Page last updated: 2024-10-28

lidocaine and Eye Pain

lidocaine has been researched along with Eye Pain in 23 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Eye Pain: A dull or sharp painful sensation associated with the outer or inner structures of the eyeball, having different causes.

Research Excerpts

ExcerptRelevanceReference
"This study aims to evaluate postoperative pain management using topical lidocaine gel after DMEK with iatrogenic corneal abrasion."5.91Immediate postoperative topical lidocaine gel for the treatment of eye pain following corneal abrasion in descemet membrane endothelial keratoplasty (DMEK) under general anaesthesia: a pilot retrospective analysis. ( Bachmann, B; Böttiger, BW; Cursiefen, C; Heindl, LM; Leister, N; Löw, V; Matthaei, M; Schrittenlocher, S; Schumacher, C; Trieschmann, U, 2023)
"This study aims to evaluate postoperative pain management using topical lidocaine gel after DMEK with iatrogenic corneal abrasion."1.91Immediate postoperative topical lidocaine gel for the treatment of eye pain following corneal abrasion in descemet membrane endothelial keratoplasty (DMEK) under general anaesthesia: a pilot retrospective analysis. ( Bachmann, B; Böttiger, BW; Cursiefen, C; Heindl, LM; Leister, N; Löw, V; Matthaei, M; Schrittenlocher, S; Schumacher, C; Trieschmann, U, 2023)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's22 (95.65)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Leister, N1
Bachmann, B1
Matthaei, M1
Trieschmann, U1
Schumacher, C1
Löw, V1
Böttiger, BW1
Schrittenlocher, S1
Heindl, LM1
Cursiefen, C1
Mak, MYK1
Yan, P1
Park, J1
Joshi, L1
Warder, D1
Lee, C1
Gulamhusein, H1
Devenyi, RG1
Lam, WC1
Theventhiran, A1
Shabsigh, M1
De Moraes, CG1
Cioffi, GA1
Kamel, M1
Blumberg, D1
Al-Aswad, LA1
Tasman, AJ1
Sasajima, H1
Tsuboi, K1
Ono, H1
Murotani, K1
Kamei, M1
Scuderi, G1
Scuderi, L1
Calafiore, S1
Fenicia, V1
Abdolrahimzadeh, S1
Crabb, MG1
Liu, E1
Freeman, A1
Hsu, T1
Supramaniam, D1
Kaidonis, G1
Glading, J1
Keane, MC1
Cugati, S1
Lake, SR1
Saha, N1
Landers, J1
Craig, JE1
Lundqvist, O1
Koskela, T1
Behndig, A1
Moisseiev, E1
Regenbogen, M1
Rabinovitch, T1
Barak, A1
Loewenstein, A1
Goldstein, M1
Jaichandran, VV1
Raman, R1
Gella, L1
Sharma, T1
Akhtar, N1
Tayyab, A1
Kausar, A1
Jaffar, S1
Matharu, KS1
Smith, SV1
Lee, AG1
LaHood, BR1
Sherwood, D1
Suter, A1
Blaha, GR1
Tilton, EP1
Barouch, FC1
Marx, JL1
Tsatsos, M1
Burnett, CA1
Broadway, DC1
Eke, T1
Çok, OY1
Eker, HE1
Cantürk, S1
Yaycioğlu, R1
Ariboğan, A1
Arslan, G1
Lam, DS1
Law, RW1
Ng, AS1
Lam, PT1
Jhanji, V1
Lee, VY1
Fan, AH1
Rao, SK1
Hou, CH1
Lee, JS1
Chen, KJ1
Lin, KK1
Welch, MN1
Czyz, CN1
Kalwerisky, K1
Holck, DE1
Mihora, LD1
Shinder, R1
Riad, W1
Ahmad, N1
Kumar, CM1
Shah, NV1
Vaddavalli, PK1
Chow, JH1
Roman, JS1
Shi, W1
Yoo, SH1
Sanabria, MR1
Montero, JA1
Losada, MV1
Fernández-Muñoz, M1
Galindo, A1
Fernández, I1
Coco, RM1
Sampedro, A1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of SPI-guided Analgesia With Preventive Different Peribulbar Blocks (PBB) on the Presence of OCR, Postoperative Pain, PONV in Patients Undergoing VRS Under General Anaesthesia: a Randomised, Controlled Trial[NCT03413371]175 participants (Anticipated)Interventional2018-04-26Recruiting
Influence of Surgical Pleth Index-guided Analgesia Using Different Techniques on the Perioperative Outcomes in Patients Undergoing Vitreoretinal Surgery Under General Anaesthesia: Randomised, Controlled Trial[NCT02973581]176 participants (Actual)Interventional2016-02-29Completed
A Prospective, Randomised, Single-masked Comparison of Topical Anesthesia and Topical Combined Subconjunctival (Two-step) Anesthesia in Intravitreal Injection[NCT03871062]60 participants (Anticipated)Interventional2019-03-08Recruiting
Comparison of Three Different Anesthetic Approaches for Intravitreal Injections: A Prospective Randomized Trial[NCT02263690]Phase 492 participants (Actual)Interventional2014-06-30Completed
Effect of Buffered Lidocaine With Epinephrine in Local Anesthesia During Subcutaneous Implantable Venous Access Devices Insertion: Double Blind Randomized Study.[NCT03628430]120 participants (Actual)Interventional2017-01-01Completed
Buffered Lidocaine for Paracervical Block to Decrease Injection Pain During First Trimester Uterine Aspirations[NCT03107754]Phase 498 participants (Actual)Interventional2017-05-15Completed
Comparison of 0.5% Tetracaine Drops Versus 2% Lidocaine Gel for Anesthetic Efficacy and Comfort in Patients Undergoing LASIK[NCT01383200]Phase 411 participants (Actual)Interventional2011-06-30Terminated (stopped due to eyes that received gel had slightly thinner than intended flaps)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Injection Pain

