Page last updated: 2024-10-28

lidocaine and Intracranial Aneurysm

lidocaine has been researched along with Intracranial Aneurysm in 20 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (

Research Excerpts

ExcerptRelevanceReference
"This study aimed to explore the effect and mechanism of lidocaine pretreatment combined with dexmedetomidine on oxidative stress in patients with intracranial aneurysm clipping."9.41Effect and Mechanism of Lidocaine Pretreatment Combined with Dexmedetomidine on Oxidative Stress in Patients with Intracranial Aneurysm Clipping. ( Liu, Y; Zhang, H; Zhang, J; Zhao, L; Zhao, Z, 2021)
"This study aimed to explore the effect and mechanism of lidocaine pretreatment combined with dexmedetomidine on oxidative stress in patients with intracranial aneurysm clipping."5.41Effect and Mechanism of Lidocaine Pretreatment Combined with Dexmedetomidine on Oxidative Stress in Patients with Intracranial Aneurysm Clipping. ( Liu, Y; Zhang, H; Zhang, J; Zhao, L; Zhao, Z, 2021)
"Alfentanil was very effective in obtunding this response with stable cardiovascular parameters; fentanyl produced a more variable response; and intravenous lignocaine was less satisfactory."2.66Obtunding the sympathetic response to intubation. Experience at 2 minutes after administration of the test agent in patients with cerebral aneurysms. ( Murray, WB; Oosthuizen, JH; Payne, KA, 1988)
"Headaches are a common symptom during pregnancy."1.48Management of anesthesia for cesarean delivery in a patient with an unruptured intracranial aneurysm. ( Parikh, N, 2018)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199011 (55.00)18.7374
1990's0 (0.00)18.2507
2000's3 (15.00)29.6817
2010's4 (20.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Matas, M2
Sotošek, V2
Kozmar, A2
Likić, R2
Mrak, G1
Nagy, B1
Sekulić, A2
Zhang, J1
Zhang, H1
Zhao, L1
Zhao, Z1
Liu, Y1
Parikh, N2
Tomar, GS1
Goyal, K1
Chandran, R1
Luthra, A1
Chauhan, V1
Kumar, N1
Li, QY1
Xu, WL1
Zhang, Y1
Lu, PS1
Yuan, ZC1
Zhan, LP1
Wang, P1
Lu, XY1
Cheng, B1
Mathioudakis, D1
Lüthen, C1
Hoff, RG1
VAN Dijk, GW1
Mettes, S1
Verweij, BH1
Algra, A1
Rinkel, GJ1
Kalkman, CJ1
Ozköse, Z1
Yardim, S1
Yurtlu, S1
Doğulu, F1
Kaymaz, M1
Paşaoğlu, A1
Kim, H1
Mizukami, M1
Kawase, T1
Tazawa, T1
Araki, G1
Shizuka, M1
Yunoki, K1
Nagata, K1
Sundt, TM3
Lundberg, GD1
Garriott, JC1
Reynolds, PC1
Cravey, RH1
Shaw, RF1
Giannotta, SL1
Kindt, GW2
Haar, FL1
Grossman, MA1
Payne, KA1
Murray, WB1
Oosthuizen, JH1
Bachofen, M1
Robertson, JT1
Hudson, JS1
Gosh, HH1
Gabrielsen, TO1
Onofrio, BM1
Merideth, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Regional Anesthesia With Lidocaine on Perioperative Levels of Interleukin-1β, Interleukin-6 and Tumor Necrosis Factor-α in Blood and Cerebrospinal Fluid in Cerebral Aneurysm Patients[NCT03823482]40 participants (Anticipated)Interventional2019-03-01Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lidocaine and Intracranial Aneurysm

ArticleYear
Cerebral arterial spasm: current concepts.
    Clinical neurosurgery, 1974, Volume: 21

    Topics: Anesthesia, General; Animals; Blood Coagulation; Blood Platelets; Brain; Catecholamines; Cerebral Ar

1974

Trials

6 trials available for lidocaine and Intracranial Aneurysm

ArticleYear
Effect of adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia vs general anesthesia only on plasma and cerebrospinal fluid pro-inflammatory cytokine concentrations in patients with cerebral aneurysm: a randomized controlled trial.
    Croatian medical journal, 2021, Aug-31, Volume: 62, Issue:4

    Topics: Anesthesia, General; Anesthesia, Local; Anesthetics, Local; Cytokines; Humans; Intracranial Aneurysm

