lidocaine has been researched along with Eye Diseases in 25 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Eye Diseases: Diseases affecting the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical lidocaine (LDC) treatment using a gel or patch preparation is effective in the treatment of postherpetic neuralgia (PHN), but neither is suited for the eye in patients with ophthalmic PHN." | 9.14 | Lidocaine eye drops attenuate pain associated with ophthalmic postherpetic neuralgia. ( Kanai, A; Niki, Y; Okamoto, H; Okamoto, T; Suzuki, K, 2010) |
| "Topical lidocaine (LDC) treatment using a gel or patch preparation is effective in the treatment of postherpetic neuralgia (PHN), but neither is suited for the eye in patients with ophthalmic PHN." | 5.14 | Lidocaine eye drops attenuate pain associated with ophthalmic postherpetic neuralgia. ( Kanai, A; Niki, Y; Okamoto, H; Okamoto, T; Suzuki, K, 2010) |
| "A 45-year-old man with an internal carotid artery occlusion, cerebral hemispheric infarction, and an ipsilateral central retinal artery occlusion developed anterior segment necrosis after retrobulbar injection of lidocaine hydrochloride (Xylocaine) for treatment of an occlusion of the central retinal artery." | 3.66 | Anterior segment necrosis following treatment of central retinal artery occlusion: a clinicopathologic case report. ( Marcus, DF; Reeser, FH; Weidaw, CD, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (56.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scherrer, NM | 1 |
| Hopster, K | 1 |
| Kanai, A | 1 |
| Okamoto, T | 1 |
| Suzuki, K | 1 |
| Niki, Y | 1 |
| Okamoto, H | 1 |
| GUNDZIK, JD | 1 |
| MAYER, JH | 1 |
| ASAYAMA, R | 1 |
| SAKAUE, E | 1 |
| AKUTAGAWA, T | 1 |
| KUROKAWA, K | 1 |
| RODGER, FC | 1 |
| Theocharis, IP | 1 |
| Alexandridou, A | 1 |
| Tomic, Z | 1 |
| Greenberger, MH | 1 |
| Chin, GN | 1 |
| Almquist, HT | 1 |
| Davis, DB | 1 |
| Mandel, MR | 1 |
| van den Berg, AA | 1 |
| Honjol, NM | 1 |
| Parmar, N | 1 |
| Saini, JS | 1 |
| Roysarkar, TK | 1 |
| Grewal, SP | 1 |
| Sharma, A | 1 |
| Chevaleraud, E | 1 |
| Leroy, L | 1 |
| Lebuisson, DA | 1 |
| Coster, DJ | 1 |
| Phillips, GD | 1 |
| Laka, V | 1 |
| Demirok, A | 1 |
| Simşek, S | 1 |
| Cinal, A | 1 |
| Yaşar, T | 1 |
| Kwok, AK | 1 |
| Young, AL | 1 |
| Lam, DS | 1 |
| Sharma, T | 1 |
| Gopal, L | 1 |
| Shanmugam, MP | 1 |
| Bhende, P | 1 |
| George, J | 1 |
| Samanta, TK | 1 |
| Mukesh, BN | 1 |
| Weidaw, CD | 1 |
| Marcus, DF | 1 |
| Reeser, FH | 1 |
| Schlegel, HJ | 1 |
| Gupta, PP | 1 |
| Asthana, OP | 1 |
| Dhawan, BN | 1 |
| Goel, R | 1 |
| Shukla, KN | 1 |
| Smith, RB | 1 |
| Everett, WG | 1 |
| Barza, M | 1 |
| Ernst, C | 1 |
| Baum, J | 1 |
| Weinstein, L | 1 |
| Weekers, JF | 1 |
| Judit, BS | 1 |
| Doden, W | 1 |
| Makabe, R | 1 |
| Ellis, GS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pain During Pars Plana Vitrectomy Comparing Peribulbar Anesthesia Versus Sub-tenon Injection Plus Topical Jelly Anesthesia[NCT03902925] | Phase 1/Phase 2 | 56 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| A Randomized Trial of Buffered vs Nonbuffered Lidocaine With Epinephrine for Cervical Loop Excision[NCT01405768] | Phase 2 | 56 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine Arm | 25 |
| Buffered Lidocaine | 19 |
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of the procedure
| Intervention | units on a scale (Median) |
|---|---|
| Lidocaine Arm | 26 |
| Buffered Lidocaine | 18 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 19 | 19 | 18 |
| Lidocaine Arm | 25 | 27 | 19 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Median) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 18 | 13 | 14 |
| Lidocaine Arm | 26 | 25 | 19 |
1 review available for lidocaine and Eye Diseases
| Article | Year |
|---|---|
Physiology and pharmacology of local anesthetic agents.
Topics: Administration, Topical; Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Ce | 1973 |
6 trials available for lidocaine and Eye Diseases
| Article | Year |
|---|---|
Neuromuscular blockade with atracurium for ophthalmic surgery in horses-Effects on surgical and anesthetic characteristics and recovery quality.
