Page last updated: 2024-10-28

lidocaine and Laryngeal Spasm

lidocaine has been researched along with Laryngeal Spasm in 38 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The preventive effect of lidocaine against coughing in the recovery period after general anaesthesia was observed."9.05Lidocaine given intravenously as a suppressant of cough and laryngospasm in connection with extubation after tonsillectomy. ( Andersen, LW; Friesel, E; Gefke, K, 1983)
"Lidocaine gel was an effective drug that can be used to attenuate the incidence rate of post-operative sore throat."7.30Comparing the effectiveness of topical dexamethasone emollient, lidocaine gel, and glycerin emollient on the endotracheal tube for postoperative hoarseness of voice, sore throat, and laryngospasm. ( Jabbar, ML; Mahboba, JH; Meazher, N, 2023)
"The purpose of this study was to evaluate the effects (common haemodynamic variables, peak cuff pressures, the incidence of reaction ('bucking') during extubation and the incidence of sore throat after operation) of lidocaine 10% instilled into the endotracheal tube cuff in intubated patients."5.09Lidocaine 10% in the endotracheal tube cuff: blood concentrations, haemodynamic and clinical effects. ( Akkan, G; Altintaş, F; Bozkurt, P; Kaya, G, 2000)
"The preventive effect of lidocaine against coughing in the recovery period after general anaesthesia was observed."5.05Lidocaine given intravenously as a suppressant of cough and laryngospasm in connection with extubation after tonsillectomy. ( Andersen, LW; Friesel, E; Gefke, K, 1983)
"Topical lidocaine application with mesh nebulizers decreases the most common complication, cough, after flexible bronchoscopy in children more effectively compare to jet nebulizers."4.02Two different methods of lidocaine inhalation before diagnostic flexible bronchoscopy: effects on post-bronchoscopy respiratory symptoms ( Açıkel, A; Topçu, İ; Yaşar, A; Yılmaz, Ö; Yüksel, H, 2021)
"Lidocaine gel was an effective drug that can be used to attenuate the incidence rate of post-operative sore throat."3.30Comparing the effectiveness of topical dexamethasone emollient, lidocaine gel, and glycerin emollient on the endotracheal tube for postoperative hoarseness of voice, sore throat, and laryngospasm. ( Jabbar, ML; Mahboba, JH; Meazher, N, 2023)
"Also laryngospasm, cough, and agitation scores were obtained during arousal."2.94Original Research: Aerosolized Lidocaine: Effective for Safer Arousal After Suspension Laryngoscopy. ( Develioğlu, ÖN; Güvenç, A; Külekçi, M; Paltura, C; Yelken, K, 2020)
"The incidence of laryngospasm and hemodynamic trends did not differ between the groups."2.75Endotracheal tube cuff lidocaine is not superior to intravenous lidocaine in short pediatric surgeries. ( Abouzari, M; Alagha, AE; Behzadi, M; Hajimohamadi, F; Rashidi, A, 2010)
"Postoperative stridor, laryngospasm, cyanosis, bleeding, sedation degree, and respiratory depression were observed, and plasma lidocaine levels were measured."2.69The use of preoperative lidocaine to prevent stridor and laryngospasm after tonsillectomy and adenoidectomy. ( Aygenç, E; Cekiç, A; Koç, C; Kocaman, F; Ozdem, C, 1998)
"The incidence of gagging (P = 0."2.68Comparison of propofol versus thiopentone with midazolam or lidocaine to facilitate laryngeal mask insertion. ( Bapat, P; Jago, RH; Joshi, RN; Young, E, 1996)
"Higher incidence and worse outcomes of laryngospasm during general anesthesia in children than adults have been reported for many years, but few prevention measures are put forward."2.53The Efficacy of Lidocaine in Laryngospasm Prevention in Pediatric Surgery: a Network Meta-analysis. ( Lai, Z; Li, S; Liu, X; Qi, X; Tan, W; Wang, Z, 2016)
"Upper gastrointestinal endoscopies (UGEs) performed under ketamine sedation may increase the risk of respiratory adverse events (RAEs) due to pharyngeal stimulation."1.51Topical Pharyngeal Lidocaine Reduces Respiratory Adverse Events During Upper Gastrointestinal Endoscopies Under Ketamine Sedation in Children. ( Estalella-Mendoza, A; Flores-González, JC; Lechuga-Sancho, AM; Rodríguez-Campoy, P; Saldaña-Valderas, M, 2019)
"Intraoperative laryngospasm occurs in <1% of cases."1.51Nebulized Lidocaine in the Treatment of Refractory Postoperative Laryngospasm: A Case Report. ( Ha, CB; Oon, Z; Sicinski, M, 2019)
"The incidence of laryngospasm was reduced from 38% at baseline to 15% 2min after lidocaine administration (p<0."1.39The effect of intravenous lidocaine on laryngeal and respiratory reflex responses in anaesthetised children*. ( Erb, TO; Frei, FJ; Keller, K; von Ungern-Sternberg, BS, 2013)
"The relative frequency of PRAE (laryngospasm, coughing, desaturation <95%) associated with no use of topical airway lidocaine (TAL), with TAL sprayed directly onto the vocal cords, and TAL administered blindly into the pharynx was assessed."1.38Does topical lidocaine before tracheal intubation attenuate airway responses in children? An observational audit. ( Calder, A; Erb, TO; Hamilton, ND; Hegarty, M; von Ungern-Sternberg, BS, 2012)
"Three cases of post-extubation stridor due to suspected laryngospasm are described in which a small dose of lignocaine injected intra-tracheally, through the cricothyroid membrane, produced rapid and effective relief of stridor with no early recurrence or side-effects."1.34Transtracheal lignocaine: effective treatment for postextubation stridor. ( Lewis, KE, 2007)
"In this study, the canine model of laryngospasm previously described by Aviv, et al."1.28A canine model for studying laryngospasm and its prevention. ( Cohen, JI; Henderson, PS; Jarnberg, PO; Smith, JD; Stevens, W, 1992)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199010 (26.32)18.7374
1990's9 (23.68)18.2507
2000's6 (15.79)29.6817
2010's9 (23.68)24.3611
2020's4 (10.53)2.80

