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lidocaine and Lesion of Sciatic Nerve

lidocaine has been researched along with Lesion of Sciatic Nerve in 13 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone was found to produce a statistically significant decrease in heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain after intraperitoneal injection."7.72Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004)
"Systemic lidocaine and other local anesthetics reduce hypersensitivity states induced by both acute inflammation and peripheral nerve injury in animals and produce analgesia in some patients with chronic pain."3.72Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac. ( Du, W; Eisenach, JC; Ma, W, 2003)
"Amiodarone was found to produce a statistically significant decrease in heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain after intraperitoneal injection."3.72Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004)
"A 17-yr-old boy developed bilateral sciatic neuropathy after a nine-hour cardiac surgical procedure in the supine position, resulting in debilitating dysesthesia refractory to neuropathic pain therapies and leading to severe functional limitation."1.39Ultrasound-guided perineural steroid injection to treat intractable pain due to sciatic nerve injury. ( Chan, RC; Chiou, HJ; Hsu, YC; Lu, JH; Wang, JC; Yang, TF, 2013)
" Both morphine and lidocaine retained topical activity following chronic sciatic nerve injury, but their analgesic dose-response curves were shifted to the right when compared to sham-operated mice."1.34Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: correlation with morphine and lidocaine analgesia. ( El-Maarouf Abderrahman, A; El-Maarouf, A; Kolesnikov, Y; Pasternak, G; Rutinhauser, U; Rutishauser, U, 2007)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (61.54)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, JM1
Choi, SH1
Wang, JC1
Chiou, HJ1
Lu, JH1
Hsu, YC1
Chan, RC1
Yang, TF1
Eftaxiopoulou, T1
Macdonald, W1
Britzman, D1
Bull, AM1
Rossaneis, AC1
Genaro, K1
Dias, QM1
Guethe, LM1
Fais, RS1
Del Bel, EA1
Prado, WA1
Pitcher, GM1
Henry, JL1
Rose, K1
Ooi, L1
Dalle, C1
Robertson, B1
Wood, IC1
Gamper, N1
Ma, W1
Du, W1
Eisenach, JC1
Datta, S1
Waghray, T1
Torres, M1
Glusman, S1
Mert, T1
Daglioglu, YK1
Gunay, I1
Gocmen, C1
Sotgiu, ML1
Valente, M1
Caramenti, GC1
Biella, GE1
Kolesnikov, Y1
El-Maarouf, A1
El-Maarouf Abderrahman, A1
Rutishauser, U1
Rutinhauser, U1
Pasternak, G1
Lim, TK1
Macleod, BA1
Ries, CR1
Schwarz, SK1
Bileviciute-Ljungar, I1
Lundeberg, T1

Other Studies

13 other studies available for lidocaine and Lesion of Sciatic Nerve

ArticleYear
Reversing Effect of Insulin on Local Anesthetics-Induced Sciatic Nerve Block in Rats.
    BioMed research international, 2019, Volume: 2019

    Topics: Anesthesia, Local; Animals; Bupivacaine; Disease Models, Animal; Drug Combinations; Humans; Insulin;

2019
Ultrasound-guided perineural steroid injection to treat intractable pain due to sciatic nerve injury.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:9

    Topics: Adolescent; Anesthetics, Local; Cardiac Surgical Procedures; Glucocorticoids; Humans; Lidocaine; Mag

2013
Gait compensations in rats after a temporary nerve palsy quantified using temporo-spatial and kinematic parameters.
    Journal of neuroscience methods, 2014, Jul-30, Volume: 232

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Biomechanical Phenomena; Chi-Square Distribution;

2014
Descending mechanisms activated by the anterior pretectal nucleus initiate but do not maintain neuropathic pain in rats.
    European journal of pain (London, England), 2015, Volume: 19, Issue:8

    Topics: Anesthetics, Local; Animals; Constriction, Pathologic; Hyperalgesia; Lidocaine; Male; Methysergide;

2015
Governing role of primary afferent drive in increased excitation of spinal nociceptive neurons in a model of sciatic neuropathy.
    Experimental neurology, 2008, Volume: 214, Issue:2

    Topics: Anesthetics, Local; Animals; Disease Models, Animal; Lidocaine; Male; Membrane Potentials; Nerve Blo

2008
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury.
    Pain, 2011, Volume: 152, Issue:4

    Topics: Aminopyridines; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Dise

2011
Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac.
    Anesthesiology, 2003, Volume: 98, Issue:1

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Dose-Response Relationship

2003
Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Amiodarone; Anesthetics, Local; Animals; Cold Temperature; Hot Temperature; Hyperalgesia; Injections

2004
Changes in electrophysiological properties of regenerating rat peripheral nerves after crush injury.
    Neuroscience letters, 2004, Jun-17, Volume: 363, Issue:3

    Topics: 4-Aminopyridine; Action Potentials; Animals; Electric Stimulation; Electrophysiology; Female; Lidoca

2004
Heterotopic inputs facilitate poststimulus afterdischarges of spinal WDR neurons in rats with chronic nerve constriction.
    Brain research, 2006, Jul-12, Volume: 1099, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Constriction; Dis

2006
Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: correlation with morphine and lidocaine analgesia.
    European journal of pharmacology, 2007, Jul-30, Volume: 568, Issue:1-3

    Topics: Analgesia; Analgesics, Opioid; Anesthetics, Local; Animals; Constriction; Drug Therapy, Combination;

2007
The quaternary lidocaine derivative, QX-314, produces long-lasting local anesthesia in animal models in vivo.
    Anesthesiology, 2007, Volume: 107, Issue:2

    Topics: Action Potentials; Anesthesia, Local; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Resp

2007
Contralateral treatment with xylocaine reduces nociceptive behaviour in mononeuropathic rats.
    Neuroreport, 2000, Feb-07, Volume: 11, Issue:2

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Functional Laterality; Hindlimb; Hot Temperature; Inj

2000