lidocaine has been researched along with Lacerations in 33 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Lacerations: Torn, ragged, mangled wounds.
| Excerpt | Relevance | Reference |
|---|---|---|
| "3) to that provided by conventional lidocaine infiltration for the repair of lacerations." | 9.19 | A non-inferiority randomized controlled trial comparing the clinical effectiveness of anesthesia obtained by application of a novel topical anesthetic putty with the infiltration of lidocaine for the treatment of lacerations in the emergency department. ( Jenkins, MG; Little, C; McCarron, PA; McDonald, J; Murphy, DJ, 2014) |
| "Treating minor lacerations with lidocaine-epinephrine-tetracaine before wound closure with tissue adhesive reduced ratings of pain and increased the proportion of pain-free repairs among children aged 3 months to 17 years." | 9.17 | Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial. ( Duncan, MJ; Harman, S; Petrcich, W; Ying, Y; Zemek, R, 2013) |
| "To determine the effectiveness of lidocaine-adrenaline-tetracaine (LAT) in providing adequate anesthesia for the repair of finger lacerations and to monitor the risk of digital ischemia following application of LAT gel to finger lacerations." | 9.11 | The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations. ( Bergholte, J; Brousseau, DC; Hennes, H; Kim, MK; White, NJ, 2004) |
| "To estimate the efficacy of lidocaine ointment in relieving pain after a vaginal delivery with an episiotomy or perineal laceration." | 9.10 | Randomized trial of lidocaine ointment versus placebo for the treatment of postpartum perineal pain. ( Jazayeri, A; Minassian, VA; Prien, SD; Stumbo, K; Timmons, RL, 2002) |
| "Lidocaine infiltration was performed if any sign of pain was observed." | 7.71 | [Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)]. ( Alió Y Sanz, JL; Chipont Benabent, E; García-Hermosa, P, 2001) |
| " The purpose of this study was to measure the effect of hydrocodone/acetaminophen elixir in reducing both pain and anxiety in children undergoing sutured laceration repair in the emergency department." | 5.34 | Evaluation of Hydrocodone/Acetaminophen for Pediatric Laceration Repair: A Randomized Trial. ( Camp, EA; Caviness, AC; Chumpitazi, CE; Grawe, GH; Shah, MI, 2020) |
| "Treating minor lacerations with lidocaine-epinephrine-tetracaine before wound closure with tissue adhesive reduced ratings of pain and increased the proportion of pain-free repairs among children aged 3 months to 17 years." | 5.17 | Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial. ( Duncan, MJ; Harman, S; Petrcich, W; Ying, Y; Zemek, R, 2013) |
| "Topical lidocaine and epinephrine "sequential layered application" is an effective, safe, and less painful method of anesthesia for a wide variety of lacerations." | 5.12 | Expanding the use of topical anesthesia in wound management: sequential layered application of topical lidocaine with epinephrine. ( Gaufberg, SV; Walta, MJ; Workman, TP, 2007) |
| "To determine the effectiveness of lidocaine-adrenaline-tetracaine (LAT) in providing adequate anesthesia for the repair of finger lacerations and to monitor the risk of digital ischemia following application of LAT gel to finger lacerations." | 5.11 | The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations. ( Bergholte, J; Brousseau, DC; Hennes, H; Kim, MK; White, NJ, 2004) |
