lidocaine has been researched along with HbS Disease in 9 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epidural analgesia with local anesthetics administered alone or in combination with fentanyl effectively and safely treats the pain of sickle cell vaso-occlusive crisis unresponsive to conventional pain management and does so without causing sedation, respiratory depression, or significant limitation on ambulation." | 3.69 | Epidural analgesia in the management of severe vaso-occlusive sickle cell crisis. ( Billett, C; Casella, JF; Dover, G; Tobin, JR; Yaster, M, 1994) |
| "The management of neuropathic pain and pain related to bone vaso-occlusive crises in sickle cell disease remains challenging in children." | 2.87 | Efficacy and Tolerance of Lidocaine 5% Patches in Neuropathic Pain and Pain Related to Vaso-occlusive Sickle Cell Crises in Children: A Prospective Multicenter Clinical Study. ( Arriuberge, C; Chabaud, S; Darnis, S; Launay, V; Marec-Berard, P; Metzger, S; Morelle, M; Roumenoff-Turcant, F; Rousseau, V; Thouvenin, S; Tourniaire, B, 2018) |
| "Pain is one of the most challenging and stressful conditions to patients with sickle cell disease (SCD) and their clinicians." | 1.43 | CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice. ( Chen, Y; DeSimone, J; He, Y; Lu, J; Molokie, RE; Tian, X; Wang, ZJ; Wilkie, DJ; Xiao, C; Yang, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rousseau, V | 2 |
| Morelle, M | 1 |
| Arriuberge, C | 1 |
| Darnis, S | 1 |
| Chabaud, S | 1 |
| Launay, V | 1 |
| Thouvenin, S | 1 |
| Roumenoff-Turcant, F | 1 |
| Metzger, S | 1 |
| Tourniaire, B | 1 |
| Marec-Berard, P | 2 |
| Puri, L | 1 |
| Morgan, KJ | 1 |
| Anghelescu, DL | 1 |
| Rasolofo, J | 1 |
| Poncelet, M | 1 |
| Nguyen, NL | 1 |
| Kome, AM | 1 |
| Lowe, DK | 1 |
| Coyne, P | 1 |
| Hawks, KG | 1 |
| He, Y | 1 |
| Chen, Y | 1 |
| Tian, X | 1 |
| Yang, C | 1 |
| Lu, J | 1 |
| Xiao, C | 1 |
| DeSimone, J | 1 |
| Wilkie, DJ | 1 |
| Molokie, RE | 1 |
| Wang, ZJ | 1 |
| Yaster, M | 1 |
| Tobin, JR | 1 |
| Billett, C | 1 |
| Casella, JF | 1 |
| Dover, G | 1 |
| Gremse, DA | 1 |
| Fillingim, E | 1 |
| Hoff, CJ | 1 |
| Wells, DJ | 1 |
| Boerth, RC | 1 |
| Fleming, SA | 1 |
| Ffoulkes-Crabbe, DJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Trial Evaluating Lidocaine Intravenous in the Emergency Department For Sickle Cell Crisis - RELIEF-SCC[NCT04614610] | Phase 2 | 100 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lidocaine and HbS Disease
| Article | Year |
|---|---|
Intravenous Lidocaine as an Adjuvant for Pain Associated with Sickle Cell Disease.
Topics: Analgesics; Anemia, Sickle Cell; Drug Therapy, Combination; Humans; Infusions, Intravenous; Lidocain | 2015 |
1 trial available for lidocaine and HbS Disease
| Article | Year |
|---|---|
Efficacy and Tolerance of Lidocaine 5% Patches in Neuropathic Pain and Pain Related to Vaso-occlusive Sickle Cell Crises in Children: A Prospective Multicenter Clinical Study.
Topics: Administration, Cutaneous; Adolescent; Adult; Anemia, Sickle Cell; Anesthetics, Local; Child; Female | 2018 |
7 other studies available for lidocaine and HbS Disease
| Article | Year |
|---|---|
Ketamine and lidocaine infusions decrease opioid consumption during vaso-occlusive crisis in adolescents with sickle cell disease.
Topics: Acute Pain; Adolescent; Age Factors; Analgesics, Opioid; Anemia, Sickle Cell; Female; Humans; Infusi | 2019 |
[Analgesic efficacy of topical lidocaine for vaso-occlusive crisis in children with sickle cell disease].
Topics: Administration, Topical; Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Anemia, Sick | 2013 |
CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice.
Topics: Anemia, Sickle Cell; Anesthetics, Local; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein | 2016 |
Epidural analgesia in the management of severe vaso-occlusive sickle cell crisis.
Topics: Analgesia, Epidural; Anemia, Sickle Cell; Child; Emergencies; Female; Fentanyl; Humans; Lidocaine; M | 1994 |
Hepatic function as assessed by lidocaine metabolism in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Case-Control Studies; Child; Child, Preschool; Coloring Agents; Dye Dilu | 1998 |
Safety and usefulness of intravenous regional anaesthesia.
Topics: Anemia, Sickle Cell; Anesthesia, Conduction; Anesthesia, Intravenous; Child; Child, Preschool; Diabe | 1969 |
Haemoglobin levels and anesthesia in a Nigerian casualty department.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Anesthesia, General; Anesthesia, Local; Arteries; Carbon Dio | 1971 |