Page last updated: 2024-10-28

lidocaine and Liver Dysfunction

lidocaine has been researched along with Liver Dysfunction in 52 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The lidocaine (MEGX [monoethylglycinexylidide]) test, which was performed in 200 patients with different liver diseases and in 23 organ donors, was compared with common laboratory tests."3.70The lidocaine (MEGX) test as an index of hepatic function: its clinical usefulness in liver surgery. ( Callivà, R; Cavallari, A; Cescon, M; Ercolani, G; Grazi, GL; Mazziotti, A; Pierangeli, F, 2000)
"Patients with acute hepatitis and patients with compensated or decompensated cirrhosis of the liver have a decreased plasma clearance of hexobarbital."3.66[Drug metabolism in patients with liver disease (author's transl)]. ( Epping, J; Fuchshofen-Röckel, M; Heusler, H; Richter, E; Zilly, W, 1980)
"The plasma half lives of antipyrine, paracetamol, and lignocaine given by mouth were measured in 23 patients with stable chronic liver diseases of varying severity."3.65Antipyrine, paracetamol, and lignocaine elimination in chronic liver disease. ( Adjepon-Yamoah, KK; Finlayson, ND; Forrest, JA; Prescott, LF, 1977)
" Plasma concentrations of free (unbound) and total valdecoxib and its active hydroxylated metabolite (SC-66905) were measured following single and multiple dosing (day 1 and day 8)."2.71The effect of mild and moderate hepatic impairment on the pharmacokinetics of valdecoxib, a selective COX-2 inhibitor. ( Britto, MR; Mainka, MB; Parivar, K; Sarapa, N, 2005)
"Lidocaine concentration was significantly lower in PGE1 group than in control group at the end of the infusion."2.68[The effect of low-dose prostaglandin E1 on intra- and post-operative liver function]. ( Amaha, K; Hanaoka, K; Hayashida, M; Namiki, A; Shimada, Y, 1997)
", differences in the type and degree of liver dysfunction of the animals and patients examined, and in the type and dosage of the inducing agent used."2.44Enzyme inhibition and induction in liver disease. ( De Martin, S; Orlando, R; Palatini, P; Pegoraro, P, 2008)
"Lidocaine has been shown to attenuate ischemia-reperfusion (I/R) injury in the heart, lung, and brain, potentially due to modulation of inflammatory responses and apoptotic signaling pathways."1.38Systemic lidocaine does not attenuate hepatic dysfunction after liver surgery in rats. ( de Graaf, W; Diepenhorst, GM; Erdogan, D; Herroeder, S; Hollmann, MW; van Gulik, TM, 2012)
"Lidocaine half-life was significantly lower in HIV-patients without ART."1.35Evaluation of quantitative liver function tests in HIV-positive patients under anti-retroviral therapy. ( Beste, M; Gerken, G; Kahraman, A; Miller, M; Ross, B, 2009)
"Patients with liver cirrhosis of different aetiology showed significantly higher Lidocain plasma concentrations and lower MEGX values than patients with chronic non-cirrhotic liver disease."1.29[Lidocaine elimination and MEGX formation after oral lidocaine administration--a practicable test for assessment of quantitative liver function]. ( Bomhard, M; Dorer, J; Joeres, R; Keller, F; Klinker, H; Richter, E; Zilly, W, 1993)
"Lidocaine (1 mg/kg) was injected i."1.29Assessment of lidocaine metabolite formation in comparison with other quantitative liver function tests. ( Luo, H; Meyer-Wyss, B; Renner, E; Scholer, A, 1993)
"PABA is well absorbed by the gastrointestinal tract and acetylated and conjugated in the liver to glycine before being excreted."1.29Preliminary assessment of glycine conjugation of para-aminobenzoic acid as a quantitative test of liver function. ( Barr, SB; Duffy, LF; Kerzner, B; Seeff, L; Soldin, SJ, 1995)
