Page last updated: 2024-10-28

lidocaine and Hypotension

lidocaine has been researched along with Hypotension in 172 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Lidocaine induced dose-dependent arterial hypotension when combined with a defined level of general anaesthesia."9.09Unintentional hypotension from lidocaine infiltration during orthognathic surgery and general anaesthesia. ( Enlund, M; Krekmanov, L; Mentell, O, 2001)
"Lidocaine attenuated the hemodynamic and inflammatory responses to endotoxemia in rabbits."7.69Lidocaine attenuates the hypotensive and inflammatory responses to endotoxemia in rabbits. ( Kobayashi, T; Nakanuma, Y; Saito, K; Shibata, K; Taniguchi, T; Yamamoto, K, 1996)
" In contrast, ovine pregnancy does not enhance the toxicity of mepivacaine, a drug with properties similar to lidocaine."7.68Pregnancy does not alter lidocaine toxicity. ( Arthur, GR; Covino, BG; Finster, M; Morishima, HO, 1990)
"Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect."6.77Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012)
"Hypotension is a common side effect associated with spinal anesthesia."6.70Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine. ( Charuluxananan, S; Kyokong, O; Leerapun, R; Pothimamaka, S, 2001)
"Hypotension was defined as mean arterial pressure < 80% of baseline."6.69Epidural phenylephrine attenuates hypotension induced by alkalinized lidocaine epidural anesthesia. ( Cheng, JK; Mok, MS; Pan, MH; Wei, TT; Wu, KH, 1999)
"Lidocaine-based regimen for induction of anesthesia reduced the risk of postinduction hypotension in older patients compared to the fentanyl-based regimen."5.69Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial. ( Amin, SM; Arafa, AS; ElSayed, OS; Hasanin, A; Hassan, A; Khaled, D; Mostafa, M, 2023)
"His bradycardia was refractory to atropine."5.48Profound Prolonged Bradycardia and Hypotension after Interscalene Brachial Plexus Block with Bupivacaine. ( Lee, D; Nelson, M; Reda, L; Reens, A, 2018)
"Sepsis was induced by cecal ligation and puncture."5.40Adenosine, lidocaine and Mg2+ (ALM) induces a reversible hypotensive state, reduces lung edema and prevents coagulopathy in the rat model of polymicrobial sepsis. ( Dobson, GP; Griffin, MJ; Letson, HL, 2014)
" The primary outcome was the incidence of predefined hypotension, which was treated with administration of 4 mg ephedrine as often as needed."5.30Haemodynamic changes and incisional bleeding after scalp infiltration of dexmedetomidine with lidocaine in neurosurgical patients. ( Chang, WS; Choi, SH; Ha, SH; Heo, GA; Jeong, J; Kim, H; Min, KT, 2019)
"The routine use of fentanyl and midazolam prior to sheath removal leads to a reduction in pain perception and vasovagal incidence, whilst the routine use of local infiltration during sheath removal should be discouraged as it leads to more pain and a trend to more vasovagal reactions."5.12Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. ( French, JK; Juergens, CP; Kiat Ang, C; Leung, DY; Lo, S, 2007)
"Hypotension is the most frequent adverse event reported with intravenous amiodarone."5.11Lack of a hypotensive effect with rapid administration of a new aqueous formulation of intravenous amiodarone. ( Bailin, SJ; Borbola, J; Bridges, DE; Haffajee, CI; Kerin, NZ; Lakatos, F; Molnar, J; Paladino, WP; Sarosi, I; Somberg, JC; Tarjan, J; Timar, S, 2004)
"Lidocaine (2%) or saline with adrenaline (1:200,000) does cause temporary hypotension and other hemodynamic changes during general anesthesia, which last no longer than 4 minutes."5.11Marked hypotension induced by adrenaline contained in local anesthetic. ( Sun, J; Wang, QP; Wang, TY; Wang, ZY; Xu, JG; Yang, JJ; Zuo, D, 2005)
" The incidence of bradycardia was higher in the groups receiving meperidine."5.09Adding low dose meperidine to spinal lidocaine prolongs postoperative analgesia. ( Cicutti, N; Lui, AC; Murto, K, 1999)
"Lidocaine induced dose-dependent arterial hypotension when combined with a defined level of general anaesthesia."5.09Unintentional hypotension from lidocaine infiltration during orthognathic surgery and general anaesthesia. ( Enlund, M; Krekmanov, L; Mentell, O, 2001)
"Pain is a well known complication of propofol injection."5.08Modulating effects of lignocaine on propofol. ( Khoo, ST; Tham, CS, 1995)
"min-1), (2) the incidence of apnea and desaturation of oxygen (< 80%), (3) the degree of sedation, and (4) the serum levels of bilirubin and unbound bilirubin after surgery."5.08[Midazolam for anesthetic induction in neonates]. ( Iwasawa, K; Kadosaki, M; Kawakami, K; Mitono, H; Ohata, J; Saito, I, 1998)
"The relative safety and efficacy of intravenous administration of adenosine, lignocaine, disopyramide, flecainide, and sotalol for termination of stable, induced ventricular tachycardia was assessed in serial trials."5.06Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia. ( Camm, AJ; Garratt, CJ; Griffith, MJ; Linker, NJ; Ward, DE, 1990)
"5% NaCl + adenosine, lidocaine, and Mg/adenosine and lidocaine provided superior cardiovascular, acid-base, metabolic, and renal recoveries following severe hemorrhagic shock in the pig compared with 7."3.80Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation. ( Dobson, GP; Granfeldt, A; Hyldebrandt, JA; Letson, HL; Nielsen, TK; Salcedo, PA; Tønnesen, E; Vinten-Johansen, J; Wang, ER, 2014)
" Subdiaphragmatic vagotomy and abdominal perivagal lidocaine administration, or lidocaine injection into the nucleus tractus solitarius (NTS) prevented LPS hypotension."3.74Lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area. ( Cutrera, RA; Feleder, C; Goktalay, G; Millington, WR; Myer, BS; Yilmaz, MS, 2008)
" Hypotension (systemic arterial blood pressure less than 100 mmHg) occurred twice during dexmedetomidine administration, but was normolized by ephedrine administration."3.74[Use of high-dose dexmedetomidine infusion for anesthesia and sedation in a patient for microlaryngeal surgery maintained with spontaneous breathing]. ( Dohi, S; Ohata, H; Tanemura, E, 2008)
" Intravenous (iv) injection of PDG (10 microg/kg), produced hypotension, bradycardia and apnea over a period of time."3.70Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats. ( Bagchi, S; Deshpande, SB, 2000)
" Reversal of xylazine-induced sedation with tolazoline caused transient sinus bradycardia and sinus arrest, accompanied by severe systemic arterial hypotension."3.70Sedation with xylazine and lumbosacral epidural administration of lidocaine and xylazine for umbilical surgery in calves. ( Constable, PD; Huhn, JC; Lewis, CA; Morin, DE, 1999)
" During anaesthesia, all 10 patients required inotropic support to prevent hypotension, 4 patients required tracheal gas insufflation of oxygen to the operated lung to avoid hypoxaemia and 3 patients required lidocaine to treat ventricular arrhythmia."3.70Permissive hypercapnia during thoracic anaesthesia. ( Innami, Y; Kotake, Y; Morisaki, H; Serita, R; Takeda, J, 1999)
