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lidocaine and Inflammation, Endodontic

lidocaine has been researched along with Inflammation, Endodontic in 140 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this double-blind clinical trial was to compare the effect of preoperative tramadol 50 mg, tramadol 100 mg, ibuprofen 600 mg, ibuprofen 600 mg/acetaminophen 1000 mg or placebo 60 min before the administration of inferior alveolar nerve blocks (IANB) of mandibular teeth in patients experiencing symptomatic irreversible pulpitis (SIP)."9.69Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. ( Badr, AE; Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023)
"Premedication with meloxicam, ketorolac, dexamethasone, and ibuprofen increased the efficacy of IANB in mandibular molars with symptomatic irreversible pulpitis."9.69Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial. ( Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023)
"Successful anesthesia (defined as no or mild pain during any of steps and no need for additional injection) is obtained in 12% of patients in the lidocaine group, while DEX-lidocaine group increased the success rate of IANB to 72% (p-value = 0."9.51Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial. ( Moshari, A; Moshari, M; Vahedi, Z, 2022)
"The aim of this study was to assess inferior alveolar nerve block (IANB) success of 2% mepivacaine (Scandonest 2%, Septodont, France) and 4% articaine (Septanest 4%, Septodont) in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation."9.51Inferior alveolar nerve block success of 2% mepivacaine versus 4% articaine in patients with symptomatic irreversible pulpitis in mandibular molars: A randomized double-blind single-centre clinical trial. ( Amin, SAW; Bedier, MM; El Boghdadi, RM; Ezzat, K; Fouda, MY; Gawdat, SI; Habib, MFOM; Marzouk, A; Tarek, S; Teama, SME, 2022)
"The calcium hydroxide mixed with lidocaine HCl can be beneficial in reducing postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis."9.41Effect of calcium hydroxide mixed with lidocaine hydrochloride on postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis: a preliminary randomized controlled prospective clinical trial. ( Arslan, H; Doğanay Yıldız, E; Taş, G; Tepecik, E; Topçuoğlu, HS, 2021)
"The aim of this randomized, double-blind clinical trial was to evaluate the effect of preoperative administration of intraligamentary injections of diclofenac sodium and dexamethasone on the anesthetic efficacy of 2% lidocaine given as an inferior alveolar nerve block in the endodontic management of symptomatic irreversible pulpitis."9.41Preoperative Intraligamentary Injection of Dexamethasone Can Improve the Anesthetic Success Rate of 2% Lidocaine during the Endodontic Management of Mandibular Molars with Symptomatic Irreversible Pulpitis. ( Aggarwal, V; Gupta, A; Hasija, M; Kumar, U; Meena, B; Saatchi, M; Singla, M, 2021)
"The use of nitrous/oxide plus the addition of lidocaine/clonidine for the IANB in teeth with symptomatic irreversible pulpitis resulted in no statistically significant difference in anesthetic success of the IANB."9.41Anesthetic Success Using Nitrous Oxide and a Combination of Lidocaine/Clonidine for the Inferior Alveolar Nerve Block and the Effects on Blood Pressure and Pulse in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind S ( Beck, M; Drum, M; Fowler, S; MacDonald, E; Nusstein, J; Reader, A, 2021)
"Preoperative administration of a combination of dexamethasone and ibuprofen improved the success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis."9.41Evaluating Combined Effect of Oral Premedication with Ibuprofen and Dexamethasone on Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial. ( Gill, GS; Jain, N; Kalra, T; Kumar, M; Singla, R, 2021)
"The objective of the current study was to compare the anaesthetic efficacy of supplemental intraligamentary (IL) injection of 4% articaine with that of 2% lidocaine in the mandibular first and second molars with irreversible pulpitis after an ineffective inferior alveolar nerve block injection (IANB) using the same anaesthetic in a randomised triple-blind clinical trial."9.41Anaesthetic Efficacy of 4% Articaine in Comparison with 2% Lidocaine as Intraligamentary Injections after an Ineffective Inferior Alveolar Nerve Block in Mandibular Molars with Irreversible Pulpitis: A Prospective Randomised Triple-Blind Clinical Trial. ( Akbarzadeh Baghban, A; Ashraf, H; Parhizkar, A; Pourmusavi, L; Shooshtari, E; Zargar, N, 2021)
"To establish the effects of submucosal tramadol, dexamethasone and articaine on the success of inferior alveolar nerve blocks (IANB) during root canal treatment of mandibular molars with symptomatic irreversible pulpitis (SIP)."9.41The effect of pre-operative submucosal administration of dexamethasone, tramadol, articaine on the success rate of inferior alveolar nerve block on mandibular molars with symptomatic irreversible pulpitis: A randomized, double-blind placebo-controlled cli ( Aksoy, F; Ege, B; Tosun, S, 2021)
"Aims To compare the anaesthetic efficacy of articaine, lidocaine and mepivacaine for buccal infiltration (BI) following lidocaine inferior alveolar nerve block (IANB) in mandibular posterior teeth with irreversible pulpitis."9.34Comparison of articaine, lidocaine and mepivacaine for buccal infiltration after inferior alveolar nerve block in mandibular posterior teeth with irreversible pulpitis. ( Gao, X; Meng, K, 2020)
"The purpose of this randomized, double-blind study was to evaluate the anesthetic efficacy of lidocaine-ketorolac administration by Inferior Alveolar Nerve Block (IANB) in patients with irreversible pulpitis."9.34Anesthetic Efficacy of Lidocaine/Ketorolac in Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial. ( Aggarwal, V; Faghihian, H; Faghihian, R; Khademi, A, 2020)
"This randomized, active-controlled, double-blind, prospective clinical trial evaluated the anesthetic efficacy of 2% lidocaine with 1:200,000 epinephrine versus an admixture of 2% lidocaine with 1:200,000 epinephrine and 1 mL of 4 mg dexamethasone (Twin mix) for inferior alveolar nerve blocks (IANBs) in patients with symptomatic irreversible pulpitis (SIP) of the mandibular molars."9.34Comparing the Efficacy of Twin Mix and Lidocaine for Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis. ( George, A; Kaushik, M; Mehra, N; Moturi, K; Podugu, UK; Sharma, R, 2020)
"8% lidocaine with 1 : 88 000 epinephrine resulted in a positive impact for the success of IANB in patients with a diagnosis of irreversible pulpitis related to mandibular molar teeth undergoing root canal treatment."9.34Effect of magnesium sulphate added to lidocaine on inferior alveolar nerve block success in patients with symptoms of irreversible pulpitis: a prospective, randomized clinical trial. ( Farnell, DJJ; Mousavi, SA; Sadaghiani, L; Shahnaseri, S; Vianna, ME; Zandian, A, 2020)
"For mandibular molars with irreversible pulpitis, addition of clonidine to lidocaine improved the success rate of IANB compared to a standard lidocaine/epinephrine solution."9.24Anaesthetic efficacy of lidocaine/clonidine for inferior alveolar nerve block in patients with irreversible pulpitis. ( Akhavan, A; Aminozarbian, MG; Davoudi, A; Mahdavian, P; Shadmehr, E, 2017)
"The objective of this study was to compare the anesthetic efficacy of 2% mepivacaine combined with 1:100,000 epinephrine with 2% lidocaine combined with 1:100,000 epinephrine during pulpectomy of mandibular posterior teeth in patients with irreversible pulpitis."9.22Comparison of the Anesthetic Efficacy of Mepivacaine and Lidocaine in Patients with Irreversible Pulpitis: A Double-blind Randomized Clinical Trial. ( Buscariolo, IA; Tortamano, IP; Visconti, RP, 2016)
"Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis."9.22Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016)
"The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of buffered with nonbuffered 2% lidocaine with 1:80,000 epinephrine solution for inferior alveolar nerve (IAN) block in patients with mandibular posterior teeth experiencing symptomatic irreversible pulpitis."9.20Effect of sodium bicarbonate-buffered lidocaine on the success of inferior alveolar nerve block for teeth with symptomatic irreversible pulpitis: a prospective, randomized double-blind study. ( Baghaei, B; Khademi, A; Noormohammadi, H; Saatchi, M, 2015)
"The purpose of this prospective, randomized, double-blind, placebo-controlled study was to compare the anesthetic efficacy between lidocaine with and without magnesium sulfate USP 50% for inferior alveolar nerve (IAN) blocks in patients with symptomatic irreversible pulpitis."9.20Comparison of anesthetic efficacy between lidocaine with and without magnesium sulfate USP 50% for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis. ( Kilaru, KR; Luke, AM; Sardar, P; Satish, SV; Shetty, KP, 2015)
"For mandibular posterior teeth, a 4% buffered lidocaine formulation did not result in a statistically significant increase in the success rate or a decrease in injection pain of the IAN block in patients with symptomatic irreversible pulpitis."9.20Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study. ( Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Schellenberg, J, 2015)
"8 mL of 2% lidocaine with different concentrations of epinephrine (1 : 80 000 and 1 : 200 000) in patients with symptomatic irreversible pulpitis."9.19Comparison of the anaesthetic efficacy of epinephrine concentrations (1 : 80 000 and 1 : 200 000) in 2% lidocaine for inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a randomized, double-blind clinical trial. ( Aggarwal, V; Kohli, S; Miglani, S; Singla, M, 2014)
"A combination dose of 1000 mg acetaminophen/10 mg hydrocodone given 60 minutes before the administration of the IAN block did not result in a statistically significant increase in anesthetic success for mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis."9.19Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study. ( Beck, M; Drum, M; Fullmer, S; Nusstein, J; Reader, A, 2014)
"Supplementing an incomplete articaine IANB with articaine infiltration raises the anesthetic success more effectively compared with lidocaine in mandibular molars with irreversible pulpitis."9.17Efficacy of articaine versus lidocaine in block and infiltration anesthesia administered in teeth with irreversible pulpitis: a prospective, randomized, double-blind study. ( Ashraf, H; Dianat, O; Kazem, M; Noghrehkar, F, 2013)
"The aim of this study was to compare 2 kinds of anti-inflammatory medicines (ie, dexamethasone and ibuprofen) with a placebo according to their effects on the success rates of an inferior alveolar nerve block (IANB) for the endodontic treatment of mandibular molars with irreversible pulpitis."9.17Effect of premedication with ibuprofen and dexamethasone on success rate of inferior alveolar nerve block for teeth with asymptomatic irreversible pulpitis: a randomized clinical trial. ( Abdolrahimi, M; Mokhtari, H; Narimani, S; Nezafati, S; Rahimi, S; Shahi, S; Yavari, HR, 2013)
"There was no significant difference in efficacy between 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving anesthesia in maxillary teeth with irreversible pulpitis after buccal infiltration."9.16A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis. ( Kanaa, MD; Meechan, JG; Whitworth, JM, 2012)
"5% bupivacaine with 1:200,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth."9.16Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar. ( Carnaval, TG; Horliana, AC; Lanfredi, CB; Rocha, RG; Sampaio, RM; Tortamano, IP, 2012)
"5 mol/L mannitol for inferior alveolar nerve (IAN) blocks in patients experiencing symptomatic irreversible pulpitis."9.16Anesthetic efficacy of combinations of 0.5 mol/L mannitol and lidocaine with epinephrine for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis. ( Beck, M; Drum, M; Kiser, R; Kreimer, T; Nusstein, J; Reader, A, 2012)
