Page last updated: 2024-10-28

lidocaine and Joint Pain

lidocaine has been researched along with Joint Pain in 32 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The aim of this trial was to assess the relative efficacy of a sage/echinacea spray and a chlorhexidine/lidocaine spray in the treatment of acute sore throats."9.14Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. ( Berger, D; Klein, P; Schapowal, A; Suter, A, 2009)
"199 adults aged ≥40 years with hip osteoarthritis and at least moderate pain: 67 were randomly assigned to receive advice and education (best current treatment (BCT)), 66 to BCT plus ultrasound guided injection of triamcinolone and lidocaine, and 66 to BCT plus ultrasound guided injection of lidocaine."5.51Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial. ( Bromley, K; Cherrington, A; Foster, NE; Hall, A; Hennings, S; Holden, MA; Hughes, E; Hughes, G; Jinks, C; Kigozi, J; Lewis, M; Mallen, CD; Menon, A; Oppong, R; Paskins, Z; Peat, G; Roberts, P; Roddy, E; Stevenson, K, 2022)
"Diclofenac was highly effective in both tests on day 3, while on day 20 it induced a less pronounced decrease in the Knee-Bend score and was ineffective in the CatWalk test."5.38Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis. ( Adães, S; Castro-Lopes, JM; Ferreira-Gomes, J; Mendonça, M, 2012)
"The aim of this trial was to assess the relative efficacy of a sage/echinacea spray and a chlorhexidine/lidocaine spray in the treatment of acute sore throats."5.14Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. ( Berger, D; Klein, P; Schapowal, A; Suter, A, 2009)
" Joint pain relief from lidocaine administration could be reliably tracked over its brief acting time course."3.79Intra-articular anaesthesia mitigates established pain in experimental osteoarthritis: a preliminary study of gait impulse redistribution as a biomarker of analgesia pharmacodynamics. ( Bertram, JE; Gutmann, A; Hurtig, M; Matyas, JR; Randev, J, 2013)
"The site of referred pain may depend on which SIJ section is affected."2.80Referred pain location depends on the affected section of the sacroiliac joint. ( Aizawa, T; Kurosawa, D; Murakami, E, 2015)
"The chronic cervical facet joint pain was diagnosed with cervical facet joint nerve blocks at a prevalence of 49."1.56Assessment of Prevalence of Cervical Facet Joint Pain with Diagnostic Cervical Medial Branch Blocks: Analysis Based on Chronic Pain Model. ( Cash, KA; Hirsch, JA; Kaye, AD; Kosanovic, R; Manchikanti, L; Pampati, V; Soin, A, 2020)
"Osteoarthritis is the most common form of arthritis and includes manifestations of both nociceptive and neuropathic mechanisms."1.40Osteoarthritis pain has a significant neuropathic component: an exploratory in vivo patient model. ( Ashford, RL; Dimitroulas, T; Duarte, RV; Kitas, GD; Raphael, JH; Southall, JL; Sparkes, E, 2014)
"Diclofenac was highly effective in both tests on day 3, while on day 20 it induced a less pronounced decrease in the Knee-Bend score and was ineffective in the CatWalk test."1.38Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis. ( Adães, S; Castro-Lopes, JM; Ferreira-Gomes, J; Mendonça, M, 2012)
"Measuring primary hyperalgesia from deep somatic tissue (ie, muscle and joint) is difficult in laboratory animals but clinically important."1.33Characterization of a method for measuring primary hyperalgesia of deep somatic tissue. ( Radhakrishnan, R; Skyba, DA; Sluka, KA, 2005)
"Hyperalgesia was induced in rats by inflaming one knee joint with 3% kaolin-carrageenan and assessed by measuring paw withdrawal latency to heat before and 4 hours after injection."1.33Deep tissue afferents, but not cutaneous afferents, mediate transcutaneous electrical nerve stimulation-Induced antihyperalgesia. ( Radhakrishnan, R; Sluka, KA, 2005)