" After undergoing resection for femoral chondrosarcoma under epidural anesthesia, the patient received a continuous infusion of epidural morphine for postoperative analgesia."3.70Perioperative stroke associated with postoperative epidural analgesia. ( Benesch, CG; Francisco, DR; Wu, CL, 2000)
"Lidocaine attenuated the hemodynamic and inflammatory responses to endotoxemia in rabbits."3.69Lidocaine attenuates the hypotensive and inflammatory responses to endotoxemia in rabbits. ( Kobayashi, T; Nakanuma, Y; Saito, K; Shibata, K; Taniguchi, T; Yamamoto, K, 1996)
" In contrast, ovine pregnancy does not enhance the toxicity of mepivacaine, a drug with properties similar to lidocaine."3.68Pregnancy does not alter lidocaine toxicity. ( Arthur, GR; Covino, BG; Finster, M; Morishima, HO, 1990)
"The influence of hyperkalemia on the central nervous system and cardiac toxicity of bupivacaine and lidocaine was studied in open-chested mechanically ventilated dogs."3.67The influence of serum potassium on the cerebral and cardiac toxicity of bupivacaine and lidocaine. ( Avery, P; Redon, D; Rusy, B; Schaenzer, G, 1984)
"A 62-year-old man who was under observation following an episode of severe chest pain developed complete heart block and hypotension after receiving sublingual nitroglycerin."3.66Complete heart block after sublingual nitroglycerin. ( Fenster, PE; Lancaster, L, 1983)
" The ventricular arrhythmias responded to intravenous administration of lidocaine and to direct current electric shock; ventricular pacing was required in some instances and intravenous administration of propranolol combined with ventricular pacing in one."3.65Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. ( Chou, TC; Fowler, NO; Hanenson, IB; Holmes, JC; McCall, D, 1976)
"However, adverse events such as hypoxemia often occur clinically."3.11Effects of intravenous lidocaine on hypoxemia induced by propofol-based sedation for gastrointestinal endoscopy procedures: study protocol for a prospective, randomized, controlled trial. ( An, LX; Qi, XR; Sun, JY; Xue, FS; Zhang, K, 2022)
"Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect."2.77Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012)
"Bleeding was assessed after raising the craniotomy flap."2.73Hemodynamic changes due to infiltration of the scalp with epinephrine-containing lidocaine solution: a hypotensive episode before craniotomy. ( Cheng, HL; Li, WY; Shang, RJ; Shen, JC; Shi, JX; Wang, HD; Xu, JG; Yang, JJ, 2007)
"Hypotension is a common side effect associated with spinal anesthesia."2.70Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine. ( Charuluxananan, S; Kyokong, O; Leerapun, R; Pothimamaka, S, 2001)
"Hypotension was defined as mean arterial pressure < 80% of baseline."2.69Epidural phenylephrine attenuates hypotension induced by alkalinized lidocaine epidural anesthesia. ( Cheng, JK; Mok, MS; Pan, MH; Wei, TT; Wu, KH, 1999)
"His bradycardia was refractory to atropine."1.48Profound Prolonged Bradycardia and Hypotension after Interscalene Brachial Plexus Block with Bupivacaine. ( Lee, D; Nelson, M; Reda, L; Reens, A, 2018)
"kg(-1) bolus dosage given in 10 minutes."1.40Impact of perioperative lidocaine infusion and bis monitorization on remifentanil dosage in hypotensive anesthesia. ( Aypar, U; Erden, A; Uzun, S; Yuce, Y, 2014)
"Sepsis was induced by cecal ligation and puncture."1.40Adenosine, lidocaine and Mg2+ (ALM) induces a reversible hypotensive state, reduces lung edema and prevents coagulopathy in the rat model of polymicrobial sepsis. ( Dobson, GP; Griffin, MJ; Letson, HL, 2014)
"Amiodarone is a potent anti-arrhythmic with a large pharmacological spectrum that shares the mechanisms of action of all classes of anti-arrhythmic drugs."1.33Acute cardiodepressant effects induced by bolus intravenous administration of amiodarone in rabbits. ( Lessa, MA; Tibiriçá, E, 2005)
"LPS-induced hypotension has been attributed to nitric oxide (NO) activation of leukocytes, oxidants, cytokines, and other causes."1.31A role for abdominal vagal afferents in lipopolysaccharide-induced hypotension. ( Mailman, D, 2002)
"Hypotension and arrhythmias were treated with epinephrine, open-chest massage, and advanced cardiac life support protocols, respectively."1.31Cardiac resuscitation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine in anesthetized dogs. ( Butterworth, J; Deal, DD; Groban, L; James, RL; Vernon, JC, 2001)
" This prospective study of 53 consecutive healthy patients undergoing liposuction using a superwet technique served to develop general guidelines for safe perioperative fluid management, especially in regard to large-volume aspirations."1.30Safety considerations and fluid resuscitation in liposuction: an analysis of 53 consecutive patients. ( Adams, WP; Beran, SJ; Kenkel, JM; Klein, KW; Rohrich, RJ; Trott, SA, 1998)
"Sensitivity and specificity were 50% and 97%, respectively."1.29Factors associated with hypotension and bradycardia after epidural blockade. ( Curatolo, M; Orlando, A; Scaramozzino, P; Venuti, FS; Zbinden, AM, 1996)
"Hypotension was significantly greater after external jugular injections; these were also associated with larger reductions in heart rate."1.29Cardiorespiratory effects of intravascular injections of lidocaine in the anesthetized rat. Comparisons between arterial and venous routes of administration. ( Pateromichelakis, S, 1995)
"The child had asystole and grand mal seizures associated with lidocaine serum concentration of 19."1.27Intravenous lidocaine overdosage in a child. ( Edgren, B; Gehrz, R; Tilelli, J, 1986)
"In all animals in whom ventricular arrhythmias were associated with lidocaine, the arrhythmias spontaneously reverted to normal sinus rhythm."1.27Cardiovascular toxicity of local anesthetics: an alternative hypothesis. ( Behbehani, MM; Coyle, DE; Denson, DD; Thomas, RD, 1986)
" An identical sequence of toxic manifestations occurred in the adult, newborn, and fetus: convulsions, hypotension, respiratory arrest, and circulatory collapse."1.26Toxicity of lidocaine in adult, newborn, and fetal sheep. ( Bruce, SL; Covino, BG; Finster, M; Gutsche, BB; Morishima, HO; Pedersen, H; Sakuma, K; Stark, RI, 1981)
"Lidocaine toxicity was life-threatening or significantly complicated the management of 15 patients."1.26Excessive serum lidocaine levels during maintenance infusions: mechanisms and prevention. ( Atkinson, AJ; Davison, R; Parker, M, 1982)
"The occurrence of hypertensive crises, arrhythmias and hypotensive crises during surgery for pheochromocytoma can be prevented both preoperatively and intraoperatively by adequate alpha-adrenergic blockade and volume replacement."1.26[Medical support in surgery for pheochromocytoma]. ( Schmucki, O, 1979)

