lidocaine has been researched along with Hemorrhagic Shock in 33 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adenosine, lidocaine, and magnesium, as administered in this study, are inferior to current Hextend-based resuscitation for survival from prolonged hemorrhagic shock in this model." | 7.91 | Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock. ( Cardin, S; Fryer, DM; Glaser, JJ; How, RA; Morgan, CG; Ozuna, KM; Sams, VG; Schaub, LJ, 2019) |
| "5% NaCl with adenosine, lidocaine, and magnesium (ALM) on hemodynamics and mortality in a rat model of severe hemorrhagic shock." | 7.77 | Ultra-small intravenous bolus of 7.5% NaCl/Mg²⁺ with adenosine and lidocaine improves early resuscitation outcome in the rat after severe hemorrhagic shock in vivo. ( Dobson, GP; Letson, HL, 2011) |
| "To study the protective effect of lidocaine against lung injury after hemorrhagic shock in rabbits." | 7.74 | [Protective effects of lidocaine against lung injury after hemorrhagic shock in rabbits]. ( Gu, MN; Lin, CS; Liu, YY; Ruan, LY, 2007) |
| " Use of deferoxamine, an iron chelator and oxygen-free radical scavenger, and hespan (hydroxyethyl starch), a colloid plasma expander, was evaluated in a rat hemorrhagic shock model." | 7.71 | Deferoxamine and hespan complex as a resuscitative adjuvant in hemorrhagic shock rat model. ( Ali, MA; Chang, YJ; Rana, MW; Shapiro, MJ; Taylor, WH, 2002) |
| "Pharmacokinetics of methylprednisolone succinate and methylprednisolone following methylprednisolone sodium succinate administration were studied in five dogs under normal conditions and then during a severe hemorrhagic shock." | 7.67 | Pharmacokinetics of methylprednisolone succinate, methylprednisolone, and lidocaine in the normal dog and during hemorrhagic shock. ( Alvinerie, M; Autefage, A; Oukessou, M; Toutain, PL, 1987) |
| "The hemodynamic and ultrastructural effects of lidocaine HCl pretreatment were assessed on anesthetized rats subjected to acute hemorrhagic shock." | 7.67 | Effect of lidocaine pretreatment on acute hemorrhagic shock in the anesthetized rat. ( Keith, JC, 1986) |
| "Adenosine-lidocaine-magnesium (ALM) mixture is a cardioplegic agent that improves survivability undisputedly in rodents, but not swine, models of hemorrhagic shock." | 5.41 | Mechanistic considerations for adenosine-lidocaine-magnesium (ALM) in controlling coagulopathy. ( Biros, E; Birosova, E; Moran, CS, 2023) |
| " This suggests that the dosage of endotracheal medication may need to be adjusted for various clinical conditions such as shock." | 5.28 | Plasma lidocaine levels occurring with endotracheal administration during hemorrhagic shock. ( Mace, SE, 1990) |
| " We have reported that the dose of adenosine, lidocaine, and magnesium (ALM) fluid therapy for resuscitation from hemorrhagic shock is nearly 3-times higher for pigs than rats." | 4.31 | Changes in plasma alpha-1 acid glycoprotein following hemorrhagic trauma: Possible role in dose differences of ALM drug therapy in rat and pig resuscitation. ( Dobson, GP; Letson, HL; Morris, JL, 2023) |
| "Adenosine, lidocaine, and magnesium, as administered in this study, are inferior to current Hextend-based resuscitation for survival from prolonged hemorrhagic shock in this model." | 3.91 | Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock. ( Cardin, S; Fryer, DM; Glaser, JJ; How, RA; Morgan, CG; Ozuna, KM; Sams, VG; Schaub, LJ, 2019) |
| "5% NaCl + adenosine, lidocaine, and Mg/adenosine and lidocaine provided superior cardiovascular, acid-base, metabolic, and renal recoveries following severe hemorrhagic shock in the pig compared with 7." | 3.80 | Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation. ( Dobson, GP; Granfeldt, A; Hyldebrandt, JA; Letson, HL; Nielsen, TK; Salcedo, PA; Tønnesen, E; Vinten-Johansen, J; Wang, ER, 2014) |
| "5% NaCl adenocaine (adenosine and lidocaine, adenocaine) and Mg on hypotensive resuscitation and coagulopathy in the rat model of severe hemorrhagic shock." | 3.78 | Reversal of acute coagulopathy during hypotensive resuscitation using small-volume 7.5% NaCl adenocaine and Mg2+ in the rat model of severe hemorrhagic shock. ( Dobson, GP; Letson, HL; Mhango, LP; Pecheniuk, NM, 2012) |
