Page last updated: 2024-10-28

lidocaine and Kidney Failure, Chronic

lidocaine has been researched along with Kidney Failure, Chronic in 39 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"We encountered a case of malignant hyperthermia caused by intravenous lidocaine which had been administered as treatment for a ventricular arrhythmia."7.68Malignant hyperthermia caused by intravenous lidocaine for ventricular arrhythmia. ( Ida, K; Inoue, M; Katoh, S; Kondoh, M; Okuda, J; Tatsukawa, H; Terashima, S, 1992)
"We report a patient with chronic renal failure and ischemic heart disease who developed clinically significant methemoglobinemia after an axillary block with bupivacaine and additional injection of lidocaine in the operative field."5.30Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field. ( Dieterich, HJ; Mühlbauer, B; Schroeder, TH, 1999)
"Hyperbilirubinemia, which frequently occurs in severe liver disease, interferes with the fluorescence polarization immunoassay (FPIA) monoethylglycinexylidide (MEGX) assay manufactured by Abbott Diagnostics."3.70Determination of monoethylglycinexylidide by fluorescence polarization immunoassay in highly icteric serum samples: modified precipitation procedure and HPLC compared. ( Armstrong, VW; Niedmann, PD; Oellerich, M; Schütz, E; Shipkova, M; Wieland, E, 1998)
"We encountered a case of malignant hyperthermia caused by intravenous lidocaine which had been administered as treatment for a ventricular arrhythmia."3.68Malignant hyperthermia caused by intravenous lidocaine for ventricular arrhythmia. ( Ida, K; Inoue, M; Katoh, S; Kondoh, M; Okuda, J; Tatsukawa, H; Terashima, S, 1992)
"The plasma protein binding of diazepam and lidocaine was measured in patients with renal disease (those with uremia, nephrotic syndrome, or who had received a transplant) and in age- and sex- matched control subjects."3.66Diazepam and lidocaine plasma protein binding in renal disease. ( Davis, D; Grossman, SH; Kitchell, BB; Routledge, PA; Shand, DG, 1982)
"Time to postoperative pain initiation, need for postoperative pain killers was significantly better in Group II as compared with the Group I."2.80INFLUENCE OF TYPE OF ANESTHESIA ON HEMODYNAMIC PARAMETERS AND OUTCOME OF DIALYSIS ARTERIOVENOUS FISTULA OPERATIONS. ( Beglarishvili, L; Chkhotua, A; Managadze, L; Shoshiashvili, V; Tataradze, A, 2015)
"001), and half-life was approximately doubled (4."2.72Differential effect of chronic renal failure on the pharmacokinetics of lidocaine in patients receiving and not receiving hemodialysis. ( Bertoli, M; De Martin, S; Orlando, R; Palatini, P; Pegoraro, P, 2006)
"Twenty-eight adult chronic renal failure patients (ASA physical status III) scheduled for arteriovenous fistula construction were studied in a prospective, randomized, double-blind, controlled design."2.71Clonidine as an adjuvant for lidocaine in axillary brachial plexus block in patients with chronic renal failure. ( Adnan, T; Ayşe, K; Elif, AA; Gülnaz, A, 2005)
"Children with chronic renal failure are frequently exposed to painful invasive procedures."2.68Topical anaesthesia in haemodialysis: evaluation of topical anaesthesia with lidocaine during vascular access in children undergoing long-term haemodialysis for chronic renal failure. ( Ay, N; Kavukçu, S; Sersan, R; Sevinç, N; Soylu, A; Türkmen, M, 1997)
"Pain was assessed using a visual analogue scale, a verbal descriptive scale and a direct comparison between paired treatments."2.67Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help? ( Coulthard, MG; Hardy, SP; Hughes, C; Matthews, JN; Morris, KP, 1994)
"A patient developed anaphylactic shock after a heparin dosage during an operation to make inner shunt for chronic renal failure of Alport syndrome."1.35[Case of anosmia which appeared after anaphylactic shock due to intravenous heparin]. ( Ishikawa, S; Kobinata, H; Makita, K; Nakazawa, K; Uchida, T; Yamamoto, M, 2009)
"Appropriate dosing of pilsicainide hydrochloride, an anti-arrhythmic drug excreted via the kidney, was investigated in patients on dialysis."1.31Appropriate dosing of pilsicainide hydrochloride in patients on hemodialysis. ( Fujii, Z; Fujimoto, K; Kawata, Y; Matsumoto, M; Matsuzaki, M; Minami, M; Nawata, C; Sakumura, T, 2001)
