lidocaine has been researched along with Fissure in Ano in 23 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Fissure in Ano: A painful linear tear at the margin of the anus. It appears as a crack or slit in the mucous membrane of the anus and is very painful and difficult to heal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is to compare the ability of three treatments in patients with anal fissure, sphincterotomy, nitroglycerin ointment and combination of gel xylocaine and lactulose." | 9.14 | Prospective clinical trial comparing sphincterotomy, nitroglycerin ointment and xylocaine/lactulose combination for the treatment of anal fissure. ( Basdanis, G; Fahantidis, E; Ioannidis, A; Karamanlis, E; Mekras, A; Michalopoulos, A; Panagiotou, D; Papadopoulos, V, 2010) |
| "Our study clearly demonstrates that the therapeutic use of topical nifedipine and lidocaine ointment should be extended to the conservative treatment of chronic anal fissure." | 9.10 | Topical nifedipine with lidocaine ointment vs. active control for treatment of chronic anal fissure: results of a prospective, randomized, double-blind study. ( Antropoli, C; Antropoli, M; Attena, F; Balzano, A; Bove, A; De Stefano, G; Molino, D; Perrotti, P, 2002) |
| "Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures." | 9.08 | Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997) |
| "We aimed to evaluate efficacy and safety of the use of nifedipine gel with lidocaine in the treatment of acute anal fissures in children by reviewing the cases of 106 children with acute anal fissure treated conservatively by nifedipine gel with lidocaine between the years 2003-2012." | 7.83 | Anal fissure in children: a 10-year clinical experience with nifedipine gel with lidocaine. ( Abu-Kishk, I; Berkovitch, M; Efrati, Y; Klin, B, 2016) |
| "The aim of this study is to compare the ability of three treatments in patients with anal fissure, sphincterotomy, nitroglycerin ointment and combination of gel xylocaine and lactulose." | 5.14 | Prospective clinical trial comparing sphincterotomy, nitroglycerin ointment and xylocaine/lactulose combination for the treatment of anal fissure. ( Basdanis, G; Fahantidis, E; Ioannidis, A; Karamanlis, E; Mekras, A; Michalopoulos, A; Panagiotou, D; Papadopoulos, V, 2010) |
| "Our study clearly demonstrates that the therapeutic use of topical nifedipine and lidocaine ointment should be extended to the conservative treatment of chronic anal fissure." | 5.10 | Topical nifedipine with lidocaine ointment vs. active control for treatment of chronic anal fissure: results of a prospective, randomized, double-blind study. ( Antropoli, C; Antropoli, M; Attena, F; Balzano, A; Bove, A; De Stefano, G; Molino, D; Perrotti, P, 2002) |
| "Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures." | 5.08 | Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997) |
| "We aimed to evaluate efficacy and safety of the use of nifedipine gel with lidocaine in the treatment of acute anal fissures in children by reviewing the cases of 106 children with acute anal fissure treated conservatively by nifedipine gel with lidocaine between the years 2003-2012." | 3.83 | Anal fissure in children: a 10-year clinical experience with nifedipine gel with lidocaine. ( Abu-Kishk, I; Berkovitch, M; Efrati, Y; Klin, B, 2016) |
| "It is a safe and an effective treatment of anal fissure in a South Asian population." | 2.73 | Comparison of topical glyceryl trinitrate with lignocaine ointment for treatment of anal fissure: a randomised controlled trial. ( Ahmad, J; Andrabi, SI; Rathore, MA, 2007) |
| "The comparator could be placebo, nitroglycerin ointment, or lateral internal sphincterotomy, with dosage ranging from 20 IU to 50 IU of botulinum toxin." | 2.48 | Botulinum toxin and anal fissure: efficacy and safety systematic review. ( Yiannakopoulou, E, 2012) |