| "To estimate the efficacy of lidocaine ointment in relieving pain after a vaginal delivery with an episiotomy or perineal laceration." | 5.10 | Randomized trial of lidocaine ointment versus placebo for the treatment of postpartum perineal pain. ( Jazayeri, A; Minassian, VA; Prien, SD; Stumbo, K; Timmons, RL, 2002) |
| " Supplemental lidocaine was then infiltrated through the wound edges and the pain of infiltration was recorded by the patient (or guardian) on a 100-mm visual analog scale marked "most pain" at the high end." | 5.09 | LET versus EMLA for pretreating lacerations: a randomized trial. ( Singer, AJ; Stark, MJ, 2001) |
| "A randomized, prospective, double-blind study comparing benzyl alcohol with epinephrine, 1:100,000 (BA), and lidocaine with epinephrine, 1:100,000 (LID), as local anesthetics was carried out on adult patients with simple lacerations." | 5.09 | Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine. ( Bartfield, JM; Lai, SY; May-Wheeling, HE; Raccio-Robak, N, 2001) |
| "The literature has shown that the induction of anaesthesia in lacerations has remained largely unchanged over the past few years, with lidocaine infiltration still the preferred method." | 4.85 | The use of topical anaesthesia during repair of minor lacerations in Departments of Emergency Medicine: a literature review. ( Jenkins, MG; Kelly, OJ; Little, C; McCarron, P; Murphy, D, 2009) |
| "LAT (lidocaine, adrenaline, and tetracaine) gel is a topical anesthetic that can be applied on lacerations before suturing." | 3.85 | LAT gel for laceration repair in the emergency department: not only for children? ( de Cock, P; Lemoyne, S; van de Voorde, P; van der Gucht, A; Vandamme, E, 2017) |
| "Lidocaine infiltration was performed if any sign of pain was observed." | 3.71 | [Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)]. ( Alió Y Sanz, JL; Chipont Benabent, E; García-Hermosa, P, 2001) |
| " Skin lacerations are common in children and their repair is a very unpleasant experience for a child." | 1.56 | Lidocaine-Epinephrine-Tetracaine Gel Is More Efficient than Eutectic Mixture of Local Anesthetics and Mepivacaine Injection for Pain Control during Skin Repair in Children: A Prospective, Propensity Score Matched Two-Center Study. ( Boettcher, J; Boettcher, M; Königs, I; Reinshagen, K; Wenskus, J, 2020) |
| " Plasma sample analysis was carried out by employing liquid chromatography coupled with tandem mass spectrometric (LC-MS/MS) method, and the pharmacokinetic analysis of the mouse plasma samples was estimated by standard non-compartmental methods." | 1.38 | A pharmacokinetic study of a topical anesthetic (EMLA® ) in mouse soft tissue laceration. ( Al-Musawi, A; Andersson, L; Kombian, SB; Matar, K, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (42.42) | 29.6817 |
| 2010's | 14 (42.42) | 24.3611 |
| 2020's | 5 (15.15) | 2.80 |
| Authors | Studies |
|---|---|
| Siembieda, J | 1 |
| Heyming, T | 1 |
| Padlipsky, P | 1 |
| Young, KD | 1 |
| Scribner-O'Pray, M | 1 |
| Taylor, ED | 1 |
| Krause, E | 1 |
| Nickel, A | 1 |
| Bergmann, KR | 1 |
| Königs, I | 1 |
| Wenskus, J | 1 |
| Boettcher, J | 1 |
| Reinshagen, K | 1 |
| Boettcher, M | 1 |
| Chumpitazi, CE | 1 |
| Caviness, AC | 1 |
| Grawe, GH | 1 |
| Camp, EA | 1 |
| Shah, MI | 1 |
| Jones, A | 1 |
| Kelly, E | 1 |
| Borumandi, F | 1 |
| Martin, HA | 1 |
| Farahmand, S | 1 |
| Hamrah, H | 1 |
| Arbab, M | 1 |
| Sedaghat, M | 1 |
| Basir Ghafouri, H | 1 |
| Bagheri-Hariri, S | 1 |