"We report a patient with chronic renal failure and ischemic heart disease who developed clinically significant methemoglobinemia after an axillary block with bupivacaine and additional injection of lidocaine in the operative field."1.30Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field. ( Dieterich, HJ; Mühlbauer, B; Schroeder, TH, 1999)
" Cmax plasma levels for normal patients (5."1.28Interscalene brachial plexus blockade with lidocaine in chronic renal failure--a pharmacokinetic study. ( Cunningham, AJ; McEllistrem, RF; O'Malley, K; O'Toole, D; Schell, J, 1989)
" The findings are used to suggest a safe dosage regimen."1.27Pharmacokinetics of tocainide in patients with severe renal failure. ( Braun, J; Engelmaier, F; Gessler, U; Gluth, WP; Sörgel, F, 1985)
"3 ml/min/kg), terminal half-life (148 min), and total volume of distribution (1."1.25Pharmacokinetics and metabolism of lidocaine in patients with renal failure. ( Atkinson, AJ; Collinsworth, KA; Harrison, DC; Perlroth, F; Strong, JM; Winkle, RA, 1975)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199018 (46.15)18.7374
1990's7 (17.95)18.2507
2000's8 (20.51)29.6817
2010's6 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pınar, HU1
Berna, C1
Luthy, C1
Samer, CF1
Spechbach, H1
Pautex, S1
Piguet, V1
Macfarlane, AJ1
Kearns, RJ1
Aitken, E1
Kinsella, J1
Clancy, MJ1
Shoshiashvili, V1
Tataradze, A1
Beglarishvili, L1
Managadze, L1
Chkhotua, A1
Pongraweewan, O1
Inchua, N1
Kitsiripant, C1
Kongmuang, B1
Tiwirach, W1
Kobinata, H1
Yamamoto, M1
Ishikawa, S1
Uchida, T1
Nakazawa, K1
Makita, K1
Al-mustafa, MM1
Massad, I1
Alsmady, M1
Al-qudah, A1
Alghanem, S1
Hiasa, G1
Okayama, H1
Nishimura, K1
Sumimoto, T1
Adnan, T1
Elif, AA1
Ayşe, K1
Gülnaz, A1
Fuhrmeister, J1
Janelle, J1
Zhang, RV1
De Martin, S1
Orlando, R2
Bertoli, M2
Pegoraro, P1
Palatini, P2
Dhir, S1
Fuller, J1
Urban, BJ1
McDonald, HP1
Steen, SN1
Rooke, NT1
Milne, B1
Grossman, SH1
Davis, D1
Kitchell, BB1
Shand, DG1
Routledge, PA1
Gramatikova, R1
Ianev, Ia1
Panchev, P1
Vitanova, S1
Morris, KP1
Hughes, C1
Hardy, SP1
Matthews, JN1
Coulthard, MG1
Alon, US1
Allen, S1
Rameriz, Z1
Warady, BA1
Kaplan, RA1
Harris, DJ1
Türkmen, M1
Kavukçu, S1
Soylu, A1
Ay, N1
Sevinç, N1
Sersan, R1
Schütz, E1
Shipkova, M1
Niedmann, PD1
Wieland, E1
Armstrong, VW1
Oellerich, M1
Schroeder, TH1
Dieterich, HJ1
Mühlbauer, B1
Floreani, M1
Padrini, R1
Piccoli, P1
Calò, L1
Matsumoto, M1
Fujii, Z1
Kawata, Y1
Sakumura, T1
Minami, M1
Fujimoto, K1
Nawata, C1
Matsuzaki, M1
Tapia, L1
Dhingra, RC1
Rosen, KM1
Vaziri, ND1
Saiki, JK1
Hughes, W1
Lowenthal, DT1
Collinsworth, KA1
Strong, JM1
Atkinson, AJ1
Winkle, RA1
Perlroth, F1
Harrison, DC1
Tatsukawa, H1
Okuda, J1
Kondoh, M1
Inoue, M1
Terashima, S1
Katoh, S1
Ida, K1
Owada, S1
Toyama, K1
Maeba, T1
Ishida, M1
Doherty, JE1
McEllistrem, RF1
Schell, J1
O'Malley, K1
O'Toole, D1
Cunningham, AJ1
Sedman, AJ1
Molitoris, BA1
Nakata, LM1
Gal, J1
Martin, R1
Beauregard, L1
Tétrault, JP1
Braun, J1
Sörgel, F1
Engelmaier, F1
Gluth, WP1
Gessler, U1
Thomson, PD2
Melmon, KL2
Richardson, JA1
Cohn, K1
Steinbrunn, W1
Cudihee, R1
Rowland, M2
Kipka, EH1
Kacki, J1
Mayzner, E1
Zawadzki, A1
Siedlecki, J1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Regional Compared to Local Anaesthesia Influence Outcome After Arteriovenous Fistula Creation?[NCT01706354]126 participants (Anticipated)Interventional2012-10-31Recruiting
Comparison Between Bupivacaine 0.5% Versus Bupivacaine 0.25% Plus Lidocaine 1% in Ultrasound-guided Infraclavicular Block: a Prospective Randomized Controlled Trial[NCT05834023]Phase 440 participants (Anticipated)Interventional2023-05-02Recruiting
Effect of Epinephrine on Systemic Absorption of Mepivacaine Administered for Brachial Plexus Block in Patients With Chronic Renal Insufficiency[NCT01533545]16 participants (Actual)Interventional2012-09-30Terminated (stopped due to Slow recruitment)
Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573]Phase 131 participants (Actual)Interventional2004-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lidocaine and Kidney Failure, Chronic