Authors

AuthorsStudies
Jabbar, ML1
Mahboba, JH1
Meazher, N1
Sun, R1
Bao, X1
Gao, X1
Li, T1
Wang, Q1
Li, Y1
Yüksel, H1
Yaşar, A1
Açıkel, A1
Topçu, İ1
Yılmaz, Ö1
Lubszczyk, M1
Łuczyńska-Sopel, A1
Polaczkiewicz, D1
Paltura, C1
Güvenç, A1
Develioğlu, ÖN1
Yelken, K1
Külekçi, M1
Flores-González, JC1
Estalella-Mendoza, A1
Rodríguez-Campoy, P1
Saldaña-Valderas, M1
Lechuga-Sancho, AM1
Oon, Z1
Ha, CB1
Sicinski, M1
Mihara, T1
Uchimoto, K1
Morita, S1
Goto, T1
Same, M1
Smith, J1
Qi, X1
Lai, Z1
Li, S1
Liu, X1
Wang, Z1
Tan, W1
Behzadi, M1
Hajimohamadi, F1
Alagha, AE1
Abouzari, M1
Rashidi, A1
Hamilton, ND1
Hegarty, M1
Calder, A1
Erb, TO2
von Ungern-Sternberg, BS2
Keller, K1
Frei, FJ1
Riley, RH1
Musk, MT1
Rex, MA4
Zeidan, A1
Halabi, D1
Baraka, A1
Lewis, KE1
Palencia-Herrejón, E1
Borrallo-Pérez, JM1
Pardo-Rey, C1
Gefke, K2
Andersen, LW2
Friesel, E2
Rhew, K1
Fiedler, DA1
Ludlow, CL1
Bapat, P1
Joshi, RN1
Young, E1
Jago, RH1
Cook, TM1
Seavell, CR1
Cox, CM1
Mevorach, DL1
Koç, C1
Kocaman, F1
Aygenç, E1
Ozdem, C1
Cekiç, A1
Altintaş, F1
Bozkurt, P1
Kaya, G1
Akkan, G1
Hooda, S1
Kiran, S1
Henderson, PS1
Cohen, JI1
Jarnberg, PO1
Smith, JD1
Stevens, W1
D'Eramo, EM1
Staffel, JG1
Weissler, MC1
Tyler, EP1
Drake, AF1
Raine, J1
Warner, JO1
Johnson, LA1
Robinson, EP1
Brown, TC1
Leicht, P1
Wisborg, T1
Chraemmer-Jørgensen, B1
Adamson, JE1
Cohen, BI1
Horton, CE1
Mladick, RA1
Gwyn, PP1
Biancato, LS1
Peng, AT1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Cold Vapor on Sore Throat and Dysphagia in the Early Postoperative Period After Suspension Laryngoscopy[NCT05287698]60 participants (Anticipated)Interventional2022-03-21Not yet recruiting
The Effect of Cold Vapor on Intubation-Related Symptoms and Comfort in the Early Postoperative Period[NCT05317156]120 participants (Anticipated)Interventional2022-04-18Not yet recruiting
Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429]Phase 4144 participants (Anticipated)Interventional2019-04-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for lidocaine and Laryngeal Spasm

