lidocaine has been researched along with Hypothermia, Accidental in 14 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine is an effective therapy for neonatal seizures; however, it is not widely used, presumably due to the risk of cardiac events." | 7.81 | Lidocaine-Associated Cardiac Events in Newborns with Seizures: Incidence, Symptoms and Contributing Factors. ( de Vries, LS; Schalkwijk, S; Toet, MC; van den Broek, MP; van Rooij, LG; Weeke, LC, 2015) |
| "Cerebral ischemia was induced in dogs on cardiopulmonary bypass circulation by stopping the pump." | 5.26 | Increase in extracellular potassium in the brain during circulatory arrest: effects of hypothermia, lidocaine, and thiopental. ( Astrup, J; Gjerris, F; Skovsted, P; Sørensen, HR, 1981) |
| "Lidocaine is an effective therapy for neonatal seizures; however, it is not widely used, presumably due to the risk of cardiac events." | 3.81 | Lidocaine-Associated Cardiac Events in Newborns with Seizures: Incidence, Symptoms and Contributing Factors. ( de Vries, LS; Schalkwijk, S; Toet, MC; van den Broek, MP; van Rooij, LG; Weeke, LC, 2015) |
| " Thorough preoperative patient evaluation, detailed informed consent, and perioperative care delivered in a safe environment can contribute to improved safety in plastic surgery." | 1.38 | Patient safety in plastic surgery. ( Tabbal, GN; Trussler, AP, 2012) |
| "SUN 1165 had no effect on clonic convulsions induced by pentetrazol and pictrotoxin in mice, while both mexiletine and lidocaine prolonged the duration of clonic convulsions." | 1.27 | General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system. ( Hashimoto, Y; Hatta, M; Hattori, Y; Hirotsu, I; Ishihara, T; Kihara, T; Kitakaze, Y; Miyata, T; Nakamura, S; Takahama, K, 1988) |
| "Cerebral ischemia was induced in dogs on cardiopulmonary bypass circulation by stopping the pump." | 1.26 | Increase in extracellular potassium in the brain during circulatory arrest: effects of hypothermia, lidocaine, and thiopental. ( Astrup, J; Gjerris, F; Skovsted, P; Sørensen, HR, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weeke, LC | 1 |
| Schalkwijk, S | 1 |
| Toet, MC | 1 |
| van Rooij, LG | 1 |
| de Vries, LS | 1 |
| van den Broek, MP | 1 |
| Vollmer, C | 1 |
| Nommensen, J | 1 |
| Watolla, M | 1 |
| Bauer, I | 1 |
| Picker, O | 1 |
| Trussler, AP | 1 |
| Tabbal, GN | 1 |
| CAHN, J | 1 |
| HEROLD, M | 1 |
| BALTHAZAR, A | 1 |
| VARSOS, A | 1 |
| FROMMEL, E | 1 |
| FLEURY, C | 1 |
| VON LEDEBUR, I | 1 |
| BEGUIN, M | 1 |
| GRIESEMER, RD | 1 |
| THOMAS, RW | 1 |
| FARBER, EM | 1 |
| ROTH, RJ | 1 |
| ASCHHEIM, E | 1 |
| EDDY, DD | 1 |
| EPINETTE, WW | 1 |
| Kenkel, JM | 1 |
| Lipschitz, AH | 1 |
| Luby, M | 1 |
| Kallmeyer, I | 1 |
| Sorokin, E | 1 |
| Appelt, E | 1 |
| Rohrich, RJ | 1 |
| Brown, SA | 1 |
| Brown, JW | 1 |
| Whitehurst, ME | 1 |
| Gordon, CJ | 1 |
| Carroll, RG | 1 |
| Astrup, J | 1 |
| Skovsted, P | 1 |
| Gjerris, F | 1 |
| Sørensen, HR | 1 |
| Matsukawa, T | 1 |
| Sessler, DI | 2 |
| Christensen, R | 1 |
| Ozaki, M | 1 |
| Schroeder, M | 1 |
| Kim-Lee, MH | 1 |
| Stokes, BT | 1 |
| McDonald, JS | 1 |
| Glosten, B | 1 |
| Hynson, J | 1 |
| McGuire, J | 1 |
| Hirotsu, I | 1 |
| Kihara, T | 1 |
| Nakamura, S | 1 |
| Hattori, Y | 1 |
| Hatta, M | 1 |
| Kitakaze, Y | 1 |
| Takahama, K | 1 |
| Hashimoto, Y | 1 |
| Miyata, T | 1 |
| Ishihara, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Ambient Temperature and Forced-air Warming on Intraoperative Core Temperature[NCT02715076] | 292 participants (Actual) | Interventional | 2016-01-31 | Completed | |||
| Effects of Preanesthetic Forced Air Warming and Administration of Warmed Intravascular Fluid on Preventing Hypothermia and Shivering During Cesarean Delivery Under Spinal Anesthesia[NCT03256786] | 50 participants (Actual) | Observational | 2017-07-12 | Completed | |||
| A Prospective Randomized Clinical Trial Evaluating the Effect of Convective Pre-warming on Intra-operative Thermoregulatory Capabilities in Patients Enrolled in the TIGER Anesthesia Perioperative Protocol[NCT03876808] | 10 participants (Actual) | Interventional | 2017-10-26 | Terminated (stopped due to Poor participant recruitment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Rate of core temperature change from 1 to 3 hours after induction of anesthesia (°C/hour ) linear mixed-effects model to assess the effects of ambient temperature, forced-air warming and their interaction on the rate of core temperature change during 1 to 3h after induction (NCT02715076)
Timeframe: from 1 to 3 hours after induction of anesthesia
| Intervention | degree C (Mean) |
|---|---|
| Ambient Temp 19°C & Passive Insulation | -0.18 |
| Ambient Temp 19°C & Forced-air Warming | 0.05 |
| Ambient Temp 21°C & Passive Insulation | -0.06 |