| "To study the protective effect of lidocaine against lung injury after hemorrhagic shock in rabbits." | 3.74 | [Protective effects of lidocaine against lung injury after hemorrhagic shock in rabbits]. ( Gu, MN; Lin, CS; Liu, YY; Ruan, LY, 2007) |
| " Use of deferoxamine, an iron chelator and oxygen-free radical scavenger, and hespan (hydroxyethyl starch), a colloid plasma expander, was evaluated in a rat hemorrhagic shock model." | 3.71 | Deferoxamine and hespan complex as a resuscitative adjuvant in hemorrhagic shock rat model. ( Ali, MA; Chang, YJ; Rana, MW; Shapiro, MJ; Taylor, WH, 2002) |
| "Pharmacokinetics of methylprednisolone succinate and methylprednisolone following methylprednisolone sodium succinate administration were studied in five dogs under normal conditions and then during a severe hemorrhagic shock." | 3.67 | Pharmacokinetics of methylprednisolone succinate, methylprednisolone, and lidocaine in the normal dog and during hemorrhagic shock. ( Alvinerie, M; Autefage, A; Oukessou, M; Toutain, PL, 1987) |
| "The hemodynamic and ultrastructural effects of lidocaine HCl pretreatment were assessed on anesthetized rats subjected to acute hemorrhagic shock." | 3.67 | Effect of lidocaine pretreatment on acute hemorrhagic shock in the anesthetized rat. ( Keith, JC, 1986) |
| "However, studies of hemorrhagic shock in nonpregnant animals may not be applicable to less severe hemorrhage in pregnant animals." | 1.28 | Epidural anesthesia worsens uterine blood flow and fetal oxygenation during hemorrhage in gravid ewes. ( Chatterjee, P; Chestnut, DH; DeBruyn, CS; Sipes, SL; Thompson, CS; Vincent, RD, 1992) |
| "In intact rats subjected to hemorrhagic shock, lidocaine pretreatment also facilitated shock resuscitation and reduced ultrastructural damage." | 1.28 | Gastric and cardiac organoprotection by lidocaine. ( Cho, CH; DeRolf, S; Keith, JC; Misra, HP; Pfeiffer, CJ; Pfeiffer, DC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (27.27) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 12 (36.36) | 24.3611 |
| 2020's | 8 (24.24) | 2.80 |
| Authors | Studies |
|---|---|
| Letson, HL | 10 |
| Biros, E | 3 |
| Morris, JL | 3 |
| Dobson, GP | 12 |
| Franko, JJ | 1 |
| Vu, MM | 1 |
| Parsons, ME | 1 |
| Conner, JR | 1 |
| Lammers, DT | 1 |
| Ieronimakis, N | 1 |
| Reynolds, GD | 1 |
| Eckert, MJ | 1 |
| Bingham, JR | 1 |
| Birosova, E | 1 |
| Moran, CS | 1 |
| Glaser, JJ | 2 |
| Cardin, S | 2 |
| Granfeldt, A | 5 |
| Jensen, TH | 1 |
| Mattson, TH | 1 |
| Conner, J | 1 |
| Lammers, D | 1 |
| Holtestaul, T | 1 |
| Jones, I | 1 |
| Kuckelman, J | 1 |
| Letson, H | 1 |
| Dobson, G | 1 |
| Eckert, M | 1 |
| Bingham, J | 1 |
| How, RA | 1 |
| Schaub, LJ | 1 |
| Fryer, DM | 1 |
| Ozuna, KM | 1 |
| Morgan, CG | 1 |
| Sams, VG | 1 |
| Hyldebrandt, JA | 2 |
| Wang, ER | 1 |
| Salcedo, PA | 1 |
| Nielsen, TK | 3 |
| Tønnesen, E | 3 |
| Vinten-Johansen, J | 2 |
| Hvas, CL | 1 |
| Pecheniuk, NM | 1 |
| Mhango, LP | 1 |
| Rizoli, SB | 1 |
| Nascimento, B | 1 |
| Sølling, C | 1 |
| Frøkiær, J | 1 |
| Wogensen, L | 1 |
| Van Haren, RM | 1 |
| Proctor, KG | 1 |
| GORDH, T | 1 |
| FLINN, RB | 1 |
| Ruan, LY | 1 |
| Lin, CS | 1 |
| Liu, YY | 1 |
| Gu, MN | 1 |
| Kirpatovskiĭ, VI | 1 |
| Onishchenko, NA | 1 |
| Lubiako, AA | 1 |
| Danilov, MA | 1 |
| Bogoiavlenskaia, TA | 1 |
| Rana, MW | 1 |
| Shapiro, MJ | 1 |
| Ali, MA | 1 |
| Chang, YJ | 1 |
| Taylor, WH | 1 |
| Vincent, RD | 1 |
| Chestnut, DH | 1 |
| Sipes, SL | 1 |
| DeBruyn, CS | 1 |
| Chatterjee, P | 1 |
| Thompson, CS | 1 |
| Mace, SE | 1 |
| Pfeiffer, CJ | 1 |
| Keith, JC | 2 |
| Cho, CH | 1 |
| DeRolf, S | 1 |
| Pfeiffer, DC | 1 |
| Misra, HP | 1 |
| Toutain, PL | 1 |
| Autefage, A | 1 |
| Oukessou, M | 1 |
| Alvinerie, M | 1 |
| Altura, BM | 1 |
| Altura, BT | 1 |
| Benowitz, N | 1 |
| Forsyth, RP | 1 |
| Melmon, KL | 1 |
| Rowland, M | 1 |
| Bridenbaugh, LD | 1 |
| Moore, DC | 1 |
3 reviews available for lidocaine and Hemorrhagic Shock
| Article | Year |
|---|---|
Mechanistic considerations for adenosine-lidocaine-magnesium (ALM) in controlling coagulopathy.