"Patients who received bupivacaine as the anesthetic agent for single-visit endodontic treatment of irreversible pulpitis in mandibular molars had significantly less early postoperative pain and used fewer analgesics than those who had lidocaine as the anesthetic."9.16Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Reza Forghani, F; Yosefi, MH, 2012)
"To determine the effect of administration of pre-operative lornoxicam (LNX) or diclofenac potassium (DP) on the success of inferior alveolar nerve blocks (IANB) in patients with irreversible pulpitis in a double-blind randomised controlled trial."9.15The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial. ( Gutmann, JL; Prasanna, N; Subbarao, CV, 2011)
"Forty patients with irreversible pulpitis in first premolar or first molar were divided into 4 study groups and received buccal infiltration of either 4% articaine or 2% lidocaine in a double-blind manner."9.14Comparison of anesthetic efficacy of 4% articaine and 2% lidocaine for maxillary buccal infiltration in patients with irreversible pulpitis. ( Kavitha, M; Loganathan, CS; Padmini, G; Srinivasan, N, 2009)
"The purpose of the present study was to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth."9.14A comparison of the anesthetic efficacy of articaine and lidocaine in patients with irreversible pulpitis. ( Armonia, PL; Buscariolo, IA; Costa, CG; Siviero, M; Tortamano, IP, 2009)
"Although supplemental buccal and lingual infiltrations of 4% articaine or 2% lidocaine increased the success rate of the inferior alveolar nerve block in patients with irreversible pulpitis, none of the techniques provided acceptable success rates."9.14Anesthetic efficacy of supplemental buccal and lingual infiltrations of articaine and lidocaine after an inferior alveolar nerve block in patients with irreversible pulpitis. ( Aggarwal, V; Jain, A; Kabi, D, 2009)
"Preoperative administration of ibuprofen or ketorolac has no significant effect on success rate of inferior alveolar nerve block in patients with irreversible pulpitis."9.14Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri ( Aggarwal, V; Kabi, D; Singla, M, 2010)
"One hundred endodontic emergency patients diagnosed with irreversible pulpitis of a mandibular posterior tooth randomly received, in a double-blind manner, identical capsules of either 800 mg ibuprofen or placebo 45 minutes before the administration of a conventional IAN block."9.14Effect of preoperative ibuprofen on the success of the inferior alveolar nerve block in patients with irreversible pulpitis. ( Beck, M; Drum, M; Nusstein, J; Oleson, M; Reader, A, 2010)
"In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia."9.14The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010)
"The aim of this randomized, double-blinded study was to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine (AE) with 2% lidocaine with 1:100,000 epinephrine (LE) for Gow-Gates blocks and maxillary infiltrations in patients experiencing irreversible pulpitis in mandibular and maxillary posterior teeth."9.13Anesthetic efficacy of the Gow-Gates injection and maxillary infiltration with articaine and lidocaine for irreversible pulpitis. ( Flax, M; Murray, PE; Namerow, K; Sherman, MG, 2008)
"The purpose of this prospective, randomized, single-blind study was to compare the anesthetic efficacy of lidocaine with epinephrine to lidocaine plus meperidine with epinephrine for inferior alveolar nerve blocks (IAN) in patients with mandibular posterior teeth experiencing irreversible pulpitis."9.12Anesthetic efficacy of lidocaine/meperidine for inferior alveolar nerve blocks in patients with irreversible pulpitis. ( Beck, M; Bigby, J; Nusstein, J; Reader, A, 2007)
"To examine whether an intra-oral injection of a nonsteroidal anti-inflammatory drug (ketorolac), in association with conventional local anaesthetic techniques, would improve the pulp extirpation rate in teeth with irreversible pulpitis."9.11The use of an intra-oral injection of ketorolac in the treatment of irreversible pulpitis. ( Dorman, ML; Girdler, NM; Mellor, AC, 2005)
"Articaine is more effective than lidocaine for local anaesthesia of teeth with irreversible pulpitis undergoing root canal treatment."9.05Is articaine more effective than lidocaine in patients with irreversible pulpitis? An umbrella review. ( Dummer, PMH; Duncan, HF; Nagendrababu, V; Nekoofar, MH; Pulikkotil, SJ; Veettil, SK; Whitworth, J, 2020)
"This study aimed to compare the effectiveness of mepivacaine and lidocaine for pulpal anaesthesia and pain control when administered via an inferior alveolar nerve block during the root canal treatment of mandibular molars in patients with symptomatic irreversible pulpitis."8.98Is mepivacaine as effective as lidocaine during inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis? A systematic review and meta-analysis. ( Cericato, GO; Franco, A; Paranhos, LR; Ribeiro, MAG; Vieira, WA, 2018)
"The aim was to assess the efficacy and safety of articaine compared with lidocaine for irreversible pulpitis (IP) treatment."8.93Efficacy and safety of articaine versus lidocaine for irreversible pulpitis treatment: A systematic review and meta-analysis of randomised controlled trials. ( Kou, L; Li, C; Liu, W; Shen, J; Su, N; Wang, H, 2016)
"The purpose of this prospective study was to determine the effect of a combination of nitrous oxide/oxygen and 1 set of supplemental intraligamentary/periodontal ligament (PDL) injections followed by a second set of PDL injections on anesthetic success in patients with symptomatic irreversible pulpitis (SIP)."8.02Effect of a Combination of Nitrous Oxide and Intraligamentary Injection on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis. ( Chen, LS; Drum, M; Fowler, S; Guo, X; Nusstein, J; Reader, A, 2021)
"The aim of the present study is to compare the efficacy of additional 100 mg/2 ml tramadol and 40 mg/2 ml lidocaine applications on the anesthetic success of inferior alveolar nerve block (IANB) in mandibular molars with symptomatic irreversible pulpitis (MM-SIP)."7.96Efficacy of submucosal tramadol and lidocaine on success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis. ( Aksoy, F; Ege, B, 2020)
"Does articaine provide an advantage over lidocaine in patients with symptomatic irreversible pulpitis? A systematic review and meta-analysis."7.85In Patients With Symptomatic Irreversible Pulpitis, Articaine is 3.6 Times More Efficacious Than Lidocaine in Achieving Anesthetic Success When Used for Supplementary Infiltration After Mandibular Block Anesthesia. ( Botero, TM; Peters, MC, 2017)
"Effect of buffered 4% lidocaine on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind study."7.83Buffered Lidocaine With Sodium Bicarbonate did not Increase Inferior Alveolar Nerve Block Success Rate in Patients Having Symptomatic Irreversible Pulpitis. ( Parirokh, M, 2016)
"The purpose of this study was to determine the anesthetic efficacy of a supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in teeth diagnosed with irreversible pulpitis."7.70Anesthetic efficacy of the supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in irreversible pulpitis. ( Beck, M; Meyers, WJ; Nist, R; Nusstein, J; Reader, A, 1998)
"To determine the efficacy of a supplemental intraosseous injection of 3% mepivacaine in mandibular posterior teeth with irreversible pulpitis."7.69Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis. ( Beck, M; Nist, R; Reader, A; Reisman, D; Weaver, J, 1997)
"Furthermore, postoperative pain in the ketamine group was significantly lower (P = 0."6.76The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis. ( Ebtehaj, I; Kaviani, N; Khademi, A; Mohammadi, Z, 2011)
"The purpose of this double-blind clinical trial was to compare the effect of preoperative tramadol 50 mg, tramadol 100 mg, ibuprofen 600 mg, ibuprofen 600 mg/acetaminophen 1000 mg or placebo 60 min before the administration of inferior alveolar nerve blocks (IANB) of mandibular teeth in patients experiencing symptomatic irreversible pulpitis (SIP)."5.69Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. ( Badr, AE; Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023)
"Premedication with meloxicam, ketorolac, dexamethasone, and ibuprofen increased the efficacy of IANB in mandibular molars with symptomatic irreversible pulpitis."5.69Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial. ( Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023)
"This randomized double-blinded trial aimed to compare the anesthetic success of inferior alveolar nerve blocks (IANBs) with 2% lidocaine in mandibular molars with symptomatic irreversible pulpitis (SIP) after oral premedication of prednisolone, dexamethasone, and ketorolac with placebo."5.69Effect of Preoperative Oral Steroids in Comparison to Anti-inflammatory on Anesthetic Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis-A Double-blinded Randomized Clinical Trial. ( Hegde, V; Kulkarni, V; Nagendrababu, V; Setzer, FC; Shaikh, S; Shanmugasundaram, S; Suresh, N, 2023)
"Successful anesthesia (defined as no or mild pain during any of steps and no need for additional injection) is obtained in 12% of patients in the lidocaine group, while DEX-lidocaine group increased the success rate of IANB to 72% (p-value = 0."5.51Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial. ( Moshari, A; Moshari, M; Vahedi, Z, 2022)
"The aim of this study was to assess inferior alveolar nerve block (IANB) success of 2% mepivacaine (Scandonest 2%, Septodont, France) and 4% articaine (Septanest 4%, Septodont) in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation."5.51Inferior alveolar nerve block success of 2% mepivacaine versus 4% articaine in patients with symptomatic irreversible pulpitis in mandibular molars: A randomized double-blind single-centre clinical trial. ( Amin, SAW; Bedier, MM; El Boghdadi, RM; Ezzat, K; Fouda, MY; Gawdat, SI; Habib, MFOM; Marzouk, A; Tarek, S; Teama, SME, 2022)
" Five RCTs suggest that both benzocaine 10% and 20% may increase the number of people experiencing pain reduction compared with placebo when managing acute irreversible pulpitis (low certainty)."5.41Injectable and topical local anesthetics for acute dental pain: 2 systematic reviews. ( Azab, M; Brignardello-Petersen, R; Carrasco-Labra, A; Diaz Martinez, JP; He, L; Hersh, EV; Ibrahim, S; Miroshnychenko, A; Moore, PA; Polk, DE; Roldan, Y; Tamilselvan, D; Tampi, M; Urquhart, O, 2023)
"The calcium hydroxide mixed with lidocaine HCl can be beneficial in reducing postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis."5.41Effect of calcium hydroxide mixed with lidocaine hydrochloride on postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis: a preliminary randomized controlled prospective clinical trial. ( Arslan, H; Doğanay Yıldız, E; Taş, G; Tepecik, E; Topçuoğlu, HS, 2021)
"The aim of this randomized, double-blind clinical trial was to evaluate the effect of preoperative administration of intraligamentary injections of diclofenac sodium and dexamethasone on the anesthetic efficacy of 2% lidocaine given as an inferior alveolar nerve block in the endodontic management of symptomatic irreversible pulpitis."5.41Preoperative Intraligamentary Injection of Dexamethasone Can Improve the Anesthetic Success Rate of 2% Lidocaine during the Endodontic Management of Mandibular Molars with Symptomatic Irreversible Pulpitis. ( Aggarwal, V; Gupta, A; Hasija, M; Kumar, U; Meena, B; Saatchi, M; Singla, M, 2021)
"The use of nitrous/oxide plus the addition of lidocaine/clonidine for the IANB in teeth with symptomatic irreversible pulpitis resulted in no statistically significant difference in anesthetic success of the IANB."5.41Anesthetic Success Using Nitrous Oxide and a Combination of Lidocaine/Clonidine for the Inferior Alveolar Nerve Block and the Effects on Blood Pressure and Pulse in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind S ( Beck, M; Drum, M; Fowler, S; MacDonald, E; Nusstein, J; Reader, A, 2021)
