Page last updated: 2024-10-28

lidocaine and Headache Disorders

lidocaine has been researched along with Headache Disorders in 16 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Headache Disorders: Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Open label and retrospective studies have investigated the use of lidocaine in many headache disorders, primarily via injection or infusion."8.98The Use and Method of Action of Intravenous Lidocaine and Its Metabolite in Headache Disorders. ( Berk, T; Silberstein, SD, 2018)
"Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a primary headache syndrome that has been reported to be resistant to treatment with intravenous lidocaine."7.72SUNCT syndrome responsive to intravenous lidocaine. ( Cohen, AS; Goadsby, PJ; Matharu, MS, 2004)
"Open label and retrospective studies have investigated the use of lidocaine in many headache disorders, primarily via injection or infusion."4.98The Use and Method of Action of Intravenous Lidocaine and Its Metabolite in Headache Disorders. ( Berk, T; Silberstein, SD, 2018)
"This service evaluation reviewed greater occipital nerve injections performed unilaterally with 30 mg 1% lidocaine and 40 mg methylprednisolone, to treat disabling headache disorders in children and adolescents."3.88Treatment of disabling headache with greater occipital nerve injections in a large population of childhood and adolescent patients: a service evaluation. ( Goadsby, PJ; Prabhakar, P; Puledda, F, 2018)
"Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a primary headache syndrome that has been reported to be resistant to treatment with intravenous lidocaine."3.72SUNCT syndrome responsive to intravenous lidocaine. ( Cohen, AS; Goadsby, PJ; Matharu, MS, 2004)
"Lidocaine was associated with significantly higher rates of adverse events compared with placebo and may result in lower rates of patient satisfaction."2.58Intranasal Lidocaine for Acute Management of Primary Headaches: A Systematic Review. ( Dagenais, R; Zed, PJ, 2018)
"In two patients with intractable headache, the daily maximum intensity of headache (graded by 11-point numeric rating scale) was recorded for 7 days postprocedure."1.62Intra-arterial injection of lidocaine into middle meningeal artery to treat intractable headaches and severe migraine. ( Babar, S; French, BR; Gomez, CR; Huang, W; Ishfaq, MF; Lobanova, I; Pfeiffer, K; Qureshi, AI; Siddiq, F, 2021)
" Dosing regimens, volumes of injection, and injection schedules varied greatly."1.36Patterns of use of peripheral nerve blocks and trigger point injections among headache practitioners in the USA: Results of the American Headache Society Interventional Procedure Survey (AHS-IPS). ( Ashkenazi, A; Blumenfeld, A; DePalma, T; Grosberg, B; Lipton, RB; Napchan, U; Narouze, S; Nett, B; Rosenthal, B; Tepper, S, 2010)
"Lidocaine infusion was generally well tolerated with a low incidence of adverse events leading to discontinuation of treatment."1.35Intravenous lidocaine in the treatment of refractory headache: a retrospective case series. ( Abbas, M; Marmura, M; Rosen, N; Silberstein, S, 2009)
"The pathophysiology of many types of chronic headaches is not well understood."1.33Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis? ( Cook, AJ; Hamill-Ruth, RJ; Rowlingson, JC; Yi, X, 2005)
"His headaches fit the IHS criteria for cluster headache but had some irregularities including frequent side shifting of pain, irregular duration and time of onset and the ability of the patient to sit completely still during a headache without any sense of agitation."1.33Non-hypothalamic cluster headache: the role of the greater occipital nerve in cluster headache pathogenesis. ( Rozen, TD, 2005)
"Patients with chronic daily headache with medication overuse are difficult to treat, especially when the doses of analgesia are substantial."1.32Intravenous lignocaine (lidocaine) infusion for the treatment of chronic daily headache with substantial medication overuse. ( Stark, RJ; Williams, DR, 2003)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (56.25)29.6817
2010's5 (31.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Digala, LP1
Lucchese, S1
Qureshi, AI1
Pfeiffer, K1
Babar, S1
Huang, W1
Lobanova, I1
Ishfaq, MF1
French, BR1
Siddiq, F1
Gomez, CR1
Puledda, F1
Goadsby, PJ3
Prabhakar, P1
Berk, T1
Silberstein, SD1
Dagenais, R1
Zed, PJ1
Farmer, RL1
Garg, RK1
Afifi, AM1
de Ru, JA1
Buwalda, J1
Rosen, N1
Marmura, M1
Abbas, M1
Silberstein, S1
Rozen, TD2
Blumenfeld, A1
Ashkenazi, A1
Grosberg, B1
Napchan, U1
Narouze, S1
Nett, B1
DePalma, T1
Rosenthal, B1
Tepper, S1
Lipton, RB1
Linetsky, FS1
Miguel, R1
Torres, F1
Williams, DR1
Stark, RJ1
Matharu, MS1
Cohen, AS1
Shields, KG1
Levy, MJ1
Yi, X1
Cook, AJ1
Hamill-Ruth, RJ1
Rowlingson, JC1

