Page last updated: 2024-10-28

lidocaine and Hepatitis

lidocaine has been researched along with Hepatitis in 11 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Liver cirrhosis was produced in rats by intra-abdominal injection of thioacetamide."7.71Reassessment of monoethylglycinexylidide as preoperative liver function test in a rat model of liver cirrhosis and man. ( Ishii, T; Kaneko, H; Katagiri, M; Maeda, T; Otsuka, Y; Shiba, T; Takagi, S; Tamura, A; Tsuchiya, M, 2001)
"Liver cirrhosis was produced in rats by intra-abdominal injection of thioacetamide."3.71Reassessment of monoethylglycinexylidide as preoperative liver function test in a rat model of liver cirrhosis and man. ( Ishii, T; Kaneko, H; Katagiri, M; Maeda, T; Otsuka, Y; Shiba, T; Takagi, S; Tamura, A; Tsuchiya, M, 2001)
"Patients with acute hepatitis and patients with compensated or decompensated cirrhosis of the liver have a decreased plasma clearance of hexobarbital."3.66[Drug metabolism in patients with liver disease (author's transl)]. ( Epping, J; Fuchshofen-Röckel, M; Heusler, H; Richter, E; Zilly, W, 1980)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuchshofen, M1
Heusler, H2
Lutz, B1
Mora, E1
Richter, E2
Epping, J1
Fuchshofen-Röckel, M1
Zilly, W1
Ziebell, J1
Shaw-Stiffel, TA1
Shiffman, ML2
Luketic, VA2
Sanyal, AJ2
Duckworth, PF1
Purdum, PP2
Contos, MJ1
Mills, AS1
Edinboro, LE1
Poklis, A1
Huang, YS1
Lee, SD1
Deng, JF1
Wu, JC1
Lu, RH1
Lin, YF1
Wang, YJ1
Lo, KJ1
Fisher, RA1
Posner, MP1
Giannini, E1
Botta, F1
Romagnoli, P1
Testa, R1
Ol'rikh, M1
Kukes, VG1
Igonin, AA1
Kaneko, H1
Otsuka, Y1
Katagiri, M1
Maeda, T1
Tsuchiya, M1
Tamura, A1
Ishii, T1
Takagi, S1
Shiba, T1
Villeneuve, JP1
Thibeault, MJ1
Ampelas, M1
Fortunet-Fouin, H1
LaMarre, L1
Côté, J1
Pomier-Layrargues, G1
Huet, PM1
Adjepon-Yamoah, KK1
Nimmo, J1
Prescott, LF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Development of a Breath Test for Monitoring Liver Metabolic Function in Patients With Chronic Liver Disease and Cirrhosis[NCT00244569]Phase 3120 participants (Anticipated)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lidocaine and Hepatitis

ArticleYear
Measuring lidocaine metabolite--monoethylglycinexylidide as a quantitative index of hepatic function in adults with chronic hepatitis and cirrhosis.
    Journal of hepatology, 1993, Volume: 19, Issue:1

    Topics: Adult; Chronic Disease; Female; Follow-Up Studies; Galactose; Hepatitis; Humans; Indocyanine Green;

1993

Other Studies

10 other studies available for lidocaine and Hepatitis

ArticleYear
[Lidocain clearance after oral and intravenous application in rats with low grade ANIT-cholestasis and galactosamine-induced hepatitis (author's transl)].
    Zeitschrift fur Gastroenterologie, 1980, Volume: 18, Issue:8

    Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Biological Availability; Chemical and Drug

1980
[Drug metabolism in patients with liver disease (author's transl)].
    Leber, Magen, Darm, 1980, Volume: 10, Issue:5

    Topics: Acute Disease; Adult; Antipyrine; Biological Availability; Biotransformation; Cholestasis; Female; H

1980
Quantitative liver testing with MEG-X: more optimism?
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:6

    Topics: Autoimmune Diseases; Biopsy; Hepatitis; Hepatitis C; Lidocaine; Liver; Reproducibility of Results

1995
Hepatic lidocaine metabolism and liver histology in patients with chronic hepatitis and cirrhosis.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Chronic Disease; Female; Hepatitis; Humans; Lidocaine; Liver; Liv

1994
Hepatic lidocaine metabolism is useful in the selection of patients in need of liver transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Hepatitis; Humans; Lidocaine; Liver; Liver Cirrhosis; Liver Diseases; Liver Transplantation

1993
Oral or intravenous lidocaine administration to perform megx test?
    Digestive diseases and sciences, 2000, Volume: 45, Issue:5

    Topics: Administration, Oral; Diagnosis, Differential; Hepatitis; Humans; Infusions, Intravenous; Lidocaine;

2000
[Role of lidocaine metabolism studies in the diagnosis of liver diseases].
    Klinicheskaia laboratornaia diagnostika, 2000, Issue:7

    Topics: Adult; Animals; Clinical Enzyme Tests; Critical Care; Diagnosis, Differential; Dogs; Female; Hepatit

2000
Reassessment of monoethylglycinexylidide as preoperative liver function test in a rat model of liver cirrhosis and man.
    Clinical and experimental medicine, 2001, Volume: 1, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Animal; Hepat

2001
Drug disposition in patients with HBsAg-positive chronic liver disease.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:7

    Topics: Adult; Aminopyrine; Antipyrine; Female; Hepatitis; Hepatitis B Surface Antigens; Hepatitis, Chronic;

1987
Gross impairment of hepatic drug metabolism in a patient with chronic liver disease.
    British medical journal, 1974, Nov-16, Volume: 4, Issue:5941

    Topics: Adult; Antipyrine; Biotransformation; Chronic Disease; Female; Half-Life; Hepatitis; Humans; Jaundic

1974