"Preoperative administration of a combination of dexamethasone and ibuprofen improved the success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis."5.41Evaluating Combined Effect of Oral Premedication with Ibuprofen and Dexamethasone on Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial. ( Gill, GS; Jain, N; Kalra, T; Kumar, M; Singla, R, 2021)
"The objective of the current study was to compare the anaesthetic efficacy of supplemental intraligamentary (IL) injection of 4% articaine with that of 2% lidocaine in the mandibular first and second molars with irreversible pulpitis after an ineffective inferior alveolar nerve block injection (IANB) using the same anaesthetic in a randomised triple-blind clinical trial."5.41Anaesthetic Efficacy of 4% Articaine in Comparison with 2% Lidocaine as Intraligamentary Injections after an Ineffective Inferior Alveolar Nerve Block in Mandibular Molars with Irreversible Pulpitis: A Prospective Randomised Triple-Blind Clinical Trial. ( Akbarzadeh Baghban, A; Ashraf, H; Parhizkar, A; Pourmusavi, L; Shooshtari, E; Zargar, N, 2021)
"To establish the effects of submucosal tramadol, dexamethasone and articaine on the success of inferior alveolar nerve blocks (IANB) during root canal treatment of mandibular molars with symptomatic irreversible pulpitis (SIP)."5.41The effect of pre-operative submucosal administration of dexamethasone, tramadol, articaine on the success rate of inferior alveolar nerve block on mandibular molars with symptomatic irreversible pulpitis: A randomized, double-blind placebo-controlled cli ( Aksoy, F; Ege, B; Tosun, S, 2021)
"Aims To compare the anaesthetic efficacy of articaine, lidocaine and mepivacaine for buccal infiltration (BI) following lidocaine inferior alveolar nerve block (IANB) in mandibular posterior teeth with irreversible pulpitis."5.34Comparison of articaine, lidocaine and mepivacaine for buccal infiltration after inferior alveolar nerve block in mandibular posterior teeth with irreversible pulpitis. ( Gao, X; Meng, K, 2020)
"The administration of bupivacaine anesthetic agent for inferior alveolar nerve block (IANB) injections can be a better and appropriate pain management aid as compared to lidocaine during root canal treatment of patient with symptomatic irreversible pulpitis."5.34Determination of Anesthetic Efficacy of Lidocaine Versus Bupivacaine in Single Visit Root Canal Treatment. ( Ahmed, MA; Ghani, B; Jouhar, R, 2020)
"The purpose of this randomized, double-blind study was to evaluate the anesthetic efficacy of lidocaine-ketorolac administration by Inferior Alveolar Nerve Block (IANB) in patients with irreversible pulpitis."5.34Anesthetic Efficacy of Lidocaine/Ketorolac in Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial. ( Aggarwal, V; Faghihian, H; Faghihian, R; Khademi, A, 2020)
"This randomized, active-controlled, double-blind, prospective clinical trial evaluated the anesthetic efficacy of 2% lidocaine with 1:200,000 epinephrine versus an admixture of 2% lidocaine with 1:200,000 epinephrine and 1 mL of 4 mg dexamethasone (Twin mix) for inferior alveolar nerve blocks (IANBs) in patients with symptomatic irreversible pulpitis (SIP) of the mandibular molars."5.34Comparing the Efficacy of Twin Mix and Lidocaine for Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis. ( George, A; Kaushik, M; Mehra, N; Moturi, K; Podugu, UK; Sharma, R, 2020)
"8% lidocaine with 1 : 88 000 epinephrine resulted in a positive impact for the success of IANB in patients with a diagnosis of irreversible pulpitis related to mandibular molar teeth undergoing root canal treatment."5.34Effect of magnesium sulphate added to lidocaine on inferior alveolar nerve block success in patients with symptoms of irreversible pulpitis: a prospective, randomized clinical trial. ( Farnell, DJJ; Mousavi, SA; Sadaghiani, L; Shahnaseri, S; Vianna, ME; Zandian, A, 2020)
"One hundred six adult patients with symptomatic irreversible pulpitis in a mandibular first or second molar received an initial inferior alveolar nerve block with 2% lidocaine with 1:80,000 epinephrine."5.30Efficacy of Articaine Versus Lidocaine Administered as Supplementary Intraligamentary Injection after a Failed Inferior Alveolar Nerve Block: A Randomized Double-blind Study. ( Aggarwal, V; Kohli, S; Miglani, S; Singla, M, 2019)
"For mandibular molars with irreversible pulpitis, addition of clonidine to lidocaine improved the success rate of IANB compared to a standard lidocaine/epinephrine solution."5.24Anaesthetic efficacy of lidocaine/clonidine for inferior alveolar nerve block in patients with irreversible pulpitis. ( Akhavan, A; Aminozarbian, MG; Davoudi, A; Mahdavian, P; Shadmehr, E, 2017)
"To assess the efficacy of incorporating additives into lidocaine in the success rate of IANB for teeth with the diagnosis of normal pulp (NP) or symptomatic irreversible pulpitis (SIP)."5.22Anaesthetic efficacy of incorporating different additives into lidocaine for the inferior alveolar nerve block: A systematic review with meta-analysis and trial sequential analysis. ( Aggarwal, V; Iranmanesh, P; Khademi, A; Khazaei, S; Kolahi, J; Nili, M; Saatchi, M, 2022)
"To compare the anesthetic efficacy of buccal infiltration (BI) using 4% articaine vs 4% articaine or 2% lidocaine inferior alveolar nerve block (IANB) for mandibular molars with symptomatic irreversible pulpitis."5.22EFFICACY OF 4% ARTICAINE BUCCAL INFILTRATION VERSUS INFERIOR ALVEOLAR NERVE BLOCK FOR MANDIBULAR MOLARS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. ( Abuiriban, RW; Al-Hamed, FS; Almadhoon, HW; Almassri, H, 2022)
"The combination of ibuprofen/paracetamol, taken immediately after initial endodontic therapy and root canal preparation in teeth with irreversible pulpitis, reduced post-endodontic pain (ClinicalTrials."5.22Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. ( Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM, 2016)
"The objective of this study was to compare the anesthetic efficacy of 2% mepivacaine combined with 1:100,000 epinephrine with 2% lidocaine combined with 1:100,000 epinephrine during pulpectomy of mandibular posterior teeth in patients with irreversible pulpitis."5.22Comparison of the Anesthetic Efficacy of Mepivacaine and Lidocaine in Patients with Irreversible Pulpitis: A Double-blind Randomized Clinical Trial. ( Buscariolo, IA; Tortamano, IP; Visconti, RP, 2016)
"Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis."5.22Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016)
"The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of buffered with nonbuffered 2% lidocaine with 1:80,000 epinephrine solution for inferior alveolar nerve (IAN) block in patients with mandibular posterior teeth experiencing symptomatic irreversible pulpitis."5.20Effect of sodium bicarbonate-buffered lidocaine on the success of inferior alveolar nerve block for teeth with symptomatic irreversible pulpitis: a prospective, randomized double-blind study. ( Baghaei, B; Khademi, A; Noormohammadi, H; Saatchi, M, 2015)
"The purpose of this prospective, randomized, double-blind, placebo-controlled study was to compare the anesthetic efficacy between lidocaine with and without magnesium sulfate USP 50% for inferior alveolar nerve (IAN) blocks in patients with symptomatic irreversible pulpitis."5.20Comparison of anesthetic efficacy between lidocaine with and without magnesium sulfate USP 50% for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis. ( Kilaru, KR; Luke, AM; Sardar, P; Satish, SV; Shetty, KP, 2015)
"For mandibular posterior teeth, a 4% buffered lidocaine formulation did not result in a statistically significant increase in the success rate or a decrease in injection pain of the IAN block in patients with symptomatic irreversible pulpitis."5.20Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study. ( Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Schellenberg, J, 2015)
"8 mL of 2% lidocaine with different concentrations of epinephrine (1 : 80 000 and 1 : 200 000) in patients with symptomatic irreversible pulpitis."5.19Comparison of the anaesthetic efficacy of epinephrine concentrations (1 : 80 000 and 1 : 200 000) in 2% lidocaine for inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a randomized, double-blind clinical trial. ( Aggarwal, V; Kohli, S; Miglani, S; Singla, M, 2014)
"A combination dose of 1000 mg acetaminophen/10 mg hydrocodone given 60 minutes before the administration of the IAN block did not result in a statistically significant increase in anesthetic success for mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis."5.19Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study. ( Beck, M; Drum, M; Fullmer, S; Nusstein, J; Reader, A, 2014)
"Supplementing an incomplete articaine IANB with articaine infiltration raises the anesthetic success more effectively compared with lidocaine in mandibular molars with irreversible pulpitis."5.17Efficacy of articaine versus lidocaine in block and infiltration anesthesia administered in teeth with irreversible pulpitis: a prospective, randomized, double-blind study. ( Ashraf, H; Dianat, O; Kazem, M; Noghrehkar, F, 2013)
"The aim of this study was to compare 2 kinds of anti-inflammatory medicines (ie, dexamethasone and ibuprofen) with a placebo according to their effects on the success rates of an inferior alveolar nerve block (IANB) for the endodontic treatment of mandibular molars with irreversible pulpitis."5.17Effect of premedication with ibuprofen and dexamethasone on success rate of inferior alveolar nerve block for teeth with asymptomatic irreversible pulpitis: a randomized clinical trial. ( Abdolrahimi, M; Mokhtari, H; Narimani, S; Nezafati, S; Rahimi, S; Shahi, S; Yavari, HR, 2013)
"There was no significant difference in efficacy between 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving anesthesia in maxillary teeth with irreversible pulpitis after buccal infiltration."5.16A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis. ( Kanaa, MD; Meechan, JG; Whitworth, JM, 2012)
"The objective of this study was to compare the efficacy of supplementary repeat inferior alveolar nerve block with 2% lidocaine and epinephrine, buccal infiltration with 4% articaine with epinephrine, intraligamentary injection, or intraosseous injection (both with 2% lidocaine with epinephrine) after failed inferior alveolar nerve block (IANB) for securing pain-free treatment in patients experiencing irreversible pulpitis in mandibular permanent teeth."5.16A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth. ( Kanaa, MD; Meechan, JG; Whitworth, JM, 2012)
"In this single-blind randomized clinical trial, 40 patients (22 women, 18 men) with irreversible pulpitis who had experienced unsuccessful pain management by inferior alveolar nerve block with 2% lidocaine and 1 : 100 000 epinephrine were selected."5.16Comparison of the anaesthetic efficacy of and heart rate changes after periodontal ligament or intraosseous X-Tip injection in mandibular molars: a randomized controlled clinical trial. ( Afkhami, F; Forghani, M; Ghoddusi, J; Marouzi, P; Sharifi, E; Zarei, M, 2012)
"5% bupivacaine with 1:200,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth."5.16Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar. ( Carnaval, TG; Horliana, AC; Lanfredi, CB; Rocha, RG; Sampaio, RM; Tortamano, IP, 2012)
"5 mol/L mannitol for inferior alveolar nerve (IAN) blocks in patients experiencing symptomatic irreversible pulpitis."5.16Anesthetic efficacy of combinations of 0.5 mol/L mannitol and lidocaine with epinephrine for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis. ( Beck, M; Drum, M; Kiser, R; Kreimer, T; Nusstein, J; Reader, A, 2012)