Research

Studies (172)

TimeframeStudies, this research(%)All Research%
pre-199077 (44.77)18.7374
1990's35 (20.35)18.2507
2000's40 (23.26)29.6817
2010's17 (9.88)24.3611
2020's3 (1.74)2.80

Authors

AuthorsStudies
Qi, XR1
Sun, JY1
An, LX1
Zhang, K1
Xue, FS1
Amin, SM1
Hasanin, A1
ElSayed, OS1
Mostafa, M1
Khaled, D1
Arafa, AS1
Hassan, A1
Letson, HL4
Granfeldt, A4
Jensen, TH1
Mattson, TH1
Dobson, GP5
Nelson, M1
Reens, A1
Reda, L1
Lee, D1
Kim, H1
Choi, SH1
Ha, SH1
Chang, WS1
Heo, GA1
Jeong, J1
Min, KT1
Clivatti, J1
Siddiqui, N1
Goel, A1
Shaw, M1
Crisan, I1
Carvalho, JC2
Nakamura, K1
Fukami, N1
Hyldebrandt, JA2
Wang, ER1
Salcedo, PA1
Nielsen, TK2
Tønnesen, E3
Vinten-Johansen, J3
Uzun, S1
Yuce, Y1
Erden, A1
Aypar, U1
Griffin, MJ1
Shi, W1
Ong, AA1
Farhood, Z1
Kyle, AR1
Patel, KG1
Lee, BH1
Braehler, M1
Yoshida, S2
Nishikawa, K2
Shimodate, Y2
Igarashi, M2
Namiki, A2
Yilmaz, MS2
Goktalay, G2
Millington, WR4
Myer, BS1
Cutrera, RA1
Feleder, C2
Malvasi, A1
Tinelli, A1
Stark, M1
Pontrelli, G1
Brizzi, A1
Wetzl, RG1
Benhamou, D1
Kruger, K1
Stegmann, GF1
Yorgancilar, E1
Gun, R1
Yildirim, M1
Bakir, S1
Akkus, Z1
Topcu, I1
Noel, J1
Temple, A1
Laycock, GJ1
Sølling, C1
Frøkiær, J1
Wogensen, L1
Van Haren, RM1
Proctor, KG1
Ayatollahi, V1
Behdad, S1
Kargar, S1
Yavari, T1
Pratt, S1
Vasudevan, A1
Hess, P1
Maher, CO1
Wetjen, NM1
Friedman, JA1
Meyer, FB1
Heslop, DJ1
Keay, KA2
Bandler, R2
Mailman, D1
Araújo, LD1
Singi, G1
Gazola, R1
Kamenik, M1
Raphael, JH1
Southall, JL1
Kitas, GD1
Lahlou, S1
Bagchi, S1
Deshpande, SB1
LEWIS, JM1
REES, GA1
MURRAY, BR1
ROBERTSON, DS1
WALTHER, WW1
SLACK, WK1
CHEW, HE1
BHARDWAJ, VB1
DENNIS, J1
ANSELL, G1
ANSELL, A1
KENNEDY, BR1
DUTHIE, AM1
PARBROOK, GD1
CARR, TL1
MORALES AGUILERA, A1
VAUGHANWILLIAMS, EM1
Mioni, C1
Giuliani, D1
Cainazzo, MM1
Leone, S1
Iannone, A1
Bazzani, C1
Grieco, P1
Novellino, E1
Tomasi, A1
Bertolini, A1
Guarini, S1
Somberg, JC1
Timar, S1
Bailin, SJ1
Lakatos, F1
Haffajee, CI1
Tarjan, J1
Paladino, WP1
Sarosi, I1
Kerin, NZ1
Borbola, J1
Bridges, DE1
Molnar, J1
Promphan, W1
Sopontammarak, S1
Pruekprasert, P1
Kajornwattanakul, W1
Kongpattanayothin, A1
Yang, JJ3
Wang, QP2
Wang, TY1
Sun, J2
Wang, ZY2
Zuo, D1
Xu, JG3
Lessa, MA1
Tibiriçá, E1
Heckmann, JG1
Maihöfner, C1
Lanz, S1
Rauch, C1
Neundörfer, B1
Pajolla, GP1
Tavares, RF1
Pelosi, GG1
Corrêa, FM1
Li, WY2
Jil, Q1
Li, ZQ1
Caliskan, E1
Bodur, H1
Baykara, N1
Eren, L1
Yucesoy, I1
Cavun, S2
Levendusky, MC1
Resch, GE1
Veno, PA1
Bjørnestad, E1
Iversen, OL1
Raeder, J1
Pippa, P1
Cuomo, P1
Panchetti, A1
Scarchini, M1
Poggi, G1
D'Arienzo, M1
Enlund, M2
Kiat Ang, C1
Leung, DY1
Lo, S1
French, JK1
Juergens, CP1
Cheng, HL1
Shang, RJ1
Shen, JC1
Shi, JX1
Wang, HD1
Whitty, RJ1
Maxwell, CV1
Evans, L1
Adekanye, O1
Iff, I1
Moens, Y1
Yi, HJ1
Kim, DW1
Suh, JK1
Ohata, H1
Tanemura, E1
Dohi, S1
Hoff, RG1
VAN Dijk, GW1
Mettes, S1
Verweij, BH1
Algra, A1
Rinkel, GJ1
Kalkman, CJ1
Lancaster, L1
Fenster, PE1
Avery, P1
Redon, D1
Schaenzer, G1
Rusy, B1
Kuch, J1
Lubiszewska, B1
Pine, R1
Avellone, JC1
Hoffman, M1
Plecha, FR1
Swayngim, DM1
Urban, J1
Begara Mesa, D1
Vilar Rodriguez, MA1
Kirpatovskiĭ, VI1
Onishchenko, NA1
Lubiako, AA1
Danilov, MA1
Bogoiavlenskaia, TA1
Tydén, G1
Samnegård, H1
Thulin, L1
Hindman, MC1
Wagner, GS1
Drake, CE1
Carpenter, P1
Gobel, FL1
Hulsing, DJ1
Davison, R1
Parker, M1
Atkinson, AJ1
Feely, J1
Wade, D1
McAllister, CB1
Wilkinson, GR1
Robertson, D1
Vasconcelos Palacios, G1
Hernández Clemente, J1
Hernández Menindez, G1
Abboud, TK1
Khoo, SS1
Miller, F1
Doan, T1
Henriksen, EH1
Morishima, HO2
Pedersen, H1
Finster, M2
Sakuma, K1
Bruce, SL1
Gutsche, BB1
Stark, RI1
Covino, BG2
Economacos, G1
Skountzos, V1
Johannsen, UJ1
Summers, R1
Mark, AL1
Harukuni, I1
Yamaguchi, H1
Sato, S1
Naito, H1
Pateromichelakis, S1
Tham, CS1
Khoo, ST1
Halpern, S1
Glanc, P1
Myhr, T1
Ryan, M1
Fong, K1
Amankwah, K1
Ohlsson, A1
Guo, X1
Phillips, S1
Hutchinson, SE1
Bayly, P1
Hollway, TE1
Fortuna, A1
Kafle, SK1
Collier, CB1
Gatt, SP1
Lockley, SM1
Tanaka, M1
Taniguchi, T1
Shibata, K1
Yamamoto, K1
Kobayashi, T1
Saito, K1
Nakanuma, Y1
Reinhart, DJ1
Wang, W1
Stagg, KS1
Walker, KG1
Bailey, PL1
Walker, EB1
Zaugg, SE1
Curatolo, M1
Scaramozzino, P1
Venuti, FS1
Orlando, A1
Zbinden, AM1
Dreskin, S1
Bajwa, ZH1
Lehmann, L1
Warfield, CA1
Kawakami, K1
Ohata, J1
Kadosaki, M1
Saito, I1
Iwasawa, K1
Mitono, H1
Henderson, LA1
Trott, SA1
Beran, SJ1
Rohrich, RJ1
Kenkel, JM1
Adams, WP1
Klein, KW1
Lewis, CA1
Constable, PD1
Huhn, JC1
Morin, DE1
Murto, K1
Lui, AC1
Cicutti, N1
Rao, RB1
Ely, SF1
Hoffman, RS1
Cheng, JK1
Pan, MH1
Wu, KH1
Mok, MS1
Wei, TT1
Takagi, A1
Morisaki, H1
Serita, R1
Innami, Y1
Kotake, Y1
Takeda, J1
Wu, CL1
Francisco, DR1
Benesch, CG1
Groban, L1
Deal, DD1
Vernon, JC1
James, RL1
Butterworth, J1
Mentell, O1
Krekmanov, L1
Jones, RS1
Kyokong, O1
Charuluxananan, S1
Pothimamaka, S1
Leerapun, R1
Fowler, NO1
McCall, D1
Chou, TC1
Holmes, JC1
Hanenson, IB1
Valle, LB1
Oliveira-Filho, RM1
Armonia, PL1
Nassif, M1
Saraceni, G1
Moir, DD1
Slater, PJ1
Thorburn, J2
McLaren, R1
Moodie, J1
Curelaru, I1
Schmucki, O1
Zoll, WR1
Täuber, M1
Vorburger, C1
DeVore, JS1
Harnacke, P1
Strasser, K1
Beck, L1
Waxman, MB1
Asta, JA1
Cameron, DA1
Endrenyi, L1
Fung, BK1
Gislefoss, AJ1
Ho, ES1
D'Eramo, EM1
Jordan, DA1
Miller, ED1
Griffith, MJ1
Linker, NJ1
Garratt, CJ1
Ward, DE2
Camm, AJ1
Griffis, CA1
Luntley, JB1
Van Hasselt, G1
Chestnut, DH1
Pollack, KL1
Thompson, CS1
DeBruyn, CS1
Weiner, CP1
Hardy, SG1
Mack, SM1
Arthur, GR1
Clément, G1
Arbez-Gindre, F1
Lassauge, F1
Barale, F1
Scott, DB1
Crochetière, CT1
Trépanier, CA1
Coté, JJ1
Ullman, DA1
Schmitt, L1
Petin, GI1
Strelets, BM1
Krasavin, VA1
Shah, K1
Karlman, R1
Heller, J1
Armstrong, DK1
Bremseth, DL1
Lima, JJ1
Zhuang, XL1
Reid, JA1
Mantia, AM1
Phillips, OC1
Parnass, SM1
Curran, MJ1
Becker, GL1
Edgren, B1
Tilelli, J1
Gehrz, R1
Cheesman, M1
Thomas, RD1
Behbehani, MM1
Coyle, DE1
Denson, DD1
Pitt, A1
Lipp, H1
Anderson, ST1
Iffy, L1
Campbell, NP1
Kelly, JG1
Shanks, RG1
Chaturvedi, NC1
Strong, JE1
Pantridge, JF1
Sehhati, G1
Frey, R1
Mildner, R1
Flensted-Jensen, E1
Sandoe, E1
Davis, JL1
Resnekov, L1
Späth, G1
Shimosato, S1
McDonald, JS1
Bjorkman, LL1
Reed, EC1
Raynaud, R1
Brochier, M1
Fauchier, JP1
Raynaud, P1
Binder, C1
Wimmer, M1
Irstam, L1
Marriott, HJ1
Phillips, K1
Keats, AS1
Strong, MJ1
Girgis, KZ1
Goldstein, A1
Patton, RD1
Shnider, SM1
Schifrin, BS1
Zelis, R1
Porciello, PI1
Zanini, S1
Poppi, A1
Fisher, A1
Bryce-Smith, R1
Frink, RJ1
James, TN1
Hendrickson, M1
Fisher, J1
James, ML1
Lee, JA1
Wishart, HY1
Fox, GS1
Houle, GL1
Orr, D1
Jones, I1
Chopra, MP1
Portal, RW1
Aber, CP1
Bromage, PR1
Albert, ML1
Greer, WE1
Kantrowitz, W1
Lamont, NM1
Posel, K1
Morera Marco, V1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Intravenous Lidocaine Reduce Propofol Consumption and the Side Effects of Sedation During Gastroscopy in ASA 1 and 2 Patients.[NCT05944887]46 participants (Actual)Interventional2023-07-21Completed
Is the Application of Scopolamine Patch With or Without Intra-operative Acupressure Point P6 Stimulation More Effective Than Intra-operative Acupressure Point P6 Stimulation Alone?[NCT02960113]Phase 4240 participants (Actual)Interventional2016-05-31Completed
A Study of the Trigeminal Cardio-Reflex in Endodontic and Other Dental Treatment[NCT02745782]500 participants (Anticipated)Observational2014-10-31Recruiting
Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery[NCT05867342]Phase 440 participants (Actual)Interventional2017-05-12Completed
Low Epidural Anesthesia With Chloroprocaine Versus Lidocaine: a Prospective, Randomized, Double-blinded Multi-centre Clinical Trial in China[NCT02287870]Phase 4120 participants (Actual)Interventional2008-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Level of Nausea After Eversion of the Uterus

