Page last updated: 2024-10-28

lidocaine and Glaucoma

lidocaine has been researched along with Glaucoma in 31 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery."9.11Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005)
"The sub-Tenon's anaesthesia group and the lidocaine 2% jelly group did not vary significantly in subjective pain score (18."5.11Prospective study comparing lidocaine 2% jelly versus sub-Tenon's anaesthesia for trabeculectomy surgery. ( Buys, YM; Carrillo, MM; Faingold, D; Trope, GE, 2004)
"To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery."5.11Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005)
"Ten patients received retrobulbar bupivicaine (Marcaine) in conjunction with cyclocryotherapy for medically unresponsive postpenetrating keratoplasty glaucoma and were found to experience significantly longer postoperative pain than 20 patients who recieved lidocaine (Xylocaine) anesthesia."3.65Prolonged pain after cyclocryotherapy performed with retrobulbar bupivicaine hydrochloride anesthesia. ( Abel, R; Kaufman, HE, 1975)
"Intraocular pressure was measured continuously through a cannula in the vitreous body."2.72Episcleral venous pressure response to brain stem stimulation: Effect of topical lidocaine. ( Kiel, JW; Reitsamer, HA; Strohmaier, CA, 2021)
"Pain was scored subjectively by each patient (0-10) during the injection, peroperatively and postoperatively."2.70[Comparison between Greenbaum's parabulbar anesthesia and Ripart's subtenon anesthesia in the anterior segment surgery]. ( Alberti, M; Baltenneck, A; Batisse, JL; de la Marnierre, E; Mage, F, 2002)
"Blindness in glaucoma is the result of death of Retinal Ganglion Cells (RGCs) and their axons."1.48Anesthetic Preconditioning as Endogenous Neuroprotection in Glaucoma. ( Bolton, E; Chou, TH; Musada, GR; Porciatti, V; Romano, GL, 2018)
"To evaluate the feasibility, reliability and analgesia effect of topical anesthesia combined with subconjunctival anesthesia in anti-glaucomatous surgery."1.32The application of topical anesthesia combined with subconjunctival anesthesia for glaucoma surgery. ( Fan, M; Huang, S; Lian, J; Qiu, C; Yu, M, 2003)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19909 (29.03)18.7374
1990's3 (9.68)18.2507
2000's13 (41.94)29.6817
2010's4 (12.90)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Strohmaier, CA1
Kiel, JW1
Reitsamer, HA1
Patel, S1
Kakouri, A1
Chaudhary, S1
Knepper, PA1
Pfahler, NM1
Samples, J1
Giovingo, M1
Theventhiran, A1
Shabsigh, M1
De Moraes, CG1
Cioffi, GA2
Kamel, M1
Blumberg, D1
Al-Aswad, LA1
Chou, TH1
Musada, GR1
Romano, GL1
Bolton, E1
Porciatti, V1
Sarchahi, AA1
Eskandari, M1
Akhtar, N1
Tayyab, A1
Kausar, A1
Jaffar, S1
Zabriskie, NA1
Ahmed, II1
Crandall, AS1
Daines, B1
Burns, TA1
Patel, BC1
Fortune, B1
Cull, G1
Wang, L1
Van Buskirk, EM1
He, J1
Fu, G1
Pablo Júlvez, LE1
Pérez-Oliván, S2
Ferreras Amed, A1
Larrosa Poves, JM1
Gómez Martínez, ML1
Honrubia López, FM1
Lee, JJ1
Moster, MR1
Henderer, JD1
Membreno, JH1
CASTREN, JA1
BARANY, E1
LONG, JC1
Huang, S1
Yu, M1
Lian, J1
Fan, M1
Qiu, C1
Sodhi, PK1
Verma, L1
Ratan, SK1
Carrillo, MM1
Buys, YM1
Faingold, D1
Trope, GE1
Pablo, LE1
Ferreras, A1
Larrosa, JM1
Gómez, ML1
Honrubia, FM1
Rebolleda, G1
Muñoz-Negrete, FJ1
Benatar, J1
Corcostegui, J1
Alonso, N1
Petrou, CP1
Papastefanou, VP1
Panani, E1
Karkanis, G1
Petrou, P1
Koukoulomatis, P1
Parrish, RK1
Spaeth, GL1
Poryzees, EM1
Hargens, CW1
Ghanchi, FD1
Khan, MY1
Anderson, CJ1
Kallio, H1
Paloheimo, M1
Maunuksela, EL1
Kwok, AK1
Young, AL1
Lam, DS1
de la Marnierre, E1
Mage, F1
Alberti, M1
Batisse, JL1
Baltenneck, A1
Abel, R1
Kaufman, HE1
Musini, A1
Fabbri, B1
Bergamaschi, M1
Mandelli, V1
Shanks, RG1
Judit, BS1
Hanisch, J1
Födö, V1
Stocker, FW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Application of Recombinant Human Hyaluronidase is Effective for the Use of Local Blocks for Eyelid Surgery[NCT02059694]0 participants (Actual)InterventionalWithdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lidocaine and Glaucoma