"Patients who received bupivacaine as the anesthetic agent for single-visit endodontic treatment of irreversible pulpitis in mandibular molars had significantly less early postoperative pain and used fewer analgesics than those who had lidocaine as the anesthetic."5.16Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Reza Forghani, F; Yosefi, MH, 2012)
"To determine the effect of administration of pre-operative lornoxicam (LNX) or diclofenac potassium (DP) on the success of inferior alveolar nerve blocks (IANB) in patients with irreversible pulpitis in a double-blind randomised controlled trial."5.15The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial. ( Gutmann, JL; Prasanna, N; Subbarao, CV, 2011)
"The purpose of this study was to evaluate and compare the anesthetic efficacy of posterior superior alveolar (PSA) nerve blocks, buccal infiltrations, and buccal plus palatal infiltrations with 2% lidocaine with 1:200,000 epinephrine in maxillary first molars with irreversible pulpitis."5.15A prospective, randomized, single-blind comparative evaluation of anesthetic efficacy of posterior superior alveolar nerve blocks, buccal infiltrations, and buccal plus palatal infiltrations in patients with irreversible pulpitis. ( Aggarwal, V; Ansari, I; Kohli, S; Miglani, S; Singla, M, 2011)
"Forty patients with irreversible pulpitis in first premolar or first molar were divided into 4 study groups and received buccal infiltration of either 4% articaine or 2% lidocaine in a double-blind manner."5.14Comparison of anesthetic efficacy of 4% articaine and 2% lidocaine for maxillary buccal infiltration in patients with irreversible pulpitis. ( Kavitha, M; Loganathan, CS; Padmini, G; Srinivasan, N, 2009)
"The purpose of the present study was to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth."5.14A comparison of the anesthetic efficacy of articaine and lidocaine in patients with irreversible pulpitis. ( Armonia, PL; Buscariolo, IA; Costa, CG; Siviero, M; Tortamano, IP, 2009)
"Although supplemental buccal and lingual infiltrations of 4% articaine or 2% lidocaine increased the success rate of the inferior alveolar nerve block in patients with irreversible pulpitis, none of the techniques provided acceptable success rates."5.14Anesthetic efficacy of supplemental buccal and lingual infiltrations of articaine and lidocaine after an inferior alveolar nerve block in patients with irreversible pulpitis. ( Aggarwal, V; Jain, A; Kabi, D, 2009)
"Preoperative administration of ibuprofen or ketorolac has no significant effect on success rate of inferior alveolar nerve block in patients with irreversible pulpitis."5.14Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri ( Aggarwal, V; Kabi, D; Singla, M, 2010)
"One hundred endodontic emergency patients diagnosed with irreversible pulpitis of a mandibular posterior tooth randomly received, in a double-blind manner, identical capsules of either 800 mg ibuprofen or placebo 45 minutes before the administration of a conventional IAN block."5.14Effect of preoperative ibuprofen on the success of the inferior alveolar nerve block in patients with irreversible pulpitis. ( Beck, M; Drum, M; Nusstein, J; Oleson, M; Reader, A, 2010)
"In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia."5.14The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010)
"The aim of this randomized, double-blinded study was to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine (AE) with 2% lidocaine with 1:100,000 epinephrine (LE) for Gow-Gates blocks and maxillary infiltrations in patients experiencing irreversible pulpitis in mandibular and maxillary posterior teeth."5.13Anesthetic efficacy of the Gow-Gates injection and maxillary infiltration with articaine and lidocaine for irreversible pulpitis. ( Flax, M; Murray, PE; Namerow, K; Sherman, MG, 2008)
"The purpose of this prospective, randomized, single-blind study was to compare the anesthetic efficacy of lidocaine with epinephrine to lidocaine plus meperidine with epinephrine for inferior alveolar nerve blocks (IAN) in patients with mandibular posterior teeth experiencing irreversible pulpitis."5.12Anesthetic efficacy of lidocaine/meperidine for inferior alveolar nerve blocks in patients with irreversible pulpitis. ( Beck, M; Bigby, J; Nusstein, J; Reader, A, 2007)
"The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine to 2% lidocaine with 1:100,000 epinephrine for inferior alveolar nerve blocks in patients experiencing irreversible pulpitis in mandibular posterior teeth."5.11Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis. ( Beck, M; Claffey, E; Nusstein, J; Reader, A; Weaver, J, 2004)
"To examine whether an intra-oral injection of a nonsteroidal anti-inflammatory drug (ketorolac), in association with conventional local anaesthetic techniques, would improve the pulp extirpation rate in teeth with irreversible pulpitis."5.11The use of an intra-oral injection of ketorolac in the treatment of irreversible pulpitis. ( Dorman, ML; Girdler, NM; Mellor, AC, 2005)
"The purpose of this prospective, double-blind, randomized study was to evaluate pain reduction using an intraosseous injection of slow-releasing methylprednisolone in teeth with irreversible pulpitis."5.09Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol. ( Beck, M; Gallatin, E; Nist, R; Reader, A, 2000)
"Articaine is more effective than lidocaine for local anaesthesia of teeth with irreversible pulpitis undergoing root canal treatment."5.05Is articaine more effective than lidocaine in patients with irreversible pulpitis? An umbrella review. ( Dummer, PMH; Duncan, HF; Nagendrababu, V; Nekoofar, MH; Pulikkotil, SJ; Veettil, SK; Whitworth, J, 2020)
"Very low- to moderate-quality evidence suggests intraosseous injection using 2% lidocaine with 1:100,000 epinephrine or 4% articaine with 1:100,000 epinephrine or buccal and lingual infiltrations of 4% articaine with 1:100,000 epinephrine are superior strategies to achieve pulpal anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis."5.01Efficacy and Safety of Pulpal Anesthesia Strategies during Endodontic Treatment of Permanent Mandibular Molars with Symptomatic Irreversible Pulpitis: A Systematic Review and Network Meta-analysis. ( Azarpazhooh, A; Beyene, J; Lighvan, NL; Shah, PS; Yarascavitch, C; Zanjir, M, 2019)
"This study aimed to compare the effectiveness of mepivacaine and lidocaine for pulpal anaesthesia and pain control when administered via an inferior alveolar nerve block during the root canal treatment of mandibular molars in patients with symptomatic irreversible pulpitis."4.98Is mepivacaine as effective as lidocaine during inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis? A systematic review and meta-analysis. ( Cericato, GO; Franco, A; Paranhos, LR; Ribeiro, MAG; Vieira, WA, 2018)
"The aim was to assess the efficacy and safety of articaine compared with lidocaine for irreversible pulpitis (IP) treatment."4.93Efficacy and safety of articaine versus lidocaine for irreversible pulpitis treatment: A systematic review and meta-analysis of randomised controlled trials. ( Kou, L; Li, C; Liu, W; Shen, J; Su, N; Wang, H, 2016)
"The purpose of this prospective study was to determine the effect of a combination of nitrous oxide/oxygen and 1 set of supplemental intraligamentary/periodontal ligament (PDL) injections followed by a second set of PDL injections on anesthetic success in patients with symptomatic irreversible pulpitis (SIP)."4.02Effect of a Combination of Nitrous Oxide and Intraligamentary Injection on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis. ( Chen, LS; Drum, M; Fowler, S; Guo, X; Nusstein, J; Reader, A, 2021)
"The aim of the present study is to compare the efficacy of additional 100 mg/2 ml tramadol and 40 mg/2 ml lidocaine applications on the anesthetic success of inferior alveolar nerve block (IANB) in mandibular molars with symptomatic irreversible pulpitis (MM-SIP)."3.96Efficacy of submucosal tramadol and lidocaine on success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis. ( Aksoy, F; Ege, B, 2020)
"Does articaine provide an advantage over lidocaine in patients with symptomatic irreversible pulpitis? A systematic review and meta-analysis."3.85In Patients With Symptomatic Irreversible Pulpitis, Articaine is 3.6 Times More Efficacious Than Lidocaine in Achieving Anesthetic Success When Used for Supplementary Infiltration After Mandibular Block Anesthesia. ( Botero, TM; Peters, MC, 2017)
"Effect of buffered 4% lidocaine on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind study."3.83Buffered Lidocaine With Sodium Bicarbonate did not Increase Inferior Alveolar Nerve Block Success Rate in Patients Having Symptomatic Irreversible Pulpitis. ( Parirokh, M, 2016)
"The purpose of this retrospective study was to determine the incidence of missed inferior alveolar nerve (IAN) blocks by using a 1- or 2-cartridge volume of 2% lidocaine with 1:100,000 epinephrine in vital asymptomatic teeth and in emergency patients with symptomatic irreversible pulpitis."3.81Incidence of missed inferior alveolar nerve blocks in vital asymptomatic subjects and in patients with symptomatic irreversible pulpitis. ( Beck, M; Fowler, S; Reader, A, 2015)
"8 mL 2% lidocaine with 1:100,000 epinephrine in patients presenting with symptomatic irreversible pulpitis."3.79Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis? ( Fowler, S; Reader, A, 2013)
"One hundred twelve emergency patients with irreversible pulpitis received long buccal nerve block injections using 2% lidocaine with 1:100,000 epinephrine."3.77Long buccal nerve block injection pain in patients with irreversible pulpitis. ( Beck, M; Drum, M; Reader, A, 2011)
"The purpose of this study was to determine the anesthetic efficacy of a supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in teeth diagnosed with irreversible pulpitis."3.70Anesthetic efficacy of the supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in irreversible pulpitis. ( Beck, M; Meyers, WJ; Nist, R; Nusstein, J; Reader, A, 1998)
"To determine the efficacy of a supplemental intraosseous injection of 3% mepivacaine in mandibular posterior teeth with irreversible pulpitis."3.69Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis. ( Beck, M; Nist, R; Reader, A; Reisman, D; Weaver, J, 1997)
"The lip numbness time of lidocaine was 3."3.30Articaine versus lidocaine inferior alveolar nerve block in posterior mandible implant surgeries: a randomized controlled trial. ( Alpan, AL; Gülnahar, E; Gülnahar, Y, 2023)
"Irreversible pulpitis is a highly painful inflammatory condition of the dental pulp."3.11Anaesthetic efficacy and influence on cardiovascular parameters change of intraosseous computerised anaesthesia versus inferior alveolar nerve block anaesthesia in acute irreversible pulpitis of mandibular molars: study protocol for a prospective randomis ( Clouet, R; Del Valle, GA; Gaudin, A; Laham, A; Prud'homme, T, 2022)
"Furthermore, postoperative pain in the ketamine group was significantly lower (P = 0."2.76The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis. ( Ebtehaj, I; Kaviani, N; Khademi, A; Mohammadi, Z, 2011)
"The purpose of this study was to determine the anesthetic effectiveness of the supplemental intraligamentary injection, administered with a computer-controlled local anesthetic delivery system, in mandibular posterior teeth diagnosed with irreversible pulpitis when the conventional inferior alveolar nerve block failed."2.71Anesthetic effectiveness of the supplemental intraligamentary injection, administered with a computer-controlled local anesthetic delivery system, in patients with irreversible pulpitis. ( Beck, M; Claffey, E; Nusstein, J; Reader, A; Weaver, J, 2005)
" There was no statistically significance in adverse events between two groups."2.50Efficacy and safety of bupivacaine versus lidocaine in dental treatments: a meta-analysis of randomised controlled trials. ( Huang, Y; Liao, S; Su, N; Wang, H; Yang, S; Zhang, S, 2014)