| "Anal fissure is common and painful disease of anorectum." | 1.46 | Preparation and characterization of textile-based carrier systems for anal fissure treatment. ( Karavana, SY; Önder, T; Rençber, S; Sarıışık, AM; Türkoğlu, GC, 2017) |
| "Chronic anal fissure is the main cause of anal pain and is very common." | 1.31 | Open lateral sphincterotomy is still the best treatment for chronic anal fissure. ( Argov, S; Levandovsky, O, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (39.13) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Brillantino, A | 1 |
| Renzi, A | 1 |
| Talento, P | 1 |
| Iacobellis, F | 1 |
| Brusciano, L | 1 |
| Monaco, L | 1 |
| Izzo, D | 1 |
| Giordano, A | 1 |
| Pinto, M | 1 |
| Fantini, C | 1 |
| Gasparrini, M | 1 |
| Schiano Di Visconte, M | 1 |
| Milazzo, F | 1 |
| Ferreri, G | 1 |
| Braini, A | 1 |
| Cocozza, U | 1 |
| Pezzatini, M | 1 |
| Gianfreda, V | 1 |
| Di Leo, A | 1 |
| Landolfi, V | 1 |
| Favetta, U | 1 |
| Agradi, S | 1 |
| Marino, G | 1 |
| Varriale, M | 1 |
| Mongardini, M | 1 |
| Pagano, CEFA | 1 |
| Contul, RB | 1 |
| Gallese, N | 1 |
| Ucchino, G | 1 |
| D'Ambra, M | 1 |
| Rizzato, R | 1 |
| Sarzo, G | 1 |
| Masci, B | 1 |
| Da Pozzo, F | 1 |
| Ascanelli, S | 1 |
| Foroni, F | 1 |
| Palumbo, A | 1 |
| Liguori, P | 1 |
| Pezzolla, A | 1 |
| Marano, L | 1 |
| Capomagi, A | 1 |
| Cudazzo, E | 1 |
| Babic, F | 1 |
| Geremia, C | 1 |
| Bussotti, A | 1 |
| Cicconi, M | 1 |
| Di Sarno, A | 1 |
| Mongardini, FM | 1 |
| Brescia, A | 1 |
| Lenisa, L | 1 |
| Mistrangelo, M | 1 |
| Sotelo, MLS | 1 |
| Vicenzo, L | 1 |
| Longo, A | 1 |
| Docimo, L | 1 |
| Sarıışık, AM | 1 |
| Karavana, SY | 1 |
| Türkoğlu, GC | 1 |
| Rençber, S | 1 |
| Önder, T | 1 |
| Salem, AE | 1 |
| Mohamed, EA | 1 |
| Elghadban, HM | 1 |
| Abdelghani, GM | 1 |
| Klin, B | 1 |
| Efrati, Y | 1 |
| Berkovitch, M | 1 |
| Abu-Kishk, I | 1 |
| Medhi, B | 1 |
| Rao, RS | 1 |
| Prakash, A | 1 |
| Prakash, O | 1 |
| Kaman, L | 1 |
| Pandhi, P | 1 |
| Karamanlis, E | 1 |
| Michalopoulos, A | 1 |
| Papadopoulos, V | 1 |
| Mekras, A | 1 |
| Panagiotou, D | 1 |
| Ioannidis, A | 1 |
| Basdanis, G | 1 |
| Fahantidis, E | 1 |
| Yiannakopoulou, E | 1 |
| Cevik, M | 1 |
| Boleken, ME | 1 |
| Koruk, I | 1 |
| Ocal, S | 1 |
| Balcioglu, ME | 1 |
| Aydinoglu, A | 1 |
| Karadag, CA | 1 |
| Sönmez, K | 1 |
| Demiroğullari, B | 1 |
| Ekingen, G | 1 |
| Türkyilmaz, Z | 1 |
| Karabulut, R | 1 |
| Başaklar, AC | 1 |
| Kale, N | 1 |
| Perrotti, P | 1 |
| Bove, A | 1 |
| Antropoli, C | 1 |
| Molino, D | 1 |
| Antropoli, M | 1 |
| Balzano, A | 1 |
| De Stefano, G | 1 |
| Attena, F | 1 |
| Merenstein, D | 1 |
| Rosenbaum, D | 1 |
| Ahmad, J | 1 |
| Andrabi, SI | 1 |
| Rathore, MA | 1 |
| McDonald, P | 1 |
| Driscoll, AM | 1 |
| Nicholls, RJ | 1 |
| Gough, MJ | 1 |
| Lewis, A | 1 |
| Bacher, H | 1 |
| Mischinger, HJ | 1 |
| Werkgartner, G | 1 |
| Cerwenka, H | 1 |
| El-Shabrawi, A | 1 |
| Pfeifer, J | 1 |
| Schweiger, W | 1 |
| Argov, S | 1 |
| Levandovsky, O | 1 |
| Götze, KJ | 1 |
| Kratzer, GL | 1 |
| Moore, KT | 1 |
| Jensen, SL | 1 |
| Tagart, RE | 1 |
| DiGiovanni, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Evaluation of MEBO Ointment and Topical Diltiazem Ointment in the Treatment of Acute Anal Fissure: a Randomized Clinical Trial[NCT04153032] | Phase 2 | 183 participants (Anticipated) | Interventional | 2019-12-01 | Recruiting | ||
| Effects of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure[NCT04320498] | Phase 4 | 41 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| Randomized Controlled Trial Comparing the Efficacy of Polyethylene Glycol Alone and Polyethylene Glycol Combined With Topical Diltiazem in Treating Anal fissure in Children[NCT02419534] | Phase 4 | 46 participants (Anticipated) | Interventional | 2014-11-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for lidocaine and Fissure in Ano
| Article | Year |
|---|---|
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Botulinum toxin and anal fissure: efficacy and safety systematic review.
