Page last updated: 2024-10-28

lidocaine and Fibromyalgia

lidocaine has been researched along with Fibromyalgia in 32 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
"The combination of 240 mg of intravenous lidocaine (once a week for 4 weeks) with 25 mg of amitriptyline for 8 weeks had no meaningful impact in fibromyalgia patients."9.22Effect of intravenous lidocaine combined with amitriptyline on pain intensity, clinical manifestations and the concentrations of IL-1, IL-6 and IL-8 in patients with fibromyalgia: A randomized double-blind study. ( Albertoni Giraldes, AL; Brunialti, MK; Leal, PD; Sakata, RK; Salomão, R, 2016)
"Combined administration of 240 mg intravenous lidocaine (once a week) and 25 mg amitriptyline for 4 weeks did not modify pain intensity or plasma serotonin, norepinephrine, or dopamine concentrations in fibromyalgia patients."9.15Effect of intravenous lidocaine associated with amitriptyline on pain relief and plasma serotonin, norepinephrine, and dopamine concentrations in fibromyalgia. ( Issy, AM; Sakata, RK; Vlainich, R, 2011)
"To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes."9.08The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995)
"Pain intensity, muscle strength, static muscle endurance, pressure pain threshold, and pain tolerance at tender points and control points were assessed in 31 patients with fibromyalgia (FM), before and after intravenous administration of morphine (9 patients), lidocaine (11 patients), and ketamine (11 patients)."9.08Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine. ( Bäckman, E; Bengtsson, A; Bengtsson, M; Henriksson, KG; Sörensen, J, 1995)
"To determine the effect of escalating doses of lidocaine infusion with or without added magnesium on pain levels and the duration of pain relief in patients with fibromyalgia (FM)."7.96Repeated Intravenous Lidocaine Infusions for Patients with Fibromyalgia: Higher Doses of Lidocaine Have a Stronger and Longer-Lasting Effect on Pain Reduction. ( Perelman, VS; Pugacheva, O; Voznyak, Y; Wansbrough, MCT; Wilderman, I; Zolnierczyk, L, 2020)
"Primary mechanical hyperalgesia at the shoulders and buttocks decreased significantly more after lidocaine than saline injections (p = 0."6.79Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome. ( Bartley, E; Price, DD; Robinson, ME; Staud, R; Weyl, EE, 2014)
"Fibromyalgia Impact Questionnaire (FIQ), Health Assessment Questionnaire, and a visual analog scale (VAS) for pain were applied before the first lidocaine infusion, immediately after the fifth infusion and 30 days after the fifth infusion."6.74Intravenous lidocaine for fibromyalgia syndrome: an open trial. ( Harth, F; Kaiber, F; Machado, F; Malucelli, T; Schafranski, MD; Schmidt, C; Takeshi, H, 2009)
"To compare the analgesic effect of anesthetic infiltration of lidocaine 2% and low-level laser therapy (LLLT) by GaAlAs into tender points of patients with orofacial pain and fibromyalgia (FM)."5.27Low-level laser therapy and anesthetic infiltration for orofacial pain in patients with fibromyalgia: a randomized clinical trial. ( de Oliveira E Silva, EM; de Sousa, ET; de Souza, RC; Gomes, AC; Limeira-Junior, FA; Meira, UM; Scudine, KG, 2018)
"The combination of 240 mg of intravenous lidocaine (once a week for 4 weeks) with 25 mg of amitriptyline for 8 weeks had no meaningful impact in fibromyalgia patients."5.22Effect of intravenous lidocaine combined with amitriptyline on pain intensity, clinical manifestations and the concentrations of IL-1, IL-6 and IL-8 in patients with fibromyalgia: A randomized double-blind study. ( Albertoni Giraldes, AL; Brunialti, MK; Leal, PD; Sakata, RK; Salomão, R, 2016)
"Combined administration of 240 mg intravenous lidocaine (once a week) and 25 mg amitriptyline for 4 weeks did not modify pain intensity or plasma serotonin, norepinephrine, or dopamine concentrations in fibromyalgia patients."5.15Effect of intravenous lidocaine associated with amitriptyline on pain relief and plasma serotonin, norepinephrine, and dopamine concentrations in fibromyalgia. ( Issy, AM; Sakata, RK; Vlainich, R, 2011)
"Lidocaine injections increased local pain thresholds and decreased remote secondary heat hyperalgesia in FM patients, emphasizing the important role of peripheral impulse input in maintaining central sensitization in this chronic pain syndrome; similar to other persistent pain conditions such as irritable bowel syndrome and complex regional pain syndrome."5.14Enhanced central pain processing of fibromyalgia patients is maintained by muscle afferent input: a randomized, double-blind, placebo-controlled study. ( Nagel, S; Price, DD; Robinson, ME; Staud, R, 2009)
"To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes."5.08The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995)
"Pain intensity, muscle strength, static muscle endurance, pressure pain threshold, and pain tolerance at tender points and control points were assessed in 31 patients with fibromyalgia (FM), before and after intravenous administration of morphine (9 patients), lidocaine (11 patients), and ketamine (11 patients)."5.08Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine. ( Bäckman, E; Bengtsson, A; Bengtsson, M; Henriksson, KG; Sörensen, J, 1995)