Topics: Adenosine; Animals; Disease Models, Animal; Humans; Lidocaine; Magnesium; Shock, Hemorrhagic; Swine | 2023 |
Organ dysfunction following regional and global ischemia/reperfusion. Intervention with postconditioning and adenocaine.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Drug Combinations; Heart Arrest; Humans; Ischemia; Ische | 2012 |
Effects of local anesthetics, antihistamines, and glucocorticoids on peripheral blood flow and vascular smooth muscle.
Topics: Anesthetics, Local; Animals; Blood Vessels; Cats; Diphenhydramine; Dogs; Glucocorticoids; Histamine; | 1974 |
30 other studies available for lidocaine and Hemorrhagic Shock
| Article | Year |
|---|---|
ALM Fluid Therapy Shifts Sympathetic Hyperactivity to Parasympathetic Dominance in the Rat Model of Non-Compressible Hemorrhagic Shock.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Fluid Therapy; Lidocaine; Magnesium; | 2022 |
Adenosine, lidocaine, and magnesium for attenuating ischemia reperfusion injury from resuscitative endovascular balloon occlusion of the aorta in a porcine model.
Topics: Adenosine; Animals; Aorta; Balloon Occlusion; Disease Models, Animal; Endovascular Procedures; Hemor | 2022 |
Changes in plasma alpha-1 acid glycoprotein following hemorrhagic trauma: Possible role in dose differences of ALM drug therapy in rat and pig resuscitation.
Topics: Animals; Female; Hemorrhage; Lidocaine; Male; Orosomucoid; Rats; Rats, Sprague-Dawley; Shock, Hemorr | 2023 |
Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock.
Topics: Adenosine; Animals; Emergency Medical Services; Lidocaine; Magnesium; Military Medicine; Resuscitati | 2020 |
Adenosine, Lidocaine, and Magnesium Support a High Flow, Hypotensive, Vasodilatory State With Improved Oxygen Delivery and Cerebral Protection in a Pig Model of Noncompressible Hemorrhage.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Disease Models, Animal; Drug Administration Schedule; Dr | 2020 |
Far Forward Gaps in Hemorrhagic Shock and Prolonged Field Care: An Update of ALM Fluid Therapy for Field Use.
Topics: Adenosine; Animals; Fluid Therapy; Lidocaine; Magnesium; Resuscitation; Shock, Hemorrhagic; Swine | 2020 |
Combatting ischemia reperfusion injury from resuscitative endovascular balloon occlusion of the aorta using adenosine, lidocaine and magnesium: A pilot study.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Aorta; Balloon Occlusion; Disease Models, Animal; Drug | 2021 |
Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock.
Topics: Adenosine; Animals; Cardioplegic Solutions; Disease Models, Animal; Emergency Medical Services; Lido | 2019 |
Adenosine, lidocaine, and Mg2+ fluid therapy leads to 72-hour survival after hemorrhagic shock: A model for studying differential gene expression and extending biological time.
Topics: Adenosine; Animals; Disease Models, Animal; Fluid Therapy; Gene Expression; Gene Expression Profilin | 2019 |
Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation.
Topics: Adenosine; Animals; Blood Volume; Disease Models, Animal; Drug Therapy, Combination; Female; Fluid T | 2014 |
Pulmonary function after hemorrhagic shock and resuscitation in a porcine model.
Topics: Acute Lung Injury; Adenosine; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Cytokines; Drug Comb | 2014 |
Correction of acute traumatic coagulopathy with small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ occurs within 5 minutes: a ROTEM analysis.
