lidocaine has been researched along with Hypertrophy in 5 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
Excerpt | Relevance | Reference |
---|---|---|
"Tetracaine 2% solution applied locally is an easy, safe, inexpensive, and effective analgesia for submucosal diathermy for inferior turbinate hypertrophy." | 9.14 | Lidocaine spray versus tetracaine solution for monopolar submucosal diathermy for inferior turbinate hypertrophy. ( Bizaki, A; Bizakis, J; Bourolias, C; Drivas, E; Hajiioannou, J; Kyrmizakis, DE, 2010) |
"Action and percussion myotonia was associated with weakness in these muscles, and EMG showed diffuse myotonic discharges and myopathic features." | 1.31 | Equine muscular dystrophy with myotonia. ( Cipone, M; Di Stasi, V; Gandini, G; Liguori, R; Monari, L; Montagna, P; Riva, R; Strong, PN, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Martellucci, S | 1 |
Pagliuca, G | 1 |
de Vincentiis, M | 1 |
Greco, A | 1 |
Fusconi, M | 1 |
De Virgilio, A | 1 |
Rosato, C | 1 |
Gallo, A | 1 |
Hajiioannou, J | 1 |
Bizaki, A | 1 |
Bourolias, C | 1 |
Kyrmizakis, DE | 1 |
Drivas, E | 1 |
Bizakis, J | 1 |
Moss, JR | 1 |
Cofer, S | 1 |
Hersey, S | 1 |
Goudy, S | 1 |
Werkhaven, J | 1 |
Swanson, E | 1 |
Mantle, C | 1 |
Stowell, N | 1 |
Byrne, D | 1 |
Wang, L | 1 |
Labadie, R | 1 |
Montagna, P | 1 |
Liguori, R | 1 |
Monari, L | 1 |
Strong, PN | 1 |
Riva, R | 1 |
Di Stasi, V | 1 |
Gandini, G | 1 |
Cipone, M | 1 |
Noble, MI | 1 |
Eisele, JR | 1 |
Frankel, HL | 1 |
Else, W | 1 |
Guz, A | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Pediatric Tonsillectomy Pain Reduction Study, a Randomized, Placebo Controlled, Double-Blind Clinical Trial Using Clonidine and Local Anesthetics[NCT00678379] | Phase 3 | 120 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The median number of intravenous fentanyl doses administered in the PACU due to pain (NCT00678379)
Timeframe: in recovery room
Intervention | number of doses (Median) |
---|---|
Normal Saline | 3.0 |
Lidocaine (1%) + Bupivacaine 0.5% | 3 |
Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 3 |
The total number of intravenous fentanyl doses given PACU which will be compared between the three randomized groups (arms) (NCT00678379)
Timeframe: Post-operative thru day 7
Intervention | number of doses (Median) |
---|---|
Normal Saline | 12 |
Lidocaine (1%) + Bupivacaine 0.5% | 12 |
Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 14 |
(NCT00678379)
Timeframe: Day of Surgery
Intervention | minutes (Median) |
---|---|
Normal Saline | 122 |
Lidocaine (1%) + Bupivacaine 0.5% | 111 |
Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 120 |
Visual analog pain scale range is 0-10 with 0=no pain and 10 = worst pain ever (NCT00678379)
Timeframe: in recovery room; post-operative days 1,3,5 & 7
Intervention | pain score (Mean) | ||||
---|---|---|---|---|---|
In recovery room | day 1 | day 3 | day 5 | day 7 | |
Lidocaine (1%) + Bupivacaine 0.5% | 3 | 4 | 2.5 | 2 | 2 |
Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 3 | 5 | 3 | 3 | 2 |
Normal Saline | 3 | 3 | 3 | 3 | 2.5 |
The number and percent of patients whose post-operative diet has to a regular diet on post-operative days 1, 3, 5 & 7 (NCT00678379)
Timeframe: post-operative days 1,3,5 & 7.
Intervention | Participants (Count of Participants) | |||
---|---|---|---|---|
post-op day 1 | post-op day 3 | post op day 5 | post op day 7 | |
Lidocaine (1%) + Bupivacaine 0.5% | 4 | 8 | 18 | 26 |
Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 1 | 12 | 14 | 22 |
Normal Saline | 7 | 18 | 21 | 24 |
The number and percent of patients whose post-operative diet has only advanced to a soft diet on post-operative days 1, 3, 5 & 7 (NCT00678379)
Timeframe: post-operative days 1,3,5 & 7.
Intervention | Participants (Count of Participants) | |||
---|---|---|---|---|
post-op day 1 | post-op day 3 | post op day 5 | post op day 7 | |
Lidocaine (1%) + Bupivacaine 0.5% | 22 | 26 | 17 | 10 |
Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 26 | 18 | 18 | 14 |
Normal Saline | 26 | 18 | 13 | 13 |
The number and percent of patients whose post-operative diet has advanced to liquids only on post-op days 1, 3, 5 & 7 (NCT00678379)
Timeframe: post-operative days 1,3,5 & 7.
Intervention | Participants (Count of Participants) | |||
---|---|---|---|---|
post-op day 1 | post-op day 3 | post op day 5 | post op day 7 | |
Lidocaine (1%) + Bupivacaine 0.5% | 33 | 13 | 10 | 11 |
Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 30 | 23 | 19 | 10 |
Normal Saline | 16 | 8 | 13 | 6 |
3 trials available for lidocaine and Hypertrophy
Article | Year |
---|---|
EMLA(®) cream as local anesthetic for radiofrequency turbinate tissue reduction.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Bone Diseases; Catheter Ablation; Fe | 2014 |
Lidocaine spray versus tetracaine solution for monopolar submucosal diathermy for inferior turbinate hypertrophy.
Topics: Adolescent; Adult; Anesthetics, Local; Electrocoagulation; Female; Humans; Hypertrophy; Lidocaine; M | 2010 |
Comparison of clonidine, local anesthetics, and placebo for pain reduction in pediatric tonsillectomy.
Topics: Adenoids; Adolescent; Age Factors; Analgesics; Anesthetics, Local; Bupivacaine; Child; Child, Presch | 2011 |
2 other studies available for lidocaine and Hypertrophy
Article | Year |
---|---|
Equine muscular dystrophy with myotonia.
Topics: Anesthetics, Local; Animals; Apamin; Atrophy; Electromyography; Hindlimb; Horse Diseases; Horses; Hy | 2001 |
The role of the diaphragm in the sensation of holding the breath.
Topics: Adult; Apnea; Diaphragm; Electromyography; Female; Humans; Hypertrophy; Lidocaine; Male; Muscles; Ne | 1971 |