ArticleYear
The efficacy of lidocaine to prevent laryngospasm in children: a systematic review and meta-analysis.
    Anaesthesia, 2014, Volume: 69, Issue:12

    Topics: Anesthesia, General; Anesthetics, Local; Child; Child, Preschool; Humans; Infant; Laryngismus; Lidoc

2014
The Efficacy of Lidocaine in Laryngospasm Prevention in Pediatric Surgery: a Network Meta-analysis.
    Scientific reports, 2016, 09-02, Volume: 6

    Topics: Anesthetics, Local; Child; Child, Preschool; Humans; Infant; Laryngismus; Lidocaine; Network Meta-An

2016
[Intubation of the critical patient].
    Medicina intensiva, 2008, Volume: 32 Spec No. 1

    Topics: Anesthetics, Local; Bronchoconstriction; Clinical Competence; Critical Illness; Humans; Intubation,

2008

Trials

13 trials available for lidocaine and Laryngeal Spasm

ArticleYear
Comparing the effectiveness of topical dexamethasone emollient, lidocaine gel, and glycerin emollient on the endotracheal tube for postoperative hoarseness of voice, sore throat, and laryngospasm.
    Journal of medicine and life, 2023, Volume: 16, Issue:6

    Topics: Emollients; Glycerol; Hoarseness; Humans; Laryngismus; Lidocaine; Pain; Pharyngitis

2023
The impact of topical lidocaine and timing of LMA removal on the incidence of airway events during the recovery period in children: a randomized controlled trial.
    BMC anesthesiology, 2021, 01-08, Volume: 21, Issue:1

    Topics: Administration, Topical; Anesthesia Recovery Period; Child, Preschool; China; Female; Humans; Incide

2021
Original Research: Aerosolized Lidocaine: Effective for Safer Arousal After Suspension Laryngoscopy.
    Journal of voice : official journal of the Voice Foundation, 2020, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aerosols; Aged; Anesthesia Recovery Period; Anesthetics, Local; Arterial Pressure

2020
Original Research: Aerosolized Lidocaine: Effective for Safer Arousal After Suspension Laryngoscopy.
    Journal of voice : official journal of the Voice Foundation, 2020, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aerosols; Aged; Anesthesia Recovery Period; Anesthetics, Local; Arterial Pressure

2020
Original Research: Aerosolized Lidocaine: Effective for Safer Arousal After Suspension Laryngoscopy.
    Journal of voice : official journal of the Voice Foundation, 2020, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aerosols; Aged; Anesthesia Recovery Period; Anesthetics, Local; Arterial Pressure

2020
Original Research: Aerosolized Lidocaine: Effective for Safer Arousal After Suspension Laryngoscopy.
    Journal of voice : official journal of the Voice Foundation, 2020, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aerosols; Aged; Anesthesia Recovery Period; Anesthetics, Local; Arterial Pressure

