lidocaine has been researched along with Lung Injury, Acute in 6 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine (Lido) is reported to suppress inflammatory responses and exhibit a therapeutic effect in models of cecal ligation and puncture (CLP)-induced acute lung injury (ALI)." | 7.85 | RAGE deficiency attenuates the protective effect of Lidocaine against sepsis-induced acute lung injury. ( Jiang, X; Li, X; Liao, C; Liu, M; Song, D; Zhang, Z; Zhou, J, 2017) |
| "Acute lung injury is a severe disease with a high rate of mortality, leading to more important illness." | 5.48 | The protective effect of lidocaine on lipopolysaccharide-induced acute lung injury in rats through NF-κB and p38 MAPK signaling pathway and excessive inflammatory responses. ( Chen, LJ; Ding, YB; Du, J; Jiang, SH; Li, AZ; Li, KZ; Li, MC; Ma, PL; Shi, CX; Zhou, HD, 2018) |
| " Instead of using deep sedation and neuromuscular blockade, the authors hypothesized that perineural administration of lidocaine around the phrenic nerve would reduce tidal volume (VT) and peak transpulmonary pressure in spontaneously breathing patients with acute respiratory distress syndrome." | 4.12 | Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury. ( Adkson Sales Lima, C; Amato, MBP; Brochard, L; Costa, ELV; Goligher, EC; Ho, YL; Morais, CCA; Nakamura, MAM; Pereira, SM; Ranzani, OT; Sinedino, BE; Sklar, MC; Taniguchi, LU; Tucci, MR; Vieira, JE, 2022) |
| "Lidocaine (Lido) is reported to suppress inflammatory responses and exhibit a therapeutic effect in models of cecal ligation and puncture (CLP)-induced acute lung injury (ALI)." | 3.85 | RAGE deficiency attenuates the protective effect of Lidocaine against sepsis-induced acute lung injury. ( Jiang, X; Li, X; Liao, C; Liu, M; Song, D; Zhang, Z; Zhou, J, 2017) |
| "Acute lung injury is a severe disease with a high rate of mortality, leading to more important illness." | 1.48 | The protective effect of lidocaine on lipopolysaccharide-induced acute lung injury in rats through NF-κB and p38 MAPK signaling pathway and excessive inflammatory responses. ( Chen, LJ; Ding, YB; Du, J; Jiang, SH; Li, AZ; Li, KZ; Li, MC; Ma, PL; Shi, CX; Zhou, HD, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, B | 1 |
| Yang, H | 1 |
| Zhang, J | 1 |
| Wang, X | 1 |
| Sun, H | 1 |
| Hu, F | 1 |
| Li, Q | 1 |
| Jiang, L | 1 |
| Su, Y | 1 |
| Peng, Q | 1 |
| Tang, Y | 1 |
| Liu, WT | 1 |
| He, X | 1 |
| Fan, Y | 1 |
| Zhu, X | 1 |
| Pereira, SM | 1 |
| Sinedino, BE | 1 |
| Costa, ELV | 1 |
| Morais, CCA | 1 |
| Sklar, MC | 1 |
| Adkson Sales Lima, C | 1 |
| Nakamura, MAM | 1 |
| Ranzani, OT | 1 |
| Goligher, EC | 1 |
| Tucci, MR | 1 |
| Ho, YL | 1 |
| Taniguchi, LU | 1 |
| Vieira, JE | 1 |
| Brochard, L | 1 |
| Amato, MBP | 1 |
| Chen, LJ | 1 |
| Ding, YB | 1 |
| Ma, PL | 1 |
| Jiang, SH | 1 |
| Li, KZ | 1 |
| Li, AZ | 1 |
| Li, MC | 1 |
| Shi, CX | 1 |
| Du, J | 1 |
| Zhou, HD | 1 |
| Nielsen, TK | 1 |
| Hvas, CL | 1 |
| Dobson, GP | 1 |
| Tønnesen, E | 1 |
| Granfeldt, A | 1 |
| Zhang, Z | 1 |
| Zhou, J | 1 |
| Liao, C | 1 |
| Li, X | 1 |
| Liu, M | 1 |
| Song, D | 1 |
| Jiang, X | 1 |
| Schley, MT | 1 |
| Casutt, M | 1 |
| Haberthür, C | 1 |
| Dusch, M | 1 |
| Rukwied, R | 1 |
| Schmelz, M | 1 |
| Schmeck, J | 1 |
| Schüpfer, GK | 1 |
| Konrad, CJ | 1 |
6 other studies available for lidocaine and Lung Injury, Acute
| Article | Year |
|---|---|
Lidocaine Alleviates Sepsis-Induced Acute Lung Injury in Mice by Suppressing Tissue Factor and Matrix Metalloproteinase-2/9.
Topics: Acute Lung Injury; Animals; Gene Expression Regulation; Lidocaine; Lipopolysaccharides; Male; Matrix | 2021 |
Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury.
Topics: Acute Lung Injury; Animals; Critical Illness; Disease Models, Animal; Female; Humans; Lidocaine; Phr | 2022 |
The protective effect of lidocaine on lipopolysaccharide-induced acute lung injury in rats through NF-κB and p38 MAPK signaling pathway and excessive inflammatory responses.
Topics: Acute Lung Injury; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Inflammation Media | 2018 |
Pulmonary function after hemorrhagic shock and resuscitation in a porcine model.
Topics: Acute Lung Injury; Adenosine; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Cytokines; Drug Comb | 2014 |
RAGE deficiency attenuates the protective effect of Lidocaine against sepsis-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Gene Knockout Techniques; HMGB1 Protein; Inflammation; Lidocaine; MAP Ki | 2017 |
Long-acting local anesthetics attenuate FMLP-induced acute lung injury in rats.
Topics: Acute Lung Injury; Amides; Anesthesia, Local; Animals; Anti-Inflammatory Agents; Bupivacaine; Endoth | 2009 |