lidocaine has been researched along with Leigh Disease in 2 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Leigh Disease: A group of metabolic disorders primarily of infancy characterized by the subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, dysphagia, and lactic acidosis. Pathological features include spongy degeneration of the neuropile of the basal ganglia, thalamus, brain stem, and spinal cord. Patterns of inheritance include X-linked recessive, autosomal recessive, and mitochondrial. Leigh disease has been associated with mutations in genes for the PYRUVATE DEHYDROGENASE COMPLEX; CYTOCHROME-C OXIDASE; ATP synthase subunit 6; and subunits of mitochondrial complex I. (From Menkes, Textbook of Child Neurology, 5th ed, p850).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shear, T | 1 |
| Tobias, JD | 1 |
| Ellis, Z | 1 |
| Bloomer, C | 1 |
2 other studies available for lidocaine and Leigh Disease
| Article | Year |
|---|---|
Anesthetic implications of Leigh's syndrome.
Topics: Anesthesia, Spinal; Anesthetics, Local; Biopsy; Bronchodilator Agents; Epinephrine; Female; Humans; | 2004 |
Outpatient anesthesia for oral surgery in a juvenile with Leigh disease.
Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Intravenous; Anesthetic | 2005 |