Page last updated: 2024-10-28

lidocaine and Injuries, Knee

lidocaine has been researched along with Injuries, Knee in 9 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The authors conducted an unfunded randomized controlled trial approved by the Brooke Army Medical Center (BAMC) Institutional Review Board (IRB) to determine the possible efficacy of intra-articular morphine for pain in acute knee injuries."5.19Intra-articular Morphine versus Lidocaine for Acute Knee Pain. ( Cuenca, PJ; Graham, RF; Hughes, JR; Johnson, AE; Mosely, T, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ravnihar, K1
Barlič, A1
Drobnič, M1
Graham, RF1
Hughes, JR1
Johnson, AE1
Cuenca, PJ1
Mosely, T1
Ageberg, E1
Björkman, A1
Rosén, B1
Roos, EM1
LEACH, RE1
ZOHN, DA1
Friemert, B1
Bumann-Melnyk, M1
Faist, M1
Schwarz, W1
Gerngross, H1
Claes, L1
Palmieri-Smith, RM1
Kreinbrink, J1
Ashton-Miller, JA1
Wojtys, EM1
Sekhon, JS1
Anderson, K1
Fullerton, BD1
Cappellino, A1
Jokl, P1
Ruwe, PA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effect of Intra-articular Administration of 2% Ropivacaine vs. 7.5% Ropivacaine as an Analgesic in the Immediate Postoperative Period of Knee Arthroscopy in Acute Injuries at the ABC Medical Center[NCT05807945]Phase 468 participants (Actual)Interventional2020-04-01Completed
Quadriceps Activation Comparative Analysis Based on Positioning of the Ankle During Supine Straight Leg Raise and Quad Set[NCT05568784]100 participants (Anticipated)Observational2021-04-11Recruiting
Rotator Cuff Tendinopathy: A Randomized and Blinded Comparison of Superficial and Deep Injection Methods[NCT01402011]77 participants (Actual)Interventional2010-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Maximum Pain Score at 9 Months

Participants were asked about pain at rest, at work, doing sports. The maximum pain reported on a scale ranging from 0 (no pain at all) to 10 (extreme pain) was recorded for each participant. Maximum of pain scores rest, work, sport recorded. Calculated as pain at baseline - pain at 9 months. (NCT01402011)
Timeframe: baseline and 9 months

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons2.9
.1% Lidocaine in Ligaments and Tendons1.8
.1% Lidocaine Subcutaneous1.3

Change From Baseline of Visual Analog Pain Scale at 3 Months

Subject marks his pain level at rest, at work, doing sports on a 10 cm scale. Maximum of pain scores rest, work, sport recorded. Calculated as pain at baseline - pain at 3 months. VAS scale is from 0 = no pain to 10 = maximum pain (NCT01402011)
Timeframe: baseline and three months

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons3.0
.1% Lidocaine in Ligaments and Tendons2.7
.1% Lidocaine Subcutaneous2.7

Nine Month Satisfaction Questionnaire

Phone call asking how satisfied were they with their treatment 10 = extremely satisfied, 0 = extremely dissatisfied ) (NCT01402011)
Timeframe: Nine months after first injection treatment appointment

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons6.7
.1% Lidocaine in Ligaments and Tendons4.7
.1% Lidocaine Subcutaneous3.9

Visual Analog Pain Scale 0= no Pain 10 = Maximum Pain

Subject marks his pain level at rest, at work, doing sports on a 10 cm scale. The maximum pain level among the 3 different activities was recorded. (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit

Interventionunits on a scale (Mean)
25% Dextrose in Shoulder Entheses7.3
.1% Lidocaine in Shoulder Entheses6.9
.1% Lidocaine Subcu. Above Shouldr Enth.6.9

Disabilities of the Arm Shoulder and Hand Questionnaire

http://www.dash.iwh.on.ca/assets/images/pdfs/DASH_quest06.pdf 30 questions assessing ability to use shoulder in everyday activities, each question scored 1 to 5, where one is normal, no problem and five is unable to perform. No data was collected at 9 months. The score ranges from 30 to 150. Higher scores represent worse outcomes. (NCT01402011)
Timeframe: 20 minutes before the first injection and at 3 months

,,
Interventionunits on a scale (Mean)
Baseline3 months
.1% Lidocaine in Ligaments and Tendons71.354.7
.1% Lidocaine Subcutaneous69.661
25% Dextrose in Ligaments and Tendons72.461.3