"In the IR group, joint pain was well relieved from the early stage of treatment."1.32Comparative study of intra-articular irrigation and corticosteroid injection versus closed reduction with intermaxillary fixation for the management of mandibular condyle fractures. ( Hamada, Y; Horie, A; Iino, M; Kamei, K; Kobayakawa, M; Kobayashi, K; Kondoh, T; Seto, K, 2004)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.13)18.2507
2000's12 (37.50)29.6817
2010's16 (50.00)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Paskins, Z1
Bromley, K1
Lewis, M1
Hughes, G1
Hughes, E1
Hennings, S1
Cherrington, A1
Hall, A1
Holden, MA1
Stevenson, K1
Menon, A1
Roberts, P1
Peat, G1
Jinks, C1
Kigozi, J1
Oppong, R1
Foster, NE1
Mallen, CD1
Roddy, E1
Schneider, BJ1
Ehsanian, R1
Rosati, R1
Huynh, L1
Levin, J1
Kennedy, DJ1
Manchikanti, L1
Kosanovic, R1
Cash, KA1
Pampati, V1
Soin, A1
Kaye, AD1
Hirsch, JA1
Allen, J2
Imbert, I2
Havelin, J2
Henderson, T1
Stevenson, G1
Liaw, L1
King, T2
Lee, DH1
Lee, MY1
Kwack, KS1
Yoon, SH1
Crijns, TJ1
Teunis, T1
Chen, NC1
Ring, D1
Lee, DW1
Huston, C1
Leliveld, MS1
Kamphuis, SJM1
Verhofstad, MHJ1
Matyas, JR1
Gutmann, A1
Randev, J1
Hurtig, M1
Bertram, JE1
Duarte, RV1
Raphael, JH1
Dimitroulas, T1
Sparkes, E1
Southall, JL1
Ashford, RL1
Kitas, GD1
Kurosawa, D2
Murakami, E3
Aizawa, T2
Cormier, J1
Porreca, F1
Chen, B1
Rispoli, L1
Stitik, T1
Leong, M1
Ozawa, H1
Koga, H1
Isu, T1
Chiba, Y1
Abe, E1
Unoki, E1
Musha, Y1
Ito, K1
Katoh, S1
Yamaguchi, T1
Borick, JM1
Kurzweil, PR1
Kivitz, A1
Fairfax, M1
Sheldon, EA1
Xiang, Q1
Jones, BA1
Gammaitoni, AR1
Gould, EM1
Loughnan, TE1
Taverner, MG1
Webb, A1
Schapowal, A1
Berger, D1
Klein, P1
Suter, A1
Cooper, AJ1
Clifford, PD1
Parikh, VK1
Steinmetz, ND1
Mizel, MS1
Geber, C1
Cheok, CY1
Mohamad, JA1
Ahmad, TS1
Ferreira-Gomes, J1
Adães, S1
Mendonça, M1
Castro-Lopes, JM1
Dumais, R1
Benoit, C1
Dumais, A1
Babin, L1
Bordage, R1
de Arcos, C1
Allard, J1
Bélanger, M1
Mosimann, PJ1
Richarme, D1
Becce, F1
Knoepfli, AS1
Mino, V1
Meuli, R1
Theumann, N1
Kondoh, T1
Hamada, Y1
Kamei, K1
Kobayakawa, M1
Horie, A1
Iino, M1
Kobayashi, K1
Seto, K1
Skyba, DA1
Radhakrishnan, R2
Sluka, KA2
Oliveira, MC1
Parada, CA1
Veiga, MC1
Rodrigues, LR1
Barros, SP1
Tambeli, CH1
Tanaka, Y1
Ishizuka, M1
Kokubun, S1
Laban, MM1
Broadhurst, NA1
Bond, MJ1
Elgafy, H1
Semaan, HB1
Ebraheim, NA1
Coombs, RJ1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Minimally Invasive Knee Osteoarthritis Pain Control Via Adductor Canal Block Versus Intra-articular Steroid and Lignocaine Injection : a Single-blinded Controlled Trial[NCT04264481]64 participants (Actual)Interventional2019-07-12Completed
Multicentric Randomized Double Blind Double Dummy Placebo Controlled Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray in Comparison to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats[NCT00707902]Phase 3154 participants (Actual)Interventional2006-02-28Completed
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection: A Randomised Clinical Trial of Efficacy[NCT01706172]Phase 2/Phase 342 participants (Actual)Interventional2013-01-31Completed
Somatosensory Electrical Stimulation to Improve Motor Control in Patients Suffering From Knee Osteoarthritis[NCT02854176]Phase 220 participants (Anticipated)Interventional2016-09-30Not yet recruiting
High-frequency Sinusoidal Neurostimulation (BioWave) Versus Transcutaneous Electrical Nerve Stimulation (TENS) for the Treatment of Chronic Low Back Pain[NCT05511181]120 participants (Actual)Interventional2022-08-15Completed
IRB-HSR # 14073 Investigation of Pelvic Girdle Dysfunction in the Low Back Pain Population[NCT02950129]Phase 255 participants (Actual)Interventional2009-02-28Completed
A Cross Sectional Study to Determine the Association Between Diastasis Recti Abdominis and Sacroiliac Joint and Pelvic Floor Dysfunction Outcomes Among Postpartum Women Who Underwent C-section in UAE[NCT04519840]32 participants (Actual)Observational [Patient Registry]2020-12-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