2020
Endotracheal tube cuff lidocaine is not superior to intravenous lidocaine in short pediatric surgeries.
    International journal of pediatric otorhinolaryngology, 2010, Volume: 74, Issue:5

    Topics: Anesthesia, General; Anesthetics, Local; Child; Child, Preschool; Cough; Double-Blind Method; Female

2010
The laryngeal reflex.
    New Zealand veterinary journal, 1967, Volume: 15, Issue:12

    Topics: Action Potentials; Administration, Inhalation; Anesthesia, Inhalation; Anesthetics, Inhalation; Anes

1967
Lidocaine given intravenously as a suppressant of cough and laryngospasm in connection with extubation after tonsillectomy.
    Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Cough; Double-Blind Method; Humans; Intubation, Intratracheal; Laryngismus; Lidoc

1983
Comparison of propofol versus thiopentone with midazolam or lidocaine to facilitate laryngeal mask insertion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Cough; Drug Costs; Elective Surgical Procedures

1996
Lignocaine to aid the insertion of the laryngeal mask airway with thiopentone. A comparison between topical and intravenous administration.
    Anaesthesia, 1996, Volume: 51, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Female; Humans; Laryngeal Masks

1996
The use of preoperative lidocaine to prevent stridor and laryngospasm after tonsillectomy and adenoidectomy.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1998, Volume: 118, Issue:6

    Topics: Adenoidectomy; Anesthetics, Local; Child; Female; Humans; Laryngismus; Lidocaine; Male; Postoperativ

1998
Lidocaine 10% in the endotracheal tube cuff: blood concentrations, haemodynamic and clinical effects.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Local; Blood Press

2000
Comparison of topical and intravenous lignocaine with thiopentone for insertion of laryngeal mask airway.
    Tropical doctor, 2001, Volume: 31, Issue:2

    Topics: Administration, Topical; Adult; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local;

2001
The prevention of postoperative stridor and laryngospasm with topical lidocaine.
    Archives of otolaryngology--head & neck surgery, 1991, Volume: 117, Issue:10

    Topics: Adenoidectomy; Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Child; Child, Pr

1991
Does intravenous lidocaine prevent laryngospasm after extubation in children?
    Anesthesia and analgesia, 1985, Volume: 64, Issue:12

    Topics: Child; Child, Preschool; Female; Humans; Injections, Intravenous; Intubation, Intratracheal; Laryngi

1985

Other Studies

22 other studies available for lidocaine and Laryngeal Spasm

ArticleYear
Two different methods of lidocaine inhalation before diagnostic flexible bronchoscopy: effects on post-bronchoscopy respiratory symptoms
    Turkish journal of medical sciences, 2021, 08-30, Volume: 51, Issue:4

    Topics: Adolescent; Bronchoscopy; Case-Control Studies; Child; Child, Preschool; Cough; Female; Humans; Lary

2021
Facial nerve palsy and laryngospasm as a complication of local anaesthesia during adenotonsillectomy.
    Auris, nasus, larynx, 2018, Volume: 45, Issue:5

    Topics: Adenoidectomy; Anesthesia, Local; Anesthetics, Local; Child, Preschool; Epinephrine; Facial Nerve Di

2018
Topical Pharyngeal Lidocaine Reduces Respiratory Adverse Events During Upper Gastrointestinal Endoscopies Under Ketamine Sedation in Children.
    Paediatric drugs, 2019, Volume: 21, Issue:1

    Topics: Anesthesia, Local; Anesthetics, Dissociative; Anesthetics, Local; Child; Child, Preschool; Conscious

2019
Nebulized Lidocaine in the Treatment of Refractory Postoperative Laryngospasm: A Case Report.
    A&A practice, 2019, Jul-01, Volume: 13, Issue:1

    Topics: Empyema, Pleural; Female; Humans; Laryngismus; Lidocaine; Middle Aged; Nebulizers and Vaporizers; Po

2019
Should neuromuscular blockers be used for every paediatric intubation?
    British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:6

    Topics: Analgesics, Opioid; Anaphylaxis; Anesthesiology; Anesthetics; Anesthetics, Inhalation; Anesthetics,

