress syndrome following an adverse reaction to administration of lidocaine." | 3.66 | Adult respiratory distress syndrome following administration of lidocaine. ( Howard, JJ; Mohsenifar, Z; Simons, SM, 1982) |
| "Cough is one of the most common symptoms prompting patients to be seen by health care providers in the United States." | 2.49 | Nebulized lidocaine in the treatment of intractable cough. ( Jurdi, A; Truesdale, K, 2013) |
| "Lidocaine is a local anesthetic that wildly used in surgical treatment and postoperative medical care for lung cancers." | 1.72 | Lidocaine inhibited migration of NSCLCA549 cells via the CXCR4 regulation. ( Cui, Y; Xing, B; Yang, L, 2022) |
| "Two patients had cardiac arrest before sclerosis could be attempted." | 1.29 | Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade. ( Maher, EA; Shepherd, FA; Todd, TJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (37.84) | 18.7374 |
| 1990's | 5 (13.51) | 18.2507 |
| 2000's | 4 (10.81) | 29.6817 |
| 2010's | 10 (27.03) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Balaban, O | 1 |
| Aydın, T | 1 |
| Yaman, M | 1 |
| Wang, L | 1 |
| Sun, J | 1 |
| Zhang, X | 1 |
| Wang, G | 1 |
| Xing, B | 1 |
| Yang, L | 1 |
| Cui, Y | 1 |
| Hou, YH | 1 |
| Shi, WC | 1 |
| Cai, S | 1 |
| Liu, H | 1 |
| Zheng, Z | 1 |
| Qi, FW | 1 |
| Li, C | 1 |
| Feng, XM | 1 |
| Peng, K | 1 |
| Ji, FH | 1 |
| Zhang, L | 1 |
| Hu, R | 1 |
| Cheng, Y | 1 |
| Wu, X | 1 |
| Xi, S | 1 |
| Sun, Y | 1 |
| Jiang, H | 1 |
| Johnson, MZ | 1 |
| Crowley, PD | 2 |
| Foley, AG | 2 |
| Xue, C | 1 |
| Connolly, C | 1 |
| Gallagher, HC | 2 |
| Buggy, DJ | 2 |
| Freeman, J | 1 |
| Iwasaki, M | 1 |
| Ma, D | 1 |
| Akkuş, M | 1 |
| Öner, E | 1 |
| Dong, Q | 1 |
| Mao, Z | 1 |
| Berna, C | 1 |
| Luthy, C | 1 |
| Samer, CF | 1 |
| Spechbach, H | 1 |
| Pautex, S | 1 |
| Piguet, V | 1 |
| Piegeler, T | 2 |
| Schläpfer, M | 1 |
| Dull, RO | 1 |
| Schwartz, DE | 2 |
| Borgeat, A | 2 |
| Minshall, RD | 2 |
| Beck-Schimmer, B | 2 |
| Kukkar, V | 1 |
| Miller, VA | 1 |
| Richardson, MA | 1 |
| Nerenz, RD | 1 |
| Votta-Velis, EG | 1 |
| Liu, G | 1 |
| Place, AT | 1 |
| Truesdale, K | 1 |
| Jurdi, A | 1 |
| Mammoto, T | 1 |
| Higashiyama, S | 1 |
| Mukai, M | 1 |
| Mammoto, A | 1 |
| Ayaki, M | 1 |
| Mashimo, T | 1 |
| Hayashi, Y | 1 |
| Kishi, Y | 1 |
| Nakamura, H | 1 |
| Akedo, H | 1 |
| Mercadante, S | 1 |
| Villari, P | 1 |
| Ferrera, P | 1 |
| Arcuri, E | 1 |
| HOLLING, HE | 1 |
| DANIELSON, GK | 1 |
| HAMILTON, RW | 1 |
| BLAKEMORE, WS | 1 |
| BRODEY, RS | 1 |
| EDMONDS-SEAL, J | 1 |
| Luketich, JD | 1 |
| Land, SR | 1 |
| Sullivan, EA | 1 |
| Alvelo-Rivera, M | 1 |
| Ward, J | 1 |
| Buenaventura, PO | 1 |
| Landreneau, RJ | 1 |
| Hart, LA | 1 |