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after eversion of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After eversion of the uterus until replacement of the uterus

Interventionunits on a scale (Mean)
Scopolamine Patch1.28
Acupressure Point P61.09
Scopolamine Patch + Acupressure Point P61.40

Level of Nausea After Replacement of the Uterus

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after replacement of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After replacement of the uterus and to the next 15 minutes

Interventionunits on a scale (Mean)
Scopolamine Patch2.19
Acupressure Point P62.19
Scopolamine Patch + Acupressure Point P62.51

Level of Nausea After the Administration of the Regional Anesthesia Medications

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after the administration of the regional anesthesia medications. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: From administration of anaesthesia until eversion of uterus

Interventionunits on a scale (Mean)
Scopolamine Patch2.71
Acupressure Point P62.57
Scopolamine Patch + Acupressure Point P62.84

Level of Nausea Upon Arrival to the Post-operative Recovery Room

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) upon arrival to the post-operative recovery room. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: 15 minutes after replacement of the uterus to arrival at post-anaesthesia care unit

Interventionunits on a scale (Mean)
Scopolamine Patch0.18
Acupressure Point P60.25
Scopolamine Patch + Acupressure Point P60.23

Number of Patients With Nausea

The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea at any point during the surgical procedure in each group. (NCT02960113)
Timeframe: Throughout the entire surgical procedure

InterventionParticipants (Count of Participants)
Scopolamine Patch40
Acupressure Point P639
Scopolamine Patch + Acupressure Point P646

Number of Patients With Vomiting

The investigators will perform objective assessments of whether or not the patients have vomited during the procedure. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: Throughout the surgical procedure

InterventionParticipants (Count of Participants)
Scopolamine Patch24
Acupressure Point P625
Scopolamine Patch + Acupressure Point P631

Number of Patients With Vomiting After Eversion of the Uterus

Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After eversion of to replacement of the uterus

InterventionParticipants (Count of Participants)
Scopolamine Patch8
Acupressure Point P66
Scopolamine Patch + Acupressure Point P69

Number of Patients With Vomiting After Replacement of the Uterus

Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After replacement of the uterus and for next 15 minutes

InterventionParticipants (Count of Participants)
Scopolamine Patch10
Acupressure Point P615
Scopolamine Patch + Acupressure Point P612

Number of Patients With Vomiting After the Administration of the Regional Anesthesia Medications

Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After the administration of the regional anesthesia medications until eversion of the uterus

InterventionParticipants (Count of Participants)
Scopolamine Patch20
Acupressure Point P615
Scopolamine Patch + Acupressure Point P620

Number of Patients With Vomiting Upon Arrival to the Post-operative Recovery Room

Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: From 15 minutes after replacement of the uterus until arrival at the post-anaesthesia care unit

InterventionParticipants (Count of Participants)
Scopolamine Patch1
Acupressure Point P61
Scopolamine Patch + Acupressure Point P64

Satisfaction With Intraoperative Antiemetic Treatment

Patients are asked their nausea and vomiting treatment satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Patients are also asked their overall satisfaction with the procedure (0 = Not Satisfied, 10 = Extremely Satisfied). (NCT02960113)
Timeframe: Throughout the surgical procedure

Interventionunits on a scale (Mean)
Scopolamine Patch9.29
Acupressure Point P68.96
Scopolamine Patch + Acupressure Point P69.59

Duration of Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionminutes (Mean)
1:1000 Epinephrine Plus Saline72.05
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine54.23

Estimated Blood Loss During Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

InterventionmL (Mean)
1:1000 Epinephrine Plus Saline95.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine91.63

Number of Days With Postoperative Bloody Nasal Discharge

Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventiondays (Mean)
1:1000 Epinephrine Plus Saline2.85
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.73

Number of Extra Pledgets Used

A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionpledgets (Mean)
1:1000 Epinephrine Plus Saline3.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.63

Number of Nostrils With Continuous Fresh Bleeding

Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionnostrils (Count of Units)
1:1000 Epinephrine Plus Saline7
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine5

Postoperative Bloody Discharge Grading Score

Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline2.38
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.2

Surgical Field Grading Score

The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline3.54
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine3.23

Reviews

9 reviews available for lidocaine and Hypotension

ArticleYear
Interventions to Decrease Postoperative Edema and Ecchymosis after Rhinoplasty: A Systematic Review of the Literature.
    Plastic and reconstructive surgery, 2016, Volume: 137, Issue:5

    Topics: Adrenal Cortex Hormones; Blood Loss, Surgical; Ecchymosis; Edema; Fibrin Tissue Adhesive; Humans; Hy

2016
[Extradural anesthesia in cesarean operations].
    Revista espanola de anestesiologia y reanimacion, 1982, Volume: 29, Issue:4

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Section; Ep

1982
Arrhythmias during myocardial infarction: Mechanisms, significance, and therapy.
    Cardiovascular clinics, 1980, Volume: 11, Issue:1

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Bradycardia; Heart Block; Humans;

1980
[Toxic and adverse effects of local anesthetics/neuromuscular blocker: lidocaine, succinylcholine].
    Ryoikibetsu shokogun shirizu, 1999, Issue:27 Pt 2

    Topics: Anesthetics, Local; Drug Interactions; Humans; Hypokalemia; Hypotension; Lidocaine; Muscle Rigidity;

1999
Epidural analgesia in the dog and cat.
    Veterinary journal (London, England : 1997), 2001, Volume: 161, Issue:2

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Cats; Dogs; Epidu

2001
Cardiac arrhythmias. 6. Present status of electroversion in the management of cardiac dysrhythmias.
    Circulation, 1973, Volume: 47, Issue:6

    Topics: Anticoagulants; Arrhythmias, Cardiac; Atrial Flutter; Cardiomegaly; Digitalis Glycosides; Electric C

1973
[Intensive medicine. Myocardial infarct].
    Munchener medizinische Wochenschrift (1950), 1972, Jan-21, Volume: 114, Issue:3

    Topics: Arrhythmias, Cardiac; Coronary Care Units; Diagnosis, Differential; Digitalis Glycosides; Fibrinolyt

1972
Circulatory adjustments under spinal anesthesia.
    International anesthesiology clinics, 1974,Spring, Volume: 12, Issue:1

    Topics: Anesthesia, Epidural; Anesthesia, Spinal; Arteries; Blood Circulation; Blood Pressure; Cardiac Outpu

1974
Management of arrhythmias in acute myocardial infarction.
    American family physician, 1971, Volume: 4, Issue:1

    Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O

1971

Trials

37 trials available for lidocaine and Hypotension

ArticleYear
Effects of intravenous lidocaine on hypoxemia induced by propofol-based sedation for gastrointestinal endoscopy procedures: study protocol for a prospective, randomized, controlled trial.
    Trials, 2022, Sep-24, Volume: 23, Issue:1

    Topics: Conscious Sedation; Endoscopy, Gastrointestinal; Humans; Hypotension; Hypoxia; Lidocaine; Midazolam;

2022
Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial.
    Anaesthesia, critical care & pain medicine, 2023, Volume: 42, Issue:4

    Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Emergence Delirium; Fentany

2023
Haemodynamic changes and incisional bleeding after scalp infiltration of dexmedetomidine with lidocaine in neurosurgical patients.
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Blood Pressure; Dexmedetomidine; Drug Therapy

2019
[Efficacy of spinal anesthesia with small-dose lidocaine in ambulatory prostate biopsy procedures for elderly patients : comparison with propofol anesthesia].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:5

    Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, General; Anesthesia, Spinal; Biopsy; Humans; Hypot

2008
Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial.
    Acta medica Iranica, 2012, Volume: 50, Issue:9

    Topics: Adult; Anesthetics, Intravenous; Bradycardia; Double-Blind Method; Ephedrine; Female; Humans; Hypote

2012
A prospective randomized trial of lidocaine 30 mg versus 45 mg for epidural test dose for intrathecal injection in the obstetric population.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:1

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Cesare

2013
Intraoperative lidocaine injection into the carotid sinus during endarterectomy.
    Journal of neurosurgery, 2002, Volume: 97, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Carotid Sinus; Endarterectomy, Carotid; Female; Humans;

2002
Lack of a hypotensive effect with rapid administration of a new aqueous formulation of intravenous amiodarone.
    The American journal of cardiology, 2004, Mar-01, Volume: 93, Issue:5

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Hypotension; Infusions,

2004
Marked hypotension induced by adrenaline contained in local anesthetic.
    The Laryngoscope, 2005, Volume: 115, Issue:2

    Topics: Anesthesia, General; Anesthetics, Local; Blood Pressure; Double-Blind Method; Epinephrine; Female; H

2005
Local anesthesia for functional endoscopic sinus surgery employing small volumes of epinephrine-containing solutions of lidocaine produces profound hypotension.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:10

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Local; Double-Blind Meth

2005
Similar onset time of 2-chloroprocaine and lidocaine + epinephrine for epidural anesthesia for elective Cesarean section.
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:3