"Allopurinol and caffeine have been used to measure metabolite formation followed by renal elimination of both parent substance and metabolite."1.28Liver function assessment by drug metabolism. ( Barstow, L; Small, RE, 1990)
"Lidocaine toxicity was life-threatening or significantly complicated the management of 15 patients."1.26Excessive serum lidocaine levels during maintenance infusions: mechanisms and prevention. ( Atkinson, AJ; Davison, R; Parker, M, 1982)
"The pharmacokinetic parameters of lidocaine are pertinent to the determination of both appropriate loading doses and constant infusion rates that achieve a therapeutic plasma concentration while avoiding toxicity."1.26Pharmacokinetic principles of lidocaine dosing in relation to disease state. ( Waller, ES, 1981)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199024 (46.15)18.7374
1990's18 (34.62)18.2507
2000's9 (17.31)29.6817
2010's1 (1.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Palatini, P1
De Martin, S1
Pegoraro, P1
Orlando, R1
Miller, M1
Kahraman, A1
Ross, B1
Beste, M2
Gerken, G2
de Graaf, W1
Diepenhorst, GM1
Herroeder, S1
Erdogan, D1
Hollmann, MW1
van Gulik, TM1
Chen, MY1
Li, CH1
Huang, ZQ1
Liu, JC1
Zhou, NX1
Huang, XQ1
Wang, YS1
Piwowarska, J1
Kuczyñska, J1
Pachecka, J1
Sarapa, N1
Britto, MR1
Mainka, MB1
Parivar, K1
Ascione, R1
Talpahewa, S1
Rajakaruna, C1
Reeves, BC1
Lovell, AT1
Cohen, A1
Angelini, GD1
Jochum, C1
Penndorf, V1
Farahani, MS1
Testa, G1
Nadalin, S1
Malago, M1
Broelsch, CE1
Endell, W1
Oltmanns, D1
Pottage, T1
Davison, R1
Parker, M1
Atkinson, AJ1
Waller, ES1
Chow, MS1
Ronfeld, RA1
Ruffett, D1
Fieldman, A1
Richter, E2
Epping, J1
Fuchshofen-Röckel, M1
Heusler, H1
Zilly, W2
Klinker, H1
Joeres, R1
Bomhard, M1
Keller, F1
Dorer, J1
Walsh, RM1
Tanaka, J1
Malchesky, PS1
Sato, N1
Nakayama, S1
Vogt, DP1
Broughan, TA1
Hermann, RE1
Castellani, WJ1
Van Thiel, DH1
Hassanein, T1
Meyer-Wyss, B1
Renner, E1
Luo, H1
Scholer, A1
Potter, JM1
Wright, M1
Lynch, SV1
Strong, RW1
Henderson, A1
Balderson, G1
Walker, NI1
Hickman, PE1
Shimanuki, K1
Suzuki, W1
Sakurabayashi, I1
Kiyozaki, H1
Shinohara, K1
Soda, K1
Kai, T1
Satake, M1
Miyata, M1
Luketic, VA1
Shiffman, ML1
Fisher, RA1
Sanyal, AJ1
Purdum, PP1
Posner, MP1
Duffy, LF1
Kerzner, B1
Seeff, L1
Barr, SB1
Soldin, SJ1
Zoedler, T1
Ebener, C1
Becker, H1
Roeher, HD1
Hayashida, M1
Hanaoka, K1
Shimada, Y1
Namiki, A1
Amaha, K1
Tanaka, E1
Yasuhara, H1
Kupcová, V2
Turecký, L1
Szántová, M1
Schmidtová, K1
Ercolani, G1
Grazi, GL1
Callivà, R1
Pierangeli, F1
Cescon, M1
Cavallari, A1
Mazziotti, A1
Ol'rikh, M1
Kukes, VG1
Igonin, AA1
Perovic, J1
Petrovic, V1
Obradovic, O1
Todorovic, L1
Colgan, FJ1
Asahara, A1
Ueda, H1
Hishinuma, S1
Takagi, M1
Bond, WS1
Itoh, K1
Furudate, M1
Nasuhara, K1
Irie, G1
Aburano, T1
Kuwajima, A1
Koizumi, K1
Hutatsuya, R1
Tonami, N1
Hisada, K1
Ito, K1
Kawaguchi, S1
Iio, M1
Yamada, H1
Murata, H1
Chiba, K1
Matsui, K1
Toyama, H1
Prescott, LF3
Forrest, JA3
Adjepon-Yamoah, KK3
Finlayson, ND3
Meyer, B1
Luo, HS1
Bargetzi, M1
Renner, EL1
Stalder, GA1
Oellerich, M1
Burdelski, M1
Ringe, B1
Wittekind, C1
Lamesch, P1
Lautz, HU1
Gubernatis, G1
Beyrau, R1
Pichlmayr, R1
Weiss, M1
Barstow, L1
Small, RE1
Gremse, DA1
A-Kader, HH1
Schroeder, TJ1
Balistreri, WF1
Gueugniaud, PY1
Guerin, C1
Mahul, P1
Deu, C1
Robert, D1
Miyamoto, M1
Hayano, Y1
Noguchi, T1
Oda, S1
Taniguchi, K1
Honda, N1
Ebihara, A1
Dunn, GD1
Hayes, P1
Breen, KJ1
Schenker, S1
Black, M1
Kessler, KM1
Josephson, ME1
Caracta, AR1
Lau, SH1
Gallagher, JJ1
Damato, AN1
Levy, RH1
Smith, GH1
Thomson, PD1
Rowland, M1
Melmon, KL1
Hernandez, C1
Cachin, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005306]0 participants Observational1988-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for lidocaine and Liver Dysfunction