"To determine the effect of escalating doses of lidocaine infusion with or without added magnesium on pain levels and the duration of pain relief in patients with fibromyalgia (FM)."3.96Repeated Intravenous Lidocaine Infusions for Patients with Fibromyalgia: Higher Doses of Lidocaine Have a Stronger and Longer-Lasting Effect on Pain Reduction. ( Perelman, VS; Pugacheva, O; Voznyak, Y; Wansbrough, MCT; Wilderman, I; Zolnierczyk, L, 2020)
"Primary mechanical hyperalgesia at the shoulders and buttocks decreased significantly more after lidocaine than saline injections (p = 0."2.79Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome. ( Bartley, E; Price, DD; Robinson, ME; Staud, R; Weyl, EE, 2014)
"Fibromyalgia Impact Questionnaire (FIQ), Health Assessment Questionnaire, and a visual analog scale (VAS) for pain were applied before the first lidocaine infusion, immediately after the fifth infusion and 30 days after the fifth infusion."2.74Intravenous lidocaine for fibromyalgia syndrome: an open trial. ( Harth, F; Kaiber, F; Machado, F; Malucelli, T; Schafranski, MD; Schmidt, C; Takeshi, H, 2009)
"Ten patients with primary fibromyalgia syndrome were treated with intravenous infusions of lignocaine on a daily basis for six days."2.68Intravenous lignocaine in the management of primary fibromyalgia syndrome. ( Bennett, MI; Tai, YM, 1995)
"Pain was analyzed in patients with fibromyalgia (FM) in a randomized, double blind, crossover study using intravenous (i."2.68Fibromyalgia--are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs. ( Ahlner, J; Bengtsson, A; Bengtsson, M; Ekselius, L; Henriksson, KG; Sörensen, J, 1997)
"Enhanced somatic pains are accompanied by mechanical hyperalgesia and allodynia in FM patients as compared with healthy controls."2.46Is it all central sensitization? Role of peripheral tissue nociception in chronic musculoskeletal pain. ( Staud, R, 2010)
"Primary fibromyalgia is a common but often unrecognized rheumatic condition."1.26Primary fibromyalgia. ( Calabro, JJ; Masi, AT; Shah, IK; Yunus, M, 1982)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.88)18.7374
1990's10 (31.25)18.2507
2000's4 (12.50)29.6817
2010's9 (28.13)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Wilderman, I1
Pugacheva, O1
Perelman, VS1
Wansbrough, MCT1
Voznyak, Y1
Zolnierczyk, L1
Rezasoltani, Z1
Ehyaie, H1
Mofrad, RK1
Vashaei, F1
Mohtasham, R1
Najafi, S1
de Souza, RC1
de Sousa, ET1
Scudine, KG1
Meira, UM1
de Oliveira E Silva, EM1
Gomes, AC1
Limeira-Junior, FA1
Niraj, G1
Staud, R3
Weyl, EE1
Bartley, E1
Price, DD2
Robinson, ME2
Albertoni Giraldes, AL1
Salomão, R1
Leal, PD1
Brunialti, MK1
Sakata, RK2
Moon, JJ1
Ahn, MW1
Ahn, HS1
Lee, SJ1
Lee, DY1
Schafranski, MD1
Malucelli, T1
Machado, F1
Takeshi, H1
Kaiber, F1
Schmidt, C1
Harth, F1
Nagel, S1
Geber, C1
Vlainich, R1
Issy, AM1
Furuta, A1
Suzuki, Y1
Honda, M1
Koike, Y1
Naruoka, T1
Asano, K1
Chancellor, M1
Egawa, S1
Yoshimura, N1
Raphael, JH1
Southall, JL1
Kitas, GD1
GALLETTI, R1
PROCACCI, P1
MARCHETTI, PG1
ROCCHI, P1
BUZZELLI, G1
Ga, H1
Koh, HJ1
Choi, JH1
Kim, CH1
Yunus, M1
Masi, AT1
Calabro, JJ1
Shah, IK1
Scudds, RA1
Janzen, V1
Delaney, G1
Heck, C1
McCain, GA1
Russell, AL1
Teasell, RW1
Varkey, G1
Woodbury, GM1
Bassan, H1
Niv, D1
Jourgenson, U1
Wientroub, S1
Spirer, Z1
Sörensen, J3
Bengtsson, A2
Bäckman, E1
Henriksson, KG2
Bengtsson, M2
Kosek, E1
Ekholm, J1
Hansson, P2
Paulson, GW1
Gill, W1
Bennett, MI1
Tai, YM1
Hong, CZ1
Hsueh, TC1
Ahlner, J1
Ekselius, L1
Janzen, VD1
Scudds, R1
Arnér, S1
Gustafsson, L1
Kinnman, E1
Sollevi, A1
Crile, G1
Annexton, M1
Coulehan, JL1
Kraus, H1
Trojaborg, W1
Rowland, LP1
Katz, RI1
Wheaton, EA1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624]Phase 480 participants (Anticipated)Interventional2019-08-01Recruiting
What Determines a Positive Outcome of Spinal Manipulation for Persistent Low Back Pain: Stiffness or Pain Sensitivity? A Randomized Trial[NCT04086667]132 participants (Actual)Interventional2017-11-01Completed
Dry Needling in Patients With Fibromyalgia: Analysis of Its Therapeutic Effectiveness[NCT04942444]120 participants (Anticipated)Interventional2011-01-10Recruiting
Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012]Phase 410 participants (Actual)Interventional2017-05-02Terminated (stopped due to Poor enrollment.)
Nitrous Oxide as Treatment for Fibromyalgia[NCT05357066]Phase 250 participants (Anticipated)Interventional2021-11-12Recruiting
Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313]152 participants (Actual)Interventional2015-03-31Active, not recruiting
Treating Trigger Points: Comparing Muscle Energy Technique vs. Lidocaine Needling Technique for Pain Control and Quality of Life Measurements[NCT05009264]32 participants (Actual)Observational2022-01-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With a Responder Rate Greater Than 50% on the Numeric Rating Pain Scale (NRS) Improvement

Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months

InterventionParticipants (Count of Participants)
Ketorolac1
Lidocaine0
Dexamethasone0

Brief Pain Inventory (BPI) - Modified

The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months

Interventionscore on a scale (Number)
Participant Number #3 at BaselineParticipant Number #3 at 3 MonthsParticipant Number #8 at BaselineParticipant #8 at 3 Months
Ketorolac8353

Numeric Rating Pain Scale (NRS) at Baseline and Three Months.

TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)

Interventionscore on a scale (Number)
Participant Number 3 at BaselineParticipant Number 3 at 3 MonthsParticipant Number 8 at BaselineParticipant Number 8 at 3 Months
Ketorolac8353

Reviews

2 reviews available for lidocaine and Fibromyalgia

ArticleYear
Is it all central sensitization? Role of peripheral tissue nociception in chronic musculoskeletal pain.
    Current rheumatology reports, 2010, Volume: 12, Issue:6

    Topics: Anesthetics, Local; Exercise Therapy; Fibromyalgia; Humans; Hyperalgesia; Lidocaine; Muscle, Skeleta

2010
[Pharmacological pain analysis as diagnostic and therapeutic help].
    Lakartidningen, 1998, Jun-10, Volume: 95, Issue:24

    Topics: Adenosine; Analgesics, Opioid; Anesthetics, Local; Animals; Fibromyalgia; Humans; Ketamine; Lidocain

1998

Trials

15 trials available for lidocaine and Fibromyalgia

ArticleYear
Granisetron vs. lidocaine injection to trigger points in the management of myofascial pain syndrome: a double-blind randomized clinical trial.
    Scandinavian journal of pain, 2021, 10-26, Volume: 21, Issue:4

    Topics: Fibromyalgia; Granisetron; Humans; Lidocaine; Myofascial Pain Syndromes; Trigger Points

2021
Low-level laser therapy and anesthetic infiltration for orofacial pain in patients with fibromyalgia: a randomized clinical trial.
    Medicina oral, patologia oral y cirugia bucal, 2018, Jan-01, Volume: 23, Issue:1

    Topics: Anesthesia, Local; Anesthetics, Local; Facial Pain; Female; Fibromyalgia; Humans; Lasers, Semiconduc

2018
Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome.
    European journal of pain (London, England), 2014, Volume: 18, Issue:6

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Fibromyalgia; Humans; Hyperalgesia; Injectio

