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lidocaine and Hypercapnia

lidocaine has been researched along with Hypercapnia in 20 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
" We measured mean arterial blood pressure (MAP), heart rate (HR), renal sympathetic nerve activity (RSNA), and phrenic nerve activity (PNA) before and after blocking neurotransmission within the PVN by bilateral microinjection of 2% lidocaine (100 nl) during specific stimulation of peripheral chemoreceptors by potassium cyanide (KCN, 75 microg/kg iv, bolus dose) or stimulation of central chemoreceptors with hypercapnia (10% CO(2))."3.73Differential role of the paraventricular nucleus of the hypothalamus in modulating the sympathoexcitatory component of peripheral and central chemoreflexes. ( Patel, KP; Reddy, MK; Schultz, HD, 2005)
" During anaesthesia, all 10 patients required inotropic support to prevent hypotension, 4 patients required tracheal gas insufflation of oxygen to the operated lung to avoid hypoxaemia and 3 patients required lidocaine to treat ventricular arrhythmia."3.70Permissive hypercapnia during thoracic anaesthesia. ( Innami, Y; Kotake, Y; Morisaki, H; Serita, R; Takeda, J, 1999)
"Ventricular fibrillation was then electrically induced and maintained in arrest for 5 mins (n = 12) or 15 mins (n = 20)."1.29Sodium bicarbonate may improve outcome in dogs with brief or prolonged cardiac arrest. ( Bircher, NG; Radovsky, A; Safar, P; Vukmir, RB, 1995)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's6 (30.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reddy, MK1
Patel, KP1
Schultz, HD1
Vukmir, RB1
Bircher, NG1
Radovsky, A1
Safar, P1
Dreshaj, IA1
Haxhiu, MA1
Martin, RJ1
Brinkmann, A1
Calzia, E1
Träger, K1
Radermacher, P1
Morisaki, H1
Serita, R1
Innami, Y1
Kotake, Y1
Takeda, J1
Oyamada, Y1
Andrzejewski, M1
Mückenhoff, K1
Scheid, P1
Ballantyne, D1
Naskret, M1
Płatkiewicz, M1
Billert, H1
Drobnik, L1
Dyderski, S1
Delpierre, S1
Guillot, C1
Fornaris, M1
Gao, CR1
Marleau, S1
Ong, H1
Gariépy, L1
du Souich, P1
Takasaki, M1
Shindoh, C1
Hida, W1
Kikuchi, Y1
Chonan, T1
Inoue, H1
Takishima, T1
Sullivan, TY1
DeWeese, EL1
Fennerty, AG1
Banks, J1
Bevan, C1
Smith, AP1
Easton, PA1
Jadue, C1
Arnup, ME1
Meatherall, RC1
Anthonisen, NR1
Polu, JM1
Sadoul, P1
Jenkins, AV1
Sammons, HG1
Fukuda, H1
Kirchner, JA1
Mckenna, G1
Engle, RP1
Brooks, H1
Dalen, J1
Guz, A1
Noble, MI1
Widdicombe, JG1
Trenchard, D1
Mushin, WW1

Reviews

2 reviews available for lidocaine and Hypercapnia

ArticleYear
Monitoring the hepato-splanchnic region in the critically ill patient. Measurement techniques and clinical relevance.
    Intensive care medicine, 1998, Volume: 24, Issue:6

    Topics: Anesthetics, Local; Carbon Dioxide; Cell Hypoxia; Critical Care; Digestive System Diseases; Gastric

1998
[Medical treatment of arrhythmia during acute respiratory insufficiency].
    Revue medicale de la Suisse romande, 1971, Volume: 91, Issue:11

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Catecholamines; Electric Stimulation; Electrocard

1971

Trials

2 trials available for lidocaine and Hypercapnia

ArticleYear
Ventilation and ventilatory response to carbon dioxide during caudal anaesthesia with lidocaine or bupivacaine in sedated children.
    Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:3

    Topics: Anesthesia, Caudal; Anesthesia, Epidural; Bupivacaine; Child, Preschool; Humans; Hypercapnia; Lidoca

1988
Role of airway receptors in the breathing pattern of patients with chronic obstructive lung disease.
    Thorax, 1985, Volume: 40, Issue:4

    Topics: Aged; Female; Humans; Hypercapnia; Lidocaine; Lung Diseases, Obstructive; Male; Middle Aged; Pulmona

1985

Other Studies

16 other studies available for lidocaine and Hypercapnia

ArticleYear
Differential role of the paraventricular nucleus of the hypothalamus in modulating the sympathoexcitatory component of peripheral and central chemoreflexes.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 289, Issue:3