Topics: Adenosine; Animals; Blood Coagulation Disorders; Disease Models, Animal; Hemodynamics; Lidocaine; Ma | 2015 |
Ultra-small intravenous bolus of 7.5% NaCl/Mg²⁺ with adenosine and lidocaine improves early resuscitation outcome in the rat after severe hemorrhagic shock in vivo.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug T | 2011 |
Unexpected 100% survival following 60% blood loss using small-volume 7.5% NaCl with adenocaine and Mg(2+) in the rat model of extreme hemorrhagic shock.
Topics: Adenosine; Animals; Lidocaine; Magnesium; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Resus | 2011 |
Reversal of acute coagulopathy during hypotensive resuscitation using small-volume 7.5% NaCl adenocaine and Mg2+ in the rat model of severe hemorrhagic shock.
Topics: Adenosine; Animals; Blood Coagulation Disorders; Disease Models, Animal; Drug Combinations; Hemodyna | 2012 |
Just another fascinating property of hypertonic solutions or something clinically relevant this time?
Topics: Adenosine; Animals; Blood Coagulation Disorders; Drug Combinations; Lidocaine; Magnesium; Male; Shoc | 2012 |
Adenocaine and Mg(2+) reduce fluid requirement to maintain hypotensive resuscitation and improve cardiac and renal function in a porcine model of severe hemorrhagic shock*.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Female; Fluid Therapy; Heart; Hypoten | 2012 |
Clinically relevant animal models needed to advance state of the art fluid resuscitation*.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Female; Fluid Therapy; Heart; Hypoten | 2012 |
HEART-VOLUME STUDIES III. PHONOCARDIOGRAPHIC AND ELECTROCARDIOGRAPHIC CHANGES DURING DILATATION OF THE HEART IN THE RABBIT.
Topics: Aged; Dilatation; Electrocardiography; Heart; Humans; Hypoxia; Lidocaine; Phonocardiography; Shock; | 1964 |
THE PREVENTION OF ACTIVE TUBULAR NECROSIS IN HEMORRHAGIC SHOCK.
Topics: Dextrans; Kidney Function Tests; Kidney Tubules; Lidocaine; Mannitol; Necrosis; Phenoxybenzamine; Pr | 1964 |
[Protective effects of lidocaine against lung injury after hemorrhagic shock in rabbits].
Topics: Animals; Disease Models, Animal; Lidocaine; Lung; Lung Injury; Malondialdehyde; Rabbits; Shock, Hemo | 2007 |
[Pharmacological protection of the kidneys from ischemic damage. The effectiveness of anti-ischemia protection of the kidneys in simulating the terminal state in the donors].
Topics: Animals; Death; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Humans; Hypotension; Isc | 1982 |
Deferoxamine and hespan complex as a resuscitative adjuvant in hemorrhagic shock rat model.
Topics: Animals; Deferoxamine; Hydroxyethyl Starch Derivatives; Iron Chelating Agents; Isotonic Solutions; L | 2002 |
Epidural anesthesia worsens uterine blood flow and fetal oxygenation during hemorrhage in gravid ewes.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Animals; Bupivacaine; Carbon Dioxide; Epinephrine; Fe | 1992 |
Plasma lidocaine levels occurring with endotracheal administration during hemorrhagic shock.
Topics: Animals; Dogs; Intubation, Intratracheal; Lidocaine; Lung; Shock, Hemorrhagic; Trachea | 1990 |
Gastric and cardiac organoprotection by lidocaine.
Topics: Animals; Dogs; Female; Heart; In Vitro Techniques; Ischemia; Lidocaine; Male; Microscopy, Electron; | 1989 |
Pharmacokinetics of methylprednisolone succinate, methylprednisolone, and lidocaine in the normal dog and during hemorrhagic shock.
Topics: Animals; Biological Availability; Dogs; Kinetics; Lidocaine; Liver Circulation; Metabolic Clearance | 1987 |
Effect of lidocaine pretreatment on acute hemorrhagic shock in the anesthetized rat.
Topics: Animals; Blood Pressure; Coronary Disease; Heart Rate; Hemodynamics; Lidocaine; Male; Microscopy, El | 1986 |
Lidocaine disposition kinetics in monkey and man. II. Effects of hemorrhage and sympathomimetic drug administration.
Topics: Animals; Bone and Bones; Brain; Cardiac Output; Half-Life; Haplorhini; Hematocrit; Hemodynamics; Hum | 1974 |
Local infiltration or peripheral nerve block anesthesia for surgery on the patient in shock.
Topics: Adult; Anesthesia, Conduction; Epinephrine; Female; Humans; Hyaluronoglucosaminidase; Lidocaine; Mal | 1965 |