2016
Does topical lidocaine before tracheal intubation attenuate airway responses in children? An observational audit.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:4

    Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Cough; Female; Hum

2012
The effect of intravenous lidocaine on laryngeal and respiratory reflex responses in anaesthetised children*.
    Anaesthesia, 2013, Volume: 68, Issue:1

    Topics: Administration, Intravenous; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; A

2013
Laryngospasm induced by topical application of lignocaine.
    Anaesthesia and intensive care, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Humans; Laryngismus; Lidocaine; Middle Aged

2005
Aerosolized lidocaine for relief of extubation laryngospasm.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:5

    Topics: Adult; Aerosols; Anesthetics, Local; Female; Humans; Intubation, Intratracheal; Laryngismus; Lidocai

2005
Transtracheal lignocaine: effective treatment for postextubation stridor.
    Anaesthesia and intensive care, 2007, Volume: 35, Issue:1

    Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Intubation, Intratracheal; Laryngismus; Lidocaine;

2007
[Effect of intravenous lidocaine in laryngospasm].
    Ugeskrift for laeger, 1982, Jul-12, Volume: 144, Issue:28

    Topics: Adult; Anesthesia, General; Child; Female; Humans; Injections, Intravenous; Laryngismus; Lidocaine;

1982
Technique for injection of botulinum toxin through the flexible nasolaryngoscope.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1994, Volume: 111, Issue:6

    Topics: Adult; Anesthetics, Local; Botulinum Toxins; Catheterization; Female; Fiber Optic Technology; Humans

1994
The management and treatment of recurrent postoperative laryngospasm.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:5

    Topics: Adult; Anesthetics, Local; Humans; Laryngeal Nerves; Laryngismus; Lidocaine; Male; Nerve Block; Neur

1996
A canine model for studying laryngospasm and its prevention.
    The Laryngoscope, 1992, Volume: 102, Issue:11

    Topics: Administration, Topical; Anesthesia, Inhalation; Animals; Clinical Protocols; Disease Models, Animal

1992
Morbidity and mortality with outpatient anesthesia: the Massachusetts experience.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1992, Volume: 50, Issue:7

    Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intraveno

1992
Fibreoptic bronchoscopy without general anaesthetic.
    Archives of disease in childhood, 1991, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Local; Bronchoscopes; Bronchoscopy; Child; Child, Preschool; Consciou

1991
Immediate reversal of severe laryngospasm by intranasally instilled lidocaine with epinephrine.
    Annals of emergency medicine, 1985, Volume: 14, Issue:3

    Topics: Administration, Intranasal; Child; Drug Therapy, Combination; Epinephrine; Female; Humans; Laryngism

1985
A comparison of different concentrations of lignocaine hydrochloride used for topical anaesthesia of the larynx of the cat.
    Anaesthesia and intensive care, 1985, Volume: 13, Issue:2

    Topics: Anesthesia, Local; Animals; Cats; Electromyography; Female; Laryngeal Muscles; Laryngismus; Larynx;

1985
Intravenous diazepam: a helpful adjunct in plastic surgery.
    Plastic and reconstructive surgery, 1971, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Amnesia; Anesthesia, Local; Arrhythmias, Cardiac; Ataxia; Child; Diazepam;

1971
The effects of other drugs on the stimulation of laryngospasm in the cat: atropine; thiopentone, suxamethonium; local analgesics.
    British journal of anaesthesia, 1971, Volume: 43, Issue:2

    Topics: Anesthetics, Local; Animals; Apnea; Atropine; Cats; Laryngismus; Larynx; Lidocaine; Respiration; Suc

1971
Laryngospasm and respiratory changes in the cat produced by mechanical stimulation of the pharynx and respiratory tract: problems of intubation in the cat.
    British journal of anaesthesia, 1971, Volume: 43, Issue:1

    Topics: Anesthesia, General; Anesthesia, Local; Animals; Cats; Decerebrate State; Electromyography; Intubati

1971
Lidocaine with general anesthesia for laryngoscopy.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1968, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthesia, Local; Apnea; Bio

1968