| Lambert, C | 1 |
| Goldman, RD | 1 |
| Harman, S | 1 |
| Zemek, R | 1 |
| Duncan, MJ | 1 |
| Ying, Y | 1 |
| Petrcich, W | 1 |
| Jenkins, MG | 2 |
| Murphy, DJ | 1 |
| Little, C | 2 |
| McDonald, J | 1 |
| McCarron, PA | 1 |
| Wang, B | 1 |
| Hill, VK | 1 |
| Wilson, MH | 1 |
| Felstead, AM | 1 |
| Sherman, JM | 1 |
| Sheppard, P | 1 |
| Hoppa, E | 1 |
| Krief, W | 1 |
| Avarello, J | 1 |
| Vandamme, E | 1 |
| Lemoyne, S | 1 |
| van der Gucht, A | 1 |
| de Cock, P | 1 |
| van de Voorde, P | 1 |
| Şener, A | 2 |
| Demircan, A | 1 |
| Keleş, A | 1 |
| Bildik, F | 1 |
| Karakurt, K | 1 |
| Al-Musawi, A | 2 |
| Matar, K | 2 |
| Kombian, S | 1 |
| Andersson, L | 4 |
| Okur, OM | 1 |
| Kavakli, HŞ | 1 |
| Çelik, GK | 1 |
| Doğan, NÖ | 1 |
| Içme, F | 1 |
| Günaydin, GP | 1 |
| Kelly, OJ | 1 |
| Murphy, D | 1 |
| McCarron, P | 1 |
| Musawi, AA | 1 |
| McNulty, RJ | 1 |
| Handley, TP | 1 |
| Devlin, MF | 1 |
| Kombian, SB | 1 |
| Minassian, VA | 1 |
| Jazayeri, A | 1 |
| Prien, SD | 1 |
| Timmons, RL | 1 |
| Stumbo, K | 1 |
| Priestley, S | 1 |
| Kelly, AM | 1 |
| Chow, L | 1 |
| Powell, C | 1 |
| Williams, A | 1 |
| Karcioglu, O | 1 |
| Topacoglu, H | 1 |
| Ayrik, C | 1 |
| Ozucelik, DN | 1 |
| Soysal, S | 1 |
| Adriansson, C | 1 |
| Suserud, BO | 1 |
| Bergbom, I | 1 |
| White, NJ | 1 |
| Kim, MK | 1 |
| Brousseau, DC | 1 |
| Bergholte, J | 1 |
| Hennes, H | 1 |
| Gaufberg, SV | 1 |
| Walta, MJ | 1 |
| Workman, TP | 1 |
| Al-Asfour, A | 1 |
| Al-Melh, M | 1 |
| Joseph, B | 1 |
| Singer, AJ | 2 |
| Stark, MJ | 2 |
| Van-Liaw, P | 1 |
| Chipont Benabent, E | 1 |
| García-Hermosa, P | 1 |
| Alió Y Sanz, JL | 1 |
| Kalghatgi, S | 1 |
| Bartfield, JM | 1 |
| May-Wheeling, HE | 1 |
| Raccio-Robak, N | 1 |
| Lai, SY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of 2 Application Techniques for LET (Lidocaine 4%; Epinephrine 0.1%; Tetracaine 0.5%) Gel Used Prior to Simple Laceration Repair in Children[NCT04203225] | Phase 4 | 48 participants (Actual) | Interventional | 2017-05-22 | Completed | ||
| Comparison of 2 Application Techniques for LET (Lidocaine 4%; Epinephrine 0.1%; Tetracaine 0.5%) Gel Used Prior to Simple Laceration Repair[NCT04536493] | Phase 4 | 48 participants (Actual) | Interventional | 2019-06-19 | Completed | ||
| Traditional Dorsal Digital Block vs Volar Subcutaneous Digital Block[NCT05280704] | 150 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | |||
| The Effect of Sonophoresis on Topical Anesthesia: a Clinical Trial[NCT01283490] | Phase 1 | 50 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| Prospective Evaluation of Topical Analgesia Using a Lidocaine/Prilocaine Cream for Laceration Repair in the Emergency Department[NCT03071601] | Phase 4 | 132 participants (Actual) | Interventional | 2017-12-01 | Completed | ||
| Randomized Double Blind Clinical Trial on the Effect of Levobupivacaine Infiltration Versus Placebo on the Post Partum Perineal Pain in Episiotomy in Primiparous Women After Instrumental Delivery[NCT02796547] | Phase 2 | 0 participants (Actual) | Interventional | 2016-07-14 | Withdrawn (stopped due to Lack of human ressources) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Need for additional infiltrated local anesthetic (lidocaine) (NCT04203225)
Timeframe: At any time during suturing procedure, time frame is duration of procedure, generally 10-20 minutes, less than one hour. Determined by chart review immediately after procedure completion.