ArticleYear
Clinical use of digitalis glycosides. An update.
    Cardiology, 1985, Volume: 72, Issue:5-6

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Age Factors; Anti-Arrhythmia Agents; Antihyperten

1985

Trials

8 trials available for lidocaine and Kidney Failure, Chronic

ArticleYear
Does regional compared to local anaesthesia influence outcome after arteriovenous fistula creation?
    Trials, 2013, Aug-19, Volume: 14

    Topics: Adrenergic Agonists; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Arteriovenous Shu

2013
INFLUENCE OF TYPE OF ANESTHESIA ON HEMODYNAMIC PARAMETERS AND OUTCOME OF DIALYSIS ARTERIOVENOUS FISTULA OPERATIONS.
    Georgian medical news, 2015, Issue:249

    Topics: Age Factors; Aged; Anesthesia, Local; Anesthetics, Local; Arteriovenous Fistula; Blood Flow Velocity

2015
Onset Time of 2% Lidocaine and 0.5% Bupivacaine Mixture versus 0.5% Bupivacaine Alone using Ultrasound and Double Nerve Stimulation for Infraclavicular Brachial Plexus Anesthesia in ESRD Patients Undergoing Arteriovenous Fistula Creation.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2016, Volume: 99, Issue:5

    Topics: Adult; Anesthetics, Local; Arteriovenous Shunt, Surgical; Brachial Plexus Block; Bupivacaine; Double

2016
Clonidine as an adjuvant for lidocaine in axillary brachial plexus block in patients with chronic renal failure.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:4

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Aged; Anastomosis, Surgical; Anesthetics, Local; B

2005
Differential effect of chronic renal failure on the pharmacokinetics of lidocaine in patients receiving and not receiving hemodialysis.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:6

    Topics: Area Under Curve; Biotransformation; Half-Life; Humans; Kidney Failure, Chronic; Lidocaine; Male; Me