ArticleYear
Episcleral venous pressure response to brain stem stimulation: Effect of topical lidocaine.
    Experimental eye research, 2021, Volume: 212

    Topics: Administration, Topical; Anesthetics, Local; Animals; Brain Stem; Electric Stimulation; Glaucoma; Hu

2021

Trials

10 trials available for lidocaine and Glaucoma

ArticleYear
A comparison of topical and retrobulbar anesthesia for trabeculectomy.
    Journal of glaucoma, 2002, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine;

2002
[Topical versus contact anaesthesia in conventional trabeculectomy. Prospective randomised study].
    Archivos de la Sociedad Espanola de Oftalmologia, 2003, Volume: 78, Issue:5

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Fema

2003
Prospective study comparing lidocaine 2% jelly versus sub-Tenon's anaesthesia for trabeculectomy surgery.
    The British journal of ophthalmology, 2004, Volume: 88, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Female; Glaucoma; Humans; Hypnotics and Sedatives; Lido

2004
Contact-topical plus intracameral lidocaine versus peribulbar anesthesia in combined surgery: a randomized clinical trial.
    Journal of glaucoma, 2004, Volume: 13, Issue:6

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia; Anesthetics, Local; Bupivacaine; Catar

2004
Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage.
    Acta ophthalmologica Scandinavica, 2005, Volume: 83, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Female; Gels; Glauc

2005
Anesthesia for phacotrabeculectomy.
    Ophthalmology, 2008, Volume: 115, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia; Cataract Extraction; Female; Gels; Glaucoma; Humans; Intraopera

2008
Evaluation of local anesthesia agents using a new force-sensitive lid speculum.
    Ophthalmic surgery, 1983, Volume: 14, Issue:7

    Topics: Anesthetics, Local; Bupivacaine; Facial Nerve; Glaucoma; Humans; Lidocaine; Mepivacaine; Random Allo

1983
Sublingual lorazepam as premedication in peribulbar anesthesia.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:10

    Topics: Administration, Sublingual; Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthetics, Loca

1997
Hyaluronidase as an adjuvant in bupivacaine-lidocaine mixture for retrobulbar/peribulbar block.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine;

2000
[Comparison between Greenbaum's parabulbar anesthesia and Ripart's subtenon anesthesia in the anterior segment surgery].
    Journal francais d'ophtalmologie, 2002, Volume: 25, Issue:2

    Topics: Anesthesia, Local; Anesthetics, Local; Anterior Eye Segment; Bupivacaine; Glaucoma; Humans; Lidocain

2002

Other Studies

20 other studies available for lidocaine and Glaucoma

ArticleYear
The effect of various media and probe angles on the power output of the Cyclo G6 Glaucoma Laser System.
    Lasers in medical science, 2021, Volume: 36, Issue:3

    Topics: Culture Media; Electricity; Glaucoma; Humans; Laser Coagulation; Lidocaine; Treatment Outcome

2021
A Comparison of Retrobulbar Versus Topical Anesthesia in Trabeculectomy and Aqueous Shunt Surgery.
    Journal of glaucoma, 2018, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cohort Studies; Eye

2018
Anesthetic Preconditioning as Endogenous Neuroprotection in Glaucoma.
    International journal of molecular sciences, 2018, Jan-13, Volume: 19, Issue:1

    Topics: Anesthetics; Animals; Axonal Transport; Electroretinography; Glaucoma; Intraocular Pressure; Lidocai

