lidocaine has been researched along with Hyperhidrosis in 23 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Hyperhidrosis: Excessive sweating. In the localized type, the most frequent sites are the palms, soles, axillae, inguinal folds, and the perineal area. Its chief cause is thought to be emotional. Generalized hyperhidrosis may be induced by a hot, humid environment, by fever, or by vigorous exercise.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Botulinum toxin A diluted in lidocaine causes significantly less pain than BTX-A diluted in saline, whereas it is is equally effective and safe as the latter one in treating axillary hyperhidrosis." | 9.16 | Dilution of botulinum toxin A in lidocaine vs. in normal saline for the treatment of primary axillary hyperhidrosis: a double-blind, randomized, comparative preliminary study. ( Güleç, AT, 2012) |
| "To compare the efficacy and tolerance profile of saline-diluted botulinum toxin A and lidocaine-diluted botulinum toxin A in patients with axillary hyperhidrosis." | 9.12 | Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, double-blind study. ( Simonart, T; Vadoud-Seyedi, J, 2007) |
| "We designed the present study to determine whether JetPeel™-3, a medical device used for transdermal delivery of drugs by jet nebulization, could be used to deliver lidocaine prior to the standard multiple BTX-A injections or deliver lidocaine together with BTX-A in order to determine the protocol giving better results in terms of procedure-related pain, sweating, and patient satisfaction in subjects affected by primary axillary, palmar or plantar hyperhidrosis." | 5.19 | A preliminary study of painless and effective transdermal botulinum toxin A delivery by jet nebulization for treatment of primary hyperhidrosis. ( Aspiro, A; Di Cerbo, A; Iannitti, T; Palmieri, B, 2014) |
| "Botulinum toxin A diluted in lidocaine causes significantly less pain than BTX-A diluted in saline, whereas it is is equally effective and safe as the latter one in treating axillary hyperhidrosis." | 5.16 | Dilution of botulinum toxin A in lidocaine vs. in normal saline for the treatment of primary axillary hyperhidrosis: a double-blind, randomized, comparative preliminary study. ( Güleç, AT, 2012) |
| "Our goal is to determine whether infiltration with a short-acting local anaesthetic such as lidocaine before the surgical incision has a pre-emptive effect on postoperative pain intensity and on incidence of paraesthesia in patients undergoing standard thoracoscopic sympathectomy for palmar hyperhidrosis." | 5.14 | Pre-emptive local analgesia in video-assisted thoracic surgery sympathectomy. ( Busiello, L; Fiorelli, A; Laperuta, P; Messina, G; Napolitano, F; Perrone, A; Santini, M; Vicidomini, G, 2010) |
| "To compare the efficacy and tolerance profile of saline-diluted botulinum toxin A and lidocaine-diluted botulinum toxin A in patients with axillary hyperhidrosis." | 5.12 | Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, double-blind study. ( Simonart, T; Vadoud-Seyedi, J, 2007) |
| "A 2% lidocaine solution was infused through the thoracic drains, which were removed soon after surgery." | 1.36 | [Outpatient or short-stay videothoracoscopy-assisted thoracic sympathectomy: anesthesia in 445 cases]. ( Anglada, MT; Callejas, MA; Gomar, C; Pons, M; Tejedor, A, 2010) |
| "Although pain is the major stumbling block deterring patients and physicians from choosing this treatment option, it is not the only one." | 1.35 | What stands in the way of treating palmar hyperhidrosis as effectively as axillary hyperhidrosis with botulinum toxin type A. ( Benohanian, A, 2009) |
| "The use of botulinum toxin for the treatment of palmar hyperhidrosis is limited due to the pain associated with injections of the palm." | 1.35 | The combined use of forced cold air and topical anesthetic cream for analgesia during the treatment of palmar hyperhydrosis with botulinum toxin injections. ( Halem, M; Patel, R; Zaiac, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (39.13) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Lehrer, E | 1 |
| Nogues, A | 1 |
| Jaume, F | 1 |
| Mullol, J | 1 |
| Alobid, I | 1 |
| Fang, CL | 1 |
| Tsai, CB | 1 |
| Chen, MS | 1 |
| Yang, HY | 1 |
| Fang, KJ | 1 |
| Le, ST | 1 |
| Hanson, C | 1 |
| Rajpara, AN | 1 |
| Liu, DY | 1 |
| Aires, DJ | 1 |
| Yang, H | 1 |
| Kang, J | 1 |
| Zhang, S | 1 |
| Peng, K | 1 |
| Deng, B | 1 |
| Cheng, B | 1 |
| Dixit, S | 1 |
| Lowe, P | 1 |
| Fischer, G | 1 |
| Lim, A | 1 |
| Patakfalvi, L | 1 |
| Benohanian, A | 3 |
