lidocaine has been researched along with Headache, Tension in 9 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study aimed to evaluate the efficacy of local lidocaine injections into the myofascial trigger points (TPs) located at the pericranial muscles in patients with episodic tension-type headache (ETTH)." | 9.17 | Lidocaine injection of pericranial myofascial trigger points in the treatment of frequent episodic tension-type headache. ( Gül, HL; Inan, LE; Karadaş, Ö, 2013) |
| " In this study, the efficacy of local lidocaine application on anxiety and depression and its curative effect in patients with chronic TTH was investigated." | 9.17 | Efficacy of local lidocaine application on anxiety and depression and its curative effect on patients with chronic tension-type headache. ( Inan, LE; Karadaş, Ö; Odabaşi, Z; Ulaş, Ü, 2013) |
| "The present study aimed to evaluate the efficacy of local lidocaine injections into the myofascial trigger points (TPs) located at the pericranial muscles in patients with episodic tension-type headache (ETTH)." | 5.17 | Lidocaine injection of pericranial myofascial trigger points in the treatment of frequent episodic tension-type headache. ( Gül, HL; Inan, LE; Karadaş, Ö, 2013) |
| " In this study, the efficacy of local lidocaine application on anxiety and depression and its curative effect in patients with chronic TTH was investigated." | 5.17 | Efficacy of local lidocaine application on anxiety and depression and its curative effect on patients with chronic tension-type headache. ( Inan, LE; Karadaş, Ö; Odabaşi, Z; Ulaş, Ü, 2013) |
| "Tension-type headache (TTH) is the most common type of primary headache, and trigger point injection (TPI) is frequently used for controlling pain originating from TTHs." | 1.72 | Ultrasound-guided 5-in-1 trigger point injection for treating tension-type headache: A case report. ( Chang, MC; Choo, YJ; Kim, JY, 2022) |
| "Five infusions were given for status migrainosus in three patients, with four of these infusions successfully relieving the headache." | 1.31 | Intravenous lignocaine infusions for severe chronic daily headache. ( Hand, PJ; Stark, RJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JY | 1 |
| Choo, YJ | 1 |
| Chang, MC | 1 |
| Akbas, I | 1 |
| Kocak, AO | 1 |
| Akgol Gur, ST | 1 |
| Oral Ahiskalioglu, E | 1 |
| Dogruyol, S | 1 |
| Dolanbay, T | 1 |
| Demir, M | 1 |
| Cakir, Z | 1 |
| Karadaş, Ö | 3 |
| Gül, HL | 1 |
| Inan, LE | 2 |
| Ulaş, Ü | 1 |
| Odabaşi, Z | 1 |
| Nöbel, M | 1 |
| Feistel, S | 1 |
| Ellrich, J | 1 |
| Messlinger, K | 1 |
| de Ru, JA | 1 |
| Buwalda, J | 1 |
| Babacan, A | 1 |
| Gül, LH | 1 |
| Ipekdal, IH | 1 |
| Türk Börü, U | 1 |
| Northington, JW | 1 |
| Hand, PJ | 1 |
| Stark, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Spinal Mobilization Versus Myofacial Release Techniques on Pain And Disability In Patients With Tension Type Headache[NCT05673330] | 34 participants (Actual) | Interventional | 2022-11-06 | Completed | |||
| Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012] | Phase 4 | 10 participants (Actual) | Interventional | 2017-05-02 | Terminated (stopped due to Poor enrollment.) | ||
| The Efficacy of Intravenous Lidocaine Infusion in Chronic Unilateral Migraine Headache Clinical and Laboratory Assessment .Aprospective Randomized Double Blind Controlled Study[NCT06109389] | Phase 2 | 80 participants (Actual) | Interventional | 2023-10-01 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketorolac | 1 |
| Lidocaine | 0 |
| Dexamethasone | 0 |
The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months
| Intervention | score on a scale (Number) | |||
|---|---|---|---|---|
| Participant Number #3 at Baseline | Participant Number #3 at 3 Months | Participant Number #8 at Baseline | Participant #8 at 3 Months | |
| Ketorolac | 8 | 3 | 5 | 3 |
TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)
| Intervention | score on a scale (Number) | |||
|---|---|---|---|---|
| Participant Number 3 at Baseline | Participant Number 3 at 3 Months | Participant Number 8 at Baseline | Participant Number 8 at 3 Months | |
| Ketorolac | 8 | 3 | 5 | 3 |
4 trials available for lidocaine and Headache, Tension
| Article | Year |
|---|---|
Lidocaine versus dexketoprofen in treatment of tension-type headache: A double-blind randomized controlled trial.
Topics: Adult; Double-Blind Method; Female; Humans; Ketoprofen; Lidocaine; Male; Middle Aged; Prospective St | 2021 |
Lidocaine injection of pericranial myofascial trigger points in the treatment of frequent episodic tension-type headache.
Topics: Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle | 2013 |
Efficacy of local lidocaine application on anxiety and depression and its curative effect on patients with chronic tension-type headache.
Topics: Adult; Anesthetics, Local; Anxiety; Depression; Double-Blind Method; Female; Humans; Injections; Lid | 2013 |
[The role of pericranial muscles in the succesful management of episodic tension type headache].
Topics: Adolescent; Adult; Anesthetics, Local; Facial Muscles; Female; Humans; Injections, Intramuscular; Li | 2012 |
5 other studies available for lidocaine and Headache, Tension
| Article | Year |
|---|---|
Ultrasound-guided 5-in-1 trigger point injection for treating tension-type headache: A case report.
Topics: Adult; Female; Humans; Lidocaine; Pain; Tension-Type Headache; Trigger Points; Ultrasonography, Inte | 2022 |
ATP-sensitive muscle afferents activate spinal trigeminal neurons with meningeal afferent input in rat - pathophysiological implications for tension-type headache.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Dura Mater; Lidocaine; Male; Muscle, Skelet | 2016 |
Botulinum toxin A injection into corrugator muscle for frontally localised chronic daily headache or chronic tension-type headache.
Topics: Adolescent; Adult; Anesthetics, Local; Botulinum Toxins, Type A; Facial Muscles; Facial Pain; Female | 2009 |
Muscle tension headaches.
Topics: Diagnosis, Differential; Humans; Lidocaine; Nerve Block; Stress, Psychological; Tension-Type Headach | 1994 |
Intravenous lignocaine infusions for severe chronic daily headache.
Topics: Adolescent; Adult; Anesthetics, Local; Chronic Disease; Clinical Protocols; Drug Monitoring; Female; | 2000 |