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Cesarean Section; Double-B

2006
High volume and low concentration of anaesthetic solution in the perivascular interscalene sheath determines quality of block and incidence of complications.
    European journal of anaesthesiology, 2006, Volume: 23, Issue:10

    Topics: Adrenergic Agonists; Adult; Aged; Anesthetics, Local; Brachial Plexus; Bradycardia; Bupivacaine; Epi

2006
Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention.
    International journal of cardiology, 2007, Apr-04, Volume: 116, Issue:3

    Topics: Aged; Anesthetics, Local; Angioplasty, Balloon, Coronary; Bradycardia; Cardiovascular Diseases; Cons

2007
Hemodynamic changes due to infiltration of the scalp with epinephrine-containing lidocaine solution: a hypotensive episode before craniotomy.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Loc

2007
A comparison of spinal anesthesia with small-dose lidocaine and general anesthesia with fentanyl and propofol for ambulatory prostate biopsy procedures in elderly patients.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia Recovery P

2007
The comparison of epidural fentanyl, epidural lidocaine, and intravenous fentanyl in patients undergoing gastrectomy.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:6

    Topics: Adjuvants, Anesthesia; Adrenocorticotropic Hormone; Adult; Aged; Analgesics; Anesthesia, Epidural; A

1995
Modulating effects of lignocaine on propofol.
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Anesthesia, Intravenous; Female; Forearm; Hand; Hu

1995
Adrenaline-induced hypotension in neurosurgery.
    British journal of anaesthesia, 1993, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Blood Pressure; Brain; Depression, Ch

1993
Intrathecal meperidine for elective caesarean section: a comparison with lidocaine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:8

    Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Apgar Score; Cesarean Section; Female; Humans;

1993
Epidural test dose: isoproterenol is a reliable marker for intravascular injection in anesthetized adults.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Inhalation; Biomarkers; Blood Pressure; Female; Heart Rate

1996
Postoperative analgesia after peripheral nerve block for podiatric surgery: clinical efficacy and chemical stability of lidocaine alone versus lidocaine plus clonidine.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Analgesia; Analgesics; Analysis of Variance; Anesthetics, Local; A

1996
[Midazolam for anesthetic induction in neonates].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:5

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Bilirubin; Blood Press

1998
Adding low dose meperidine to spinal lidocaine prolongs postoperative analgesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:4

    Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Analysis of Variance;

1999
Epidural phenylephrine attenuates hypotension induced by alkalinized lidocaine epidural anesthesia.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:6

    Topics: Aged; Anesthesia, Epidural; Anesthetics, Local; Blood Pressure; Double-Blind Method; Female; Heart R

1999
Unintentional hypotension from lidocaine infiltration during orthognathic surgery and general anaesthesia.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Anesthesia, General; Anesthetics, Local; Dose-Response Relationship, Drug; Female

2001
Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84 Suppl 1

    Topics: Adult; Anesthesia, Spinal; Blood Pressure Determination; Bupivacaine; Cesarean Section; Chi-Square D

2001
Extradural analgesia in obstetrics: a controlled trial of carbonated lignocaine and bupivacaine hydrochloride with or without adrenaline.
    British journal of anaesthesia, 1976, Volume: 48, Issue:2

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Back Pain; Bupivacaine; Epinephrine; Female; Headache

1976
Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia.
    Lancet (London, England), 1990, Sep-15, Volume: 336, Issue:8716

    Topics: Adenosine; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Disopyramid

1990
Epidural anaesthesia for caesarean section: comparison of two injection techniques.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:2

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Catheters, Indwelling; Cesarean Section; Clinical Tri

1989
Extradural bupivacaine or lignocaine anaesthesia for elective caesarean section: the role of maternal posture.
    British journal of anaesthesia, 1988, Volume: 61, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Female; Humans;

1988
Incidence of hypotension associated with epidural anesthesia using alkalinized and nonalkalinized lidocaine for cesarean section.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:11

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Pressure; Cesarean Section; Double-Blind Method

1987
Lignocaine given prophylactically to patients with acute myocardial infarction.
    Lancet (London, England), 1971, Mar-27, Volume: 1, Issue:7700

    Topics: Acute Disease; Arrhythmias, Cardiac; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans

1971
Mexiletine (Kö 1173) in the management of ventricular dysrhythmias.
    Lancet (London, England), 1973, Aug-25, Volume: 2, Issue:7826

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes,

1973
Epidural analgesia for obstetrics: a maternal, fetal, and neonatal study.
    American journal of obstetrics and gynecology, 1974, Dec-15, Volume: 120, Issue:8

    Topics: Acid-Base Equilibrium; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Carbon Dioxide; C

1974
Spinal analgesic agents. A comparison of cinchocaine, lignocaine and prilocaine.
    Anaesthesia, 1971, Volume: 26, Issue:3

    Topics: Anesthesia, Spinal; Dibucaine; Female; Headache; Humans; Hypotension; Lidocaine; Prilocaine; Time Fa

1971
Blood gas changes during spinal and epidural analgesia.
    Anaesthesia, 1969, Volume: 24, Issue:4

    Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Spinal; Carbon Dioxide; Cardia

1969
Anaesthesia for laryngoscopy. A comparison of the cardiovascular effects of cocaine and lignocaine.
    Anaesthesia, 1968, Volume: 23, Issue:2

    Topics: Aged; Anesthesia, Intravenous; Anesthesia, Local; Cardiovascular System; Cocaine; Heart; Heart Rate;

1968

Other Studies

126 other studies available for lidocaine and Hypotension

ArticleYear
Adenosine, Lidocaine, and Magnesium Support a High Flow, Hypotensive, Vasodilatory State With Improved Oxygen Delivery and Cerebral Protection in a Pig Model of Noncompressible Hemorrhage.
    The Journal of surgical research, 2020, Volume: 253

    Topics: Adenosine; Animals; Brain; Brain Chemistry; Disease Models, Animal; Drug Administration Schedule; Dr

2020
Profound Prolonged Bradycardia and Hypotension after Interscalene Brachial Plexus Block with Bupivacaine.
    The Journal of emergency medicine, 2018, Volume: 54, Issue:3

    Topics: Aged; Anesthetics, Local; Atropine; Brachial Plexus Block; Bradycardia; Bupivacaine; Emergency Servi

2018
Quality of labour neuraxial analgesia and maternal satisfaction at a tertiary care teaching hospital: a prospective observational study.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:8

    Topics: Adjuvants, Anesthesia; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Contro

2013
Altered responses to vasopressors of a patient medicated with carvedilol, pilsicainide and enalapril.
    Journal of anesthesia, 2014, Volume: 28, Issue:4

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Atria

2014
Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation.
    Critical care medicine, 2014, Volume: 42, Issue:5

    Topics: Adenosine; Animals; Blood Volume; Disease Models, Animal; Drug Therapy, Combination; Female; Fluid T

2014
Impact of perioperative lidocaine infusion and bis monitorization on remifentanil dosage in hypotensive anesthesia.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:4

    Topics: Adenoma; Adolescent; Adult; Aged; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Loca

2014
Adenosine, lidocaine and Mg2+ (ALM) induces a reversible hypotensive state, reduces lung edema and prevents coagulopathy in the rat model of polymicrobial sepsis.
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:3

    Topics: Adenosine; Animals; Blood Coagulation Disorders; Disease Models, Animal; Drug Therapy, Combination;

2014
Adenosine, lidocaine and Mg2+ improves cardiac and pulmonary function, induces reversible hypotension and exerts anti-inflammatory effects in an endotoxemic porcine model.
    Critical care (London, England), 2014, Dec-11, Volume: 18, Issue:6

    Topics: Adenosine; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Drug Therapy, Combination; End

2014
Use of test dose allows early detection of subdural local anesthetic injection with lumbar plexus block.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Anesthesia, Epidural; Anesthetics, Local; Antiemetics; Arthroplasty, Replacement, Hip; Ephedrine; Fe

2017
Lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area.
    Journal of neuroimmunology, 2008, Oct-15, Volume: 203, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Hypotension; Lidocaine; Li

2008
Low-dose sequential combined spinal-epidural anaesthesia in elective Stark caesarean section: a preliminary cohort study.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Bradycardia

2010
Partial intravenous anaesthesia in 5 horses using ketamine, lidocaine, medetomidine and halothane.
    Journal of the South African Veterinary Association, 2009, Volume: 80, Issue:4

    Topics: Acepromazine; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics; Anesthetics, Combine

2009
Determination of trigeminocardiac reflex during rhinoplasty.
    International journal of oral and maxillofacial surgery, 2012, Volume: 41, Issue:3

    Topics: Adult; Anesthetics, Local; Blood Pressure; Bradycardia; Epinephrine; Female; Heart Rate; Humans; Hyp

2012
A case report of anaphylaxis to chlorhexidine during urinary catheterisation.
    Annals of the Royal College of Surgeons of England, 2012, Volume: 94, Issue:4

    Topics: Aged; Anaphylaxis; Anti-Infective Agents, Local; Arthroplasty, Replacement, Hip; Chlorhexidine; Drug