2014
Effect of intravenous lidocaine combined with amitriptyline on pain intensity, clinical manifestations and the concentrations of IL-1, IL-6 and IL-8 in patients with fibromyalgia: A randomized double-blind study.
    International journal of rheumatic diseases, 2016, Volume: 19, Issue:10

    Topics: Administration, Intravenous; Adult; Amitriptyline; Anesthetics, Local; Biomarkers; Brazil; Double-Bl

2016
Intravenous lidocaine for fibromyalgia syndrome: an open trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:7

    Topics: Adult; Anesthetics, Local; Female; Fibromyalgia; Health Status; Humans; Infusions, Intravenous; Lido

2009
Enhanced central pain processing of fibromyalgia patients is maintained by muscle afferent input: a randomized, double-blind, placebo-controlled study.
    Pain, 2009, Volume: 145, Issue:1-2

    Topics: Adult; Afferent Pathways; Analysis of Variance; Anesthetics, Local; Arm; Double-Blind Method; Female

2009
Effect of intravenous lidocaine associated with amitriptyline on pain relief and plasma serotonin, norepinephrine, and dopamine concentrations in fibromyalgia.
    The Clinical journal of pain, 2011, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Amitriptyline; Analgesics; Catecholamines; Dopamine; Double-Blind Method; Drug Th

2011
Intramuscular and nerve root stimulation vs lidocaine injection to trigger points in myofascial pain syndrome.
    Journal of rehabilitation medicine, 2007, Volume: 39, Issue:5

    Topics: Aged; Anesthetics, Local; Electric Stimulation Therapy; Female; Fibromyalgia; Humans; Injections, In

2007
The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial.
    Pain, 1995, Volume: 62, Issue:1

    Topics: Administration, Topical; Adult; Anxiety; Autonomic Nerve Block; Chronic Disease; Depression; Double-

1995
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
    Scandinavian journal of rheumatology, 1995, Volume: 24, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal

1995
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
    Scandinavian journal of rheumatology, 1995, Volume: 24, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal

1995
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
    Scandinavian journal of rheumatology, 1995, Volume: 24, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal

1995
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
    Scandinavian journal of rheumatology, 1995, Volume: 24, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal

1995
Increased pressure pain sensibility in fibromyalgia patients is located deep to the skin but not restricted to muscle tissue.
    Pain, 1995, Volume: 63, Issue:3

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; Fibromyalgia; Humans; Lid

1995
Botulinum toxin is unsatisfactory therapy for fibromyalgia.
    Movement disorders : official journal of the Movement Disorder Society, 1996, Volume: 11, Issue:4

    Topics: Botulinum Toxins; Double-Blind Method; Female; Fibromyalgia; Humans; Injections, Intramuscular; Lido

1996
Intravenous lignocaine in the management of primary fibromyalgia syndrome.
    International journal of clinical pharmacology research, 1995, Volume: 15, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Female; Fibromyalgia; Humans; Infusions, Intravenous; Lidocaine; Mi

1995
Fibromyalgia--are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs.
    The Journal of rheumatology, 1997, Volume: 24, Issue:8

    Topics: Adult; Anesthetics, Dissociative; Area Under Curve; Cross-Over Studies; Double-Blind Method; Drug Th

1997
Sphenopalatine blocks in the treatment of pain in fibromyalgia and myofascial pain syndrome.
    The Laryngoscope, 1997, Volume: 107, Issue:10

    Topics: Anesthetics, Local; Autonomic Nerve Block; Double-Blind Method; Female; Fibromyalgia; Follow-Up Stud

1997

Other Studies

15 other studies available for lidocaine and Fibromyalgia

ArticleYear
Repeated Intravenous Lidocaine Infusions for Patients with Fibromyalgia: Higher Doses of Lidocaine Have a Stronger and Longer-Lasting Effect on Pain Reduction.
    Pain medicine (Malden, Mass.), 2020, 06-01, Volume: 21, Issue:6

    Topics: Anesthetics, Local; Fibromyalgia; Humans; Infusions, Intravenous; Lidocaine; Pain; Pain Measurement;

2020
Pathophysiology and Management of Abdominal Myofascial Pain Syndrome (AMPS): A Three-Year Prospective Audit of a Management Pathway in 120 Patients.
    Pain medicine (Malden, Mass.), 2018, 11-01, Volume: 19, Issue:11

    Topics: Abdominal Pain; Adult; Aged; Anesthetics, Local; Female; Fibromyalgia; Humans; Lidocaine; Male; Midd