Research

Studies (140)

TimeframeStudies, this research(%)All Research%
pre-19905 (3.57)18.7374
1990's5 (3.57)18.2507
2000's16 (11.43)29.6817
2010's59 (42.14)24.3611
2020's55 (39.29)2.80

Authors

AuthorsStudies
Gurucharan, I1
Sekar, M1
Balasubramanian, S1
Narasimhan, S1
Chen, LS1
Nusstein, J13
Drum, M9
Fowler, S6
Reader, A18
Guo, X1
Yu, J1
Liu, S1
Zhang, X1
Zhang, IL1
Kratunova, E1
Sha, A1
Marion, I1
da Fonseca, MA1
Han, M1
Saber, SM1
Hashem, AA1
Khalil, DM1
Pirani, C1
Ordinola-Zapata, R1
Parirokh, M5
Abbott, PV7
Vahedi, Z1
Moshari, A1
Moshari, M1
Iranmanesh, P1
Khazaei, S1
Nili, M1
Saatchi, M3
Aggarwal, V15
Kolahi, J1
Khademi, A4
Zhang, F1
Wu, S1
Qu, M1
Zhou, L1
Almadhoon, HW1
Abuiriban, RW1
Almassri, H1
Al-Hamed, FS1
Elnaghy, AM4
Elshazli, AH4
Badr, AE1
Elsaka, SE4
Habib, MFOM1
Tarek, S1
Teama, SME1
Ezzat, K1
El Boghdadi, RM1
Marzouk, A1
Fouda, MY1
Gawdat, SI1
Bedier, MM1
Amin, SAW1
Gandhi, N1
Shah, N1
Wahjuningrum, DA1
Purnomo, S1
Nooshian, R1
Arora, S1
Pawar, AM1
Laham, A3
Clouet, R3
Del Valle, GA2
Gaudin, A3
Prud'homme, T3
Lamira, JM2
Wilson, CS2
Leppek, NC2
Orr, CM2
De la Rosa, LM2
Greany, TJ2
Zhou, X2
Nanayakkara, S2
Miroshnychenko, A1
Ibrahim, S1
Azab, M1
Roldan, Y1
Diaz Martinez, JP1
Tamilselvan, D1
He, L1
Urquhart, O1
Tampi, M1
Polk, DE1
Moore, PA1
Hersh, EV1
Carrasco-Labra, A1
Brignardello-Petersen, R2
Hegde, V1
Shanmugasundaram, S1
Shaikh, S1
Kulkarni, V1
Suresh, N1
Setzer, FC2
Nagendrababu, V4
Yılmaz, E1
Çağırır Dindaroğlu, F1
Gülnahar, Y1
Alpan, AL1
Gülnahar, E1
Só, GB1
Silva, IA1
Weissheimer, T1
Lenzi, TL1
Só, MVR1
da Rosa, RA1
Elheeny, AAH2
Turky, M2
Karataş, E1
Sümbüllü, M1
Kahraman, ÇY1
Çakmak, FA1
Boëffard, C1
Martin, H1
Amador Del Valle, G1
Enkel, B1
Afkhami, F3
Rostami, G1
Peters, OA1
Kamalian, F1
Sermani, DI1
Saliab, EA1
Hassan, S1
Ahmed, A1
Saqib, W1
Abulhamael, AM1
Habib, SR1
Javed, MQ1
Duncan, HF1
Whitworth, J1
Nekoofar, MH1
Pulikkotil, SJ3
Veettil, SK3
Dummer, PMH2
Zanjir, M1
Lighvan, NL1
Yarascavitch, C1
Beyene, J1
Shah, PS1
Azarpazhooh, A1
Larocca de Geus, J1
Nogueira da Costa, JK1
Wambier, LM1
Maran, BM1
Loguercio, AD1
Reis, A1
Aksoy, F2
Ege, B2
Kumar, U2
Singh, S2
Singh, SP1
Gauba, K1
Nivedha, V1
Sherwood, IA1
Ramaprabha, B1
Bhargavi, PV1
Gao, X1
Meng, K1
Arslan, H2
Doğanay Yıldız, E1
Topçuoğlu, HS3
Tepecik, E1
Taş, G1
Jouhar, R1
Ahmed, MA1
Ghani, B1
Yang, F1
Gao, Y1
Zhang, L1
Zheng, B1
Wang, L1
Sun, H1
Huang, D1
Jadhav, GR1
Mittal, P1
Singla, M10
Gupta, A1
Hasija, M1
Meena, B1
Faghihian, H1
Faghihian, R1
MacDonald, E1
Beck, M16
Kaushik, M1
Mehra, N1
Sharma, R2
Moturi, K1
Podugu, UK1
George, A1
Al-Moraissi, EA1
Al-Selwi, AM1
Al-Zendani, EA1
Stuepp, RT1
Cabral Fenandes, LG1
Melo, G1
Modolo, F1
Ferrari, HJ1
Kumar, M1
Singla, R1
Gill, GS1
Kalra, T1
Jain, N1
Karamifar, K1
Shirali, D1
Saghiri, MA1
Zargar, N1
Shooshtari, E1
Pourmusavi, L1
Akbarzadeh Baghban, A1
Ashraf, H2
Parhizkar, A1
Akpınar, B1
Muhammad, ZA1
Abdullah, RM1
Majid, OW1
Tosun, S1
Pirmoazen, S1
Ardestani, A1
Fard, MJK1
Dias-Junior, LCL1
Bezerra, AP1
Schuldt, DPV1
Kuntze, MM1
de Luca Canto, G1
da Fonseca Roberti Garcia, L1
da Silveira Teixeira, C1
Bortoluzzi, EA1
Miglani, S7
Kohli, S6
Sharma, V2
Bhasin, SS1
Martínez Martínez, A1
Lujan Pardo, MD1
Harris Ricardo, J1
Peters, MC3
Botero, TM3
Shapiro, MR1
McDonald, NJ2
Gardner, RJ2
Vieira, WA1
Paranhos, LR1
Cericato, GO1
Franco, A1
Ribeiro, MAG1
Koteeswaran, V1
Ballal, S1
Natanasabapathy, V2
Kowsky, D1
Suresh, A1
Bhatia, S1
Topçuoğlu, G1
Demirbuga, S1
Dianat, O3
Mozayeni, MA1
Layeghnejad, MK1
Shojaeian, S1
Mousavi, SA1
Sadaghiani, L1
Shahnaseri, S1
Zandian, A1
Farnell, DJJ1
Vianna, ME1
Satish, SV2
Shetty, KP2
Kilaru, K1
Bhargavi, P1
Reddy, ES1
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Su, N2
Wang, H2
Zhang, S1
Liao, S1
Yang, S1
Huang, Y1
Fullmer, S1
Monteiro, MR1
Groppo, FC1
Haiter-Neto, F1
Volpato, MC1
Almeida, JF1
Rogers, BS1
Ahmad, ZH1
Ravikumar, H1
Karale, R1
Preethanath, RS1
Sukumaran, A1
Baghaei, B1
Noormohammadi, H1
Click, V1
Kilaru, KR1
Sardar, P1
Luke, AM1
Schellenberg, J1
Mohajeri, L1
Salehi, F1
Mehrvarzfar, P1
Arfaee, H1
Bohluli, B1
Hamedy, R1
Kung, J1
McDonagh, M1
Sedgley, CM1
Yadav, M1
Grewal, MS1
Grewal, S1
Deshwal, P1
Subbiya, A1
Vivekanandhan, P1
Prakash, V1
Geethapriya, N1
Zain, M1
Rehman Khattak, SU1
Sikandar, H1
Shah, SA1
Li, C1
Shen, J1
Liu, W1
Kou, L1
Elzaki, WM1
Abubakr, NH1
Ziada, HM1
Ibrahim, YE1
Shadmehr, E1
Aminozarbian, MG1
Akhavan, A1
Mahdavian, P1
Davoudi, A1
Visconti, RP1
Tortamano, IP3
Buscariolo, IA2
Lin, S1
Wigler, R1
Huber, R1
Kaufman, AY1
Bultema, K1
Balasubramanian, SK1
Srinivasan, N1
Kavitha, M1
Loganathan, CS1
Padmini, G1
Siviero, M1
Costa, CG1
Armonia, PL1
Jain, A1
Kabi, D2
Maniglia-Ferreira, C1
Almeida-Gomes, F1
Carvalho-Sousa, B1
Barbosa, AV1
Lins, CC1
Souza, FD1
Santos, RA1
Oleson, M1
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Rizvi, A1
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Subbarao, CV1
Gutmann, JL1
Ansari, I1
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Veniashok, B1
Senthilkumar, AD1
Indira, R1
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Kaviani, N1
Ebtehaj, I1
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Kanaa, MD2
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Zarei, M1
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Sharifi, E1
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Yang, D1
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Clinical Trials (30)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Efficiency of Intraligamentary + Buccal Infiltration Anesthesia and Inferior Alveolar Nerve Block + Buccal Infiltration Anesthesia in Symptomatic Mandibular Molars With Irreversible Pulpitis[NCT05839093]210 participants (Actual)Interventional2021-12-21Completed
Evaluation of the Effect of the Photobiomodulation on the Efficacy of Anesthesia of Maxillary Permanent Molar Teeth With MIH[NCT05344014]70 participants (Actual)Interventional2022-01-11Completed
Articaine Versus Lidocaine Supplemental Infiltration Efficacy in Irreversible Pulpitis Mandibular Molars After Failed Inferior Alveolar Nerve Block[NCT01496846]Phase 4201 participants (Actual)Interventional2011-09-30Completed
Efficacy of Two Dental Local Anesthetics on the Oral Health-Related Quality of Life After Endodontic Treatment in the Symptomatic Mandibular Molars: A Double Blind Randomized Controlled Trial[NCT04787731]Phase 4100 participants (Anticipated)Interventional2019-07-29Suspended (stopped due to COVID-19 and Personnel changes)
Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia: Non-inferiority Trial[NCT04166890]Phase 4179 participants (Actual)Interventional2018-09-04Completed
Anaesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine for Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis in Mandibular Molars: A Randomized Clinical Trial[NCT04822415]330 participants (Actual)Interventional2014-12-31Completed
The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded C[NCT04804761]20 participants (Anticipated)Interventional2023-01-01Recruiting
Buffered vs Unbuffered Local Anesthesia Using Lidocaine, Carbocaine, and Articaine in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis[NCT06047366]Phase 460 participants (Anticipated)Interventional2023-12-05Recruiting
Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis: A Controlled, Randomized Double-blind Study[NCT05227300]Phase 440 participants (Anticipated)Interventional2022-02-14Recruiting
Effect of Preoperative Oral Tramadol on the Anaesthetic Efficacy of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind, Controlled Study[NCT04961268]250 participants (Actual)Interventional2020-06-01Completed
Anesthetic Efficacy of 4% Articaine (Mandibular Infiltration) and 2% Lidocaine (Alveolar Nerve Block), Associated With 1:100.000 Epinephrine, in Lower Molars With Irreversible Pulpits[NCT01912755]Phase 450 participants (Actual)Interventional2010-02-28Completed
Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial[NCT03174860]Phase 2/Phase 370 participants (Actual)Interventional2016-10-31Completed
Anesthetic Efficacy of 1.8 ml Compared to 3.6 ml of Articaine Buccal Infiltration in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial[NCT06119139]70 participants (Anticipated)Interventional2023-12-31Not yet recruiting
Comparative Evaluation of Preoperative Methylprednisolone or Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis[NCT04157036]Phase 33 participants (Actual)Interventional2020-02-01Terminated (stopped due to COVID halted recruitment for 2 years. A majority of patients eligible for the study had already taken preoperative analgesics, which disqualified them for the study.)
Effectiveness of Oral Premedication on the Success Rate of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: A Prospective, Double-blind, Randomized Controlled Trial[NCT05097768]250 participants (Actual)Interventional2021-08-15Completed
Efficacy of Pain Control Following Root Canal Treatment Using Paracetamol Alone and in Combination With Three Different Non-Steroidal Anti-Inflammatory Analgesics[NCT02417337]Phase 2170 participants (Actual)Interventional2012-08-31Completed
Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial[NCT03341260]Phase 2/Phase 370 participants (Actual)Interventional2016-12-31Completed
Effect of Ketorolac Premedication on Anesthetic Efficiency of Inferior Alveolar Nerve Block, Pre-Treatment and Post-Endodontic Pain in Teeth With Irreversible Pulpitis: A Randomized Controlled Double Blinded Trial[NCT02940405]38 participants (Anticipated)Interventional2017-01-31Not yet recruiting
Effect of Volume Increase Compared to Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Block Success in Cases With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial[NCT05238727]75 participants (Anticipated)Interventional2022-03-31Not yet recruiting
Effect of Pre-operative Diclofenac Potassium on the Anesthetic Efficacy of Inferior Alveolar Nerve Block in Cases With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial[NCT03163420]Phase 2/Phase 368 participants (Anticipated)Interventional2016-07-31Active, not recruiting
Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block on Patients With Symptomatic Irreversible Pulpitis: a Double Blinded, Randomized Controlled Trial.[NCT05488925]Phase 4120 participants (Actual)Interventional2021-06-21Completed
Evaluation the Effect of Using Preoperative Ibuprofen Versus Low Level Laser Therapy on Inferior Alveolar Nerve Block[NCT05479175]76 participants (Anticipated)Interventional2022-05-01Active, not recruiting
Assessment of Efficacy and Safety of Primary Maxillary Second Molars Anesthesia Using Nasal Spray in Children[NCT03140787]68 participants (Actual)Interventional2016-05-15Completed
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment[NCT05338671]Phase 440 participants (Anticipated)Interventional2021-09-29Active, not recruiting
The Incidence of Postoperative Pain After Using Different Types of Sealers (A Randomized Clinical Trial)[NCT05841290]40 participants (Anticipated)Interventional2023-05-31Not yet recruiting
Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573]Phase 131 participants (Actual)Interventional2004-04-30Completed
Anesthetic Efficacy of 4% Buffered Lidocaine in Emergency Patients With Facial Swelling.[NCT01981772]88 participants (Actual)Interventional2013-03-31Completed
Effect of Preoperative Acetaminophen-Codeine-Caffeine Combination on Inferior Alveolar Nerve Block Success in Patients With Symptomatic Irreversible Pulpitis: Randomized Double-blind Controlled Trial[NCT04202406]69 participants (Actual)Interventional2021-01-09Completed
Efficacy of the Combination Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: a Randomized Clinical Trial.[NCT02110966]Phase 456 participants (Actual)Interventional2014-04-30Completed
A Prospective, Randomized, Double-blind Study of the Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Inferior Alveolar Nerve Blocks.[NCT01574807]Phase 4100 participants (Actual)Interventional2012-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Anesthetic Success Rate of an IANB With Articaine

Success rate of an IANB with articaine using a conventional IANB technique (NCT01496846)
Timeframe: 15 min after injection

InterventionParticipants (Count of Participants)
IANB Articaine - 1st Molar27
IANB Articaine - 2nd Molar23

Anesthetic Success Rate of Supplemental Infiltration Injection

Following an unsuccessful IANB, supplemental infiltration anesthesia with either articaine or lidocaine was given to achieve complete pulpal anesthesia (NCT01496846)
Timeframe: 5 min after injection

InterventionParticipants (Count of Participants)
IANB Articaine and SUP Articaine - 1st Molar22
IANB Articaine and SUP Articaine - 2nd Molar25
IANB Articaine and SUP Lidocaine - 1st Molar23
IANB Articaine and SUP Lidocaine - 2nd Molar12

Pain Measurement as Assessed on a Heft-Parker 170 mm Visual Analog Scale

"Patients will rate pain on a Heft-Parker visual analog scale during needle insertion, placement, and solution deposition phases of the anesthetic injection(s). Patients will also rate pain during the incision and dissection phases of the incision and drainage procedure. The number of millimeters along the scale are reported. No pain corresponded to 0 mm. Mild pain was defined as greater than 0 mm and less than or equal to 54 mm. Mild pain included the descriptors of faint, weak, and mild pain. Moderate pain was defined as greater than 54 mm and less than 114 mm and included the descriptor moderate. Severe pain was defined as equal to or greater than 114 mm up to and including 170 mm. Severe pain included the descriptors of strong, intense, and maximum possible." (NCT01981772)
Timeframe: during incision/drainage on Day 0

Interventionunits on a scale (Mean)
Buffered Lidocaine69.3
Nonbuffered Lidocaine59.2

Postoperative Satisfaction on a 100 mm Visual Analog Scale

"Patients will rate their level of satisfaction with the incision and drainage procedure using a visual analog scale. The scale ranges from not satisfied, to somewhat satisfied, to moderately satisfied, to completely satisfied. Not satisfied corresponded to 0 mm. Somewhat satisfied was defined as greater than 0 mm and less than or equal to 33 mm. Moderately satisfied was defined as greater than 33 mm and less than 66 mm. Completely satisfied was defined as equal to or greater than 66 mm. Measurements along the scale were collected and analyzed by randomization test." (NCT01981772)
Timeframe: immediately post-procedure on Day 0

Interventionunits on a scale (Mean)
Buffered Lidocaine92.7
Nonbuffered Lidocaine89.5

Number of Participants Achieving Pulpal Anesthesia Success.

An electric pulp tester will be used to test the lower jaw teeth (molars, premolars, and incisors) for anesthesia (numbness) in 4-minute time cycles for 60 minutes. Measurements of less than 80 on the EPT is considered not numb (anesthesia failure). Readings of 80 equate to anesthetic success. (NCT01574807)
Timeframe: 60 minutes per injection sequence.