ArticleYear
Enzyme inhibition and induction in liver disease.
    Current clinical pharmacology, 2008, Volume: 3, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzy

2008
Assessment of liver function: the current situation.
    The Journal of the Oklahoma State Medical Association, 1995, Volume: 88, Issue:1

    Topics: Caffeine; Cytochrome P-450 Enzyme System; Humans; Lidocaine; Liver; Liver Circulation; Liver Disease

1995
[Evaluation of liver function in liver diseases using drugs as indicators].
    The Journal of toxicological sciences, 1997, Volume: 22, Issue:3

    Topics: Aminopyrine; Antipyrine; Erythromycin; Humans; Lidocaine; Liver; Liver Diseases; Liver Function Test

1997
[Importance of determination of monoethylglycinexylidide (MEGX)--as a liver function test in hepatology and liver transplantation].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:1

    Topics: Animals; Humans; Lidocaine; Liver Diseases; Liver Function Tests; Liver Transplantation

1999
Problems with postoperative drug therapy.
    Advances in surgery, 1977, Volume: 11

    Topics: Anesthesia; Anesthetics; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Drug Therap

1977
Drug metabolism in liver disease.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9

    Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; H

1975
The liver in congestive heart failure: a review.
    The American journal of the medical sciences, 1973, Volume: 265, Issue:3

    Topics: Alkaline Phosphatase; Anticoagulants; Ascites; Bilirubin; Digitalis Glycosides; Diuretics; Heart Fai

1973
Liver disease and drug therapy.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Amobarbital; Azathioprine; Half-Life; Humans; Lidocaine; Liver Cirrhosis; Liver Diseases; Metabolic

1974
Individualization of dosage of antiarrhythmic drugs.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Heart Diseases; Humans; Ki

1974

Trials

3 trials available for lidocaine and Liver Dysfunction

ArticleYear
The effect of mild and moderate hepatic impairment on the pharmacokinetics of valdecoxib, a selective COX-2 inhibitor.
    European journal of clinical pharmacology, 2005, Volume: 61, Issue:4

    Topics: Adult; Aged; Area Under Curve; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450

2005
Splanchnic organ injury during coronary surgery with or without cardiopulmonary bypass: a randomized, controlled trial.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:1

    Topics: Aged; Alanine Transaminase; Amylases; Aspartate Aminotransferases; Blood Glucose; Carbohydrates; Car

