lidocaine has been researched along with Hypesthesia in 29 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this prospective, randomized, double-blind study was to compare injection pain and postinjection pain of 2% lidocaine with 1:100,000 epinephrine and 3% mepivacaine using the computer-assisted Wand Plus injection system to administer the palatal-anterior superior alveolar (P-ASA) injection." | 9.11 | Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine. ( Beck, M; Burns, Y; Nusstein, J; Reader, A; Weaver, J, 2004) |
| "The purpose of this prospective, randomized, double-blind study was to compare injection pain and postinjection pain of 2% lidocaine with 1:100,000 epinephrine and 3% mepivacaine using the computer-assisted Wand Plus injection system to administer the palatal-anterior superior alveolar (P-ASA) injection." | 5.11 | Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine. ( Beck, M; Burns, Y; Nusstein, J; Reader, A; Weaver, J, 2004) |
| "05) less painful than either lidocaine hydrochloride or diphenhydramine and equivalent to placebo." | 5.10 | Comparison of effects of lidocaine hydrochloride, buffered lidocaine, diphenhydramine, and normal saline after intradermal injection. ( Chen, E; McSweeney, TD; Reilley, TE; Tibbits, DL; Xia, Y, 2002) |
| "The addition of lidocaine in PCIA was not beneficial to improve the pain during activities and increased the incidence of perioral numbness and dizziness." | 4.31 | Analgesic Effects and Adverse Reactions of Lidocaine for Patient-Controlled Intravenous Analgesia on Patients Undergoing Open Hepatectomy: A Retrospective Analysis. ( Chen, YJ; Li, Q; Li, QJ; Li, TT; Liu, F; Ma, W; Wang, TH; Xiong, LL, 2023) |
| " We report a case in which a patient presenting with chemotherapy-induced peripheral neuropathy received an IV lidocaine infusion over the course of 60 minutes with complete symptomatic pain relief for a prolonged period of 2 weeks." | 3.81 | Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy. ( Chakrabortty, S; Kumar, AJ; Muppuri, R; Papapetrou, P, 2015) |
| "The lip numbness time of lidocaine was 3." | 3.30 | Articaine versus lidocaine inferior alveolar nerve block in posterior mandible implant surgeries: a randomized controlled trial. ( Alpan, AL; Gülnahar, E; Gülnahar, Y, 2023) |
| "Altogether 5 cases of hypesthesia were found in the articaine group, with 4 temporary and 1 with no mention of nerve involved; there was no case of permanent confirmed hypesthesia." | 2.72 | Does the Use of Articaine Increase the Risk of Hypesthesia in Lower Third Molar Surgery? A Systematic Review and Meta-Analysis. ( Andrey da Costa Araújo, F; de Albuquerque Cavalcanti Almeida, R; Faro, TF; Filipe de Carvalho Nogueira, E; José de Holanda Vasconcellos, R, 2021) |
| "Duration of numbness of soft tissues was significantly longer for articaine (3." | 2.72 | Comparison of articaine 4% and lidocaine 2% in paediatric dental patients. ( Amir, E; Ram, D, 2006) |
| "There were no reports of numbness of the tongue, lip, or cheek, neither were there any adverse local reactions in the oral mucosa." | 2.70 | The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing. ( Friskopp, J; Isacsson, G; Nilsson, M, 2001) |
| "Chronic pain is often a symptom after local anaesthetic-induced nerve injury." | 1.36 | Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections. ( Adey-Viscuso, D; Meechan, JG; Renton, T; Yilmaz, Z, 2010) |
| "Six patients developed numbness in the infraorbital region, five of whom recovered within 3 months; the other recovered by 6 months postoperatively." | 1.35 | Blending of the eyelid-cheek junction and removal of protruding fat: an intraoral approach to blepharoplasty of the lower eyelid. ( Bu, R; Liu, C; Liu, H; Peng, C; Zhang, H; Zhu, K, 2009) |
| "The patient experienced profound numbness of the auricle on the ipsilateral side of the injection that lasted for about an hour following unintended injection to the auriculotemporal nerve." | 1.35 | Numbness of the ear following inferior alveolar nerve block: the forgotten complication. ( Chai, WL; Ngeow, WC, 2009) |