| Fernando, HC | 1 |
| Howard, JJ | 1 |
| Mohsenifar, Z | 1 |
| Simons, SM | 1 |
| Fratacci, MD | 1 |
| Kimball, WR | 1 |
| Wain, JC | 1 |
| Kacmarek, RM | 1 |
| Polaner, DM | 1 |
| Zapol, WM | 1 |
| Maher, EA | 1 |
| Shepherd, FA | 1 |
| Todd, TJ | 1 |
| Nomori, H | 1 |
| Horio, H | 1 |
| Morinaga, S | 1 |
| Kobayashi, R | 1 |
| Fuyuno, G | 1 |
| Suemasu, K | 1 |
| Vermylen, P | 1 |
| Pierard, P | 1 |
| Roufosse, C | 1 |
| Bosschaerts, T | 1 |
| Verhest, A | 1 |
| Sculier, JP | 1 |
| Ninane, V | 1 |
| Illek, B | 1 |
| Lizarzaburu, ME | 1 |
| Lee, V | 1 |
| Nantz, MH | 1 |
| Kurth, MJ | 1 |
| Fischer, H | 1 |
| Due, J | 1 |
| Stewart, CJ | 1 |
| Coady, TJ | 1 |
| Patterson, JR | 1 |
| Blaschke, TF | 1 |
| Hunt, KK | 1 |
| Meffin, PJ | 1 |
| Kawamata, M | 1 |
| Omote, K | 1 |
| Namiki, A | 1 |
| Ameer, B | 1 |
| Burlingame, MB | 1 |
| Harman, EM | 1 |
| Duda, K | 1 |
| Kołodziejski, L | 1 |
| Kwiecień, G | 1 |
| Machowska, B | 1 |
| McLennan, G | 1 |
| Gill, PG | 1 |
| De Young, NJ | 1 |
| Kudo, T | 1 |
| Abo, S | 1 |
| Itabashi, T | 1 |
| Onodera, K | 1 |
| Shikama, T | 1 |
| Hashimoto, M | 1 |
| Kawamura, Y | 1 |
| Tsuji, K | 1 |
| Watanabe, K | 1 |
| Ikeda, T | 1 |
| Nelson, SW | 1 |
| Christoforidis, AJ | 1 |
| Janower, ML | 1 |
| Land, RE | 1 |
| Sanderson, DR | 1 |
| Dawson, B | 1 |
| Wang, JK | 1 |
| Kacki, J | 1 |
| Droszcz, W | 1 |
| Kamiński, B | 1 |
| Ajewski, Z | 1 |
| Koziorowski, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Perioperative Pain Management for Laparoscopic Surgery Due to Colon Cancer Using the Ultrasound-guided Transmuscular Quadratus Lumborum Block. A Double Blind, Randomized, Placebo Controlled Trial.[NCT03570541] | Phase 4 | 69 participants (Actual) | Interventional | 2018-06-28 | Completed | ||
| Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery[NCT03974984] | 0 participants (Actual) | Observational | 2020-06-04 | Withdrawn (stopped due to Not feasable due to logistics) | |||
| Effects of Epidural Anesthesia-analgesia on Long-term Survival in Patients After Lung Cancer Surgery: A Randomized Controlled Trial[NCT02801409] | 400 participants (Actual) | Interventional | 2015-05-25 | Completed | |||
| Liposomal Bupivacaine Versus Bupivacaine for Postoperative Analgesia Following Video-assisted Thoracoscopic Surgery.[NCT03036085] | Phase 2/Phase 3 | 200 participants (Anticipated) | Interventional | 2017-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lidocaine and Lung Neoplasms
| Article | Year |
|---|---|
Nebulized lidocaine in the treatment of intractable cough.
Topics: Administration, Inhalation; Anesthetics, Local; Cough; Humans; Lidocaine; Lung Neoplasms; Nebulizers | 2013 |
Lung biopsy. Bronchial brushing and percutaneous puncture.