2006
[The effect of low-dose prostaglandin E1 on intra- and post-operative liver function].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:5

    Topics: Abdomen; Adult; Alprostadil; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Local; Dose-

1997

Other Studies

40 other studies available for lidocaine and Liver Dysfunction

ArticleYear
Evaluation of quantitative liver function tests in HIV-positive patients under anti-retroviral therapy.
    European journal of medical research, 2009, Sep-01, Volume: 14, Issue:9

    Topics: Adult; Antiviral Agents; Female; Galactose; Half-Life; Hepatitis B; Hepatitis C; HIV Infections; Hum

2009
Systemic lidocaine does not attenuate hepatic dysfunction after liver surgery in rats.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:3

    Topics: Animals; Lidocaine; Liver Diseases; Male; Postoperative Complications; Random Allocation; Rats; Rats

2012
Protective effects of lidocaine injected into the hepatoduodenal ligament on warm ischemia-reperfusion injury to the rat liver.
    Chinese medical journal, 2004, Volume: 117, Issue:2

    Topics: Animals; Duodenum; Injections; Lidocaine; Ligaments; Liver; Liver Diseases; Male; Rats; Rats, Spragu

2004
Liquid chromatographic method for the determination of lidocaine and monoethylglycine xylidide in human serum containing various concentrations of bilirubin for the assessment of liver function.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Jun-05, Volume: 805, Issue:1

    Topics: Bilirubin; Calibration; Chromatography, High Pressure Liquid; Humans; Lidocaine; Liver Diseases; Liv

2004
Quantitative liver function tests in donors and recipients of living donor liver transplantation.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2006, Volume: 12, Issue:4

    Topics: Adult; Female; Galactose; Half-Life; Humans; Indocyanine Green; Lidocaine; Liver Diseases; Liver Fun

2006
Alteration of the kinetics of tocainide in combined hepatic and renal insufficiency.
    Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:8

    Topics: Anti-Arrhythmia Agents; Humans; Kidney Diseases; Lidocaine; Liver Diseases; Metabolic Clearance Rate

1983
Excessive serum lidocaine levels during maintenance infusions: mechanisms and prevention.
    American heart journal, 1982, Volume: 104, Issue:2 Pt 1

    Topics: Aged; Arrhythmias, Cardiac; Body Weight; Chromatography, Gas; Disease Susceptibility; Heart Arrest;

1982
Pharmacokinetic principles of lidocaine dosing in relation to disease state.
    Journal of clinical pharmacology, 1981, Volume: 21, Issue:4

    Topics: Adult; Age Factors; Aged; Animals; Dogs; Drug Therapy, Combination; Half-Life; Heart Failure; Humans

1981
Lidocaine pharmacokinetics during cardiac arrest and external cardiopulmonary resuscitation.
    American heart journal, 1981, Volume: 102, Issue:4

    Topics: Adult; Aged; Cardiac Output; Coronary Circulation; Female; Femoral Artery; Femoral Vein; Heart Arres

1981
[Drug metabolism in patients with liver disease (author's transl)].
    Leber, Magen, Darm, 1980, Volume: 10, Issue:5

    Topics: Acute Disease; Adult; Antipyrine; Biological Availability; Biotransformation; Cholestasis; Female; H

1980
[Lidocaine elimination and MEGX formation after oral lidocaine administration--a practicable test for assessment of quantitative liver function].
    Zeitschrift fur Gastroenterologie, 1993, Volume: 31 Suppl 2

    Topics: Administration, Oral; Humans; Lidocaine; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Meta

1993
Monoethylglycinexylidide formation as an independent measure of warm hepatic ischemia and reperfusion injury.
    The Journal of surgical research, 1995, Volume: 59, Issue:3

    Topics: Adenosine Triphosphate; Animals; Hot Temperature; Lidocaine; Liver; Liver Diseases; Male; Mitochondr