11 trials available for lidocaine and Joint Pain

ArticleYear
Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial.
    BMJ (Clinical research ed.), 2022, 04-06, Volume: 377

    Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Arthralgia; Female; Humans; Injections, Intra-Ar

2022
Psychologic Factors Do Not Affect Placebo Responses After Upper Extremity Injections: A Randomized Trial.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Anesthetics, Local; Arthralgia; Attitude of Health Personnel; Carpometacarpal Joints; Clinica

2018
An infrapatellar nerve block reduces knee pain in patients with chronic anterior knee pain after tibial nailing: a randomized, placebo-controlled trial in 34 patients.
    Acta orthopaedica, 2019, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Local; Arthralgia; Bone Nails; Female; Fracture Fixation, Internal;

2019
Referred pain location depends on the affected section of the sacroiliac joint.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2015, Volume: 24, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Arthralgia; Buttocks; Female; Groin; Humans; Inj

2015
Comparison of the effectiveness and tolerability of lidocaine patch 5% versus celecoxib for osteoarthritis-related knee pain: post hoc analysis of a 12 week, prospective, randomized, active-controlled, open-label, parallel-group trial in adults.
    Clinical therapeutics, 2008, Volume: 30, Issue:12

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Anesthetics, Local; Arthralgia; Celeco

2008
Randomized, double blinded comparative trial of intradermal injections of lignocaine versus N-saline around the knee to relieve pain in patients awaiting total knee replacement.
    The Clinical journal of pain, 2009, Volume: 25, Issue:4

    Topics: Anesthetics, Local; Arthralgia; Arthroplasty, Replacement, Knee; Double-Blind Method; Female; Humans

2009
Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial.
    European journal of medical research, 2009, Sep-01, Volume: 14, Issue:9

    Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Anti-Infective Agents, Local;

2009
Pain relief for reduction of acute anterior shoulder dislocations: a prospective randomized study comparing intravenous sedation with intra-articular lidocaine.
    Journal of orthopaedic trauma, 2011, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Local; Arthralgia; Female; Humans; Injections, Intra-Articular; Inje

2011
Effect of regenerative injection therapy on function and pain in patients with knee osteoarthritis: a randomized crossover study.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:8

    Topics: Aged; Anesthetics, Local; Arthralgia; Cross-Over Studies; Exercise Therapy; Female; Follow-Up Studie

2012
Usefulness of intra-articular bupivacain and lidocain adjunction in MR or CT arthrography: a prospective study in 148 patients.
    European journal of radiology, 2012, Volume: 81, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Arthralgia; Arthrography; Bupivacaine; Drug Ther

2012
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
    Journal of spinal disorders, 1998, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method;

1998
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
    Journal of spinal disorders, 1998, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method;

1998
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
    Journal of spinal disorders, 1998, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method;

1998
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
    Journal of spinal disorders, 1998, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method;

1998

Other Studies

21 other studies available for lidocaine and Joint Pain

ArticleYear
Validity of Physical Exam Maneuvers in the Diagnosis of Sacroiliac Joint Pathology.
    Pain medicine (Malden, Mass.), 2020, 02-01, Volume: 21, Issue:2

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Arthralgia; Female; Humans; Injections, Intra-Ar

2020
Assessment of Prevalence of Cervical Facet Joint Pain with Diagnostic Cervical Medial Branch Blocks: Analysis Based on Chronic Pain Model.
    Pain physician, 2020, Volume: 23, Issue:6

    Topics: Adult; Anesthetics, Local; Arthralgia; Bupivacaine; Chronic Pain; Female; Humans; Lidocaine; Male; M

2020
Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.
    Arthritis & rheumatology (Hoboken, N.J.), 2017, Volume: 69, Issue:7

    Topics: Anesthetics, Local; Animals; Arthralgia; Arthritis, Experimental; Behavior, Animal; Disease Models,

2017
Effect of adductor canal block on medial compartment knee pain in patients with knee osteoarthritis: Retrospective comparative study.
    Medicine, 2017, Volume: 96, Issue:12

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Arthralgia; Case-Control Studies; Female; Follow

2017
Fluoroscopically-Guided Cervical Zygapophyseal Therapeutic Joint Injections May Reduce the Need for Radiofrequency.
    Pain physician, 2018, Volume: 21, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Arthralgia; Betamethasone; Bupivacaine; Female; Humans; Injections,

2018
Intra-articular anaesthesia mitigates established pain in experimental osteoarthritis: a preliminary study of gait impulse redistribution as a biomarker of analgesia pharmacodynamics.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:9

    Topics: Anesthetics, Local; Animals; Anterior Cruciate Ligament Injuries; Anti-Inflammatory Agents, Non-Ster