InterventionParticipants (Count of Participants)
Mepivacaine + Lidocaine44
Lidocaine + Lidocaine40

Reviews

18 reviews available for lidocaine and Inflammation, Endodontic

ArticleYear
Can buccal infiltration of articaine replace traditional inferior alveolar nerve block for the treatment of mandibular molars in pediatric patients?: A systematic review and meta-analysis.
    Medicina oral, patologia oral y cirugia bucal, 2021, Nov-01, Volume: 26, Issue:6

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Child; Double-Blind Method; Humans; Lidocaine; M

2021
Present status and future directions-Mechanisms and management of local anaesthetic failures.
    International endodontic journal, 2022, Volume: 55 Suppl 4

    Topics: Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents; Humans; Lidocaine; Mandibular Nerv

2022
Anaesthetic efficacy of incorporating different additives into lidocaine for the inferior alveolar nerve block: A systematic review with meta-analysis and trial sequential analysis.
    International endodontic journal, 2022, Volume: 55, Issue:7

    Topics: Anesthesia, Dental; Anesthetics; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibu

2022
EFFICACY OF 4% ARTICAINE BUCCAL INFILTRATION VERSUS INFERIOR ALVEOLAR NERVE BLOCK FOR MANDIBULAR MOLARS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS.
    The journal of evidence-based dental practice, 2022, Volume: 22, Issue:2

    Topics: Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Molar; Ner

2022
BUCCAL INFILTRATION WITH 4% ARTICAINE MAY BE AN ALTERNATIVE OPTION TO INFERIOR ALVEOLAR NERVE BLOCK WITH 2% LIDOCAINE FOR PULP THERAPY IN PRIMARY MANDIBULAR MOLARS.
    The journal of evidence-based dental practice, 2022, Volume: 22, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2022
BUCCAL INFILTRATION WITH 4% ARTICAINE MAY BE AN ALTERNATIVE OPTION TO INFERIOR ALVEOLAR NERVE BLOCK WITH 2% LIDOCAINE FOR PULP THERAPY IN PRIMARY MANDIBULAR MOLARS.
    The journal of evidence-based dental practice, 2022, Volume: 22, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2022
BUCCAL INFILTRATION WITH 4% ARTICAINE MAY BE AN ALTERNATIVE OPTION TO INFERIOR ALVEOLAR NERVE BLOCK WITH 2% LIDOCAINE FOR PULP THERAPY IN PRIMARY MANDIBULAR MOLARS.
    The journal of evidence-based dental practice, 2022, Volume: 22, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2022
BUCCAL INFILTRATION WITH 4% ARTICAINE MAY BE AN ALTERNATIVE OPTION TO INFERIOR ALVEOLAR NERVE BLOCK WITH 2% LIDOCAINE FOR PULP THERAPY IN PRIMARY MANDIBULAR MOLARS.
    The journal of evidence-based dental practice, 2022, Volume: 22, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2022
Injectable and topical local anesthetics for acute dental pain: 2 systematic reviews.
    Journal of the American Dental Association (1939), 2023, Volume: 154, Issue:1

    Topics: Acute Pain; Anesthesia, Local; Anesthetics, Local; Benzocaine; Bupivacaine; Epinephrine; Humans; Lid

2023
Do NSAIDs used prior to standard inferior alveolar nerve blocks improve the analgesia of mandibular molars with irreversible pulpitis? An umbrella review.
    Clinical oral investigations, 2023, Volume: 27, Issue:5

    Topics: Analgesia; Anesthesia, Dental; Anesthetics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroi

2023
Is articaine more effective than lidocaine in patients with irreversible pulpitis? An umbrella review.
    International endodontic journal, 2020, Volume: 53, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Humans; Lidocaine; Pulpitis

2020
Efficacy and Safety of Pulpal Anesthesia Strategies during Endodontic Treatment of Permanent Mandibular Molars with Symptomatic Irreversible Pulpitis: A Systematic Review and Network Meta-analysis.
    Journal of endodontics, 2019, Volume: 45, Issue:12

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2019
Different anesthetics on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis: A network systematic review and meta-analysis.
    Journal of the American Dental Association (1939), 2020, Volume: 151, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Bayes Theorem; Brazil; Double-Blind Method; Humans; Lidocain

2020
Local anaesthesia for surgical extraction of mandibular third molars: a systematic review and network meta-analysis.
    Clinical oral investigations, 2020, Volume: 24, Issue:11

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bayes Theorem; Carticaine; Double-Blind M

2020
Comparing the anaesthetic efficacy of 1.8 mL and 3.6 mL of anaesthetic solution for inferior alveolar nerve blocks for teeth with irreversible pulpitis: a systematic review and meta-analysis with trial sequential analysis.
    International endodontic journal, 2021, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidoca

2021
Effectiveness of different anesthetic methods for mandibular posterior teeth with symptomatic irreversible pulpitis: a systematic review and meta-analysis.
    Clinical oral investigations, 2021, Volume: 25, Issue:12

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Pu

2021
Is mepivacaine as effective as lidocaine during inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis? A systematic review and meta-analysis.
    International endodontic journal, 2018, Volume: 51, Issue:10

    Topics: Anesthesia, Dental; Anesthetics, Local; Humans; Lidocaine; Mepivacaine; Nerve Block; Pain Management

2018
Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a systematic review and network meta-analysis of randomized clinical trials.
    International endodontic journal, 2019, Volume: 52, Issue:6

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Ne

2019
Efficacy and safety of bupivacaine versus lidocaine in dental treatments: a meta-analysis of randomised controlled trials.
    International dental journal, 2014, Volume: 64, Issue:1

    Topics: Analgesics; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Dental Pulp; Epi

2014
Does Articaine Provide an Advantage over Lidocaine in Patients with Symptomatic Irreversible Pulpitis? A Systematic Review and Meta-analysis.
    Journal of endodontics, 2015, Volume: 41, Issue:11

    Topics: Anesthesia, Local; Anesthetics, Local; Carticaine; Humans; Lidocaine; Preoperative Care; Pulpitis; R

2015
Efficacy and safety of articaine versus lidocaine for irreversible pulpitis treatment: A systematic review and meta-analysis of randomised controlled trials.
    Australian endodontic journal : the journal of the Australian Society of Endodontology Inc, 2016, Volume: 42, Issue:1

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Humans; Lidocaine; Pulpitis; Randomized Controll

2016

Trials

94 trials available for lidocaine and Inflammation, Endodontic

ArticleYear
Effect of precooling injection site and cold anesthetic administration on injection pain, onset, and anesthetic efficacy in maxillary molars with symptomatic irreversible pulpitis: a randomized controlled trial.
    Clinical oral investigations, 2022, Volume: 26, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Mo

2022
Articaine Infiltration Versus Lidocaine Inferior Alveolar Nerve Block for Anesthetizing Primary Mandibular Molars: A Randomized, Controlled, Double-Blind Pilot Study.
    Pediatric dentistry, 2021, 09-15, Volume: 43, Issue:5

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Child; Child, Preschool; Double-Blind Method; Hu

2021
Efficacy of four local anaesthesia protocols for mandibular first molars with symptomatic irreversible pulpitis: A randomized clinical trial.
    International endodontic journal, 2022, Volume: 55, Issue:3

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Humans; Lidocaine; Mandibular Nerve; Mola

2022
Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial.
    Clinical oral investigations, 2022, Volume: 26, Issue:7

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Lidocai

2022
Application of a Remotely Controlled Artificial Intelligence Analgesic Pump Device in Painless Treatment of Children.
    Contrast media & molecular imaging, 2022, Volume: 2022

    Topics: Analgesics; Anesthetics, Local; Artificial Intelligence; Carticaine; Child; Double-Blind Method; Epi

2022
Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
    Australian endodontic journal : the journal of the Australian Society of Endodontology Inc, 2023, Volume: 49, Issue:1

    Topics: Acetaminophen; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Ibuprofen; Lidoc

2023
Inferior alveolar nerve block success of 2% mepivacaine versus 4% articaine in patients with symptomatic irreversible pulpitis in mandibular molars: A randomized double-blind single-centre clinical trial.
    International endodontic journal, 2022, Volume: 55, Issue:11

    Topics: Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Mepivacain

2022
Evaluation of pulpal anesthesia and injection pain using IANB with pre-heated, buffered and conventional 2% lignocaine in teeth with symptomatic irreversible pulpitis-a randomized clinical study.
    PeerJ, 2022, Volume: 10

    Topics: Adult; Anesthetics, Local; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Pain; Pulpitis

2022
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
    Quintessence international (Berlin, Germany : 1985), 2023, Feb-10, Volume: 54, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor

2023
Anaesthetic efficacy and influence on cardiovascular parameters change of intraosseous computerised anaesthesia versus inferior alveolar nerve block anaesthesia in acute irreversible pulpitis of mandibular molars: study protocol for a prospective randomis
    Trials, 2022, Dec-05, Volume: 23, Issue:1

    Topics: Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Prospecti

2022
Anaesthetic efficacy and influence on cardiovascular parameters change of intraosseous computerised anaesthesia versus inferior alveolar nerve block anaesthesia in acute irreversible pulpitis of mandibular molars: study protocol for a prospective randomis
    Trials, 2022, Dec-05, Volume: 23, Issue:1

    Topics: Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Prospecti

2022
Anaesthetic efficacy and influence on cardiovascular parameters change of intraosseous computerised anaesthesia versus inferior alveolar nerve block anaesthesia in acute irreversible pulpitis of mandibular molars: study protocol for a prospective randomis
    Trials, 2022, Dec-05, Volume: 23, Issue:1

    Topics: Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Prospecti

2022
Anaesthetic efficacy and influence on cardiovascular parameters change of intraosseous computerised anaesthesia versus inferior alveolar nerve block anaesthesia in acute irreversible pulpitis of mandibular molars: study protocol for a prospective randomis
    Trials, 2022, Dec-05, Volume: 23, Issue:1

    Topics: Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Prospecti

2022
Effect of Preoperative Oral Steroids in Comparison to Anti-inflammatory on Anesthetic Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis-A Double-blinded Randomized Clinical Trial.
    Journal of endodontics, 2023, Volume: 49, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents; Dexamethasone; Double-Blind Method

2023
Comparison of the effectiveness of intraligamentary anesthesia and inferior alveolar nerve block on mandibular molar teeth in pediatric patients: a randomized controlled clinical study.
    Clinical oral investigations, 2023, Volume: 27, Issue:6

    Topics: Anesthesia, Dental; Anesthetics, Local; Child; Double-Blind Method; Facial Pain; Humans; Lidocaine;

2023
Articaine versus lidocaine inferior alveolar nerve block in posterior mandible implant surgeries: a randomized controlled trial.
    Medicina oral, patologia oral y cirugia bucal, 2023, Mar-01, Volume: 28, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Hypesthesia; Lidoca

2023
Inferior Alveolar Nerve Block Plus Cryotherapy Anesthesia Success in Pulpectomy Of Primary Molars with Irreversible Pulpitis: a Randomized Clinical Trial.
    Pediatric dentistry, 2023, Mar-15, Volume: 45, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Child; Cryotherapy; Double-Blind Method; Humans;

2023
Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial.
    International endodontic journal, 2023, Volume: 56, Issue:8

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Ne

2023
Pulpal anesthesia of maxillary first molars using 4% articaine infiltration in patients with symptomatic irreversible pulpitis: a randomized controlled clinical trial.
    Clinical oral investigations, 2023, Volume: 27, Issue:7

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Epinephrine; Humans; Lidoca

2023
Cryotherapy and pain intensity during endodontic treatment of mandibular first permanent molars with symptomatic irreversible pulpitis: A randomized controlled trial.
    Clinical oral investigations, 2023, Volume: 27, Issue:8

    Topics: Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cryotherapy; Double-Blind Method; Humans;

2023
Comparison of Efficacy of Lidocaine and Articaine as Inferior Alveolar Nerve Blocking Agents in Patients with Symptomatic Irreversible Pulpitis: Randomized Controlled Trial.
    Medicina (Kaunas, Lithuania), 2023, Oct-16, Volume: 59, Issue:10

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2023
Is Bilateral Mental Incisive Nerve Block Better than Unilateral Mental Incisive Nerve Block during the Endodontic Management of Mandibular Incisors with Symptomatic Irreversible Pulpitis? A Prospective Single-blind Randomized Clinical Trial.
    Journal of endodontics, 2020, Volume: 46, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Incisor; Lidocaine; Mandibular

2020
Comparison of articaine, lidocaine and mepivacaine for buccal infiltration after inferior alveolar nerve block in mandibular posterior teeth with irreversible pulpitis.
    British dental journal, 2020, Volume: 228, Issue:8

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2020
Effect of calcium hydroxide mixed with lidocaine hydrochloride on postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis: a preliminary randomized controlled prospective clinical trial.
    Clinical oral investigations, 2021, Volume: 25, Issue:1

    Topics: Calcium Hydroxide; Double-Blind Method; Humans; Lidocaine; Pain, Postoperative; Periapical Periodont

2021
Determination of Anesthetic Efficacy of Lidocaine Versus Bupivacaine in Single Visit Root Canal Treatment.
    European endodontic journal, 2020, Volume: 5, Issue:2

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Female; Follow-Up Studies; Humans; Inject

2020
Evaluation of aromatherapy on success rate of inferior alveolar nerve block in teeth with irreversible pulpitis: a prospective randomized clinical trial.
    Quintessence international (Berlin, Germany : 1985), 2020, Volume: 51, Issue:10

    Topics: Anesthesia, Dental; Anesthetics, Local; Aromatherapy; Double-Blind Method; Humans; Lidocaine; Mandib

2020
Preoperative Intraligamentary Injection of Dexamethasone Can Improve the Anesthetic Success Rate of 2% Lidocaine during the Endodontic Management of Mandibular Molars with Symptomatic Irreversible Pulpitis.
    Journal of endodontics, 2021, Volume: 47, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Lidocaine; Mandi

2021
Anesthetic Efficacy of Lidocaine/Ketorolac in Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial.
    European endodontic journal, 2020, Volume: 5, Issue:3

    Topics: Adult; Anesthetics, Local; Humans; Ketorolac; Lidocaine; Mandibular Nerve; Nerve Block; Prospective

2020
Anesthetic Success Using Nitrous Oxide and a Combination of Lidocaine/Clonidine for the Inferior Alveolar Nerve Block and the Effects on Blood Pressure and Pulse in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind S
    Journal of endodontics, 2021, Volume: 47, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Blood Pressure; Clonidine; Double-Blind Method; Humans; Lido

2021
Comparing the Efficacy of Twin Mix and Lidocaine for Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis.
    Anesthesia progress, 2020, 12-01, Volume: 67, Issue:4