2012
Adenocaine and Mg(2+) reduce fluid requirement to maintain hypotensive resuscitation and improve cardiac and renal function in a porcine model of severe hemorrhagic shock*.
    Critical care medicine, 2012, Volume: 40, Issue:11

    Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Female; Fluid Therapy; Heart; Hypoten

2012
Clinically relevant animal models needed to advance state of the art fluid resuscitation*.
    Critical care medicine, 2012, Volume: 40, Issue:11

    Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Female; Fluid Therapy; Heart; Hypoten

2012
Haemorrhage-evoked compensation and decompensation are mediated by distinct caudal midline medullary regions in the urethane-anaesthetised rat.
    Neuroscience, 2002, Volume: 113, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Blood Pressure; Exci

2002
A role for abdominal vagal afferents in lipopolysaccharide-induced hypotension.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:2

    Topics: Animals; Blood Pressure Determination; Capsaicin; Disease Models, Animal; Drug Interactions; Female;

2002
Verification of protector effect of the norepinephrine and felypressin upon the cardiovascular system under action of the lidocaine hydrochloride and prilocaine hydrochloride in anesthetized rats.
    Pharmacological research, 2002, Volume: 46, Issue:2

    Topics: Anesthesia; Anesthetics, Local; Animals; Blood Pressure; Drug Combinations; Electrocardiography; Fel

2002
Spontaneous restoration of decreased systemic vascular resistance after spinal anaesthesia.
    European journal of anaesthesiology, 2002, Volume: 19, Issue:11

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Cardiac Output; Female; Heart Rate; H

2002
Adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome.
    Rheumatology (Oxford, England), 2003, Volume: 42, Issue:1

    Topics: Adult; Aged; Female; Fibromyalgia; Humans; Hypertension, Pulmonary; Hypotension; Infusions, Intraven

2003
Mechanisms underlying the cardiovascular responses to spinal dopamine receptor stimulation by apomorphine in anesthetized rats.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Apomorphine; Atenolol;

2003
Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats.
    Indian journal of experimental biology, 2000, Volume: 38, Issue:9

    Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Apnea; Biguanides; Blood Pressure; Bradyc

2000
ELECTROCARDIOGRAPHY DURING POSTERIOR FOSSA OPERATIONS.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Arrhythmias, Cardiac; Electrocardiography; Embolism; Embolism, Air; Humans; Hypotension; Infant; Lid

1964
ANAESTHESIA FOR MITRAL VALVOTOMY COMPLICATED BY HYPOTENSION DUE TO PERICARDIAL EFFUSION. REPORT OF TWO CASES.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesiology; Cardiac Surgical Procedures; Cardiac Tamponade

1964
THE CARDIAC OUTPUT UNDER HALOTHANE ANAESTHESIA WITH INDUCED HYPOTENSION.
    Lancet (London, England), 1964, Dec-12, Volume: 2, Issue:7372

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Spinal; Cardiac Output; Halothane; Heart Function Te

1964
BRAIN STEM ANAESTHESIA--A NEW METHOD OF CONTROLLED HYPOTENSION.
    East African medical journal, 1964, Volume: 41

    Topics: Anesthesia; Anesthesia, General; Biomedical Research; Blood Pressure; Brain Stem; Cisterna Magna; Hu

1964
MEDICAL EMERGENCIES IN THE X-RAY DEPARTMENT PREVENTION AND TREATMENT.
    The British journal of radiology, 1964, Volume: 37

    Topics: Anesthesia; Anesthetics; Anesthetics, Local; Angioedema; Barium Sulfate; Contrast Media; Drug Hypers

1964
INTRAVENOUS REGIONAL ANALGESIA: AN APPRAISAL.
    British medical journal, 1965, Apr-10, Volume: 1, Issue:5440

    Topics: Analgesia; Anesthesia; Anesthesia, Conduction; Anesthesia, Intravenous; Arrhythmias, Cardiac; Electr

1965
THE ACTION OF PRONETHALOL ON SPINAL REFLEXES.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Anesthetics; Anesthetics, Local; Blood Pressure; Electrophysiology; Electroshock; Ethanolamines; Gui

1965
Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors.
    European journal of pharmacology, 2003, Sep-23, Volume: 477, Issue:3

    Topics: alpha-MSH; Animals; Coronary Disease; Cosyntropin; Female; FMRFamide; gamma-MSH; Hypotension; Inject

2003
Dengue myocarditis.
    The Southeast Asian journal of tropical medicine and public health, 2004, Volume: 35, Issue:3

    Topics: Adolescent; Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Epinephrine; Heart Rate; Human

2004
Acute cardiodepressant effects induced by bolus intravenous administration of amiodarone in rabbits.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Output; Female; Hypotension; In

2005
Transient tetraplegia after cervical facet joint injection for chronic neck pain administered without imaging guidance.
    Clinical neurology and neurosurgery, 2006, Volume: 108, Issue:7

    Topics: Adult; Anesthetics, Local; Arteries; Atropine; Bradycardia; Cervical Vertebrae; Chronic Disease; Dia

2006
Involvement of the periaqueductal gray in the hypotensive response evoked by L-glutamate microinjection in the lateral hypothalamus of unanesthetized rats.
    Autonomic neuroscience : basic & clinical, 2005, Oct-30, Volume: 122, Issue:1-2

    Topics: Animals; Anti-Arrhythmia Agents; Cobalt; Glutamic Acid; Hypotension; Hypothalamus; Injections, Intra

2005
Bedside cesarean section due to total spinal block after epidural anesthesia for labor pain.
    International journal of obstetric anesthesia, 2006, Volume: 15, Issue:1

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Cesarean Section; Emergenc

2006
Hemorrhage activates proopiomelanocortin neurons in the rat hypothalamus.
    Brain research, 2006, Jan-27, Volume: 1070, Issue:1

    Topics: Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Bradycardia; Hemorrhage; Hypotension; Hypo

2006
Dose-dependent hypotension from epinephrine, or lidocaine, or both?
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:7

    Topics: Anesthesia, General; Anesthetics, Local; Blood Pressure; Dose-Response Relationship, Drug; Endoscopy

2006
Complications of neuraxial anesthesia in an extreme morbidly obese patient for Cesarean section.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical;

2007
Ultra-low dose combined spinal-epidural anaesthesia.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Combined; Ane

2007
Two cases of bradyarrhythmia and hypotension after extradural injections in dogs.
    Veterinary anaesthesia and analgesia, 2008, Volume: 35, Issue:3

    Topics: Analgesics; Animals; Bradycardia; Bupivacaine; Dog Diseases; Dogs; Female; Hypotension; Injections,

2008
Hypotensive shock during anesthesia for endovascular embolization.
    Journal of neurosurgical anesthesiology, 2008, Volume: 20, Issue:2

    Topics: Adrenergic Agents; Adrenergic Agonists; Aged; Anaphylaxis; Anesthesia; Anti-Arrhythmia Agents; Atria

2008
The preoptic anterior hypothalamic area mediates initiation of the hypotensive response induced by LPS in male rats.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:2

    Topics: Animals; Anterior Hypothalamic Nucleus; Blood Pressure; Hypotension; Lidocaine; Lipopolysaccharides;

2008
[Use of high-dose dexmedetomidine infusion for anesthesia and sedation in a patient for microlaryngeal surgery maintained with spontaneous breathing].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:4

    Topics: Aged; Anesthesia, Intravenous; Anesthesia, Local; Conscious Sedation; Dexmedetomidine; Ephedrine; Fe

2008
Hypotension in anaesthetized patients during aneurysm clipping: not as bad as expected?
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Atracurium; Cohort Studies; Etomidate; Fem

2008
Complete heart block after sublingual nitroglycerin.
    Chest, 1983, Volume: 84, Issue:1

    Topics: Administration, Oral; Electrocardiography; Heart Block; Humans; Hypotension; Lidocaine; Male; Middle

1983
The influence of serum potassium on the cerebral and cardiac toxicity of bupivacaine and lidocaine.
    Anesthesiology, 1984, Volume: 61, Issue:2

    Topics: Animals; Bupivacaine; Cardiac Output; Dogs; Electrocardiography; Electroencephalography; Female; Hea

1984
[Effectiveness and tolerance of "Lignocainum hydrochloricum" in the treatment of arrhythmia in ischemic heart disease].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1983, Nov-15, Volume: 36, Issue:22

    Topics: Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Humans; Hypotension; Lidocaine; Middle Aged; Ti

1983
Control of postcarotid endarterectomy hypotension with baroreceptor blockade.
    American journal of surgery, 1984, Volume: 147, Issue:6

    Topics: Blood Pressure; Carotid Arteries; Carotid Sinus; Endarterectomy; Female; Humans; Hypotension; Lidoca

1984
[Pharmacological protection of the kidneys from ischemic damage. The effectiveness of anti-ischemia protection of the kidneys in simulating the terminal state in the donors].
    Vestnik Akademii meditsinskikh nauk SSSR, 1982, Issue:9

