lidocaine has been researched along with Fasciculation in 6 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Fasciculation: Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Succinylcholine is used during induction of anesthesia, and it may induce fasciculations." | 9.12 | Lidocaine or diazepam can decrease fasciculation induced by succinylcholine during induction of anesthesia. ( Hassani, M; Sahraian, MA, 2006) |
| "To determine the attenuation in the incidence of myalgia, fasciculations and changes in serum potassium and creatinine kinase concentrations when atracurium and lidocaine were used in combination and separately as pretreatment before succinylcholine." | 9.08 | Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment. ( Raman, SK; San, WM, 1997) |
| "In controls, the incidence of fasciculation was 95%, and the incidence of myalgia at 24 h was 50%." | 6.43 | Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. ( Fuchs-Buder, T; Lysakowski, C; Schreiber, JU; Tramèr, MR, 2005) |
| "To determine the attenuation in the incidence of myalgia, fasciculations and changes in serum potassium and creatinine kinase concentrations when atracurium and lidocaine were used in combination and separately as pretreatment before succinylcholine." | 5.08 | Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment. ( Raman, SK; San, WM, 1997) |
| "The results indicate that muscle fasciculation was not found in Group PR while the patients in Group LS had a lower incidence of muscle fasciculation than those in Group PS (p < 0." | 2.70 | Can lidocaine reduce succinylcholine induced postoperative myalgia? ( Amornyotin, S; Nilsuwankosit, P; Pipatnaraphong, H; Rachatamukayanant, P; Santawat, U, 2002) |
| "In controls, the incidence of fasciculation was 95%, and the incidence of myalgia at 24 h was 50%." | 2.43 | Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. ( Fuchs-Buder, T; Lysakowski, C; Schreiber, JU; Tramèr, MR, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taha, SK | 1 |
| El-Khatib, MF | 1 |
| Baraka, AS | 1 |
| Haidar, YA | 1 |
| Abdallah, FW | 1 |
| Zbeidy, RA | 1 |
| Siddik-Sayyid, SM | 1 |
| Amornyotin, S | 1 |
| Santawat, U | 1 |
| Rachatamukayanant, P | 1 |
| Nilsuwankosit, P | 1 |
| Pipatnaraphong, H | 1 |
| Schreiber, JU | 1 |
| Lysakowski, C | 1 |
| Fuchs-Buder, T | 1 |
| Tramèr, MR | 1 |
| Hassani, M | 1 |
| Sahraian, MA | 1 |
| Raman, SK | 1 |
| San, WM | 1 |
| Naguib, M | 1 |
| Farag, H | 1 |
| Magbagbeola, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "A Less-rapid Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the Duration of Apnea Without Desaturation in Paralyzed Non-obese and Morbidly Obese Patients?"[NCT02943629] | 0 participants (Actual) | Interventional | 2016-11-30 | Withdrawn (stopped due to Lack of feasibility) | |||
| The Effect of Precurarization With Rocuronium on the Incidence and Severity of Succinylcholine-Induced Fasciculations and Myalgias in a High Volume ERCP Center[NCT04581395] | Phase 3 | 300 participants (Actual) | Interventional | 2020-10-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lidocaine and Fasciculation
| Article | Year |
|---|---|
Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fasciculation; Humans; Li | 2005 |
5 trials available for lidocaine and Fasciculation
| Article | Year |
|---|---|
Effect of suxamethonium vs rocuronium on onset of oxygen desaturation during apnoea following rapid sequence induction.
Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Fasci | 2010 |
Can lidocaine reduce succinylcholine induced postoperative myalgia?
Topics: Adolescent; Adult; Aged; Analysis of Variance; Androstanols; Anesthetics, Local; Chi-Square Distribu | 2002 |
Lidocaine or diazepam can decrease fasciculation induced by succinylcholine during induction of anesthesia.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Blood Pressure; Diazepam; Elective | 2006 |
Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment.
Topics: Adult; Atracurium; Creatine Kinase; Double-Blind Method; Fasciculation; Female; Humans; Lidocaine; M | 1997 |
Failure of lidocaine to modify suxamethonium induced biochemical changes.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Fasciculation; Female; Humans; Lidocaine; Pros | 1988 |