| Iannitti, T | 1 |
| Palmieri, B | 1 |
| Aspiro, A | 1 |
| Di Cerbo, A | 1 |
| Shi, LL | 1 |
| Sargen, MR | 1 |
| Chen, SC | 1 |
| Arbiser, JL | 1 |
| Pollack, BP | 1 |
| Fiorelli, A | 1 |
| Vicidomini, G | 1 |
| Laperuta, P | 1 |
| Busiello, L | 1 |
| Perrone, A | 1 |
| Napolitano, F | 1 |
| Messina, G | 1 |
| Santini, M | 1 |
| Patel, R | 1 |
| Halem, M | 1 |
| Zaiac, M | 1 |
| Tejedor, A | 1 |
| Anglada, MT | 1 |
| Pons, M | 1 |
| Callejas, MA | 1 |
| Gomar, C | 1 |
| Güleç, AT | 1 |
| Blaheta, HJ | 1 |
| Vollert, B | 1 |
| Zuder, D | 1 |
| Rassner, G | 1 |
| Sevim, S | 1 |
| Dogu, O | 1 |
| Kaleagasi, H | 1 |
| Satoh-Kuriwada, S | 1 |
| Sasano, T | 1 |
| Date, H | 1 |
| Karita, K | 1 |
| Izumi, H | 1 |
| Shoji, N | 1 |
| Hashimoto, K | 1 |
| Ponce-Olivera, RM | 1 |
| Tirado-Sánchez, A | 1 |
| Arellano-Mendoza, MI | 1 |
| León-Dorantes, G | 1 |
| Kassian-Rank, S | 1 |
| Vadoud-Seyedi, J | 1 |
| Simonart, T | 1 |
| Solomon, P | 1 |
| Juhlin, L | 1 |
| Evers, H | 1 |
| Broberg, F | 1 |
| Henriksen, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment Prior to Injection and Biopsy of the Vulva[NCT03444727] | 13 participants (Actual) | Interventional | 2018-02-19 | Terminated (stopped due to Not enough enrollment) | |||
| Randomized, Single Center, Masked Study Comparing the Efficacy of Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment[NCT03799484] | Phase 4 | 14 participants (Actual) | Interventional | 2019-01-04 | Completed | ||
| Is The Pre-Emptive Administration Of Ketamine A Significant Adjunction To Intravenous Morphine Analgesia For Controlling Post-Operative Pain? A Randomized, Double Blind, Placebo Controlled Clinical Trial.[NCT03415191] | 75 participants (Actual) | Interventional | 2012-01-05 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Loss of Botulinum Toxin Type A effect is defined as return of baseline frontalis muscle function (function prior to injection) as indicated by eyebrow excursion measurement within 2 millimeters of baseline value. (NCT03799484)
Timeframe: week 16
| Intervention | weeks (Mean) |
|---|---|
| Topical Anesthesia | 14.2857 |
| Petrolatum | 15.2857 |
(NCT03799484)
Timeframe: week 16
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 8.21 |
| Petrolatum | 8.07 |
Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Baseline
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 10.57 |
| Petrolatum | 10.57 |
Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Week 2
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 3.46 |
| Petrolatum | 3.43 |
Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Week 6
| Intervention | millimeters (Mean) |
|---|---|
| Topical Anesthesia | 5.96 |
| Petrolatum | 5.68 |
Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 16
| Intervention | Participants (Count of Participants) |
|---|---|
| All Participants | 0 |
Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 2
| Intervention | Participants (Count of Participants) |
|---|---|
| All Participants | 3 |
Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 6
| Intervention | Participants (Count of Participants) |
|---|---|
| All Participants | 2 |
A visual analogue scale will be used to assess pain. The scale ranges from 0 (no pain) to 10 (the worse pain possible), with lower scores indicating a better outcome. (NCT03799484)
Timeframe: Immediately after botox injection
| Intervention | units on a scale (Mean) |
|---|---|
| Topical Anesthesia | 2.43 |
| Petrolatum | 3.96 |
7 trials available for lidocaine and Hyperhidrosis
| Article | Year |
|---|---|
Assessment of craniofacial hyperhidrosis and flushing by sphenopalatine blockade - a randomized trial.
Topics: Endoscopy; Face; Humans; Hyperhidrosis; Lidocaine; Quality of Life; Sphenopalatine Ganglion Block | 2020 |
A preliminary study of painless and effective transdermal botulinum toxin A delivery by jet nebulization for treatment of primary hyperhidrosis.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Botulinum Toxins, Type A; Drug Delivery System | 2014 |
Pre-emptive local analgesia in video-assisted thoracic surgery sympathectomy.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Hand; Humans; Hyperhidros | 2010 |
Dilution of botulinum toxin A in lidocaine vs. in normal saline for the treatment of primary axillary hyperhidrosis: a double-blind, randomized, comparative preliminary study.
Topics: Adolescent; Adult; Anesthetics, Local; Axilla; Botulinum Toxins, Type A; Case-Control Studies; Doubl | 2012 |
Botulinum toxin-A therapy for palmar and plantar hyperhidrosis.