Topics: Biopsy; Bronchi; Carcinoma, Squamous Cell; Catheterization; Cytodiagnosis; Humans; Lidocaine; Lung; | 1971 |
4 trials available for lidocaine and Lung Neoplasms
| Article | Year |
|---|---|
The Effect of Lidocaine on Postoperative Quality of Recovery and Lung Protection of Patients Undergoing Thoracoscopic Radical Resection of Lung Cancer.
Topics: Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Lung; Lung Neoplasms; Male; Midd | 2021 |
Effect of Intravenous Lidocaine on Serum Interleukin-17 After Video-Assisted Thoracic Surgery for Non-Small-Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adult; Anesthetics, Local; Carcinoma, Non-Small-Cell Lung; Double-Blind Method; Female; Follow-Up St | 2021 |
Thoracic epidural versus intercostal nerve catheter plus patient-controlled analgesia: a randomized study.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Anesthesia, Epidural; Anesthetics, Lo | 2005 |
Diaphragmatic shortening after thoracic surgery in humans. Effects of mechanical ventilation and thoracic epidural anesthesia.
Topics: Adenocarcinoma; Aged; Anesthesia, Epidural; Autonomic Nerve Block; Diaphragm; Female; Humans; Lidoca | 1993 |
31 other studies available for lidocaine and Lung Neoplasms
| Article | Year |
|---|---|
Ultrasound-guided erector spinae plane catheter placement for long-term continuous analgesia in pulmonary malignancy.
Topics: Aged; Anesthetics, Local; Catheters, Indwelling; Female; Humans; Lidocaine; Lung Neoplasms; Mesothel | 2019 |
Lidocaine inhibited migration of NSCLCA549 cells via the CXCR4 regulation.
Topics: Actins; Calcium; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation | 2022 |
Lidocaine inhibits the proliferation of lung cancer by regulating the expression of GOLT1A.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anesthetics, Local; Antineoplastic Agents; Cell Cycle; Cell | 2017 |
Effect of perioperative lidocaine on metastasis after sevoflurane or ketamine-xylazine anaesthesia for breast tumour resection in a murine model.
Topics: Adrenergic alpha-Agonists; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Local; A | 2018 |
Effect of Perioperative Lidocaine and Cisplatin on Metastasis in a Murine Model of Breast Cancer Surgery.
Topics: Anesthetics, Local; Animals; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Drug Therapy, Combi | 2018 |
Can local infiltration of lidocaine reduce the postoperative atrial fibrillation rate in patients undergoing lobectomy for lung cancer?
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Atrial Fibrillation; Carcinoma, Non-Small-Cell Lung; Fe | 2020 |
The Local Anaesthetic Lignocaine Exhibits Potent Antilung Cancer Cell Activity by Inhibiting the Phosphoinositide 3-Kinases/Mammalian Target of Rapamycin/Mammalian Target of Rapamycin Pathway.
Topics: Anesthetics, Local; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; | 2019 |
[Efficient treatment of breakthrough pain in adults: the importance of timing and medication choice].
Topics: Administration, Cutaneous; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammato | 2013 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
What's Wrong with These Pleural Fluid Samples?
Topics: Blood Gas Analysis; Humans; Hydrogen-Ion Concentration; Lidocaine; Lung Neoplasms; Male; Middle Aged | 2016 |
Antimetastatic potential of amide-linked local anesthetics: inhibition of lung adenocarcinoma cell migration and inflammatory Src signaling independent of sodium channel blockade.
Topics: Adenocarcinoma; Amides; Anesthetics, Local; Cell Line, Tumor; Cell Movement; Humans; Intercellular A | 2012 |
Infiltration anesthetic lidocaine inhibits cancer cell invasion by modulating ectodomain shedding of heparin-binding epidermal growth factor-like growth factor (HB-EGF).
Topics: Anesthetics, Local; Animals; Calcium; Cell Membrane; Cell Movement; Epidermal Growth Factor; ErbB Re | 2002 |
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
Topics: Adult; Anesthetics, Local; Bupivacaine; Carcinoma, Small Cell; Endometrial Neoplasms; Female; Humans | 2003 |
HYPERTROPHIC PULMONARY OSTEOARTHROPATHY.
