Page last updated: 2024-10-28

lidocaine and Indigestion

lidocaine has been researched along with Indigestion in 6 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The treatment of dyspepsia in the emergency department often consists of antacid in combination with viscous lidocaine, even though the specific etiology of the pain is frequently unknown."9.06The emergency department treatment of dyspepsia with antacids and oral lidocaine. ( Watson, WA; Welling, LR, 1990)
"A short-cut review was carried out to establish whether lidocaine is a useful adjuvant in the gastrointestinal cocktail of dyspepsia treatment."8.83Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. Use of lidocaine in the gastrointestinal cocktail for the treatment of dyspepsia. ( Bowman, J; Jones, J, 2006)
"The treatment of dyspepsia in the emergency department often consists of antacid in combination with viscous lidocaine, even though the specific etiology of the pain is frequently unknown."5.06The emergency department treatment of dyspepsia with antacids and oral lidocaine. ( Watson, WA; Welling, LR, 1990)
"A short-cut review was carried out to establish whether lidocaine is a useful adjuvant in the gastrointestinal cocktail of dyspepsia treatment."4.83Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. Use of lidocaine in the gastrointestinal cocktail for the treatment of dyspepsia. ( Bowman, J; Jones, J, 2006)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singh, GD1
Wong, GB1
Southard, JA1
Amsterdam, EA1
Berman, DA1
Porter, RS1
Graber, M1
Vilke, GM1
Jin, A1
Davis, DP1
Chan, TC1
Bowman, J1
Jones, J1
Sagar, J1
Chavan, VA1
Shah, DK1
Welling, LR1
Watson, WA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Pantoprazole vs Ranitidine in Dyspepsia in Emergency Department: A Randomized Controlled Trial.[NCT01737840]Phase 466 participants (Actual)Interventional2012-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Need for Additional Drug

The investigators are measuring the need for additional drug at the end of 60 minutes. (NCT01737840)
Timeframe: 60 th minute

Interventionparticipants (Number)
Pantoprazole13
Ranitidine8

Visual Analogue Scale Score

The investigators are measuring the change of pain from the baseline to the 30th and 60th minutes by visual anologue scale (VAS). Visual Analogue Scale measurement is between 0 (no pain) and 100 (worst pain). A decrease of 13 or 16 mm in VAS score is accepted as a minimum clinically significant change in pain. (NCT01737840)
Timeframe: 30th and 60th minutes

,
InterventionVisual Analogue Scale (Mean)
VAS score changes at 60 minutesVAS scores changes at 30 minutes
Pantoprazole39.627.6
Ranitidine42.328.3

Reviews

1 review available for lidocaine and Indigestion

ArticleYear
Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. Use of lidocaine in the gastrointestinal cocktail for the treatment of dyspepsia.
    Emergency medicine journal : EMJ, 2006, Volume: 23, Issue:11

    Topics: Adult; Analgesics; Antacids; Drug Therapy, Combination; Dyspepsia; Emergencies; Emergency Service, H

2006

Trials

3 trials available for lidocaine and Indigestion

ArticleYear
The GI Cocktail is no more effective than plain liquid antacid: a randomized, double blind clinical trial.
    The Journal of emergency medicine, 2003, Volume: 25, Issue:3

    Topics: Adult; Anesthetics, Local; Antacids; Atropine; Double-Blind Method; Drug Combinations; Drug Therapy,

2003
Prospective randomized study of viscous lidocaine versus benzocaine in a GI cocktail for dyspepsia.
    The Journal of emergency medicine, 2004, Volume: 27, Issue:1

    Topics: Adult; Aluminum Hydroxide; Anesthetics, Local; Antacids; Atropine; Benzocaine; Drug Combinations; Dr

2004
The emergency department treatment of dyspepsia with antacids and oral lidocaine.
    Annals of emergency medicine, 1990, Volume: 19, Issue:7

    Topics: Acute Disease; Aluminum Hydroxide; Antacids; Drug Combinations; Drug Therapy, Combination; Dyspepsia

1990

Other Studies

2 other studies available for lidocaine and Indigestion

ArticleYear
Food for thought: atrioventricular dissociation.
    The American journal of medicine, 2013, Volume: 126, Issue:12

    Topics: Aged; Antacids; Belladonna Alkaloids; Chest Pain; Drug Combinations; Dyspepsia; Electrocardiography;

2013
Acute parotiditis and facial nerve palsy--unusual side effects of Xylocaine spray.
    Endoscopy, 2007, Volume: 39 Suppl 1

    Topics: Acute Disease; Anesthetics, Local; Dyspepsia; Endoscopy, Digestive System; Facial Paralysis; Female;

2007