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Ne

2020
Do length and gauge of dental needle affect success in performing an inferior alveolar nerve block during extraction of adult mandibular molars? A prospective, randomized observer-blind, clinical trial.
    Clinical oral investigations, 2021, Volume: 25, Issue:8

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; M

2021
Anesthetic Efficacy of an Alternative Inferior Alveolar Nerve Block Technique Using an Extra-Short Needle: A Double-Blind Randomized Non-Inferiority Trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2021, Volume: 79, Issue:5

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Ne

2021
Evaluating Combined Effect of Oral Premedication with Ibuprofen and Dexamethasone on Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial.
    Journal of endodontics, 2021, Volume: 47, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Dexamethason

2021
Retromolar canal infiltration as a supplement to the inferior alveolar nerve block injection: an uncontrolled clinical trial.
    Clinical oral investigations, 2021, Volume: 25, Issue:9

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Ne

2021
Anaesthetic Efficacy of 4% Articaine in Comparison with 2% Lidocaine as Intraligamentary Injections after an Ineffective Inferior Alveolar Nerve Block in Mandibular Molars with Irreversible Pulpitis: A Prospective Randomised Triple-Blind Clinical Trial.
    Pain research & management, 2021, Volume: 2021

    Topics: Adult; Anesthetics, Local; Carticaine; Female; Humans; Injections; Lidocaine; Ligaments; Male; Mandi

2021
The effect of low-level laser therapy on the success rate of inferior alveolar nerve blocks in mandibular molars with symptomatic irreversible pulpitis: A randomized clinical trial.
    International endodontic journal, 2021, Volume: 54, Issue:10

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Low-Level Light Ther

2021
Articaine improves anesthetic achievement for exodontia performed by undergraduate dental students: A clinical comparative study.
    Journal of dental education, 2021, Volume: 85, Issue:11

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2021
The effect of pre-operative submucosal administration of dexamethasone, tramadol, articaine on the success rate of inferior alveolar nerve block on mandibular molars with symptomatic irreversible pulpitis: A randomized, double-blind placebo-controlled cli
    International endodontic journal, 2021, Volume: 54, Issue:11

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Dexamethasone; Double-Blind Method; Humans; Lido

2021
Comparative evaluation of anesthetic efficacy of inferior alveolar nerve block and inferior alveolar nerve block plus buccal or lingual infiltration using articaine in mandibular molars with irreversible pulpitis: a preliminary prospective randomized sin
    Quintessence international (Berlin, Germany : 1985), 2021, Sep-09, Volume: 52, Issue:9

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibul

2021
Does the volume of supplemental intraligamentary injections affect the anaesthetic success rate after a failed primary inferior alveolar nerve block? A randomized-double blind clinical trial.
    International endodontic journal, 2018, Volume: 51, Issue:1

    Topics: Adult; Anesthetics, Local; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; In

2018
Efficacy of Articaine versus Lidocaine in Supplemental Infiltration for Mandibular First versus Second Molars with Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial.
    Journal of endodontics, 2018, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Lido

2018
Efficacy of Articaine versus Lidocaine in Supplemental Infiltration for Mandibular First versus Second Molars with Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial.
    Journal of endodontics, 2018, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Lido

2018
Efficacy of Articaine versus Lidocaine in Supplemental Infiltration for Mandibular First versus Second Molars with Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial.
    Journal of endodontics, 2018, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Lido

2018
Efficacy of Articaine versus Lidocaine in Supplemental Infiltration for Mandibular First versus Second Molars with Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial.
    Journal of endodontics, 2018, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Lido

2018
Efficacy of Articaine Versus Lidocaine Administered as Supplementary Intraligamentary Injection after a Failed Inferior Alveolar Nerve Block: A Randomized Double-blind Study.
    Journal of endodontics, 2019, Volume: 45, Issue:1

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Inje

2019
Efficacy of Endo-Ice followed by intrapulpal ice application as an adjunct to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis-a randomized controlled trial.
    Clinical oral investigations, 2019, Volume: 23, Issue:9

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Ice;

2019
The Effect of Cryotherapy Application on the Success Rate of Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis.
    Journal of endodontics, 2019, Volume: 45, Issue:8

    Topics: Anesthesia, Dental; Anesthetics, Local; Cryotherapy; Double-Blind Method; Humans; Lidocaine; Mandibu

2019
The efficacy of supplemental intraseptal and buccal infiltration anesthesia in mandibular molars of patients with symptomatic irreversible pulpitis.
    Clinical oral investigations, 2020, Volume: 24, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Double-Blind Method; F

2020
Effect of magnesium sulphate added to lidocaine on inferior alveolar nerve block success in patients with symptoms of irreversible pulpitis: a prospective, randomized clinical trial.
    International endodontic journal, 2020, Volume: 53, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Magnesium Sulfate; M

2020
Comparison of the anaesthetic efficacy of epinephrine concentrations (1 : 80 000 and 1 : 200 000) in 2% lidocaine for inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a randomized, double-blind clinical trial.
    International endodontic journal, 2014, Volume: 47, Issue:4

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Epinephrine; Female; Humans; Lidocaine; Male; Mandib

2014
Comparative evaluation of the efficacy of 2% lidocaine containing 1:200,000 epinephrine with and without hyaluronidase (75 IU) in patients with irreversible pulpitis.
    Journal of endodontics, 2013, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Antigens, Neoplasm; Dental Pulp; Double-B

2013
Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study.
    Journal of endodontics, 2014, Volume: 40, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Local;

2014
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
4% articaine buccal infiltration versus 2% lidocaine inferior alveolar nerve block for emergency root canal treatment in mandibular molars with irreversible pulpits: a randomized clinical study.
    International endodontic journal, 2015, Volume: 48, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Emergencies; Female; Humans; Lidocaine; M

2015
Efficacy of articaine versus lidocaine as a supplemental buccal infiltration in mandibular molars with irreversible pulpitis: a prospective, randomized, double-blind study.
    Journal of endodontics, 2014, Volume: 40, Issue:6

    Topics: Administration, Buccal; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Meth

2014
Efficacy of articaine versus lidocaine as a supplemental buccal infiltration in mandibular molars with irreversible pulpitis: a prospective, randomized, double-blind study.
    Journal of endodontics, 2014, Volume: 40, Issue:6

    Topics: Administration, Buccal; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Meth

2014
Efficacy of articaine versus lidocaine as a supplemental buccal infiltration in mandibular molars with irreversible pulpitis: a prospective, randomized, double-blind study.
    Journal of endodontics, 2014, Volume: 40, Issue:6

    Topics: Administration, Buccal; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Meth

2014
Efficacy of articaine versus lidocaine as a supplemental buccal infiltration in mandibular molars with irreversible pulpitis: a prospective, randomized, double-blind study.
    Journal of endodontics, 2014, Volume: 40, Issue:6

    Topics: Administration, Buccal; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Meth

2014
Effect of sodium bicarbonate-buffered lidocaine on the success of inferior alveolar nerve block for teeth with symptomatic irreversible pulpitis: a prospective, randomized double-blind study.
    Journal of endodontics, 2015, Volume: 41, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Combined; Anesthet

2015
Evaluation of the Gow-Gates and Vazirani-Akinosi techniques in patients with symptomatic irreversible pulpitis: a prospective randomized study.
    Journal of endodontics, 2015, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans;

2015
Comparison of anesthetic efficacy between lidocaine with and without magnesium sulfate USP 50% for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis.
    Journal of endodontics, 2015, Volume: 41, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Magne

2015
Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study.
    Journal of endodontics, 2015, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Alveolar Process; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidoca

2015
Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study.
    Journal of endodontics, 2015, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Alveolar Process; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidoca

2015
Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study.
    Journal of endodontics, 2015, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Alveolar Process; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidoca

2015
Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study.
    Journal of endodontics, 2015, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Alveolar Process; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidoca

2015
Anesthetic efficacy of meperidine in teeth with symptomatic irreversible pulpitis.
    Anesthesia progress, 2015,Spring, Volume: 62, Issue:1

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Local; Dental Pulp;

2015
Comparison of Preoperative Oral Ketorolac on Anesthetic Efficacy of Inferior Alveolar Nerve Block and Buccal and Lingual Infiltration with Articaine and Lidocaine in Patients with Irreversible Pulpitis: A Prospective, Randomized, Controlled, Double-blind
    Journal of endodontics, 2015, Volume: 41, Issue:11

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carticaine; Double-Blind Method;

2015
Comparison of Preoperative Oral Ketorolac on Anesthetic Efficacy of Inferior Alveolar Nerve Block and Buccal and Lingual Infiltration with Articaine and Lidocaine in Patients with Irreversible Pulpitis: A Prospective, Randomized, Controlled, Double-blind
    Journal of endodontics, 2015, Volume: 41, Issue:11

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carticaine; Double-Blind Method;

2015
Comparison of Preoperative Oral Ketorolac on Anesthetic Efficacy of Inferior Alveolar Nerve Block and Buccal and Lingual Infiltration with Articaine and Lidocaine in Patients with Irreversible Pulpitis: A Prospective, Randomized, Controlled, Double-blind
    Journal of endodontics, 2015, Volume: 41, Issue:11

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carticaine; Double-Blind Method;

2015
Comparison of Preoperative Oral Ketorolac on Anesthetic Efficacy of Inferior Alveolar Nerve Block and Buccal and Lingual Infiltration with Articaine and Lidocaine in Patients with Irreversible Pulpitis: A Prospective, Randomized, Controlled, Double-blind
    Journal of endodontics, 2015, Volume: 41, Issue:11

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carticaine; Double-Blind Method;

2015
Effect of Preoperative Pain on Inferior Alveolar Nerve Block.
    Anesthesia progress, 2015,Winter, Volume: 62, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Epinephrine; Female; Humans; Lid

2015
Comparison of Anaesthetic Efficacy of 4% Articaine Primary Buccal Infiltration Versus 2% Lidocaine Inferior Alveolar Nerve Block in Symptomatic Mandibular First Molar Teeth.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016, Volume: 26, Issue:1

    Topics: Administration, Buccal; Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Femal

2016
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Comparative Evaluation of Mental Incisal Nerve Block, Inferior Alveolar Nerve Block, and Their Combination on the Anesthetic Success Rate in Symptomatic Mandibular Premolars: A Randomized Double-blind Clinical Trial.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid; Double-Blind Method; Dru

2016
Anaesthetic efficacy of lidocaine/clonidine for inferior alveolar nerve block in patients with irreversible pulpitis.
    International endodontic journal, 2017, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Anesthesia, Dental; Clonidine; Double-Blind Method; Epinephrine; Female; Humans;

2017
Comparison of the Anesthetic Efficacy of Mepivacaine and Lidocaine in Patients with Irreversible Pulpitis: A Double-blind Randomized Clinical Trial.
    Journal of endodontics, 2016, Volume: 42, Issue:9

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male;

2016
Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial.
    Journal of endodontics, 2016, Volume: 42, Issue:12

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthesia,

2016
Comparison of anesthetic efficacy of 4% articaine and 2% lidocaine for maxillary buccal infiltration in patients with irreversible pulpitis.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2009, Volume: 107, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid; Carticaine;

2009
A comparison of the anesthetic efficacy of articaine and lidocaine in patients with irreversible pulpitis.
    Journal of endodontics, 2009, Volume: 35, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Bicuspid; Carticaine; Dental Pulp Test; Double-Blind

2009
Anesthetic efficacy of supplemental buccal and lingual infiltrations of articaine and lidocaine after an inferior alveolar nerve block in patients with irreversible pulpitis.
    Journal of endodontics, 2009, Volume: 35, Issue:7

    Topics: Administration, Buccal; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine

2009
Clinical evaluation of the use of three anesthetics in endodontics.
    Acta odontologica latinoamericana : AOL, 2009, Volume: 22, Issue:1

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Cost-Benefit Analysis; Dose-Response Relationship, Dr

2009
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square D

2010
Effect of preoperative ibuprofen on the success of the inferior alveolar nerve block in patients with irreversible pulpitis.
    Journal of endodontics, 2010, Volume: 36, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bicuspid; Ch

2010
Efficacy of combining a buccal infiltration with an inferior alveolar nerve block for mandibular molars with irreversible pulpitis.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 109, Issue:3

    Topics: Administration, Buccal; Adult; Analysis of Variance; Anesthesia, Dental; Anesthesia, Local; Anesthet

2010
The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
    Journal of endodontics, 2010, Volume: 36, Issue:9

    Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-S

2010
Comparative evaluation of local infiltration of articaine, articaine plus ketorolac, and dexamethasone on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis.
    Journal of endodontics, 2011, Volume: 37, Issue:4

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cartic

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
The efficacy of pre-operative oral medication of lornoxicam and diclofenac potassium on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a double-blind, randomised controlled clinical trial.
    International endodontic journal, 2011, Volume: 44, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Cyclooxygenase Inhibitors; D

2011
A prospective, randomized, single-blind comparative evaluation of anesthetic efficacy of posterior superior alveolar nerve blocks, buccal infiltrations, and buccal plus palatal infiltrations in patients with irreversible pulpitis.
    Journal of endodontics, 2011, Volume: 37, Issue:11