2006
Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:9

    Topics: Adult; Aged; Anemia; Anesthetics, Local; Double-Blind Method; Drug Combinations; Erythropoietin; Fem

1994
Lidocaine for the alleviation of pain associated with subcutaneous erythropoietin injection.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Cross-Over Studies; Erythropoietin; Female; Hematocrit; Humans;

1994
Topical anaesthesia in haemodialysis: evaluation of topical anaesthesia with lidocaine during vascular access in children undergoing long-term haemodialysis for chronic renal failure.
    International journal of nursing practice, 1997, Volume: 3, Issue:2

    Topics: Administration, Topical; Adolescent; Anesthetics, Local; Catheters, Indwelling; Child; Double-Blind

1997

Other Studies

30 other studies available for lidocaine and Kidney Failure, Chronic

ArticleYear
Tremor on the same extremity after axillary brachial plexus block.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2019, Volume: 31, Issue:3

    Topics: Anesthetics, Local; Arteriovenous Fistula; Brachial Plexus Block; Diagnosis, Differential; Female; H

2019
[Efficient treatment of breakthrough pain in adults: the importance of timing and medication choice].
    Revue medicale suisse, 2013, Jun-26, Volume: 9, Issue:392

    Topics: Administration, Cutaneous; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammato

2013
[Case of anosmia which appeared after anaphylactic shock due to intravenous heparin].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:8

    Topics: Anaphylaxis; Anesthesia, Local; Heparin; Humans; Infusions, Intravenous; Intraoperative Complication

2009
The effect of low serum bicarbonate values on the onset of action of local anesthesia with vertical infraclavicular brachial plexus block in patients with end-stage renal failure.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2010, Volume: 21, Issue:3

    Topics: Adult; Aged; Anesthetics, Combined; Anesthetics, Local; Arteriovenous Shunt, Surgical; Bicarbonates;

2010
Three elderly cases with Brugada-type electrocardiographic pattern unmasked by pilsicainide at the toxic level.
    Internal medicine (Tokyo, Japan), 2005, Volume: 44, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Electrocardiography; Heart Block; Humans; Kidney Fa

2005
Apparent sialadenopathy of the sublingual glands after general anesthesia with placement of laryngeal mask airway.
    Journal of clinical anesthesia, 2005, Volume: 17, Issue:8

    Topics: Adult; Anesthesia, General; Anesthetics, Local; Female; Humans; Kidney Failure, Chronic; Laryngeal M

2005
Case report: pregnancy in hemodialysis-dependent end-stage renal disease: anesthetic considerations.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2007, Volume: 54, Issue:7

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local;

2007
Axillary block and dialysis.
    JAMA, 1967, Mar-20, Volume: 199, Issue:12

    Topics: Adolescent; Adult; Arteriovenous Fistula; Autonomic Nerve Block; Brachial Plexus; Female; Humans; In

1967
Acute pulmonary edema after regional anesthesia with lidocaine and epinephrine in a patient with chronic renal failure.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:3

    Topics: Acute Disease; Adult; Anesthesia, Conduction; Epinephrine; Humans; Kidney Failure, Chronic; Lidocain

1984
Diazepam and lidocaine plasma protein binding in renal disease.
    Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:3

    Topics: Adult; Aged; Blood Proteins; Diazepam; Fatty Acids, Nonesterified; Female; Humans; Kidney Diseases;

1982
[Anesthesia in creating arteriovenous fistulae in chronic kidney failure patients].
    Khirurgiia, 1980, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Anesthesia; Arteriovenous Shunt, Surgical; Droperidol; Drug Combinations; Female;

1980
Determination of monoethylglycinexylidide by fluorescence polarization immunoassay in highly icteric serum samples: modified precipitation procedure and HPLC compared.
    Clinical chemistry, 1998, Volume: 44, Issue:6 Pt 1

    Topics: Chemical Precipitation; Chromatography, High Pressure Liquid; Fluorescence Polarization Immunoassay;

1998
Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:4

    Topics: Acidosis; Alkalies; Anesthetics, Local; Antidotes; Axilla; Bupivacaine; Drug Interactions; Female; H