| Ambient Temp 21°C & Forced-air Warming | 0.07 |
| Ambient Temp 23°C & Passive Insulation | -0.05 |
| Ambient Temp 23°C & Forced-air Warming | 0.02 |
Change in core temperature between induction of anesthesia and end of skin preparation (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celsius (Mean) |
|---|---|
| Convective Pre-warming | -0.95 |
| Standard of Care | -0.53 |
Core body temperature measured intraoperatively (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celsius (Mean) |
|---|---|
| Convective Pre-warming | 36.0 |
| Standard of Care | 35.7 |
Change in skin temperature between arrival to the holding area and departure to the operating room, and arrival to the PACU (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celsius (Mean) | |
|---|---|---|
| Holding area to operating room departure | Holding area to arrival in PACU | |
| Convective Pre-warming | -0.03 | -0.07 |
| Standard of Care | 0.08 | -0.48 |
Differences in temperature changes between elderly (≥ 65 years) and younger patients (< 65 years). (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celcius (Mean) |
|---|---|
| Temperature before prewarming - Patients >65 years of age | |
| Standard of Care | 36.5 |
Differences in temperature changes between elderly (≥ 65 years) and younger patients (< 65 years). (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celcius (Mean) | |||
|---|---|---|---|---|
| Temperature before prewarming - Patients <65 years of age | Temperature before prewarming - Patients >65 years of age | Temperature after prewarming - Patients <65 years of age | Temperature after prewarming - Patients >65 years of age | |
| Convective Pre-warming | 36.5 | 36.6 | 36.5 | 36.4 |
1 trial available for lidocaine and Hypothermia, Accidental
| Article | Year |
|---|---|
Heat flow and distribution during epidural anesthesia.
Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans | 1995 |
Heat flow and distribution during epidural anesthesia.
Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans | 1995 |
Heat flow and distribution during epidural anesthesia.
Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans | 1995 |
Heat flow and distribution during epidural anesthesia.
Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans | 1995 |
13 other studies available for lidocaine and Hypothermia, Accidental
| Article | Year |
|---|---|
Lidocaine-Associated Cardiac Events in Newborns with Seizures: Incidence, Symptoms and Contributing Factors.
Topics: Anticonvulsants; Birth Weight; Bradycardia; Databases, Factual; Female; Gestational Age; Heart Rate; | 2015 |
Influence of thoracic epidural anesthesia on gastric oxygenation during hypothermia and hemorrhage.
Topics: Anesthesia, Epidural; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Dogs | 2016 |
Patient safety in plastic surgery.
Topics: Blood Loss, Surgical; Electronic Health Records; Evidence-Based Medicine; Humans; Hypertension; Hypo | 2012 |
[Usefulness of induced cardiac arrest in surgery of the bloodless heart under hypothermia].
Topics: Cardiac Surgical Procedures; Heart Arrest; Heart Arrest, Induced; Hypothermia; Lidocaine; Thoracic S | 1957 |
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine | 1962 |
LIPOGENESIS IN HUMAN SKIN. II. THE EFFECT OF PHYSICAL AND CHEMICAL FACTORS ON IN VITRO LIPOGENESIS FROM ACETATE.
Topics: Acetates; Adipogenesis; Anesthesia; Anesthesia, Local; Biopsy; Chromatography; Fatty Acids; Glucose; | 1963 |
ROLE OF TRAUMA IN ISOMORPHIC RESPONSE IN PSORIASIS.
Topics: Biomedical Research; Chymotrypsin; Humans; Hyaluronoglucosaminidase; Hypothermia; Hypothermia, Induc | 1965 |
Hemodynamic physiology and thermoregulation in liposuction.
Topics: Adult; Anesthesia, General; Body Temperature Regulation; Cardiac Output; Cardiovascular System; Embo | 2004 |
The Pre-Optic Anterior Hypothalamus (POAH) partially mediates the hypothermic response to hemorrhage in rats.
Topics: Adaptation, Physiological; Anesthetics, Local; Animals; Body Temperature Regulation; Hemorrhage; Hyp | 2005 |
Increase in extracellular potassium in the brain during circulatory arrest: effects of hypothermia, lidocaine, and thiopental.
Topics: Animals; Brain; Brain Ischemia; Cardiopulmonary Bypass; Cell Membrane Permeability; Dogs; Hypothermi | 1981 |
Procaine, lidocaine, and hypothermia inhibit calcium paradox in glial cells.
Topics: Analysis of Variance; Calcium; Carrier Proteins; Humans; Hypothermia; Lidocaine; Neuroglia; Procaine | 1994 |
Preanesthetic skin-surface warming reduces redistribution hypothermia caused by epidural block.
Topics: Adult; Anesthesia, Epidural; Body Temperature; Female; Hot Temperature; Humans; Hypothermia; Lidocai | 1993 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Body Temperature; Catalepsy; Cats; Central Ne | 1988 |