2018
Usefulness of K-Point Injection for the Nonspecific Neck Pain in So-Called K-Point Syndrome.
    Clinics in orthopedic surgery, 2016, Volume: 8, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dexamethasone; Female; Fibromyalgia; Humans; Inj

2016
Spotting the pain in fibromyalgia syndrome--widespread effects of local pain therapy.
    European journal of pain (London, England), 2011, Volume: 15, Issue:1

    Topics: Anesthetics, Local; Arthralgia; Facial Pain; Fibromyalgia; Humans; Lidocaine; Pain; Syndrome; Treatm

2011
Time-dependent changes in bladder function and plantar sensitivity in a rat model of fibromyalgia syndrome induced by hydrochloric acid injection into the gluteus.
    BJU international, 2012, Volume: 109, Issue:2

    Topics: Anesthetics, Local; Animals; Case-Control Studies; Chronic Pain; Disease Models, Animal; Female; Fib

2012
Adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome.
    Rheumatology (Oxford, England), 2003, Volume: 42, Issue:1

    Topics: Adult; Aged; Female; Fibromyalgia; Humans; Hypertension, Pulmonary; Hypotension; Infusions, Intraven

2003
[EXPLORATION OF THE SENSORY FUNCTION OF THE UPPER LIMB AND OF THE CORRELATED CUTANEOUS PHENOMENA IN FIBROMYALGIAS. EFFECTS OF BLOCKING OF THE SENSORY PATHWAYS AND STELLATE GANGLION].
    Archivio di fisiologia, 1963, Dec-30, Volume: 62

    Topics: Arm; Autonomic Nerve Block; Electrophysiology; Fibromyalgia; Humans; Lidocaine; Muscular Diseases; P

1963
Primary fibromyalgia.
    American family physician, 1982, Volume: 25, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Diagnosis, Differential; Female; Fibromyalgia; Humans; Lidocaine; M

1982
Localized fibromyalgia in a child.
    Paediatric anaesthesia, 1995, Volume: 5, Issue:4

    Topics: Adolescent; Anesthetics, Local; Anti-Inflammatory Agents; Fibromyalgia; Humans; Lidocaine; Male; Met

1995
Difference in pain relief after trigger point injections in myofascial pain patients with and without fibromyalgia.
    Archives of physical medicine and rehabilitation, 1996, Volume: 77, Issue:11

    Topics: Adult; Anesthetics, Local; Female; Fibromyalgia; Humans; Injections, Intramuscular; Lidocaine; Middl

1996
Difference in pain relief after trigger point injections in myofascial pain patients with and without fibromyalgia.
    Archives of physical medicine and rehabilitation, 1996, Volume: 77, Issue:11

    Topics: Adult; Anesthetics, Local; Female; Fibromyalgia; Humans; Injections, Intramuscular; Lidocaine; Middl

1996
Difference in pain relief after trigger point injections in myofascial pain patients with and without fibromyalgia.
    Archives of physical medicine and rehabilitation, 1996, Volume: 77, Issue:11

    Topics: Adult; Anesthetics, Local; Female; Fibromyalgia; Humans; Injections, Intramuscular; Lidocaine; Middl

1996
Difference in pain relief after trigger point injections in myofascial pain patients with and without fibromyalgia.
    Archives of physical medicine and rehabilitation, 1996, Volume: 77, Issue:11

    Topics: Adult; Anesthetics, Local; Female; Fibromyalgia; Humans; Injections, Intramuscular; Lidocaine; Middl

1996
Injection of steroids in painful breasts.
    American journal of surgery, 1977, Volume: 133, Issue:6

    Topics: Adult; Drug Combinations; Female; Fibromyalgia; Humans; Injections; Lidocaine; Mastitis; Middle Aged

1977
Arthrography can help free 'frozen shoulder'.
    JAMA, 1979, Mar-02, Volume: 241, Issue:9

    Topics: Fibromyalgia; Humans; Injections, Intra-Articular; Iothalamate Meglumine; Lidocaine; Radiography; Sh

1979
Primary fibromyalgia.
    American family physician, 1985, Volume: 32, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents; Arthritis; Chlorofluorocarbons, Methane; Diagnosi

1985
Triggerpoints.
    New York state journal of medicine, 1973, Jun-01, Volume: 73, Issue:11

    Topics: Fibromyalgia; Humans; Injections, Intramuscular; Lidocaine; Muscle Cramp; Muscle Rigidity; Muscles

1973
Stiff muscles and bony tendons.
    Transactions of the American Neurological Association, 1970, Volume: 95

    Topics: Adult; Affective Symptoms; Amobarbital; Diazepam; Dihydroxyphenylalanine; Electromyography; Female;

1970