Topics: Blood Circulation; Carcinoma; Carcinoma, Bronchogenic; Dog Diseases; Dogs; Lidocaine; Lung Neoplasms | 1963 |
AN OVERDOSE OF LIGNOCAINE. A CASE REPORT ON EPIDURAL ANALGESIA FOR POST-OPERATIVE PAIN.
Topics: Analgesia, Epidural; Anesthesia; Anesthesia, Spinal; Catheterization; Humans; Lidocaine; Lung Neopla | 1964 |
Adult respiratory distress syndrome following administration of lidocaine.
Topics: Adenocarcinoma; Female; Humans; Intubation, Intratracheal; Lidocaine; Lung Neoplasms; Middle Aged; R | 1982 |
Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade.
Topics: Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Arrhythmias, Cardiac; Bacterial Infections; | 1996 |
[Usefulness of marking with colored collagen to localize small pulmonary nodules for thoracoscopic biopsy].
Topics: Collagen; Coloring Agents; Female; Humans; Lidocaine; Lung Neoplasms; Male; Methylene Blue; Middle A | 1998 |
Detection of bronchial preneoplastic lesions and early lung cancer with fluorescence bronchoscopy: a study about its ambulatory feasibility under local anaesthesis.
Topics: Ambulatory Care; Anesthesia, Local; Anesthetics, Local; Biopsy; Bronchial Neoplasms; Bronchoscopy; C | 1999 |
Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenocarcinoma; Anesthetics, Local; Apigenin; Biol | 2000 |
[Easing of a painful death].
Topics: Adult; Aged; Celiac Plexus; Ethanol; Female; Humans; Injections, Spinal; Lidocaine; Lung Neoplasms; | 1977 |
Suppression of intractable cough.
Topics: Aerosols; Cough; Humans; Lidocaine; Lung Neoplasms | 1977 |
Lidocaine blood concentrations during fiberoptic bronchoscopy.
Topics: Absorption; Adult; Bronchi; Bronchitis; Bronchoscopy; Female; Fiber Optic Technology; Humans; Lidoca | 1975 |
Bilateral interpleural injection of lidocaine after bilateral lung surgery through median sternotomy in four patients.
Topics: Adolescent; Adult; Aged; Blister; Female; Humans; Lidocaine; Lung Diseases; Lung Neoplasms; Male; Mi | 1992 |
Rapid mucosal absorption of topical lidocaine during bronchoscopy in the presence of oral candidiasis.
Topics: Absorption; Adenocarcinoma; Administration, Topical; Bronchoscopy; Candidiasis, Oral; Humans; Lidoca | 1989 |
[Effect of cachexia and intravenously administered lidocaine on the hemodynamic reaction during bronchoscopy].
Topics: Adult; Aged; Anesthesia, Intravenous; Bronchoscopy; Cachexia; Hemodynamics; Humans; Lidocaine; Lung | 1987 |
Antibody-dependent cellular cytotoxicity in blood monocytes and alveolar macrophages in patients with lung cancer.
Topics: Aged; Antibody-Dependent Cell Cytotoxicity; Female; Humans; Immunologic Deficiency Syndromes; Lidoca | 1985 |
[Enhancing activity of bacterial preparations on blood flow in tumor tissue, with reference to cancer chemotherapy. Experimental and clinical studies].
Topics: Adult; Aged; Animals; Biological Products; Blood Volume; Breast Neoplasms; Esophageal Neoplasms; Fem | 1985 |
Bronchography in diseases of the adult chest.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Adult; Bronchial Diseases; Bronchiectasis; Bronchitis; | 1973 |
Bronchospirometry during diagnostic bronchoscopy.
Topics: Adult; Aged; Atropine; Bronchoscopy; Bronchospirometry; Female; Humans; Lidocaine; Lung Diseases; Lu | 1971 |
Comparative studies on bronchospirometry under general and local anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Bronchiectasis; Bronchospirometry; | 1968 |