Topics: Adolescent; Adult; Anesthetics, Local; Botulinum Toxins, Type A; Female; Foot; Hand; Humans; Hyperhi | 2002 |
Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, double-blind study.
Topics: Adolescent; Adult; Anesthetics, Local; Axilla; Botulinum Toxins, Type A; Double-Blind Method; Drug C | 2007 |
Inhibition of hyperhidrosis by topical application of a local anesthetic composition.
Topics: Administration, Topical; Adolescent; Adult; Axilla; Drug Combinations; Female; Hand; Humans; Hyperhi | 1979 |
16 other studies available for lidocaine and Hyperhidrosis
| Article | Year |
|---|---|
Factors Affecting the Efficacy of Suction Curettage Using an Arthroscopic Shaver for Bromhidrosis.
Topics: Anesthesia, Local; Anesthetics, Local; Axilla; Curettage; Debridement; Epinephrine; Female; Hematoma | 2021 |
A novel anesthetic technique for palmar botulinum toxin injection.
Topics: Anesthesia; Anesthetics, Local; Botulinum Toxins, Type A; Hand; Humans; Hyperhidrosis; Injections; L | 2017 |
CT-Guided Chemical Thoracic Sympathectomy versus Botulinum Toxin Type A Injection for Palmar Hyperhidrosis.
Topics: Acetylcholine Release Inhibitors; Adolescent; Adult; Anesthetics, Local; Botulinum Toxins, Type A; F | 2019 |
Ice anaesthesia in procedural dermatology.
Topics: Adult; Aluminum; Anesthesia, Local; Australia; Botulinum Toxins, Type A; Cryoanesthesia; Dermatology | 2013 |
Needle-free anaesthesia, a promising option for the needle-phobic patient.
Topics: Anesthesia; Anesthetics, Local; Biopsy, Needle; Botulinum Toxins, Type A; Humans; Hyperhidrosis; Inj | 2014 |
Effective local anesthesia for onabotulinumtoxin A injections to treat hyperhidrosis associated with traumatic amputation.
Topics: Acetylcholine Release Inhibitors; Administration, Cutaneous; Amputation Stumps; Amputation, Traumati | 2016 |
What stands in the way of treating palmar hyperhidrosis as effectively as axillary hyperhidrosis with botulinum toxin type A.
Topics: Administration, Cutaneous; Anesthesia, Local; Anesthetics, Local; Antibodies, Bacterial; Axilla; Bot | 2009 |
The combined use of forced cold air and topical anesthetic cream for analgesia during the treatment of palmar hyperhydrosis with botulinum toxin injections.
Topics: Adult; Anesthetics, Local; Botulinum Toxins, Type A; Cold Temperature; Female; Follow-Up Studies; Ha | 2009 |
[Outpatient or short-stay videothoracoscopy-assisted thoracic sympathectomy: anesthesia in 445 cases].
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthesia, Local; Chylothorax; Fema | 2010 |
Intravenous regional anesthesia (Bier's block) for botulinum toxin therapy of palmar hyperhidrosis is safe and effective.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Local; Botulinum Toxins, Type A; Female; Hand; Humans; | 2002 |
Centrally mediated reflex vasodilation in the gingiva induced by painful tooth-pulp stimulation in sympathectomized human subjects.
Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Blood Pressure; Dental Pulp; Electric Stimulation; | 2003 |
Palmar hyperhidrosis. Safety efficacy of two anaesthetic techniques for botulinum toxin therapy.
Topics: Anesthesia, Local; Anesthetics, Local; Autonomic Nerve Block; Botulinum Toxins, Type A; Hand; Humans | 2006 |
Palmar hyperhidrosis. Needle-free anesthesia as an alternative to Bier's block and peripheral nerve blockade for botulinum toxin therapy.
Topics: Anesthesia, Local; Anesthetics, Local; Botulinum Toxins, Type A; Equipment Design; Hand; Humans; Hyp | 2006 |
Modified Bier block anesthetic technique is safe for office use for botulinum a toxin treatment of palmar and plantar hyperhidrosis.
Topics: Anesthesia, Local; Anesthetics, Local; Botulinum Toxins, Type A; Hand; Humans; Hyperhidrosis; Inject | 2007 |
[Percutaneous injection of hot saline into the upper dorsal sympathetic ganglions in the treatment of palmar hyperhydrosis (author's transl)].
Topics: Ganglia, Sympathetic; Hand; Humans; Hyperhidrosis; Injections; Lidocaine; Sodium Chloride | 1979 |
Local nervous mechanism in regulation of blood flow in human subcutaneous tissue.
Topics: Adipose Tissue; Autonomic Nerve Block; Blood Pressure; Humans; Hyperhidrosis; Lidocaine; Phentolamin | 1976 |