1999
Effects of chronic renal failure and hemodialysis on the monoethylglycinexylidide liver function test.
    Clinical chemistry, 2000, Volume: 46, Issue:9

    Topics: Humans; Injections, Intravenous; Kidney Failure, Chronic; Lidocaine; Liver Function Tests; Male; Mid

2000
Appropriate dosing of pilsicainide hydrochloride in patients on hemodialysis.
    Nephron, 2001, Volume: 88, Issue:2

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Premature Complexes; Echocardiography; Electroc

2001
Pruritus on hemodialysis.
    International journal of dermatology, 1979, Volume: 18, Issue:3

    Topics: Humans; Kidney Failure, Chronic; Lidocaine; Pruritus; Renal Dialysis

1979
Procainamide and the sinus node.
    Chest, 1979, Volume: 76, Issue:6

    Topics: Aged; Arrhythmia, Sinus; Humans; Kidney Failure, Chronic; Lidocaine; Procainamide; Sinoatrial Node

1979
Clearance of lidocaine by hemodialysis.
    Southern medical journal, 1979, Volume: 72, Issue:12

    Topics: Female; Humans; Kidney Failure, Chronic; Lidocaine; Poisoning; Pruritus; Renal Dialysis

1979
Pharmacokinetics of propranolol, quinidine, procainamide and lidocaine in chronic renal disease.
    The American journal of medicine, 1977, Volume: 62, Issue:4

    Topics: Biotransformation; Dose-Response Relationship, Drug; Humans; Kidney; Kidney Failure, Chronic; Lidoca

1977
Pharmacokinetics and metabolism of lidocaine in patients with renal failure.
    Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:1

    Topics: Computers; Ethylamines; Glycine; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Lidocaine; Xy

1975
Malignant hyperthermia caused by intravenous lidocaine for ventricular arrhythmia.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:8

    Topics: Aged; Aortic Valve Stenosis; Arrhythmias, Cardiac; Humans; Infusions, Intravenous; Kidney Failure, C

1992
[Uremic pruritus in chronic kidney failure with hemodialysis].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Diazepam; Histamine; Histamine Antagonists; Humans; Kidney Failure, Chronic; Lidocaine; Parathyroide

1992
Interscalene brachial plexus blockade with lidocaine in chronic renal failure--a pharmacokinetic study.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:1

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Brachial Plexus; Female; Humans; Kidney Failure, Chronic

1989
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
    American journal of nephrology, 1986, Volume: 6, Issue:2

    Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic;

1986
Brachial plexus blockade and chronic renal failure.
    Anesthesiology, 1988, Volume: 69, Issue:3

    Topics: Analgesia; Brachial Plexus; Epinephrine; Female; Humans; Kidney Failure, Chronic; Lidocaine; Male; N

1988
Pharmacokinetics of tocainide in patients with severe renal failure.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:6

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Female; Half-Life; Hemodynamics; Humans; Kidney Failur

1985
Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans.
    Annals of internal medicine, 1973, Volume: 78, Issue:4

    Topics: Adult; Alcoholism; Blood Proteins; Chromatography, Gas; Female; Half-Life; Heart Failure; Humans; In

1973
[Anesthesia in dialysis-patients].
    Fortschritte der Medizin, 1974, Feb-07, Volume: 92, Issue:4

    Topics: Anesthesia, General; Anesthesia, Local; Humans; Kidney Failure, Chronic; Lidocaine; Procaine; Renal

1974
Brachial plexus block in uremic patients.
    Polish medical journal, 1971, Volume: 10, Issue:2

    Topics: Anesthesia, Local; Anesthesia, Spinal; Arteriovenous Shunt, Surgical; Axilla; Brachial Plexus; Fenta

1971
The influence of heart failure, liver disease, and renal failure on the disposition of lidocaine in man.
    American heart journal, 1971, Volume: 82, Issue:3

    Topics: Arrhythmias, Cardiac; Heart Failure; Humans; Kidney; Kidney Failure, Chronic; Lidocaine; Liver; Live

1971