| Intervention | Participants (Count of Participants) |
|---|---|
| Single LET | 4 |
| Triple LET | 5 |
Pain score self-rated by patient on 100m Visual Analog Pain scale, minimum value 0, maximum value 100, higher scores equal more pain (worse outcome) (NCT04203225)
Timeframe: Immediately on placement or attempt at placement of first suture
| Intervention | mm (Mean) |
|---|---|
| Single LET | 16 |
| Triple LET | 16 |
2 reviews available for lidocaine and Lacerations
| Article | Year |
|---|---|
Factors Associated With Low Procedural Pain Scores Among 1- to 5-Year-Old Patients Undergoing Facial Laceration Repair.
Topics: Anti-Anxiety Agents; Child, Preschool; Epinephrine; Humans; Infant; Lacerations; Lidocaine; Pain; Pa | 2023 |
The use of topical anaesthesia during repair of minor lacerations in Departments of Emergency Medicine: a literature review.
Topics: Administration, Topical; Anesthetics, Local; Cocaine; Drug Combinations; Epinephrine; Humans; Lacera | 2009 |
16 trials available for lidocaine and Lacerations
| Article | Year |
|---|---|
Triple Versus Single Application of Lidocaine, Epinephrine, and Tetracaine for Laceration Repair in Children.
Topics: Adolescent; Child; Epinephrine; Humans; Lacerations; Lidocaine; Single-Blind Method; Tetracaine | 2022 |
Evaluation of Hydrocodone/Acetaminophen for Pediatric Laceration Repair: A Randomized Trial.
Topics: Acetaminophen; Administration, Topical; Adolescent; Age Factors; Anxiety; Child; Child, Preschool; D | 2020 |
Pain management of acute limb trauma patients with intravenous lidocaine in emergency department.
Topics: Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Local; Arm Injuries | 2018 |
Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Child; Child, Preschool; Drug Combination | 2013 |
A non-inferiority randomized controlled trial comparing the clinical effectiveness of anesthesia obtained by application of a novel topical anesthetic putty with the infiltration of lidocaine for the treatment of lacerations in the emergency department.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lacerations; Lidocai | 2014 |
Comparison of local infiltration anesthesia and peripheral nerve block: a randomized prospective study in hand lacerations.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Female; Hand; Humans; Lacerations; L | 2015 |
Two injection digital block versus single subcutaneous palmar injection block for finger lacerations.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Drug Administration Schedule; Emergency Service, | 2017 |
Randomized trial of lidocaine ointment versus placebo for the treatment of postpartum perineal pain.
Topics: Administration, Topical; Adult; Analysis of Variance; Anesthetics, Local; Double-Blind Method; Episi | 2002 |
Application of topical local anesthetic at triage reduces treatment time for children with lacerations: a randomized controlled trial.
Topics: Anesthesia, Local; Child; Child, Preschool; Double-Blind Method; Emergency Service, Hospital; Epinep | 2003 |
Prilocaine versus plain or buffered lidocaine for local anesthesia in laceration repair: randomized double-blind comparison.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Double-Blind Method; Female; Humans; Lacerations; Lidoc | 2003 |
The use of topical anaesthesia at children's minor lacerations: an experimental study.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Female; | 2004 |
The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations.
