lidocaine has been researched along with Hypertension, Portal in 2 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In cirrhosis the bioavailability of a flow-dependent drug increases because of both portosystemic shunting and hepatocyte dysfunction." | 5.27 | Disposition of a flow-limited drug (lidocaine) and a metabolic capacity-limited drug (theophylline) in liver cirrhosis. ( Buccino, G; Cocciolo, M; Colli, A; Parravicini, R; Scaltrini, G, 1988) |
| " In cirrhosis the bioavailability of a flow-dependent drug increases because of both portosystemic shunting and hepatocyte dysfunction." | 1.27 | Disposition of a flow-limited drug (lidocaine) and a metabolic capacity-limited drug (theophylline) in liver cirrhosis. ( Buccino, G; Cocciolo, M; Colli, A; Parravicini, R; Scaltrini, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colli, A | 1 |
| Buccino, G | 1 |
| Cocciolo, M | 1 |
| Parravicini, R | 1 |
| Scaltrini, G | 1 |
2 other studies available for lidocaine and Hypertension, Portal
| Article | Year |
|---|---|
Major complications in continuous epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Bradycardia; Female; Hemorrhage; Humans; Hypertension, Portal; Lidocain | 1980 |
Disposition of a flow-limited drug (lidocaine) and a metabolic capacity-limited drug (theophylline) in liver cirrhosis.
Topics: Adult; Aged; Female; Humans; Hypertension, Portal; Lidocaine; Liver Cirrhosis; Male; Metabolic Clear | 1988 |