2013
Osteoarthritis pain has a significant neuropathic component: an exploratory in vivo patient model.
    Rheumatology international, 2014, Volume: 34, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Arthralgia; Female; Humans; Infusions, Intravenous; Lidocaine; Male

2014
Central Sensitization and Neuropathic Features of Ongoing Pain in a Rat Model of Advanced Osteoarthritis.
    The journal of pain, 2016, Volume: 17, Issue:3

    Topics: Analgesics; Animals; Arthralgia; Central Nervous System Sensitization; Disease Models, Animal; Dose-

2016
Successful Treatment of Gluteal Pain from Obturator Internus Tendinitis and Bursitis with Ultrasound-Guided Injection.
    American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:10

    Topics: Anesthetics, Local; Anti-Inflammatory Agents; Arthralgia; Bursitis; Female; Hip Joint; Humans; Injec

2017
A Diagnostic Scoring System for Sacroiliac Joint Pain Originating from the Posterior Ligament.
    Pain medicine (Malden, Mass.), 2017, 02-01, Volume: 18, Issue:2

    Topics: Adult; Aged; Anesthetics, Local; Arthralgia; Case-Control Studies; Female; Humans; Injections, Intra

2017
Magnetic resonance imaging appearance of the shoulder after subacromial injection with corticosteroids can mimic a rotator cuff tear.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2008, Volume: 24, Issue:7

    Topics: Adrenal Cortex Hormones; Arthralgia; Betamethasone; Diagnosis, Differential; Diagnostic Errors; Fema

2008
Instability of the first metatarsal-cuneiform joint: diagnosis and discussion of an independent pain generator in the foot.
    Foot & ankle international, 2009, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Arthralgia; Arthrodesis; Bupivacaine

2009
Spotting the pain in fibromyalgia syndrome--widespread effects of local pain therapy.
    European journal of pain (London, England), 2011, Volume: 15, Issue:1

    Topics: Anesthetics, Local; Arthralgia; Facial Pain; Fibromyalgia; Humans; Lidocaine; Pain; Syndrome; Treatm

2011
Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:4

    Topics: Administration, Oral; Analgesics; Animals; Arthralgia; Diclofenac; Disease Models, Animal; Injection

2012
Comparative study of intra-articular irrigation and corticosteroid injection versus closed reduction with intermaxillary fixation for the management of mandibular condyle fractures.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2004, Volume: 98, Issue:6

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Arthralgia; Dental Occlusion; Dexamethasone; Fe

2004
Characterization of a method for measuring primary hyperalgesia of deep somatic tissue.
    The journal of pain, 2005, Volume: 6, Issue:1

    Topics: Animals; Arthralgia; Carrageenan; Disease Models, Animal; Functional Laterality; Hyperalgesia; Infla

2005
Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain.
    European journal of pain (London, England), 2005, Volume: 9, Issue:1

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arthralgia; Arthritis; Carrageenan; Disea

2005
Deep tissue afferents, but not cutaneous afferents, mediate transcutaneous electrical nerve stimulation-Induced antihyperalgesia.
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Administration, Topical; Afferent Pathways; Anesthetics, Local; Animals; Arthralgia; Carrageenan; Hy

2005
Deep tissue afferents, but not cutaneous afferents, mediate transcutaneous electrical nerve stimulation-Induced antihyperalgesia.
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Administration, Topical; Afferent Pathways; Anesthetics, Local; Animals; Arthralgia; Carrageenan; Hy

2005
Deep tissue afferents, but not cutaneous afferents, mediate transcutaneous electrical nerve stimulation-Induced antihyperalgesia.
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Administration, Topical; Afferent Pathways; Anesthetics, Local; Animals; Arthralgia; Carrageenan; Hy

2005
Deep tissue afferents, but not cutaneous afferents, mediate transcutaneous electrical nerve stimulation-Induced antihyperalgesia.
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Administration, Topical; Afferent Pathways; Anesthetics, Local; Animals; Arthralgia; Carrageenan; Hy

2005
Effect of periarticular and intraarticular lidocaine injections for sacroiliac joint pain: prospective comparative study.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2007, Volume: 12, Issue:3

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Arthralgia; Female;

2007
Re: sacroiliac joint pain: anatomy, biomechanics, diagnosis, and treatment.
    American journal of physical medicine & rehabilitation, 2007, Volume: 86, Issue:12

    Topics: Anesthetics, Local; Arthralgia; Biomechanical Phenomena; Humans; Injections, Intra-Articular; Lidoca

2007
Computed tomography findings in patients with sacroiliac pain.
    Clinical orthopaedics and related research, 2001, Issue:382

    Topics: Adolescent; Adult; Anesthetics, Local; Ankylosis; Anti-Inflammatory Agents; Arthralgia; Betamethason

2001