    Topics: Animals; Death; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Humans; Hypotension; Isc

1982
Rational treatment of hypotension after carotid endarterectomy by carotid sinus nerve blockade.
    Acta chirurgica Scandinavica. Supplementum, 1980, Volume: 500

    Topics: Carotid Arteries; Carotid Sinus; Endarterectomy; Female; Humans; Hypotension; Lidocaine; Male; Nerve

1980
Cardiac drug overdose.
    American family physician, 1982, Volume: 25, Issue:1

    Topics: Arrhythmias, Cardiac; Bretylium Compounds; Cardiovascular Agents; Cardiovascular Diseases; Digoxin;

1982
Desipramine cardiac toxicity.
    Minnesota medicine, 1982, Volume: 65, Issue:4

    Topics: Adult; Bretylium Tosylate; Depressive Disorder; Desipramine; Heart Ventricles; Humans; Hypotension;

1982
Excessive serum lidocaine levels during maintenance infusions: mechanisms and prevention.
    American heart journal, 1982, Volume: 104, Issue:2 Pt 1

    Topics: Aged; Arrhythmias, Cardiac; Body Weight; Chromatography, Gas; Disease Susceptibility; Heart Arrest;

1982
Effect of hypotension on liver blood flow and lidocaine disposition.
    The New England journal of medicine, 1982, Sep-30, Volume: 307, Issue:14

    Topics: Aged; Blood Pressure; Female; Half-Life; Humans; Hypotension; Hypotension, Orthostatic; Indocyanine

1982
[Effect of prone position in peridural analgesia during labor].
    Ginecologia y obstetricia de Mexico, 1982, Volume: 50, Issue:299

    Topics: Adolescent; Adult; Anesthesia, Epidural; Blood Pressure; Female; Heart Rate; Humans; Hypotension; La

1982
Maternal, fetal, and neonatal responses after epidural anesthesia with bupivacaine, 2-chloroprocaine, or lidocaine.
    Anesthesia and analgesia, 1982, Volume: 61, Issue:8

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Behavior; Bupi

1982
Toxicity of lidocaine in adult, newborn, and fetal sheep.
    Anesthesiology, 1981, Volume: 55, Issue:1

    Topics: Animals; Animals, Newborn; Cardiovascular System; Central Nervous System; Female; Fetus; Hypotension

1981
Clinical aspects of high spinal anesthesia in urological surgery on 3012 patients.
    Acta anaesthesiologica Belgica, 1980, Volume: 31 Suppl

    Topics: Adult; Aged; Alcoholism; Anesthesia, Spinal; Humans; Hypotension; Lidocaine; Male; Middle Aged; Neur

1980
Gastric dilation during stimulation of cardiac sensory receptors.
    Circulation, 1981, Volume: 63, Issue:4

    Topics: Animals; Bradycardia; Coronary Circulation; Dogs; Female; Heart; Heart Rate; Hypotension; Lidocaine;

1981
Cardiorespiratory effects of intravascular injections of lidocaine in the anesthetized rat. Comparisons between arterial and venous routes of administration.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1995, Volume: 79, Issue:1

    Topics: Animals; Blood Pressure; Bradycardia; Carotid Artery, Internal; Dose-Response Relationship, Drug; He

1995
Uterine and umbilical blood flow velocity during epidural anaesthesia for caesarean section.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:11

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Arteries; Blood Flow Velocity; Cesarean Sectio

1994
[A retrospective analysis of continuous cervical epidural block].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1993, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, Epidural; Bradycardia; Cervical Plexus; Female; Humans; Hypoten

1993
Accidental total spinal block (1)
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:7

    Topics: Accidents; Anesthesia, Epidural; Anesthesia, Obstetrical; Apnea; Cesarean Section; Female; Humans; H

1993
A continuous subdural block.
    British journal of anaesthesia, 1993, Volume: 70, Issue:4

    Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean

1993
Lidocaine attenuates the hypotensive and inflammatory responses to endotoxemia in rabbits.
    Critical care medicine, 1996, Volume: 24, Issue:4

    Topics: Acid-Base Equilibrium; Animals; Drug Evaluation, Preclinical; Endotoxins; Escherichia coli; Female;

1996
Factors associated with hypotension and bradycardia after epidural blockade.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:5

    Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; B

1996
Polymyoclonus resulting from possible accidental subdural injection of local anesthetic.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:3

    Topics: Anesthetics, Local; Humans; Hypotension; Injections, Epidural; Lidocaine; Middle Aged; Myoclonus; St

1997
Hypotension following acute hypovolaemia depends on the caudal midline medulla.
    Neuroreport, 1998, Jun-01, Volume: 9, Issue:8

    Topics: Acute Disease; Anesthetics, Local; Animals; Blood Pressure; Cobalt; Hemorrhage; Hypotension; Lidocai

1998
Safety considerations and fluid resuscitation in liposuction: an analysis of 53 consecutive patients.
    Plastic and reconstructive surgery, 1998, Volume: 102, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics; Female; Humans; Hypotension; Lidocaine; Lipectomy; Male; Middle

1998
Sedation with xylazine and lumbosacral epidural administration of lidocaine and xylazine for umbilical surgery in calves.
    Journal of the American Veterinary Medical Association, 1999, Jan-01, Volume: 214, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia, Epidural; Anesthetics, Local; An

1999
Deaths related to liposuction.
    The New England journal of medicine, 1999, May-13, Volume: 340, Issue:19

    Topics: Adult; Anesthetics, Local; Bradycardia; Cause of Death; Fatal Outcome; Female; Humans; Hypotension;

1999
Permissive hypercapnia during thoracic anaesthesia.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:8

    Topics: Aged; Anesthesia, General; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbon Dioxide; Cardiotonic

1999
Perioperative stroke associated with postoperative epidural analgesia.
    Journal of clinical anesthesia, 2000, Volume: 12, Issue:1

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Arm; Cerebr

2000
Cardiac resuscitation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine in anesthetized dogs.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:1

    Topics: Amides; Anesthetics, Local; Anilides; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Ca

2001
Evidence that hemorrhagic hypotension is mediated by the ventrolateral periaqueductal gray region.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:3

    Topics: Animals; Blood Pressure; Cobalt; Heart Rate; Hemorrhage; Hypotension; Lidocaine; Male; Microinjectio

2001
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs.
    The American journal of cardiology, 1976, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovasc

1976
[Sensitization of bradycardia during final hypotension induced by serotonin in rats: effect of lidocaine].
    Archives internationales de physiologie et de biochimie, 1975, Volume: 83, Issue:4

    Topics: Animals; Electrocardiography; Heart; Heart Rate; Hypotension; Lidocaine; Rats; Serotonin; Vagotomy

1975
Long duration subarachnoid anaesthesia with continuous epidural block.
    Praktische Anasthesie, Wiederbelebung und Intensivtherapie, 1979, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, Epidural; Anesthesia, Spinal; Cachexia; Dibucaine; Drug Combina

1979
[Medical support in surgery for pheochromocytoma].
    Helvetica chirurgica acta, 1979, Volume: 46, Issue:3

    Topics: Adrenal Gland Neoplasms; Arrhythmias, Cardiac; Humans; Hypertension; Hypotension; Intraoperative Com

1979
[Sinus arrest after intravenous administration of lidocaine].
    Schweizerische medizinische Wochenschrift, 1979, Dec-22, Volume: 109, Issue:49

    Topics: Atropine; Coronary Disease; Heart Arrest; Humans; Hypotension; Lidocaine; Male; Middle Aged

1979
Letter: effect of epidural analgesia upon fetal and neonatal status.
    American journal of obstetrics and gynecology, 1975, Jul-15, Volume: 122, Issue:6

    Topics: Anesthesia, Epidural; Chloral Hydrate; Female; Fetal Distress; Fetal Heart; Heart Rate; Humans; Hypo

1975
[Peridural anesthesia in obstetrics (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1975, Volume: 179, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Epinephrine; Female; Heart Rate; Human

1975
Vasodepressor reaction induced by inferior vena caval occlusion and isoproterenol.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:6

    Topics: Animals; Atropine; Disease Models, Animal; Drug Administration Routes; Heart Rate; Hypotension; Infu

1992
Incidence of hypotension induced by spinal anesthesia with xylocaine for cesarean section and postpartum tubal ligation.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1992, Volume: 30, Issue:2

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotension; I

1992
Morbidity and mortality with outpatient anesthesia: the Massachusetts experience.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1992, Volume: 50, Issue:7

    Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intraveno

1992
Subarachnoid blockade alters homeostasis by modifying compensatory splanchnic responses to hemorrhagic hypotension.
    Anesthesiology, 1991, Volume: 75, Issue:4

    Topics: Adrenal Medulla; Anesthesia, Spinal; Animals; Dogs; Hemorrhage; Homeostasis; Hypotension; Lidocaine;

1991
The effect of intraoperative retrobulbar block on anesthetic management of enucleation under general anesthesia.
    Nurse anesthesia, 1991, Volume: 2, Issue:1