1995
Assessment of lidocaine metabolite formation in comparison with other quantitative liver function tests.
    Journal of hepatology, 1993, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aminopyrine; Breath Tests; Child; Galactose; Humans; Lidocaine; Liver Diseases; L

1993
Lignocaine metabolism and liver function testing in primary graft failure following orthotopic liver transplantation.
    The Medical journal of Australia, 1993, Jan-18, Volume: 158, Issue:2

    Topics: Female; Graft Rejection; Humans; Lidocaine; Liver Diseases; Liver Function Tests; Liver Transplantat

1993
[Evaluation of lidocaine metabolite (monoethylglycinexylidide) as a liver function test].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1993, Volume: 90, Issue:1

    Topics: Evaluation Studies as Topic; Female; Fluorescence Polarization Immunoassay; Humans; Lidocaine; Liver

1993
Hepatic lidocaine metabolism is useful in the selection of patients in need of liver transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Hepatitis; Humans; Lidocaine; Liver; Liver Cirrhosis; Liver Diseases; Liver Transplantation

1993
Preliminary assessment of glycine conjugation of para-aminobenzoic acid as a quantitative test of liver function.
    Clinical biochemistry, 1995, Volume: 28, Issue:5

    Topics: 4-Aminobenzoic Acid; Adolescent; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Bil

1995
Evaluation of liver function tests to predict operative risk in liver surgery.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1995, Volume: 9, Issue:1

    Topics: Galactose; Humans; Indocyanine Green; Lidocaine; Liver Diseases; Liver Failure; Liver Function Tests

1995
[Monoethylglycinexylidide--a metabolite of lidocaine--as an index of liver function in chronic hepatic parenchymal diseases].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:1

    Topics: Adult; Aged; Chronic Disease; Female; Fluorescence Polarization Immunoassay; Humans; Lidocaine; Live

1999
The lidocaine (MEGX) test as an index of hepatic function: its clinical usefulness in liver surgery.
    Surgery, 2000, Volume: 127, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Carcinoma, Hepatocellular

2000
[Role of lidocaine metabolism studies in the diagnosis of liver diseases].
    Klinicheskaia laboratornaia diagnostika, 2000, Issue:7

    Topics: Adult; Animals; Clinical Enzyme Tests; Critical Care; Diagnosis, Differential; Dogs; Female; Hepatit

2000
The influence of liver functional ability on blood levels of lidocaine after intraoral submucous application.
    Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie, 1979, Volume: 22, Issue:2

    Topics: Female; Humans; Injections; Lidocaine; Liver; Liver Diseases; Male

1979
[Studies of hepatobiliary scintigraphy and functional examination with 99mTc-HIDA (author's transl)].
    Radioisotopes, 1979, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Biliary Tract; Biliary Tract Diseases; Child; Child, Preschool; Evaluation Studie

1979
Clinical relevance of the effect of hepatic disease on drug disposition.
    American journal of hospital pharmacy, 1978, Volume: 35, Issue:4

    Topics: Anti-Infective Agents; Antineoplastic Agents; Central Nervous System; Digoxin; Humans; Lidocaine; Li

1978
[Hepatobiliary scintigraphy with a new 99mTc-tagged radiopharmaceutical, 99mTc-HIDA. (author's transl)].
    Kaku igaku. The Japanese journal of nuclear medicine, 1978, Volume: 15, Issue:5

    Topics: Aged; Biliary Tract Diseases; Drug Evaluation; Female; Humans; Iodine Radioisotopes; Lidocaine; Live

1978
[Clinical usefulness of 99mTc-HIDA hepatobiliary scintigraphy (author's transl)].
    Kaku igaku. The Japanese journal of nuclear medicine, 1978, Volume: 15, Issue:5

    Topics: Biliary Tract Diseases; Drug Evaluation; Humans; Lidocaine; Liver Diseases; Radionuclide Imaging; Te

1978
[Evaluation of 99mTc-HIDA (n-2.6 dimethylphenylcarbamoylmethyl iminodiacetic acid) scanning in the various hepatobiliary disorders (author's transl)].
    Kaku igaku. The Japanese journal of nuclear medicine, 1978, Volume: 15, Issue:7