Topics: Botulinum Toxins; Dose-Response Relationship, Drug; Fissure in Ano; Humans; Lidocaine; Nitrates; Pla | 2012 |
Haemorrhoids and palpable ano-rectal lesions.
Topics: Anus Diseases; Betamethasone; Endoscopy; Fissure in Ano; Hemorrhoids; Humans; Hyaluronoglucosaminida | 1974 |
10 trials available for lidocaine and Fissure in Ano
| Article | Year |
|---|---|
Potential combination topical therapy of anal fissure: development, evaluation, and clinical study†.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; B | 2018 |
Prospective clinical trial comparing sphincterotomy, nitroglycerin ointment and xylocaine/lactulose combination for the treatment of anal fissure.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Anal Canal; Combined Modality Therapy; D | 2010 |
A prospective, randomized, double-blind study comparing the efficacy of diltiazem, glyceryl trinitrate, and lidocaine for the treatment of anal fissure in children.
Topics: Anesthetics, Local; Child; Child, Preschool; Diltiazem; Double-Blind Method; Female; Fissure in Ano; | 2012 |
Randomized, placebo-controlled treatment of anal fissure by lidocaine, EMLA, and GTN in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Female; Fissure in | 2002 |
Topical nifedipine with lidocaine ointment vs. active control for treatment of chronic anal fissure: results of a prospective, randomized, double-blind study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Chronic Disease; Double-Blind Method; Drug Combina | 2002 |
Comparison of topical glyceryl trinitrate with lignocaine ointment for treatment of anal fissure: a randomised controlled trial.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Child; Double-Blind Method; Female; | 2007 |
The anal dilator in the conservative management of acute anal fissures.
Topics: Acute Disease; Adolescent; Adult; Aged; Clinical Trials as Topic; Dilatation; Female; Fissure in Ano | 1983 |
The conservative treatment of fissure-in-ano.
Topics: Administration, Topical; Adolescent; Adult; Aged; Clinical Trials as Topic; Dilatation; Female; Fiss | 1983 |
Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy?
Topics: Acute Disease; Administration, Rectal; Administration, Topical; Adult; Anal Canal; Anesthetics, Loca | 1997 |
Treatment of first episodes of acute anal fissure: prospective randomised study of lignocaine ointment versus hydrocortisone ointment or warm sitz baths plus bran.
Topics: Acute Disease; Adult; Baths; Clinical Trials as Topic; Dietary Fiber; Female; Fissure in Ano; Humans | 1986 |
10 other studies available for lidocaine and Fissure in Ano
| Article | Year |
|---|---|
The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure.
Topics: Anal Canal; Chronic Disease; Colon; Colorectal Surgery; Fissure in Ano; Humans; Lidocaine; Treatment | 2023 |
Preparation and characterization of textile-based carrier systems for anal fissure treatment.
Topics: Alginates; Anesthetics, Local; Drug Carriers; Drug Delivery Systems; Drug Liberation; Fissure in Ano | 2017 |
Anal fissure in children: a 10-year clinical experience with nifedipine gel with lidocaine.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Drug Combinations; | 2016 |
Is topical nifedipine effective for chronic anal fissures?
Topics: Administration, Topical; Anesthetics, Local; Chronic Disease; Double-Blind Method; Evidence-Based Me | 2003 |
Treating fissure in ano in outpatients: what dose of local anesthetic?
Topics: Ambulatory Surgical Procedures; Anesthesia, Rectal; Fissure in Ano; Humans; Lidocaine | 1984 |
Open lateral sphincterotomy is still the best treatment for chronic anal fissure.
Topics: Ambulatory Surgical Procedures; Anal Canal; Anesthetics, Local; Bupivacaine; Chronic Disease; Fissur | 2000 |
[Sphincter surgery. Etiology and therapy of the anal fissure (author's transl)].
Topics: Adolescent; Adult; Anal Canal; Constipation; Female; Fissure in Ano; Humans; Lidocaine; Male; Middle | 1976 |
Outpatient anorectal surgery.
Topics: Abscess; Ambulatory Care; Anal Canal; Anesthesia, Local; Anus Diseases; Bandages; Cathartics; Coloni | 1975 |
The outpatient treatment of fissure-in-ano.
Topics: Ambulatory Care; Anesthesia, Local; Fissure in Ano; Humans; Lidocaine; Suppositories | 1975 |
Inadvertent intraosseous injection--a hazard of caudal anesthesia.
Topics: Anesthesia, Spinal; Bone Marrow; Fissure in Ano; Humans; Lidocaine; Lumbosacral Region; Male; Middle | 1971 |