lidocaine has been researched along with Labor Pain in 4 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Labor Pain: Pain associated with OBSTETRIC LABOR in CHILDBIRTH. It is caused primarily by UTERINE CONTRACTION as well as pressure on the CERVIX; BLADDER; and the GASTROINTESTINAL TRACT. Labor pain mostly occurs in the ABDOMEN; the GROIN; and the BACK.
Excerpt | Relevance | Reference |
---|---|---|
"The primary long-term outcome was backache occurring within 3 months of the birth persisting for longer than 6 weeks." | 2.76 | Long-term effects of epidural analgesia in labor: a randomized controlled trial comparing high dose with two mobile techniques. ( Lancashire, RJ; MacArthur, C; Moore, PA; Shennan, A; Wilson, MJ, 2011) |
"Horner's syndrome is a rare complication of epidural analgesia for labor." | 1.34 | Trigeminal nerve palsy and Horner's syndrome following epidural analgesia for labor: a subdural block? ( Avellanal, M; Baticón, P; De la Gala, F; González-Zarco, LM; Reyes, A, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (75.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Wilson, MJ | 1 |
Moore, PA | 1 |
Shennan, A | 1 |
Lancashire, RJ | 1 |
MacArthur, C | 1 |
Edelman, A | 1 |
Nichols, MD | 1 |
Leclair, C | 1 |
Jensen, JT | 1 |
De la Gala, F | 1 |
Reyes, A | 1 |
Avellanal, M | 1 |
Baticón, P | 1 |
González-Zarco, LM | 1 |
Pongrojpaw, D | 1 |
Somprasit, C | 1 |
Chanthasenanont, A | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion[NCT01330459] | Phase 4 | 121 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
A Comparison of Intrauterine Lidocaine Infusion and Paracervical Block for Pain Management in First Trimester Abortions[NCT00613821] | 80 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366] | Phase 4 | 121 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
Double Blind, Randomized, Prospective Trial of Impact of Pain Scores on Intrauterine Lidocaine vs Normal Saline Infusion Before IUD Placement.[NCT01311102] | Phase 4 | 40 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
To assess need for additional intraoperative and/or postoperative pain medication (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
Intervention | Participants (Count of Participants) |
---|---|
Hydrocodone/Acetaminophen | 0 |
Placebo | 0 |
To determine whether HC/APAP, given in addition to a standard regimen of ibuprofen, lorazepam, and PCB, affects patient pain perception at the time of uterine aspiration, as measured by distance (mm) from the left of the 100 mm visual analog scale (VAS). The number 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: At time of uterine aspiration (baseline)
Intervention | mm (Mean) |
---|---|
Hydrocodone/Acetaminophen | 65.7 |
Placebo | 63.1 |
Distance (mm) from the left of the 100 mm VAS scale (VAS anchors: 0 = none, 100 mm = worst imaginable) recorded after cervical dilation (NCT01330459)
Timeframe: During procedure (approximately 45-90 min after hydrocodone/acetaminophen or placebo, and within 5 minutes of procedure starting)
Intervention | mm (Mean) |
---|---|
Hydrocodone/Acetaminophen | 47.2 |
Placebo | 43.9 |
To assess whether HC/APAP is associated with nausea, measured on the 100 mm VAS, recorded 30 minutes postoperatively. VAS anchors: 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
Intervention | mm (Mean) |
---|---|
Hydrocodone/Acetaminophen | 19.4 |
Placebo | 11.4 |
Distance (mm) from the left of the 100 mm VAS (VAS anchors: 0 = unsatisfied, 100 mm = very satisfied) recorded 30 minutes after completion of the procedure. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
Intervention | mm (Mean) |
---|---|
Hydrocodone/Acetaminophen | 74.8 |
Placebo | 67.3 |
Subjects perception of pain is measured using a 100mm visual analog scale (VAS).The 100mm Pain Visual Analog Scale (VAS) is an instrument used to capture subjective attitudes that cannot be directly measured. When responding to a VAS item, respondents specify their level of pain by indicating a position along a 100mm continues line: pain scores can range from 0 (no pain) to 100 (worst pain imaginable). (NCT00613821)
Timeframe: Immediately (time zero) at uterine aspiration
Intervention | mm (Mean) |
---|---|
Lidocaine Infusion | 71 |
Paracervical Block Only | 43 |
"IUD was inserted following the manufacturer's instructions, and a pain score was immediately obtained. Pain was scored on 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Immediately after IUD placement
Intervention | units on a scale of 0-9 (Mean) |
---|---|
Lidocaine | 2.95 |
Normal Saline | 3.68 |
"Pain score on 0-9 scale for tenaculum placement (without anesthesia); with 0 being no pain and 9 being worst pain in life. Taken to adjust for different pain thresholds among subjects" (NCT01311102)
Timeframe: Immediately following tenaculum placement
Intervention | units on a scale of 0-9 (Mean) |
---|---|
Lidocaine | 2.20 |
Normal Saline | 2.70 |
"After liquid infused into three parts of the endometrial cavity: in the lower one third, the middle, and at the top of the cavity. Pain was scored on a 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Recorded at the end of the infusion
Intervention | units on a scale of 0-9 (Mean) |
---|---|
Lidocaine | 2.50 |
Normal Saline | 3.39 |
"Pain score on 0-9 scale obtained just before the patient left the examination room; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Before patient left the examination room at conclusion of procedure
Intervention | units on a scale of 0-9 (Mean) |
---|---|
Lidocaine | 2.12 |
Normal Saline | 1.73 |
3 trials available for lidocaine and Labor Pain
Article | Year |
---|---|
Long-term effects of epidural analgesia in labor: a randomized controlled trial comparing high dose with two mobile techniques.
Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthetics, Local; Back Pain; Bupivacaine; Fec | 2011 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2006 |
The efficacy of lidocaine-prilocaine cream to reduce pain in genetic amniocentesis.
Topics: Adult; Amniocentesis; Anesthetics, Local; Female; Humans; Labor Pain; Lidocaine; Pain Measurement; P | 2007 |
1 other study available for lidocaine and Labor Pain
Article | Year |
---|---|
Trigeminal nerve palsy and Horner's syndrome following epidural analgesia for labor: a subdural block?
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local; Bu | 2007 |