For the primary outcome, pain immediately after paracervical block injection was measured by a scale. The scale used was the 100-mm visual analog scale. The minimum score was 0 and the maximum score was 100. Higher numbers indicate worse pain. (NCT03107754)
Timeframe: Immediately after injection of the paracervical block

Interventionunits on a scale (Median)
Standard Paracervical Block44.5
Buffered Lidocaine Paracervical Block30

Pain After Speculum Placement, Cervical Dilation, and Aspiration

Pain scores were measured at multiple points throughout the procedure. Pain scores were measured using a 100 mm visual analog scale with 0 being no pain and 100 being the worst pain ever. (NCT03107754)
Timeframe: Immediately after speculum placement, cervical dilation, uterine aspiration

,
Interventionunits on a scale (Median)
After insertion of speculumAfter cervical dilationAfter uterine aspiration
Buffered Lidocaine Paracervical Block175569
Standard Paracervical Block1360.0667.5

Participants Score on Pain Scale

Do you have sharp pain in your eye? Pain will be assessed by units on a scale of 1-5: 1 means no symptoms, 2 means slight discomfort, 3 means mild discomfort, 4 means moderate discomfort, and 5 means severe discomfort (NCT01383200)
Timeframe: 1 hour (60minutes) post LASIK operation

InterventionScore on scale (Mean)
Tetracaine1.95
Lidocaine2.01

Reviews

1 review available for lidocaine and Eye Pain

ArticleYear
Reducing Periorbital Edema and Ecchymosis after Rhinoplasty: Literature Review and Personal Approach.
    Facial plastic surgery : FPS, 2018, Volume: 34, Issue:1

    Topics: Adrenal Cortex Hormones; Anticoagulants; Ecchymosis; Edema; Eye Pain; Female; Humans; Hypothermia, I

2018

Trials

11 trials available for lidocaine and Eye Pain

ArticleYear
Pain Associated With a Subconjunctival Cefazolin-Lidocaine Mixture in Retinal Surgery:A Randomized Control Trial.
    Ophthalmic surgery, lasers & imaging retina, 2017, 11-01, Volume: 48, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Bacterial Agents; Cefazolin; Conjunctiva; D

2017
A Randomized Trial of a Short 34-Gauge Needle for Intravitreal Injections.
    Ophthalmology, 2018, Volume: 125, Issue:6

    Topics: Aged; Anesthetics, Local; Angiogenesis Inhibitors; Equipment Design; Eye Movements; Eye Pain; Female

2018
The intravitreal injection pain study: a randomized control study comparing subjective pain with injection technique.
    Acta ophthalmologica, 2019, Volume: 97, Issue:8

    Topics: Administration, Ophthalmic; Adult; Anesthetics, Local; Angiogenesis Inhibitors; Eye Pain; Humans; In

2019
A paired comparison of intracameral mydriatics in refractive lens exchange surgery.
    Acta ophthalmologica, 2014, Volume: 92, Issue:5

    Topics: Administration, Topical; Anterior Chamber; Cyclopentolate; Drug Combinations; Eye Pain; Female; Glar

2014
Local anesthetic agents for vitreoretinal surgery: no advantage to mixing solutions.
    Ophthalmology, 2015, Volume: 122, Issue:5

    Topics: Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cross-Sectiona

2015
Local anesthetic agents for vitreoretinal surgery: no advantage to mixing solutions.
    Ophthalmology, 2015, Volume: 122, Issue:5

    Topics: Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cross-Sectiona

2015
Local anesthetic agents for vitreoretinal surgery: no advantage to mixing solutions.
    Ophthalmology, 2015, Volume: 122, Issue:5

    Topics: Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cross-Sectiona

2015
Local anesthetic agents for vitreoretinal surgery: no advantage to mixing solutions.
    Ophthalmology, 2015, Volume: 122, Issue:5

    Topics: Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cross-Sectiona

2015
Randomized trial of anesthetic methods for intravitreal injections.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies,

2011
Randomized trial of anesthetic methods for intravitreal injections.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies,