2021
Effect and Mechanism of Lidocaine Pretreatment Combined with Dexmedetomidine on Oxidative Stress in Patients with Intracranial Aneurysm Clipping.
    Journal of healthcare engineering, 2021, Volume: 2021

    Topics: Animals; Dexmedetomidine; Hemodynamics; Humans; Intracranial Aneurysm; Lidocaine; Oxidative Stress;

2021
Effect of local anesthesia with lidocaine on perioperative proinflammatory cytokine levels in plasma and cerebrospinal fluid in cerebral aneurysm patients: Study protocol for a randomized clinical trial.
    Medicine, 2019, Volume: 98, Issue:42

    Topics: Adolescent; Adult; Aged; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Local; Anesthetics

2019
The effects of intravenous fentanyl and lidocaine infiltration on the hemodynamic response to skull pin placement.
    Neurosurgical review, 2001, Volume: 24, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Blood Pressure; Bone Nails; Brain Neoplasms

2001
Obtunding the sympathetic response to intubation. Experience at 2 minutes after administration of the test agent in patients with cerebral aneurysms.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1988, May-21, Volume: 73, Issue:10

    Topics: Adult; Alfentanil; Anesthesia, Endotracheal; Anesthetics; Blood Pressure; Fentanyl; Humans; Intracra

1988
[Suppression of blood pressure increases during intubation: lidocaine or fentanyl?].
    Der Anaesthesist, 1988, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Pressure; Brain Neoplasms; Child; Female; Fentanyl; Humans; Hypertens

1988

Other Studies

13 other studies available for lidocaine and Intracranial Aneurysm

ArticleYear
Management of anesthesia for cesarean delivery in a patient with an unruptured intracranial aneurysm.
    International journal of obstetric anesthesia, 2018, Volume: 36

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Carotid Arter

2018
Aneurysmal hemorrhage in a pregnant patient with coarctation of aorta: An anesthetic challenge.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Adult; Anesthesia, General; Aortic Coarctation; Craniotomy; Female; Fentanyl; Humans; Intracranial A

2017
Intravascular infusion of lidocaine: a novel way to relieve sudden internal carotid artery occlusion in embolization of intracranial aneurysms.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:2

    Topics: Aged; Carotid Artery, Internal; Carotid Stenosis; Embolization, Therapeutic; Female; Humans; Infusio

2012
"Wrapped it up!" Ultra-fast-tracking the unsecured intracranial aneurysm.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:3

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Local; Antiemetics

2007
Hypotension in anaesthetized patients during aneurysm clipping: not as bad as expected?
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Atracurium; Cohort Studies; Etomidate; Fem

2008
[Treatment of cerebral vasospasm by topical application of lidocaine (author's transl)].
    Neurologia medico-chirurgica, 1979, Volume: 19, Issue:8

    Topics: Administration, Topical; Adult; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; L

1979
Cerebral vasospasm following subarachnoid hemorrhage: evolution, management, and relationship to timing of surgery.
    Clinical neurosurgery, 1977, Volume: 24

    Topics: Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Isoproterenol; Lidocaine; Postoperative C

1977
Cocaine-related death.
    Journal of forensic sciences, 1977, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Brain Edema; Cocaine; Ethanol; Female; Forensic Medi

1977
Management of ischemic complications after subarachnoid hemorrhage.
    Journal of neurosurgery, 1975, Volume: 43, Issue:4

    Topics: Adult; Aged; Brain; Female; Humans; Intracranial Aneurysm; Ischemia; Ischemic Attack, Transient; Iso

1975
Topical lidocaine in treatment of cerebral vasospasm.
    Surgical neurology, 1975, Volume: 4, Issue:1

    Topics: Administration, Topical; Animals; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Lidocai

1975
Cardiac arrhythmias in acute central nervous system disease. Successful management with stellate ganglion block.
    Archives of internal medicine, 1976, Volume: 136, Issue:2

    Topics: Basilar Artery; Cerebral Hemorrhage; Electrocardiography; Female; Humans; Intracranial Aneurysm; Lid

1976
Relief of arterial spasm associated with cerebral aneurysms.
    European neurology, 1972, Volume: 8, Issue:1

    Topics: Animals; Cerebral Angiography; Cerebral Arterial Diseases; Cerebrovascular Circulation; Haplorhini;

1972
Treatment of cerebral vasospasm from subarachnoid hemorrhage with isoproterenol and lidocaine hydrochloride.
    Journal of neurosurgery, 1973, Volume: 38, Issue:5

    Topics: Adult; Aged; Arrhythmias, Cardiac; Evaluation Studies as Topic; Female; Humans; Intracranial Aneurys

1973