lidocaine has been researched along with Leukemia L 1210 in 4 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine did not increase directly BLM A2-induced breakage of DNA in vitro as measured by loss of form I pAT 153 DNA, but it did increase BLM A2-induced DNA strand breaks in intact L1210 cells coincubated with lidocaine and BLM A2." | 1.27 | Lidocaine potentiation of bleomycin A2 cytotoxicity and DNA strand breakage in L1210 and human A-253 cells. ( Braun, ID; Kennedy, KA; Lazo, JS; Meandzija, B; Pham, ET; Smaldone, LF, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Selassie, CD | 1 |
| Hansch, C | 1 |
| Khwaja, TA | 1 |
| Kennedy, KA | 2 |
| Hait, WN | 1 |
| Lazo, JS | 2 |
| Keyes, SR | 1 |
| Hickman, JA | 1 |
| Sartorelli, AC | 1 |
| Braun, ID | 1 |
| Meandzija, B | 1 |
| Pham, ET | 1 |
| Smaldone, LF | 1 |
4 other studies available for lidocaine and Leukemia L 1210
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; | 1990 |
Chemical modulation of bleomycin induced toxicity.
Topics: Animals; Antineoplastic Agents; Bleomycin; Calmodulin; DNA Damage; Drug Synergism; In Vitro Techniqu | 1986 |
The effects of adriamycin on intracellular calcium concentrations of L1210 murine leukemia cells.
Topics: Animals; Calcium; Doxorubicin; In Vitro Techniques; Intracellular Fluid; Leukemia L1210; Lidocaine; | 1987 |
Lidocaine potentiation of bleomycin A2 cytotoxicity and DNA strand breakage in L1210 and human A-253 cells.
Topics: Animals; Bleomycin; Calmodulin; Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; DNA Repair | 1985 |