Reviews

4 reviews available for lidocaine and Headache Disorders

ArticleYear
The Use and Method of Action of Intravenous Lidocaine and Its Metabolite in Headache Disorders.
    Headache, 2018, Volume: 58, Issue:5

    Topics: Anesthetics; Headache Disorders; Humans; Lidocaine

2018
Intranasal Lidocaine for Acute Management of Primary Headaches: A Systematic Review.
    Pharmacotherapy, 2018, Volume: 38, Issue:10

    Topics: Administration, Intranasal; Anesthetics, Local; Headache Disorders; Humans; Lidocaine; Patient Satis

2018
Can Functional Nasal Surgery Treat Chronic Headaches? A Systematic Review.
    Plastic and reconstructive surgery, 2018, Volume: 142, Issue:6

    Topics: Anesthetics, Local; Chronic Disease; Endoscopy; Headache Disorders; Humans; Lidocaine; Pain Measurem

2018
Treatment of cervicothoracic pain and cervicogenic headaches with regenerative injection therapy.
    Current pain and headache reports, 2004, Volume: 8, Issue:1

    Topics: Cervical Vertebrae; Clinical Trials as Topic; Collagen; Connective Tissue Diseases; Glucose; Glycero

2004

Other Studies

12 other studies available for lidocaine and Headache Disorders

ArticleYear
IV Lidocaine Infusion Leading to the Toxic Levels in Serum Causing Asystole - A Case Report.
    Headache, 2020, Volume: 60, Issue:1

    Topics: Anesthetics; Depressive Disorder; Drug Interactions; Female; Headache Disorders; Heart Arrest; Human

2020
Intra-arterial injection of lidocaine into middle meningeal artery to treat intractable headaches and severe migraine.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2021, Volume: 31, Issue:6

    Topics: Headache Disorders; Humans; Injections, Intra-Arterial; Lidocaine; Meningeal Arteries; Migraine Diso

2021
Treatment of disabling headache with greater occipital nerve injections in a large population of childhood and adolescent patients: a service evaluation.
    The journal of headache and pain, 2018, Jan-16, Volume: 19, Issue:1

    Topics: Adolescent; Child; Female; Headache Disorders; Headache Disorders, Primary; Humans; Lidocaine; Male;

2018
Botulinum toxin A injection into corrugator muscle for frontally localised chronic daily headache or chronic tension-type headache.
    The Journal of laryngology and otology, 2009, Volume: 123, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Local; Botulinum Toxins, Type A; Facial Muscles; Facial Pain; Female

2009
Intravenous lidocaine in the treatment of refractory headache: a retrospective case series.
    Headache, 2009, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Female; Headache Disorders; Humans; Infusions, Intraven

2009
Intranasal contact point headache: missing the "point" on brain MRI.
    Neurology, 2009, Mar-24, Volume: 72, Issue:12

    Topics: Anesthetics, Local; Female; Headache Disorders; Humans; Lidocaine; Magnetic Resonance Imaging; Male;

2009
Patterns of use of peripheral nerve blocks and trigger point injections among headache practitioners in the USA: Results of the American Headache Society Interventional Procedure Survey (AHS-IPS).
    Headache, 2010, Volume: 50, Issue:6

    Topics: Anesthetics, Local; Bupivacaine; Cross-Sectional Studies; Headache; Headache Disorders; Health Care

2010
Intravenous lignocaine (lidocaine) infusion for the treatment of chronic daily headache with substantial medication overuse.
    Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Female; Headache Disorders; Humans; I

2003
SUNCT syndrome responsive to intravenous lidocaine.
    Cephalalgia : an international journal of headache, 2004, Volume: 24, Issue:11

    Topics: Conjunctiva; Female; Headache Disorders; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Age

2004
Alopecia and cutaneous atrophy after greater occipital nerve infiltration with corticosteroid.
    Neurology, 2004, Dec-14, Volume: 63, Issue:11

    Topics: Adipose Tissue; Adult; Alopecia; Anesthesia, Local; Anesthetics, Local; Atrophy; Female; Headache Di

2004
Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis?
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Plexus; Cervical Vertebrae; Chronic Disease;

2005
Non-hypothalamic cluster headache: the role of the greater occipital nerve in cluster headache pathogenesis.
    The journal of headache and pain, 2005, Volume: 6, Issue:3

    Topics: Afferent Pathways; Anesthetics, Local; Anti-Inflammatory Agents; Anticonvulsants; Circadian Rhythm;

2005