    Topics: Anesthetics, Local; Animals; Bicuculline; Carotid Body; Chemoreceptor Cells; Denervation; GABA Agoni

2005
Sodium bicarbonate may improve outcome in dogs with brief or prolonged cardiac arrest.
    Critical care medicine, 1995, Volume: 23, Issue:3

    Topics: Acidosis; Animals; Atropine; Blood Circulation; Dogs; Epinephrine; Heart Arrest; Hemodynamics; Hydro

1995
Role of the medullary raphe nuclei in the respiratory response to CO2.
    Respiration physiology, 1998, Volume: 111, Issue:1

    Topics: Animals; Animals, Newborn; Carbon Dioxide; Electrophysiology; Female; Hypercapnia; Hypoglossal Nerve

1998
Permissive hypercapnia during thoracic anaesthesia.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:8

    Topics: Aged; Anesthesia, General; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbon Dioxide; Cardiotonic

1999
Locus coeruleus neurones in vitro: pH-sensitive oscillations of membrane potential in an electrically coupled network.
    Respiration physiology, 1999, Dec-01, Volume: 118, Issue:2-3

    Topics: Acidosis; Animals; Cadmium; Calcium; Cells, Cultured; Culture Media; Hydrogen-Ion Concentration; Hyp

1999
The influence of lidocaine on the permeability of the blood-cerebrospinal fluid barrier in experimental acute hypercapnia in the rabbit.
    Acta neurobiologiae experimentalis, 2001, Volume: 61, Issue:2

    Topics: Acute Disease; Anesthetics, Local; Animals; Anti-Bacterial Agents; Blood Pressure; Blood-Brain Barri

2001
Interaction between vagal and chemoreceptors afferents in ventilatory response to transient hypercapnia (awake rabbits).
    Archives internationales de physiologie et de biochimie, 1978, Volume: 86, Issue:1

    Topics: Afferent Pathways; Animals; Carbon Dioxide; Chemoreceptor Cells; Hypercapnia; Lidocaine; Rabbits; Re

1978
[Cerebral protection in neurosurgical anesthesia].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1991, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Brain Ischemia; Brain Neoplasms; Ce

1991
Lidocaine and indocyanine green kinetics: effect of hypoxemia and/or hypercapnia.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1

    Topics: Animals; Arteries; Carbon Dioxide; Hydrogen-Ion Concentration; Hypercapnia; Hypoxia; Indocyanine Gre

1987
Effects of airway anesthesia on ventilatory responses to graded dead spaces and CO2.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:5

    Topics: Administration, Inhalation; Adult; Chemoreceptor Cells; Humans; Hypercapnia; Lidocaine; Oxygen; Resp

1988
Lack of effect of airway anesthesia on hypoxic ventilation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:5

    Topics: Adult; Airway Resistance; Anesthesia, Local; Forced Expiratory Flow Rates; Forced Expiratory Volume;

1985
Effects of upper or lower airway anesthesia on hypercapnic ventilation in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 59, Issue:4

    Topics: Adult; Aerosols; Anesthesia, Local; Female; Humans; Hypercapnia; Lidocaine; Male; Nerve Block; Phary

1985
Carbon dioxide elimination during bronchoscopy. A comparison of two alternative general anaesthetic techniques.
    British journal of anaesthesia, 1968, Volume: 40, Issue:7

    Topics: Analysis of Variance; Anesthesia, General; Apnea; Arrhythmias, Cardiac; Blood Specimen Collection; B

1968
Changes in the respiratory activity of the cricothyroid muscle with intrathoracic interruption of the vagus nerve.
    The Annals of otology, rhinology, and laryngology, 1972, Volume: 81, Issue:4

    Topics: Animals; Cats; Electromyography; Glottis; Humans; Hypercapnia; Intercostal Muscles; Larynx; Lidocain

1972
Cardiac arrhythmias during electroshock therapy: significance, prevention, and treatment.
    The American journal of psychiatry, 1970, Volume: 127, Issue:4

    Topics: Acidosis, Respiratory; Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Coronary Disease; Electrocard

1970
The effect of bilateral block of vagus and glossopharyngeal nerves on the ventilatory response to CO2 of conscious man.
    Respiration physiology, 1966, Volume: 1, Issue:2

    Topics: Adult; Carbon Dioxide; Glossopharyngeal Nerve; Humans; Hypercapnia; Lidocaine; Male; Respiration; Va

1966