Topics: Animals; Atracurium; Eye Diseases; Horse Diseases; Horses; Lidocaine; Neuromuscular Blockade; Neurom | 2021 |
Lidocaine eye drops attenuate pain associated with ophthalmic postherpetic neuralgia.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Eye Diseases; | 2010 |
Bupivacaine and lidocaine retrobulbar anesthesia. A double-blind clinical study.
Topics: Adult; Aged; Anesthesia, Local; Bupivacaine; Clinical Trials as Topic; Double-Blind Method; Epinephr | 1983 |
Peribulbar anesthesia: one versus two injections.
Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Drug Combinations; Eye Diseases; Eye Movements; | 1997 |
Comparison of pH-adjusted bupivacaine with a mixture of non-pH-adjusted bupivacaine and lignocaine in primary vitreoretinal surgery.
Topics: Alkalies; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Double-Blind Me | 2002 |
Clinical evaluation of centbucridine in ophthalmic surgery.
Topics: Adolescent; Adult; Aged; Aminoacridines; Anesthetics, Local; Double-Blind Method; Eye Diseases; Fema | 1985 |
18 other studies available for lidocaine and Eye Diseases
| Article | Year |
|---|---|
THE USE OF DIAMOX AND RETROBULBAR INJECTION TO PREVENT VITREOUS LOSS.
Topics: Acetazolamide; Cataract Extraction; Eye Diseases; Geriatrics; Humans; Injections; Intraocular Pressu | 1963 |
[CLINICAL EXPERIENCE WITH THE USE OF A NEW LOCAL ANESTHETIC, CITANEST].
Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Biomedical Research; Epinephrine; Eye Diseases; | 1964 |
REPOSITORY CORTICOTHERAPY IN OPHTHALMIC THEORY AND PRACTICE.
Topics: Drug Therapy; Endophthalmitis; Eye Diseases; Humans; Injections; Keratitis; Lidocaine; Methylprednis | 1965 |
A two-year prospective study comparing lidocaine 2% jelly versus peribulbar anaesthesia for 25G and 23G sutureless vitrectomy.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cons | 2007 |
Central retinal artery closure in Wegener's granulomatosis.
Topics: Eye Diseases; Fundus Oculi; Granulomatosis with Polyangiitis; Heparin; Humans; Lidocaine; Male; Midd | 1967 |
Efficacy and complication rate of 16,224 consecutive peribulbar blocks. A prospective multicenter study.
Topics: Aged; Anesthesia, Local; Bupivacaine; Eye Diseases; Eye Movements; Female; Humans; Hyaluronoglucosam | 1994 |
ENT and eye anaesthesia: to spray or not to spray--a rationalisation.
Topics: Administration, Topical; Adult; Anesthesia, General; Eye Diseases; Female; Humans; Lidocaine; Male; | 1993 |
Efficacy and timed sequence analyses of modified single-injection peribulbar anesthesia.
Topics: Anesthesia, Local; Bupivacaine; Eye Diseases; Eyelids; Humans; Lidocaine; Massage; Muscles; Oculomot | 1993 |
[EMLA cream: prudent use and warnings].
Topics: Anesthesia, Local; Anesthetics, Local; Eye; Eye Diseases; Humans; Lidocaine; Ointments; Prilocaine | 1995 |
Day ophthalmic surgery: aspects of perioperative care.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Day Care, Medical; Eye Diseases; Female; Humans; | 1996 |
Efficacy of lignocaine gel for outpatient laser treatment in inflamed eyes.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Child; Eye | 2001 |
Anterior segment necrosis following treatment of central retinal artery occlusion: a clinicopathologic case report.
Topics: Arterial Occlusive Diseases; Epinephrine; Eye; Eye Diseases; Humans; Ischemia; Lidocaine; Male; Midd | 1978 |
[Long-acting local anesthetics - an enrichment in ophthalmosurgery? (author's transl)].
Topics: Anesthetics, Local; Body Temperature; Bupivacaine; Delayed-Action Preparations; Eye Diseases; Humans | 1977 |
Effect of lidocaine on the antibacterial activity of seven antibiotics.
Topics: Anti-Bacterial Agents; Carbenicillin; Cephaloridine; Cephalothin; Drug Interactions; Eye Diseases; G | 1974 |
[Experimental studies of the genesis of corneal lesions caused by anesthetics].
Topics: Aminobenzoates; Anesthetics; Animals; Cornea; Eye Diseases; Lidocaine; Rabbits | 1974 |
[Iatrogenic lesion in ophthalmologic anesthesia].
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics; Anesthetics, Local; Atropine; Blin | 1972 |
[Transitory visual loss after retrobulbar anesthesia].
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Eye Diseases; Humans; Injections; Lidocaine; Middle Aged | 1969 |
Akinesia of the facial nerve: a laboratory investigation of the surgical anatomy.
Topics: Academic Dissertations as Topic; Anesthesia, Conduction; Cadaver; Ear, Middle; Eye Diseases; Facial | 1968 |