    Topics: Aged; Anesthesia, Inhalation; Eye Enucleation; Humans; Hypotension; Intraoperative Care; Lidocaine;

1991
Topical lignocaine; toxic lignocaine.
    Anaesthesia, 1990, Volume: 45, Issue:1

    Topics: Adult; Gels; Humans; Hypotension; Intraoperative Complications; Laminectomy; Lidocaine; Lubrication;

1990
Does ritodrine worsen maternal hypotension during epidural anesthesia in gravid ewes?
    Anesthesiology, 1990, Volume: 72, Issue:2

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Animals; Drug Interactions; Female; Heart Rate, Fetal

1990
Brainstem mediation of prefrontal stimulus-produced hypotension.
    Experimental brain research, 1990, Volume: 79, Issue:2

    Topics: Animals; Brain Stem; Electric Stimulation; Frontal Lobe; Hypotension; Hypothalamus; Lidocaine; Male;

1990
Pregnancy does not alter lidocaine toxicity.
    American journal of obstetrics and gynecology, 1990, Volume: 162, Issue:5

    Topics: Animals; Blood Pressure; Bupivacaine; Female; Heart Rate; Hypotension; Lidocaine; Mepivacaine; Pregn

1990
[Epidural anesthesia in pediatrics. Apropos of 30 cases].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1990, Volume: 31, Issue:1

    Topics: Adolescent; Analgesia, Epidural; Anesthesia, Epidural; Bupivacaine; Child; Child, Preschool; Drug Co

1990
Topical lignocaine: toxic lignocaine.
    Anaesthesia, 1990, Volume: 45, Issue:6

    Topics: Administration, Topical; Gels; Humans; Hypotension; Lidocaine; Urethra

1990
Tracheostomy performed under cervical epidural blockade.
    Anesthesiology, 1989, Volume: 71, Issue:1

    Topics: Aged; Anesthesia, Epidural; Humans; Hypotension; Intraoperative Period; Lidocaine; Male; Neck; Pheny

1989
[Suppression of cardiac activity and respiration during conduction anesthesia].
    Vestnik khirurgii imeni I. I. Grekova, 1989, Volume: 142, Issue:5

    Topics: Anesthesia, Conduction; Arteriosclerosis Obliterans; Humans; Hypotension; Leg; Lidocaine; Male; Midd

1989
Ventricular tachycardia and hypotension with amniotic fluid embolism during cesarean section.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Adult; Anesthesia, Obstetrical; Blood Pressure; Bupivacaine; Cesarean Section; Diazepam; Electrocard

1986
Clinical response and total and unbound plasma concentrations after lidocaine overdose.
    Therapeutic drug monitoring, 1988, Volume: 10, Issue:4

    Topics: Aged; Half-Life; Heart Rate; Humans; Hypotension; Immunoassay; Lidocaine; Male; Tremor

1988
[The changes in systemic and hepatic hemodynamics with phenylephrine during the epidural block in dog].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1988, Volume: 26, Issue:6

    Topics: Anesthesia, Epidural; Animals; Dogs; Hemodynamics; Hypotension; Lidocaine; Phenylephrine

1988
Lidocaine skinwheal fails to prevent vasovagal reflex during venipuncture.
    The West Virginia medical journal, 1987, Volume: 83, Issue:6

    Topics: Anesthesia, Local; Bradycardia; Humans; Hypotension; Lidocaine; Male; Middle Aged; Punctures; Reflex

1987
Intravenous lidocaine overdosage in a child.
    Journal of toxicology. Clinical toxicology, 1986, Volume: 24, Issue:1

    Topics: Child; Dopamine; Glucagon; Half-Life; Humans; Hypotension; Isoproterenol; Kinetics; Lidocaine; Liver

1986
Exacerbation of ventricular tachycardia by tocainide.
    Clinical cardiology, 1985, Volume: 8, Issue:1

    Topics: Aged; Electrocardiography; Female; Heart Ventricles; Humans; Hypotension; Lidocaine; Male; Middle Ag

1985
Cardiovascular toxicity of local anesthetics: an alternative hypothesis.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Brain; Bupivacaine; Electric Stimulation

1986
Obstetric consequences of epidural analgesia.
    Lancet (London, England), 1971, Jul-10, Volume: 2, Issue:7715

    Topics: Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; Female; Fetal Death; Humans;

1971
[Complications of regional anaesthesia and their treatment (author's transl)].
    Munchener medizinische Wochenschrift (1950), 1973, Oct-12, Volume: 115, Issue:41

    Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis

1973
Lidocaine as an antiarrhythmic Experience in 68 patients.
    Acta medica Scandinavica, 1969, Volume: 185, Issue:4

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Card

1969
Management of acute myocardial infarction.
    The Journal of the Arkansas Medical Society, 1971, Volume: 68, Issue:3

    Topics: Acute Disease; Arkansas; Arrhythmias, Cardiac; Coronary Care Units; Heart Block; Humans; Hypotension

1971
[Adverse effects of recent ventricular anti-arrhythmia drug].
    La Vie medicale au Canada francais, 1972, Volume: 1, Issue:2

    Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Drug Synergism; Electro

1972
[Intoxication with antiarrythmica (author's transl)].
    Padiatrie und Padologie, 1972, Volume: 7, Issue:1

    Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child, Preschool; Electrocardiography; Human

1972
Side effects of water-soluble contrast media in lumbar myelography.
    Acta radiologica: diagnosis, 1973, Volume: 14, Issue:6

    Topics: Anesthesia, Spinal; Diazepam; Female; Headache; Humans; Hyperesthesia; Hypotension; Iothalamic Acid;

1973
Profound hypotension and bradycardia after a single bolus of lidocaine.
    Journal of electrocardiology, 1974, Volume: 7, Issue:1

    Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Atropine; Bradycardia; Coronary Disease; Humans; Hypote

1974
Observations during anesthesia for cardiac homotransplantation in ten patients.
    Anesthesiology, 1969, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Inhalation; Atropine; Blood Pressure; Bradycardia; Calcium Chloride;

1969
New and interesting aspects of obstetric conduction anesthesia. A. Placental transfer of local anesthetics.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 25

    Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Animals; Fe

1966
Fetal heart rate patterns following epidural anaesthesia and oxytocin infusion during labour.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1972, Volume: 79, Issue:4

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Electrocardiography; Female; Fetal Heart; Heart Rate;

1972
How benign is lidocaine?
    Chest, 1972, Volume: 61, Issue:7

    Topics: Coronary Care Units; Heart Arrest; Humans; Hypotension; Lidocaine; Myocardial Infarction

1972
[Comparison of 2 modern antiarrhythmic drugs: lidocaine and diphenylhydantoin].
    Giornale italiano di cardiologia, 1972, Volume: 2, Issue:4

    Topics: Arrhythmias, Cardiac; Brain; Chronic Disease; Hemodynamics; Humans; Hypotension; Lidocaine; Necrosis

1972
Intracardiac route of the Bezold-Jarisch reflex.
    The American journal of physiology, 1971, Volume: 221, Issue:5

    Topics: Animals; Bradycardia; Coronary Vessels; Dogs; Electrocardiography; Heart; Heart Block; Heart Conduct

1971
Carotid sinus reflex during radical neck dissection.
    Southern medical journal, 1969, Volume: 62, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Atropine; Blood Pressure; Bradycardia; Carotid Sinus; Child; F

1969
The effects of local analgesics on respiration.
    Anaesthesia, 1970, Volume: 25, Issue:2

    Topics: Apnea; Humans; Hypotension; Hypoxia; Lidocaine

1970
Blood gas changes in patients undergoing high spinal nerve block.
    Anaesthesia, 1971, Volume: 26, Issue:1

    Topics: Anesthesia, General; Anesthesia, Spinal; Blood Volume; Carbon Dioxide; Dibucaine; Epinephrine; Femal

1971
Acid-base studies in elective caesarean sections during epidural and general anaesthesia.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Anesthesia, Inhalation; Anesthesia, Obstetri

1971
Lignocaine therapy after acute myocardial infarction.
    British medical journal, 1969, Jan-25, Volume: 1, Issue:5638

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Female; Humans; Hydro

1969
An evaluation of bupivacaine in epidural analgesia for obstetrics.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Delivery, Obstetric; Female; Humans

1969
Paraplegia secondary to hypotension and cardiac arrest in a patient who has had previous thoracic surgery.
    Neurology, 1969, Volume: 19, Issue:9

    Topics: Epinephrine; Heart Arrest; Heart Massage; Humans; Hypotension; Lidocaine; Male; Middle Aged; Paraple

1969
The coronary attack: concepts on its etiology and hemodynamic management.
    American heart journal, 1969, Volume: 78, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Aspartate Aminotransferases; Biophysical Phenomena; Biophysics; Blood Fl

1969
[Incidents and accidents related to the intravenous use of xylocaine for the purpose of general anesthesia, and the method of their prevention and treatment].
    Revista espanola de anestesiologia, 1966, Volume: 13, Issue:3

    Topics: Anesthesia, General; Anesthesia, Intravenous; Humans; Hypotension; Lidocaine; Respiratory Insufficie

1966