lidocaine has been researched along with Glioma in 9 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine is well known as a local anesthetic that has been reported to play an antitumor role in numerous cancers, including glioma." | 8.02 | Lidocaine inhibits glioma cell proliferation, migration and invasion by modulating the circEZH2/miR-181b-5p pathway. ( Ding, Y; Li, X; Wen, J; Xiao, Y; Zheng, S, 2021) |
| "Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas." | 7.68 | Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGF: studies on cultured glioma cells. ( Capala, J; Carlsson, J, 1991) |
| "Malignant glioma is the most common type of brain cancer with poor prognosis." | 5.51 | Lidocaine induces protective autophagy in rat C6 glioma cell line. ( Gagat, M; Grzanka, D; Hałas-Wiśniewska, M; Izdebska, M; Klimaszewska-Wiśniewska, A; Zielińska, W, 2019) |
| "Lidocaine is well known as a local anesthetic that has been reported to play an antitumor role in numerous cancers, including glioma." | 4.02 | Lidocaine inhibits glioma cell proliferation, migration and invasion by modulating the circEZH2/miR-181b-5p pathway. ( Ding, Y; Li, X; Wen, J; Xiao, Y; Zheng, S, 2021) |
| "Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas." | 3.68 | Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGF: studies on cultured glioma cells. ( Capala, J; Carlsson, J, 1991) |
| "Malignant glioma is the most common type of brain cancer with poor prognosis." | 1.51 | Lidocaine induces protective autophagy in rat C6 glioma cell line. ( Gagat, M; Grzanka, D; Hałas-Wiśniewska, M; Izdebska, M; Klimaszewska-Wiśniewska, A; Zielińska, W, 2019) |
| "Lidocaine was a powerful inhibitor initially and its potency declined with time." | 1.27 | Induction of intracellular acyl-CoA:cholesterol acyltransferase activity in glioblastoma cells by lidocaine. ( Bressie, S; Jeng, I; Klemm, N; Samson, L, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, J | 1 |
| Li, X | 1 |
| Ding, Y | 1 |
| Zheng, S | 1 |
| Xiao, Y | 1 |
| Izdebska, M | 1 |
| Hałas-Wiśniewska, M | 1 |
| Zielińska, W | 1 |
| Klimaszewska-Wiśniewska, A | 1 |
| Grzanka, D | 1 |
| Gagat, M | 1 |
| Zakir Hossain, SM | 1 |
| Shinohara, H | 1 |
| Kitano, H | 1 |
| Friedman, SJ | 2 |
| Skehan, P | 2 |
| Capala, J | 1 |
| Carlsson, J | 1 |
| Da Silva, VF | 1 |
| Feeley, M | 1 |
| Raaphorst, GP | 1 |
| Jeng, I | 1 |
| Klemm, N | 1 |
| Bressie, S | 1 |
| Samson, L | 1 |
| Tenser, RB | 1 |
| Corbett, JJ | 1 |
9 other studies available for lidocaine and Glioma
| Article | Year |
|---|---|
Lidocaine inhibits glioma cell proliferation, migration and invasion by modulating the circEZH2/miR-181b-5p pathway.
Topics: Anesthetics, Local; Animals; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; | 2021 |
Lidocaine induces protective autophagy in rat C6 glioma cell line.
Topics: Animals; Autophagy; Beclin-1; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Surviv | 2019 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Gl | 2008 |
Membrane-active drugs potentiate the killing of tumor cells by D-glucosamine.
Topics: Anesthetics, Local; Animals; Cell Line; Cell Membrane; Cell Survival; Drug Synergism; Glioma; Glucos | 1980 |
The inhibition of sterol synthesis by anesthetics.
Topics: Acetates; Anesthetics, Local; Animals; Cell Line; Chlorpromazine; Diphenylacetic Acids; Glioma; Halo | 1979 |
Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGF: studies on cultured glioma cells.
Topics: Cells, Cultured; Chloroquine; Epidermal Growth Factor; Glioma; Humans; Iodine Radioisotopes; Lidocai | 1991 |
Hyperthermic potentiation of BCNU toxicity in BCNU-resistant human glioma cells.
Topics: Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Hot Temperatur | 1991 |
Induction of intracellular acyl-CoA:cholesterol acyltransferase activity in glioblastoma cells by lidocaine.
Topics: Anesthetics, Local; Animals; Cell Line; Cholesterol Esters; Enzyme Induction; Glioma; Lidocaine; Neu | 1985 |
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F | 1974 |