| "Examination confirmed numbness and motor impairment of the lateral plantar nerve." | 1.33 | Lateral plantar nerve injury following steroid injection for plantar fasciitis. ( Dalal, R; Reading, J; Snow, DM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 12 (41.38) | 29.6817 |
| 2010's | 7 (24.14) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, F | 1 |
| Xiong, LL | 1 |
| Li, TT | 1 |
| Chen, YJ | 1 |
| Ma, W | 1 |
| Li, QJ | 1 |
| Li, Q | 1 |
| Wang, TH | 1 |
| Gülnahar, Y | 1 |
| Alpan, AL | 1 |
| Gülnahar, E | 1 |
| Filipe de Carvalho Nogueira, E | 1 |
| Andrey da Costa Araújo, F | 1 |
| Faro, TF | 1 |
| de Albuquerque Cavalcanti Almeida, R | 1 |
| José de Holanda Vasconcellos, R | 1 |
| Patil, PM | 1 |
| Papapetrou, P | 1 |
| Kumar, AJ | 1 |
| Muppuri, R | 1 |
| Chakrabortty, S | 1 |
| Zhang, H | 1 |
| Liu, C | 1 |
| Peng, C | 1 |
| Zhu, K | 1 |
| Bu, R | 1 |
| Liu, H | 1 |
| Ngeow, WC | 1 |
| Chai, WL | 1 |
| Chan, CK | 1 |
| Fok, KL | 1 |
| Poon, CM | 1 |
| Gozdemir, M | 1 |
| Muslu, B | 1 |
| Sert, H | 1 |
| Usta, B | 1 |
| Demircioglu, RI | 1 |
| Karatas, OF | 1 |
| Surgit, O | 1 |
| Al-Sandook, T | 1 |
| Al-Saraj, A | 1 |
| Hersh, EV | 1 |
| Lindemeyer, RG | 1 |
| Renton, T | 1 |
| Adey-Viscuso, D | 1 |
| Meechan, JG | 1 |
| Yilmaz, Z | 1 |
| Xia, Y | 1 |
| Chen, E | 1 |
| Tibbits, DL | 1 |
| Reilley, TE | 1 |
| McSweeney, TD | 1 |
| Nusstein, J | 1 |
| Burns, Y | 1 |
| Reader, A | 4 |
| Beck, M | 4 |
| Weaver, J | 1 |
| Walker, M | 1 |
| Drangsholt, M | 1 |
| Czartoski, TJ | 1 |
| Longstreth, WT | 1 |
| Snow, DM | 1 |
| Reading, J | 1 |
| Dalal, R | 1 |
| Wolff, AP | 1 |
| Groen, GJ | 1 |
| Wilder-Smith, OH | 1 |
| Richardson, J | 1 |
| van Egmond, J | 1 |
| Crul, BJ | 1 |
| Ram, D | 1 |
| Amir, E | 1 |
| Dickson, DR | 1 |
| Thornton, DJ | 1 |
| Hampl, KF | 1 |
| Schneider, MC | 1 |
| Ummenhofer, W | 1 |
| Drewe, J | 1 |
| Shetty, V | 1 |
| Gratt, BM | 1 |
| Flack, V | 1 |
| Katsuta, T | 1 |
| Morioka, T | 1 |
| Hasuo, K | 1 |
| Miyahara, S | 1 |
| Fukui, M | 1 |
| Masuda, K | 1 |
| McLean, C | 1 |
| Meryers, WJ | 1 |
| Verdugo, RJ | 1 |
| Ochoa, JL | 1 |
| Reitz, J | 1 |
| Nist, R | 1 |
| Meyers, WJ | 2 |
| Friskopp, J | 1 |
| Nilsson, M | 1 |
| Isacsson, G | 1 |
| Yonchak, T | 1 |
| Spyratos, SA | 1 |
| Roberts, GD | 1 |
| Harris, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phentolamine Mesylate as a Reversal of Local Anesthesics[NCT03740386] | 90 participants (Actual) | Interventional | 2016-01-01 | Completed | |||
| Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?[NCT03443726] | 120 participants (Actual) | Interventional | 2017-06-10 | Completed | |||
| Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573] | Phase 1 | 31 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
| A Prospective, Randomized, Double-blind Study of the Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Inferior Alveolar Nerve Blocks.[NCT01574807] | Phase 4 | 100 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| Inferior Alveolar Nerve Block: a Novel Intraoral Technique Depends on Extraoral Landmarks[NCT04093713] | 65 participants (Anticipated) | Interventional | 2019-09-14 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
An electric pulp tester will be used to test the lower jaw teeth (molars, premolars, and incisors) for anesthesia (numbness) in 4-minute time cycles for 60 minutes. Measurements of less than 80 on the EPT is considered not numb (anesthesia failure). Readings of 80 equate to anesthetic success. (NCT01574807)
Timeframe: 60 minutes per injection sequence.
| Intervention | Participants (Count of Participants) |
|---|---|
| Mepivacaine + Lidocaine | 44 |
| Lidocaine + Lidocaine | 40 |
2 reviews available for lidocaine and Hypesthesia
| Article | Year |
|---|---|
Does the Use of Articaine Increase the Risk of Hypesthesia in Lower Third Molar Surgery? A Systematic Review and Meta-Analysis.
Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Hypesthesia; Lidoca | 2021 |
Phentolamine mesylate for accelerating recovery from lip and tongue anesthesia.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Ane | 2010 |
14 trials available for lidocaine and Hypesthesia
| Article | Year |
|---|---|
Articaine versus lidocaine inferior alveolar nerve block in posterior mandible implant surgeries: a randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Hypesthesia; Lidoca | 2023 |
Flavored anesthetic lozenge versus Xylocaine spray used as topical pharyngeal anesthesia for unsedated esophagogastroduodenoscopy: a randomized placebo-controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Endoscopy, Digestive System; Female; Humans; Hyp | 2010 |
Transient neurological symptoms after spinal anaesthesia with levobupivacaine 5 mg/ml or lidocaine 20 mg/ml.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Me | 2010 |
Comparison of effects of lidocaine hydrochloride, buffered lidocaine, diphenhydramine, and normal saline after intradermal injection.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Female; Hand; | 2002 |
Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Epinephrine; | 2004 |
Do diagnostic segmental nerve root blocks in chronic low back pain patients with radiation to the leg lack distinct sensory effects? A preliminary study.
Topics: Adult; Amides; Anesthetics, Local; Chronic Disease; Electric Stimulation; Epidemiologic Methods; Fem | 2006 |
Comparison of articaine 4% and lidocaine 2% in paediatric dental patients.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Local; Carticaine; Child; Child, Preschool; Cro | 2006 |
Transient neurologic symptoms after spinal anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacain | 1995 |
Thermographic assessment of reversible inferior alveolar nerve deficit.
Topics: Adult; Cranial Nerve Diseases; Face; Humans; Hypesthesia; Image Interpretation, Computer-Assisted; L | 1994 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine | 1993 |
Reversal of hypoaesthesia by nerve block, or placebo: a psychologically mediated sign in chronic pseudoneuropathic pain patients.
Topics: Adult; Causalgia; Diagnosis, Differential; Female; Humans; Hypesthesia; Lidocaine; Male; Middle Aged | 1998 |
Anesthetic efficacy of the intraosseous injection of 0.9 mL of 2% lidocaine (1:100,000 epinephrine) to augment an inferior alveolar nerve block.
Topics: Adolescent; Adult; Alveolar Process; Analysis of Variance; Anesthesia, Dental; Bicuspid; Dental Pulp | 1998 |
The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Dental Scalin | 2001 |
Anesthetic efficacy of unilateral and bilateral inferior alveolar nerve blocks to determine cross innervation in anterior teeth.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Cuspid; Dental Pulp; Epinephrine; Female; Follow-Up S | 2001 |
13 other studies available for lidocaine and Hypesthesia
| Article | Year |
|---|---|
Analgesic Effects and Adverse Reactions of Lidocaine for Patient-Controlled Intravenous Analgesia on Patients Undergoing Open Hepatectomy: A Retrospective Analysis.
Topics: Analgesia, Patient-Controlled; Analgesics; Dizziness; Granisetron; Hepatectomy; Humans; Hypesthesia; | 2023 |
Prolonged peripheral nerve blockade in patients using lithium carbonate.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Local; Antidepressive Agents; Bipolar Disorder; Depr | 2014 |
Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Hypesthesia; Infusions, Intravenous; Lidoca | 2015 |
Blending of the eyelid-cheek junction and removal of protruding fat: an intraoral approach to blepharoplasty of the lower eyelid.
Topics: Adipose Tissue; Adult; Anesthetics, Local; Blepharoplasty; Cheek; Esthetics; Eyelids; Female; Follow | 2009 |
Numbness of the ear following inferior alveolar nerve block: the forgotten complication.
Topics: Adult; Anesthetics, Local; Ear Auricle; Ear Diseases; Female; Humans; Hypesthesia; Lidocaine; Mandib | 2009 |
Ocular complications after inferior alveolar nerve block: a case report.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Blindness; Confusion; Diplopia; Dizziness; Female; Hu | 2010 |
Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Chin; Cranial Nerve Injuries; Female; Gingiva; H | 2010 |
Dental diplopia with transient abducens palsy.
Topics: Abducens Nerve Diseases; Adult; Anesthesia, Dental; Anesthetics, Local; Bicuspid; Diffusion; Diplopi | 2004 |
Lateral plantar nerve injury following steroid injection for plantar fasciitis.
Topics: Adult; Anesthetics, Local; Fasciitis, Plantar; Foot; Heel; Humans; Hypesthesia; Injections; Lidocain | 2005 |
A postoperative cup of tea--the patient's best friend?
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Burns; Carpal | 2007 |
Discrepancy between provocative test and clinical results following endovascular obliteration of spinal arteriovenous malformation.
Topics: Adult; Arteries; Arteriovenous Malformations; Embolization, Therapeutic; Evoked Potentials, Somatose | 1993 |
Intra-arterial injection.
Topics: Anesthetics, Local; Humans; Hypesthesia; Injections, Intra-Arterial; Lidocaine; Mandibular Nerve; Ma | 2002 |
Neurapraxia of the mylohyoid nerve and submental analgesia.
Topics: Chin; Cranial Nerve Injuries; Humans; Hypesthesia; Lidocaine; Mandibular Nerve; Molar; Nerve Block; | 1973 |