    Topics: Administration, Buccal; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Female; Hu

2011
Anesthetic efficacy of four percent articaine for pulpal anesthesia by using inferior alveolar nerve block and buccal infiltration techniques in patients with irreversible pulpitis: a prospective randomized double-blind clinical trial.
    Journal of endodontics, 2011, Volume: 37, Issue:12

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Cheek; Dental Pulp; Double-Bl

2011
The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis.
    Journal of oral science, 2011, Volume: 53, Issue:4

    Topics: Adjuvants, Anesthesia; Administration, Oral; Adolescent; Adult; Analgesics; Anesthesia, Dental; Anes

2011
A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:3

    Topics: Administration, Buccal; Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Dent

2012
Comparison of the anaesthetic efficacy of and heart rate changes after periodontal ligament or intraosseous X-Tip injection in mandibular molars: a randomized controlled clinical trial.
    International endodontic journal, 2012, Volume: 45, Issue:10

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Bone and Bones; Female; Heart Rate; Human

2012
Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar.
    Journal of endodontics, 2012, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Dental Pulp; Dental Pulp Test; Double-Blind Meth

2012
Anesthetic efficacy of combinations of 0.5 mol/L mannitol and lidocaine with epinephrine for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:5

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Bicuspid; Dental P

2012
Comparative evaluation of 1.8 mL and 3.6 mL of 2% lidocaine with 1:200,000 epinephrine for inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, randomized single-blind study.
    Journal of endodontics, 2012, Volume: 38, Issue:6

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distribution; Dose-Response Relationship,

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Efficacy of articaine versus lidocaine in block and infiltration anesthesia administered in teeth with irreversible pulpitis: a prospective, randomized, double-blind study.
    Journal of endodontics, 2013, Volume: 39, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Carticaine; Double-Blind Meth

2013
Effect of premedication with ibuprofen and dexamethasone on success rate of inferior alveolar nerve block for teeth with asymptomatic irreversible pulpitis: a randomized clinical trial.
    Journal of endodontics, 2013, Volume: 39, Issue:2

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Asympt

2013
Anaesthetic efficacy of supplemental lingual infiltration of mandibular molars after inferior alveolar nerve block plus buccal infiltration in patients with irreversible pulpitis.
    International endodontic journal, 2013, Volume: 46, Issue:7

    Topics: Administration, Buccal; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine

2013
Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis.
    Journal of endodontics, 2004, Volume: 30, Issue:8

    Topics: Adult; Anesthetics, Local; Carticaine; Double-Blind Method; Epinephrine; Female; Humans; Lidocaine;

2004
Anesthetic effectiveness of the supplemental intraligamentary injection, administered with a computer-controlled local anesthetic delivery system, in patients with irreversible pulpitis.
    Journal of endodontics, 2005, Volume: 31, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Delivery Systems; Female; Humans; Injections; Li

2005
The use of an intra-oral injection of ketorolac in the treatment of irreversible pulpitis.
    International endodontic journal, 2005, Volume: 38, Issue:11

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Epinephrine

2005
Anesthetic efficacy of lidocaine/meperidine for inferior alveolar nerve blocks in patients with irreversible pulpitis.
    Journal of endodontics, 2007, Volume: 33, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Anesthetics, Combined; Anesthetics, Local; Female; Humans; Lidocaine;

2007
Comparison of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:100,000 epinephrine when used as a supplemental anesthetic.
    Journal of endodontics, 2007, Volume: 33, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Carticaine; Double-Blind Metho

2007
Comparison of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:100,000 epinephrine when used as a supplemental anesthetic.
    Journal of endodontics, 2007, Volume: 33, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Carticaine; Double-Blind Metho

2007
Comparison of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:100,000 epinephrine when used as a supplemental anesthetic.
    Journal of endodontics, 2007, Volume: 33, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Carticaine; Double-Blind Metho

2007
Comparison of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:100,000 epinephrine when used as a supplemental anesthetic.
    Journal of endodontics, 2007, Volume: 33, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Carticaine; Double-Blind Metho

2007
Use of the cold test as a measure of pulpal anesthesia during endodontic therapy: a randomized, blinded, placebo-controlled clinical trial.
    Journal of endodontics, 2007, Volume: 33, Issue:4

    Topics: Adult; Age Factors; Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Cold Temperature; Dental Pu

2007
Anesthetic efficacy of the Gow-Gates injection and maxillary infiltration with articaine and lidocaine for irreversible pulpitis.
    Journal of endodontics, 2008, Volume: 34, Issue:6

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Chi-Square Distribution; Doub

2008
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Endodontic anesthesia in mandibular molars: a clinical study.
    Journal of endodontics, 1993, Volume: 19, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Chi-Square Distribution; Chlorofluorocarbons, Methane; Dental

1993
Anesthetic efficacy of the supplemental intraosseous injection for teeth with irreversible pulpitis.
    Journal of endodontics, 1998, Volume: 24, Issue:12

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Evaluation Studies as Topic; Humans; Inje

1998
Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.
    Journal of endodontics, 2000, Volume: 26, Issue:11

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Anti-I

2000

Other Studies

28 other studies available for lidocaine and Inflammation, Endodontic

ArticleYear
Effect of a Combination of Nitrous Oxide and Intraligamentary Injection on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis.
    Journal of endodontics, 2021, Volume: 47, Issue:12

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Ne

2021
A pilot study of local anesthesia training using a mixed-reality haptic fidelity model.
    Journal of dental education, 2023, Volume: 87, Issue:4

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Haptic Technology; H

2023
A pilot study of local anesthesia training using a mixed-reality haptic fidelity model.
    Journal of dental education, 2023, Volume: 87, Issue:4

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Haptic Technology; H

2023
A pilot study of local anesthesia training using a mixed-reality haptic fidelity model.
    Journal of dental education, 2023, Volume: 87, Issue:4

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Haptic Technology; H

2023
A pilot study of local anesthesia training using a mixed-reality haptic fidelity model.
    Journal of dental education, 2023, Volume: 87, Issue:4

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Haptic Technology; H

2023
Association Between Single-nucleotide Polymorphisms in Candidate Genes and Success of Pulpal Anesthesia after Inferior Alveolar Nerve Block.
    Journal of endodontics, 2023, Volume: 49, Issue:1

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Lidocaine;

2023
Efficacy of submucosal tramadol and lidocaine on success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis.
    Odontology, 2020, Volume: 108, Issue:3

    Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Mo

2020
Pre-operative ketorolac efficacy with different anesthetics, irrigants during single visit root canal treatment of mandibular molars with acute irreversible pulpitis.
    Australian endodontic journal : the journal of the Australian Society of Endodontology Inc, 2020, Volume: 46, Issue:3

    Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Dental Pulp Cavity; Double-Blind Method; Humans;

2020
Perception of discomfort during injection and the need for supplemental anesthesia in the intraosseous technique using 4% articaine.
    Acta odontologica latinoamericana : AOL, 2016, Volume: 29, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Double-Blind Method; F

2016
In Patients With Symptomatic Irreversible Pulpitis, Articaine is 3.6 Times More Efficacious Than Lidocaine in Achieving Anesthetic Success When Used for Supplementary Infiltration After Mandibular Block Anesthesia.
    The journal of evidence-based dental practice, 2017, Volume: 17, Issue:2

    Topics: Anesthetics, Local; Carticaine; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Pulpitis

2017
Inferior alveolar nerve block with articaine supplemented with articaine buccal infiltration gives better success rate than lidocaine, during endodontic management of patients with symptomatic irreversible pulpitis.
    The journal of evidence-based dental practice, 2013, Volume: 13, Issue:2

    Topics: Anesthesia, Local; Anesthetics, Local; Carticaine; Female; Humans; Lidocaine; Male; Nerve Block; Pul

2013
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
    Journal of endodontics, 2013, Volume: 39, Issue:8

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine;

2013
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
    Journal of endodontics, 2013, Volume: 39, Issue:8

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine;

2013
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
    Journal of endodontics, 2013, Volume: 39, Issue:8

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine;

2013
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
    Journal of endodontics, 2013, Volume: 39, Issue:8

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine;

2013
Study of the anesthetic efficacy of inferior alveolar nerve block using articaine in irreversible pulpitis.
    The journal of contemporary dental practice, 2014, Jan-01, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Epinephrine; Humans; Lidocain

2014
Incidence of missed inferior alveolar nerve blocks in vital asymptomatic subjects and in patients with symptomatic irreversible pulpitis.
    Journal of endodontics, 2015, Volume: 41, Issue:5

    Topics: Anesthesia, Dental; Anesthetics, Local; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Pulpitis;

2015
Buffered Lidocaine With Sodium Bicarbonate did not Increase Inferior Alveolar Nerve Block Success Rate in Patients Having Symptomatic Irreversible Pulpitis.
    The journal of evidence-based dental practice, 2016, Volume: 16, Issue:1

    Topics: Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Prospective Studies; P

2016
Anaesthetic efficacy of intraligamentary injection techniques on mandibular molars diagnosed with asymptomatic irreversible pulpitis: A retrospective study.
    Australian endodontic journal : the journal of the Australian Society of Endodontology Inc, 2017, Volume: 43, Issue:1

    Topics: Anesthesia, Dental; Anesthetics, Local; Humans; Lidocaine; Mandibular Nerve; Molar; Nerve Block; Pai

2017
Safe intrapulpal anaesthesia.
    British dental journal, 2017, 01-13, Volume: 222, Issue:1

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Dental Pulp; Humans; Injections; Lidocain

2017
2% mepivacaine seems to do better than 2% lidocaine in achieving successful anesthesia in posterior teeth with irreversible pulpitis.
    Journal of the American Dental Association (1939), 2017, Volume: 148, Issue:4

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; M

2017
Long buccal nerve block injection pain in patients with irreversible pulpitis.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 112, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthetics, Local; Benzocaine; Cheek; Epinephrine; Female; Hu

2011
The pharmacotherapy of pulpitis.
    Oral surgery, oral medicine, and oral pathology, 1962, Volume: 15

    Topics: Chloramphenicol; Dental Pulp; Dental Pulp Diseases; Humans; Lidocaine; Pulpitis; Triamcinolone

1962
Anesthetic efficacy of the supplemental X-tip intraosseous injection in patients with irreversible pulpitis.
    Journal of endodontics, 2003, Volume: 29, Issue:11

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Equipment Design; Female; Humans; Inject

2003
[Comparison of the painless effect of four anesthetic methods during pulpal treatment].
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2006, Volume: 24, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics; Anesthetics, Local; Bicuspid; Female; Humans; Injections; Li

2006
Interleukin-8 is increased in gingival crevicular fluid from patients with acute pulpitis.
    Journal of endodontics, 2008, Volume: 34, Issue:2

    Topics: Acute Disease; Adult; Anesthetics, Local; Female; Gingival Crevicular Fluid; Humans; Interleukin-8;

2008
Effect of pulp inflammation on nerve impulse quality with or without anesthesia.
    Journal of endodontics, 2008, Volume: 34, Issue:4

    Topics: Anesthetics, Local; Animals; Cats; Cuspid; Dental Pulp; Electric Stimulation; Lidocaine; Mandibular

2008
Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1997, Volume: 84, Issue:6

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid; Dental Pulp;

1997
Anesthetic efficacy of the supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in irreversible pulpitis.
    Journal of endodontics, 1998, Volume: 24, Issue:7

    Topics: Adult; Aged; Alveolar Process; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid;

1998
[Method of diagnosing pulpitis by tooth surface temperature (author's transl)].
    Josai Shika Daigaku kiyo. The Bulletin of the Josai Dental University, 1977, Volume: 6, Issue:1

    Topics: Humans; Lidocaine; Pulpitis; Temperature; Thermography; Tooth

1977
[Dental pulp analgesia before its amputation or removal].
    Czasopismo stomatologiczne, 1976, Volume: 29, Issue:5

    Topics: Anesthesia, Dental; Anesthesia, Local; Dental Pulp Cavity; Humans; Lidocaine; Pulpectomy; Pulpitis;

1976
Managing local anesthesia problems in the endodontic patient.
    Journal of the American Dental Association (1939), 1992, Volume: 123, Issue:5

    Topics: Anesthesia, Dental; Anesthesia, Local; Bupivacaine; Dental Pulp; Injections; Lidocaine; Mandible; Mo

1992
[Clinical and bacteriological studies of various corticoid preparations for the treatment of pulpitis].
    Deutsche zahnarztliche Zeitschrift, 1968, Volume: 23, Issue:2

    Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Chloramphenicol; Demeclocycline; Fema

1968
[Experimental and clinical studies on the problem of corticoid treatment of the dental pulp].
    Deutsche Stomatologie, 1971, Volume: 21, Issue:5

    Topics: Animals; Chloramphenicol; Cricetinae; Dental Pulp Capping; Dentinogenesis; Glucocorticoids; Humans;

1971