Page last updated: 2024-10-28

lidocaine and Genetic Predisposition

lidocaine has been researched along with Genetic Predisposition in 6 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"We demonstrate that lidocaine may suppress Brugada syndrome associated with the N406S mutation by preventing the sodium channel from accumulating in the intermediate inactivation state."7.74A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome. ( Ashihara, T; Horie, M; Imoto, K; Ito, M; Itoh, H; Jo, H; Nagaoka, I; Nakazawa, Y; Oka, Y; Sakaguchi, T; Tsuji, K; Yao, T, 2007)
"To determine clinical features, outcome, risk factors for death, and efficacy of IV administration of lidocaine as a prophylactic treatment for ischemic reperfusion injury in gastric dilatation and volvulus (GDV) in dogs."7.74Evaluation of lidocaine treatment and risk factors for death associated with gastric dilatation and volvulus in dogs: 112 cases (1997-2005). ( Bdolah-Abram, T; Bruchim, Y; Buber, T; Epstein, A; Ranen, E; Saragusty, J, 2007)
"We demonstrate that lidocaine may suppress Brugada syndrome associated with the N406S mutation by preventing the sodium channel from accumulating in the intermediate inactivation state."3.74A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome. ( Ashihara, T; Horie, M; Imoto, K; Ito, M; Itoh, H; Jo, H; Nagaoka, I; Nakazawa, Y; Oka, Y; Sakaguchi, T; Tsuji, K; Yao, T, 2007)
"To determine clinical features, outcome, risk factors for death, and efficacy of IV administration of lidocaine as a prophylactic treatment for ischemic reperfusion injury in gastric dilatation and volvulus (GDV) in dogs."3.74Evaluation of lidocaine treatment and risk factors for death associated with gastric dilatation and volvulus in dogs: 112 cases (1997-2005). ( Bdolah-Abram, T; Bruchim, Y; Buber, T; Epstein, A; Ranen, E; Saragusty, J, 2007)
"Chronic postsurgical pain (CPSP) is an important and well recognized cause of much long-term suffering, which in some cases may be preventable and affects many people living with cancer."2.58Chronic postsurgical pain and cancer: the catch of surviving the unsurvivable. ( Bhaskar, A; Humble, SR; Jayaweera, A; Varela, N, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Humble, SR1
Varela, N1
Jayaweera, A1
Bhaskar, A1
Ogawa, R1
Kishi, R1
Takagi, A1
Sakaue, I1
Takahashi, H1
Matsumoto, N1
Masuhara, K1
Nakazawa, K1
Kobayashi, S1
Miyake, F1
Echizen, H1
Itoh, H1
Tsuji, K1
Sakaguchi, T1
Nagaoka, I1
Oka, Y1
Nakazawa, Y1
Yao, T1
Jo, H1
Ashihara, T1
Ito, M1
Horie, M1
Imoto, K1
Buber, T1
Saragusty, J1
Ranen, E1
Epstein, A1
Bdolah-Abram, T1
Bruchim, Y1
Clancy, CE1
Wehrens, XH1
Surber, R1
Hensellek, S1
Prochnau, D1
Werner, GS1
Benndorf, K1
Figulla, HR1
Zimmer, T1

Reviews

1 review available for lidocaine and Genetic Predisposition

ArticleYear
Chronic postsurgical pain and cancer: the catch of surviving the unsurvivable.
    Current opinion in supportive and palliative care, 2018, Volume: 12, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Chronic Pain; Drug Therapy, Combination; Gabapentin; Ge

2018

Other Studies

5 other studies available for lidocaine and Genetic Predisposition

ArticleYear
A novel microsatellite polymorphism of sodium channel beta1-subunit gene (SCN1B) may underlie abnormal cardiac excitation manifested by coved-type ST-elevation compatible with Brugada syndrome in Japanese.
    International journal of clinical pharmacology and therapeutics, 2010, Volume: 48, Issue:2

    Topics: Adult; Age Factors; Aged; Asian People; Brugada Syndrome; Electrocardiography; Female; Genetic Predi

2010
A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome.
    International journal of cardiology, 2007, Oct-18, Volume: 121, Issue:3

    Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Computer Simulation; Genetic Predisposition to Disease; Hu

2007
Evaluation of lidocaine treatment and risk factors for death associated with gastric dilatation and volvulus in dogs: 112 cases (1997-2005).
    Journal of the American Veterinary Medical Association, 2007, May-01, Volume: 230, Issue:9

    Topics: Animals; Breeding; Dog Diseases; Dogs; Female; Gastric Dilatation; Genetic Predisposition to Disease

2007
Mutation-specific effects of lidocaine in Brugada syndrome.
    International journal of cardiology, 2007, Oct-18, Volume: 121, Issue:3

    Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Genetic Predisposition to Disease; Humans; Lidocaine; Musc

2007
Combination of cardiac conduction disease and long QT syndrome caused by mutation T1620K in the cardiac sodium channel.
    Cardiovascular research, 2008, Mar-01, Volume: 77, Issue:4

    Topics: Action Potentials; Adolescent; Adult; Ajmaline; Animals; Anti-Arrhythmia Agents; Bundle-Branch Block

2008