Topics: Anesthesia, Local; Anesthetics, Local; Child; Drug Therapy, Combination; Epinephrine; Female; Finger | 2004 |
Expanding the use of topical anesthesia in wound management: sequential layered application of topical lidocaine with epinephrine.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Dose-Response Relationship, Drug; Dr | 2007 |
Pretreatment of lacerations with lidocaine, epinephrine, and tetracaine at triage: a randomized double-blind trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Child; Chil | 2000 |
LET versus EMLA for pretreating lacerations: a randomized trial.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Female; Humans; | 2001 |
Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine.
Topics: Adult; Anesthetics, Local; Benzyl Alcohol; Double-Blind Method; Epinephrine; Female; Humans; Lacerat | 2001 |
15 other studies available for lidocaine and Lacerations
| Article | Year |
|---|---|
Lidocaine-Epinephrine-Tetracaine Gel Is More Efficient than Eutectic Mixture of Local Anesthetics and Mepivacaine Injection for Pain Control during Skin Repair in Children: A Prospective, Propensity Score Matched Two-Center Study.
Topics: Administration, Topical; Anesthetics, Combined; Child; Epinephrine; Female; Gels; Humans; Laceration | 2020 |
The Role of Topical Anesthetics in the Treatment of Pediatric Facial Lacerations.
Topics: Anesthesia, Local; Anesthetics, Local; Child; Epinephrine; Humans; Lacerations; Lidocaine; Tetracain | 2021 |
The Power of Lidocaine, Epinephrine, and Tetracaine (LET) and a Child Life Specialist When Suturing Lacerations in Children.
Topics: Anesthetics, Local; Child; Drug Combinations; Epinephrine; Gels; Humans; Lacerations; Lidocaine; Ped | 2017 |
Pain management for children needing laceration repair.
Topics: Administration, Cutaneous; Anesthetics, Local; Child; Drug Combinations; Epinephrine; Humans; Lacera | 2018 |
LAT gel, a powerful tool underused in the repair of paediatric lacerations.
Topics: Anesthetics, Local; Child; Debridement; Drug Combinations; Emergency Service, Hospital; Epinephrine; | 2014 |
Let Us Use LET: A Quality Improvement Initiative.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Child; Drug Combinations; Emerge | 2016 |
LAT gel for laceration repair in the emergency department: not only for children?
Topics: Administration, Topical; Adult; Anesthetics, Local; Emergency Service, Hospital; Epinephrine; Female | 2017 |
Blood concentration of prilocaine and lidocaine after the use of topical anesthesia (Oraqix
Topics: Anesthesia; Anesthetics, Local; Animals; Lacerations; Lidocaine; Lidocaine, Prilocaine Drug Combinat | 2016 |
Use of topical as only anesthetic for suturing a traumatic facial laceration.
Topics: Adult; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cheek; Eyelids; Facial Injuries | 2010 |
Reducing the need for general anaesthesia in children: use of LAT gel in treating facial lacerations.
Topics: Administration, Topical; Anesthesia, General; Anesthesia, Local; Anesthetics, Combined; Anesthetics, | 2013 |
A pharmacokinetic study of a topical anesthetic (EMLA® ) in mouse soft tissue laceration.
Topics: Anesthetics, Local; Animals; Area Under Curve; Chromatography, Liquid; Lacerations; Lidocaine; Lidoc | 2012 |
Healing pattern of experimental soft tissue lacerations after application of novel topical anesthetic agents - an experimental study in rabbits.
Topics: Anesthetics, Combined; Anesthetics, Local; Animals; Gels; Lacerations; Lidocaine; Lidocaine, Priloca | 2008 |
Resident's column: Use of topical anesthetics in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Chin; Female; Humans; Infant; Injections, Subcutaneou | 2001 |
[Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)].
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Child; Child, Preschool; Dermatologic Surgical Procedur | 2001 |
Just the berries. Allergy to local anesthetics.
Topics: Aged; Anesthetics, Local; Drug Hypersensitivity; Humans; Lacerations; Lidocaine; Male; Skin Test End | 2001 |