lidocaine has been researched along with Irritable Bowel Syndrome in 6 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Previous studies have reported the potential anti-inflammatory properties of lidocaine and its ability to alleviate visceral hypersensitivity in individuals with irritable bowel syndrome (IBS)." | 8.31 | Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2. ( Chen, J; Feng, Z; Guo, Y; Hu, R; Liu, J; Liu, L; Qiao, M; Sun, Y; Wang, Y; Yao, X, 2023) |
| "This study shows that lidocaine, a peripheral analgesic, significantly altered DMN connectivity and affected its relationship with pain-related networks." | 7.79 | Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment. ( Craggs, JG; Letzen, JE; Perlstein, WM; Price, DD; Robinson, ME, 2013) |
| " Previous studies have reported the potential anti-inflammatory properties of lidocaine and its ability to alleviate visceral hypersensitivity in individuals with irritable bowel syndrome (IBS)." | 4.31 | Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2. ( Chen, J; Feng, Z; Guo, Y; Hu, R; Liu, J; Liu, L; Qiao, M; Sun, Y; Wang, Y; Yao, X, 2023) |
| "This study shows that lidocaine, a peripheral analgesic, significantly altered DMN connectivity and affected its relationship with pain-related networks." | 3.79 | Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment. ( Craggs, JG; Letzen, JE; Perlstein, WM; Price, DD; Robinson, ME, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Qiao, M | 1 |
| Yao, X | 1 |
| Feng, Z | 1 |
| Hu, R | 1 |
| Chen, J | 1 |
| Liu, L | 1 |
| Liu, J | 1 |
| Sun, Y | 1 |
| Guo, Y | 1 |
| Letzen, JE | 1 |
| Craggs, JG | 1 |
| Perlstein, WM | 1 |
| Price, DD | 3 |
| Robinson, ME | 2 |
| Ducrotté, P | 1 |
| Vase, L | 1 |
| Verne, NG | 1 |
| Verne, GN | 1 |
| Sen, A | 1 |
| Mayer, EA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain Imaging and Pain: Analysis of Placebo Analgesia[NCT01409538] | Phase 1 | 140 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lidocaine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Commentary on peripheral and central contributions to hyperalgesia in irritable bowel syndrome.
Topics: Administration, Rectal; Anesthetics, Local; Central Nervous System; Chronic Disease; Humans; Hyperal | 2006 |
2 trials available for lidocaine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Increased placebo analgesia over time in irritable bowel syndrome (IBS) patients is associated with desire and expectation but not endogenous opioid mechanisms.
Topics: Adult; Analgesia; Anesthetics, Local; Anxiety; Attitude to Health; Female; Humans; Irritable Bowel S | 2005 |
Intrarectal lidocaine is an effective treatment for abdominal pain associated with diarrhea-predominant irritable bowel syndrome.
Topics: Abdominal Pain; Administration, Rectal; Adult; Anesthetics, Local; Colon; Cross-Over Studies; Diarrh | 2005 |
3 other studies available for lidocaine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Topics: Animals; Caco-2 Cells; Corticotropin-Releasing Hormone; Humans; Irritable Bowel Syndrome; Lidocaine; | 2023 |
Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment.
Topics: Administration, Rectal; Adult; Anesthetics, Local; Data Interpretation, Statistical; Female; Functio | 2013 |
[Irritable bowel syndrome: dietary and pharmacological therapeutic options].
Topics: Abdominal Pain; Analgesics; Anesthetics, Local; Anti-Bacterial Agents; Antidepressive Agents; Centra | 2009 |