2018
Effect of four local anesthetics (tetracaine, proparacaine, lidocaine, and bupivacaine) on intraocular pressure in dogs.
    International ophthalmology, 2019, Volume: 39, Issue:7

    Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Disease Models

2019
Pain management with retrobulbar alcohol injection in absolute glaucoma.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:6

    Topics: Adult; Aged; Anesthetics, Local; Cohort Studies; Ethanol; Eye Pain; Female; Glaucoma; Humans; Inject

2015
Factors affecting the use of multifocal electroretinography to monitor function in a primate model of glaucoma.
    Documenta ophthalmologica. Advances in ophthalmology, 2002, Volume: 105, Issue:2

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Local; Animals; Electroretinography; Glau

2002
[Clinical observation of intrachamberal anesthesia].
    Yan ke xue bao = Eye science, 1998, Volume: 14, Issue:4

    Topics: Administration, Topical; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Anterior Chamber; Catar

1998
Pupil dilation with intracameral 1% lidocaine during glaucoma filtering surgery.
    American journal of ophthalmology, 2003, Volume: 136, Issue:1

    Topics: Anesthesia, Local; Anesthetics, Local; Anterior Chamber; Eye Color; Female; Glaucoma; Humans; Inject

2003
A CLINICAL EVALUATION OF MEPIVACAINE (CARBOCAIN) IN OCULAR SURGERY).
    Acta ophthalmologica, 1963, Volume: 41

    Topics: Cataract Extraction; Corneal Transplantation; Epinephrine; Glaucoma; Humans; Lidocaine; Mepivacaine;

1963
APPLANATION TONOMETRY AND OPHTHALMOSCOPY OF THE VERVET MONKEY (CERCOPITHECUS ETHIOPS) IN PHENCYCLIDINE CATALEPSIA.
    Investigative ophthalmology, 1963, Volume: 2

    Topics: Anesthesia; Anesthesia, General; Anesthetics; Animals; Cercopithecus; Chlorocebus aethiops; Glaucoma

1963
GERIATRIC OPHTHALMIC SURGERY.
    Arizona medicine, 1964, Volume: 21

    Topics: Atropine; Cataract Extraction; Chymotrypsin; Geriatrics; Glaucoma; Humans; Lidocaine; Ophthalmology;

1964
The application of topical anesthesia combined with subconjunctival anesthesia for glaucoma surgery.
    Yan ke xue bao = Eye science, 2003, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthetics, L

2003
Pupil dilatation with intracameral 1% lidocaine during glaucoma filtering surgery.
    American journal of ophthalmology, 2004, Volume: 137, Issue:4

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Glaucoma; Humans; Lidocaine; Pupil; Te

2004
Circumferential perilimbal anesthesia for combined cataract glaucoma surgery.
    Ophthalmic surgery and lasers, 1999, Volume: 30, Issue:3

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Conjunctiva; Female; Follow-Up Studies; Glaucoma; Human

1999
Efficacy of lignocaine gel for outpatient laser treatment in inflamed eyes.
    Eye (London, England), 2001, Volume: 15, Issue:Pt 5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Child; Eye

2001
Prolonged pain after cyclocryotherapy performed with retrobulbar bupivicaine hydrochloride anesthesia.
    Annals of ophthalmology, 1975, Volume: 7, Issue:2

    Topics: Anesthesia, Local; Anesthetics, Local; Anilides; Cryosurgery; Glaucoma; Humans; Intraocular Pressure

1975
Comparison of the effect of propranolol, lignocaine, and other drugs on normal and raised intraocular pressure in man.
    American journal of ophthalmology, 1971, Volume: 72, Issue:4

    Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesthetics, Local; C

1971
[Iatrogenic lesion in ophthalmologic anesthesia].
    Klinische Monatsblatter fur Augenheilkunde, 1972, Volume: 161, Issue:3

    Topics: Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics; Anesthetics, Local; Atropine; Blin

1972
[On trsnsitory amauroses in retrobulbar and stomatologic local antsthesia].
    Klinische Monatsblatter fur Augenheilkunde, 1968, Volume: 153, Issue:2

    Topics: Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Blindness; Female; Glaucoma; Humans; Lidocaine;

1968
Technique of semipenetrating cyclodiathermy puncture.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 74, Issue:6

    Topics: Acetazolamide; Electrocoagulation; Glaucoma; Humans; Lidocaine; Punctures

1965