    Topics: Adult; Aged; Biliary Tract Diseases; Drug Evaluation; Female; Humans; Lidocaine; Liver Diseases; Mal

1978
Antipyrine, paracetamol, and lignocaine elimination in chronic liver disease.
    British medical journal, 1977, May-28, Volume: 1, Issue:6073

    Topics: Acetaminophen; Adult; Aged; Antipyrine; Chronic Disease; Female; Half-Life; Humans; Kinetics; Lidoca

1977
Proceedings: Antipyrine, lingocaine and paracetamol metabolism in chronic liver disease.
    Gut, 1975, Volume: 16, Issue:10

    Topics: Acetaminophen; Adult; Aged; Antipyrine; Chronic Disease; Female; Humans; Lidocaine; Liver Diseases;

1975
Quantitation of intrinsic drug-metabolizing capacity in human liver biopsy specimens: support for the intact-hepatocyte theory.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:3

    Topics: Adrenergic beta-Antagonists; Ethanolamines; Hepatitis, Chronic; Humans; Lidocaine; Liver; Liver Cirr

1991
Functional state of the donor liver and early outcome of transplantation.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 2

    Topics: Graft Survival; Humans; Lidocaine; Liver Diseases; Liver Function Tests; Liver Transplantation; Prog

1991
Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction.
    Clinical pharmacokinetics, 1990, Volume: 18, Issue:5

    Topics: Absorption; Antipyrine; Biological Availability; Caffeine; Diphenhydramine; Dose-Response Relationsh

1990
Liver function assessment by drug metabolism.
    Pharmacotherapy, 1990, Volume: 10, Issue:4

    Topics: Acetamides; Adult; Allopurinol; Aminopyrine; Caffeine; Half-Life; Humans; Indocyanine Green; Lidocai

1990
Assessment of lidocaine metabolite formation as a quantitative liver function test in children.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:3 Pt 1

    Topics: Adolescent; Bilirubin; Child; Child, Preschool; Chronic Disease; Fluoroimmunoassay; Humans; Infant;

1990
[Torsade de pointes induced by the combination lidocaine-erythromycin and hepatic insufficiency].
    Presse medicale (Paris, France : 1983), 1985, Apr-20, Volume: 14, Issue:16

    Topics: Aged; Drug Therapy, Combination; Erythromycin; Humans; Lidocaine; Liver Diseases; Male; Tachycardia

1985
[Plasma lidocaine concentrations during epidural anesthesia--a comparison between patients with normal liver functions and those with abnormal functions].
    Masui. The Japanese journal of anesthesiology, 1988, Volume: 37, Issue:6

    Topics: Adult; Aged; Anesthesia, Epidural; Female; Humans; Lidocaine; Liver; Liver Diseases; Male; Middle Ag

1988
Effects of lidocaine on refractory periods in man.
    American heart journal, 1972, Volume: 84, Issue:6

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Catheterization; Electrocardiography; Female; Heart Atria

1972
Dosage regimens of antiarrhythmics. II. Applications.
    American journal of hospital pharmacy, 1973, Volume: 30, Issue:6

    Topics: Anti-Arrhythmia Agents; Heart Failure; Humans; Injections, Intravenous; Kidney Diseases; Lidocaine;

1973
The influence of heart failure, liver disease, and renal failure on the disposition of lidocaine in man.
    American heart journal, 1971, Volume: 82, Issue:3

    Topics: Arrhythmias, Cardiac; Heart Failure; Humans; Kidney; Kidney Failure, Chronic; Lidocaine; Liver; Live

1971
[Morphologic methods of studying the hepatic circulation: selective arteriography, portography and cavography].
    Revue internationale d'hepatologie, 1967, Volume: 17, Issue:8

    Topics: Angiography; Hemodynamics; Humans; Iodine Isotopes; Lidocaine; Liver Circulation; Liver Diseases; Me

1967