Physical Examination of the Shoulder Scale

From Steven W. Brose, DO, Michael L. Boninger, MD, Bradley Fullerton, MD, Thane McCann, MD, From: Jennifer L. Collinger, BSE, Bradley G. Impink, BSE, Trevor A. Dyson-Hudson, MD Shoulder ultrasound abnormalities, physical examination findings, and pain in manual wheelchair users with spinal cord injury. Arch Phys Med Rehabil 2008 Nov; 89:2086-93, appendix 1 12 parameters of shoulder examination: Biceps tendon/bicipital groove tenderness, Supraspinatus tendon/greater tuberosity tenderness Acromioclavicular joint tenderness Resisted external rotation. Resisted internal rotation. Supraspinatus test. Painful Arc Test. Neer impingement sign. Hawkins-Kennedy impingement sign. O'Brien Active Compression Test for AC Joint Pathology O'Brien Active Compression Test for Labral Pathology impingement sign. each test scored 0 = no pain, 1 = tenderness, 2 = pain. All 12 scores added. Range 0-24. Higher scores = more pathology (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit and at 3 months

,,
Interventionunits on a scale (Mean)
Baseline3 months
.1% Lidocaine in Ligaments and Tendons13.110.7
.1% Lidocaine Subcutaneous1312.9
25% Dextrose in Ligaments and Tendons13.211.4

Rotator Cuff Ultrasound, Ultrasound Shoulder Pathology Rating Scale

"From Brose et al. shoulder ultrasound abnormalities, physical examination findings, and pain in manual wheelchair users with spinal cord injury Arch Phys Med Rehabil 2008 Nov, 89: 2086-93 appendix 2. rates biceps tendinopathy (0-6), supraspinatus tendinopathy (0-5), greater tuberosity the cortical surface (0-3), dynamics supraspinatus impingement (0-3), dynamic subscapularis/ biceps/ coracoid impingement (0-3). The total score ranged from 0 to 20 with higher scores indicating a worse outcome. The change was calculated by taking the final score - the baseline score." (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit and at on average 9.4 months

,,
Interventionunits on a scale (Mean)
Baselinechange at 9.4 +/- 2.2 months
.1% Lidocaine in Ligaments and Tendons4.3-0.6
.1% Lidocaine Subcutaneous4.3-0.6
25% Dextrose in Ligaments and Tendons4.0-0.3

Trials

2 trials available for lidocaine and Injuries, Knee

ArticleYear
Intra-articular Morphine versus Lidocaine for Acute Knee Pain.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2014,Summer, Volume: 14, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Drug Therapy, Combinati

2014
Principles of brain plasticity in improving sensorimotor function of the knee and leg in patients with anterior cruciate ligament injury: a double-blind randomized exploratory trial.
    BMC musculoskeletal disorders, 2012, May-10, Volume: 13

    Topics: Administration, Cutaneous; Anesthetics, Local; Anterior Cruciate Ligament Injuries; Brain; Double-Bl

2012

Other Studies

7 other studies available for lidocaine and Injuries, Knee

ArticleYear
Effect of intra-articular local anesthesia on articular cartilage in the knee.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2014, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Arthroscopy; Biopsy; Cartilage, Articular;

2014
A SIMPLE METHOD FOR REDUCING A DISLOCATED PATELLA.
    The American journal of orthopedics, 1963, Volume: 5

    Topics: Humans; Injections, Intramuscular; Joint Dislocations; Knee Injuries; Lidocaine; Manipulation, Ortho

1963
Differentiation of hamstring short latency versus medium latency responses after tibia translation.
    Experimental brain research, 2005, Volume: 160, Issue:1

    Topics: Adult; Algorithms; Anterior Cruciate Ligament; Female; Humans; Knee Injuries; Knee Joint; Lidocaine;

2005
Quadriceps inhibition induced by an experimental knee joint effusion affects knee joint mechanics during a single-legged drop landing.
    The American journal of sports medicine, 2007, Volume: 35, Issue:8

    Topics: Adolescent; Adult; Biomechanical Phenomena; Cross-Over Studies; Female; Humans; Knee Injuries; Knee

2007
Rupture of the distal semitendinosus tendon: a report of two cases in professional athletes.
    The journal of knee surgery, 2007, Volume: 20, Issue:2

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Baseball; Bupivacaine; Cryothera

2007
High-resolution ultrasound and magnetic resonance imaging to document tissue repair after prolotherapy: a report of 3 cases.
    Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Anesthetics, Local; Ankle Injuries; Athletic Injuries; Chronic Disease; Female; G

2008
Regional anesthesia in knee arthroscopy: a new technique involving femoral and sciatic nerve blocks in knee arthroscopy.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 1996, Volume: 12, Issue:1

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Anterior Cruciate Ligament; Anterior Cruciate Lig

1996