2011
Randomized trial of anesthetic methods for intravitreal injections.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies,

2011
Randomized trial of anesthetic methods for intravitreal injections.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies,

2011
Randomized double-masked controlled trial comparing pain scores with and without the use of supplementary 2% lidocaine gel in LASIK.
    American journal of ophthalmology, 2012, Volume: 153, Issue:4

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Eye Pain; Female; Gels; Humans; K

2012
Double-blind, bilateral pain comparison with simultaneous injection of 2% lidocaine versus buffered 2% lidocaine for periocular anesthesia.
    Ophthalmology, 2012, Volume: 119, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Blepharoplasty; Buffers; Doub

2012
Double-blind, bilateral pain comparison with simultaneous injection of 2% lidocaine versus buffered 2% lidocaine for periocular anesthesia.
    Ophthalmology, 2012, Volume: 119, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Blepharoplasty; Buffers; Doub

2012
Double-blind, bilateral pain comparison with simultaneous injection of 2% lidocaine versus buffered 2% lidocaine for periocular anesthesia.
    Ophthalmology, 2012, Volume: 119, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Blepharoplasty; Buffers; Doub

2012
Double-blind, bilateral pain comparison with simultaneous injection of 2% lidocaine versus buffered 2% lidocaine for periocular anesthesia.
    Ophthalmology, 2012, Volume: 119, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Blepharoplasty; Buffers; Doub

2012
Comparison of metal and flexible sub-Tenon cannulas.
    Journal of cataract and refractive surgery, 2012, Volume: 38, Issue:8

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Catheters; Double-Blind M

2012
Prospective, double-masked, randomized trial comparing lidocaine gel to tetracaine drops in femtosecond laser-assisted LASIK.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2012, Volume: 28, Issue:10

    Topics: Anesthetics, Local; Corneal Stroma; Double-Blind Method; Eye Pain; Gels; Humans; Intraoperative Comp

2012
Ocular pain after intravitreal injection.
    Current eye research, 2013, Volume: 38, Issue:2

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Angiogenesis Inhibitors; Anti-Bacterial Agents; Anti-In

2013

Other Studies

11 other studies available for lidocaine and Eye Pain

ArticleYear
Immediate postoperative topical lidocaine gel for the treatment of eye pain following corneal abrasion in descemet membrane endothelial keratoplasty (DMEK) under general anaesthesia: a pilot retrospective analysis.
    BMC anesthesiology, 2023, 09-09, Volume: 23, Issue:1

    Topics: Anesthesia, General; Corneal Injuries; Corneal Transplantation; Descemet Membrane; Eye Pain; Humans;

2023
A Comparison of Retrobulbar Versus Topical Anesthesia in Trabeculectomy and Aqueous Shunt Surgery.
    Journal of glaucoma, 2018, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cohort Studies; Eye

2018
Deep topical anesthesia with ropivacaine-soaked sponge for phacoemulsification.
    International ophthalmology, 2019, Volume: 39, Issue:12

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Eye Pain; Female; Humans; Intraocular Pressure;

2019
Evaluation of pain during intravitreal Ozurdex injections vs. intravitreal bevacizumab injections.
    Eye (London, England), 2014, Volume: 28, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, Monoclonal,

2014
Pain management with retrobulbar alcohol injection in absolute glaucoma.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:6

    Topics: Adult; Aged; Anesthetics, Local; Cohort Studies; Ethanol; Eye Pain; Female; Glaucoma; Humans; Inject

2015
Retrobulbar hemorrhage and prasugrel.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2016, Volume: 51, Issue:6

    Topics: Anesthetics, Local; Blindness; Diabetic Retinopathy; Eye Pain; Female; Humans; Laser Coagulation; Li

2016
Comparative assessment of the effectiveness of anaesthesia for intravitreal bevacizumab injection.
    Clinical & experimental ophthalmology, 2011, Volume: 39, Issue:2

    Topics: Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, Monoc

2011
Local anaesthesia for trans-scleral cyclodiode laser procedures: surgeon and patient satisfaction with sub-Tenon's and peribulbar anaesthesia.
    Clinical & experimental ophthalmology, 2011, Volume: 39, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Ciliary Body; Eye Pain; Humans; Laser Therapy; Lasers, Semico

2011
Pain management in blind, painful eyes: clinical experience with retrobulbar alcohol injection in 4 cases.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2011, Volume: 23, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Blindness; Ethanol; Eye Pain; Female; Glaucoma, Neovasc

2011
The sources of pain during phacoemulsification using topical anesthesia.
    Eye (London, England), 2012, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Eye Pain; Female;

2012
Randomized double-masked controlled trial comparing pain scores with and without the use of supplementary 2% lidocaine gel in LASIK.
    American journal of ophthalmology, 2012, Volume: 154, Issue:2

    Topics: Anesthetics, Local; Eye Pain; Female; Humans; Keratomileusis, Laser In Situ; Lasers, Excimer; Lidoca

2012