lidocaine has been researched along with Hematologic Malignancies in 2 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether a difference exists in perceived pain during preprocedure anesthetic injection for bone marrow biopsy between buffered and unbuffered lidocaine, to determine whether pain levels change over time, and to investigate relationships between perceived pain scores and other variables." | 5.14 | Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial. ( Curran, CR; Lamb, T; Ruegg, TA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Zhao, PP | 1 |
| Guan, GT | 1 |
| Ruegg, TA | 1 |
| Curran, CR | 1 |
| Lamb, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Contrast of Buffered Vs. Unbuffered Lidocaine in Bone Marrow Biopsies[NCT00456872] | 49 participants (Actual) | Interventional | 2004-12-31 | Completed | |||
| A Randomized Trial of Buffered vs Nonbuffered Lidocaine With Epinephrine for Cervical Loop Excision[NCT01405768] | Phase 2 | 56 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine Arm | 25 |
| Buffered Lidocaine | 19 |
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of the procedure
| Intervention | units on a scale (Median) |
|---|---|
| Lidocaine Arm | 26 |
| Buffered Lidocaine | 18 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 19 | 19 | 18 |
| Lidocaine Arm | 25 | 27 | 19 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Median) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 18 | 13 | 14 |
| Lidocaine Arm | 26 | 25 | 19 |
1 trial available for lidocaine and Hematologic Malignancies
| Article | Year |
|---|---|
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
1 other study available for lidocaine and Hematologic Malignancies
| Article | Year |
|---|---|
[Analgesic Efficacy of Compound Lidocaine Cream in the Lumbar Puncture of Children with Hematologic Tumor].
Topics: Analgesics; Anesthetics, Local; Child; Hematologic Neoplasms; Humans; Lidocaine; Lidocaine, Prilocai | 2019 |