Page last updated: 2024-10-28

lidocaine and Extravascular Hemolysis

lidocaine has been researched along with Extravascular Hemolysis in 24 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"In the present study we examined the utility, sensitivity and specificity of the cadmium- and heat-induced hemolysis, investigating the effects of diclofenac, salicylate and lidocaine, carticaine and procaine on the rabbit erythrocyte membrane."7.66Effects of diclofenac-sodium and salicylate, carticaine, lidocaine and procaine in the cadmium- and heat-induced hemolysis. ( Weischer, CH, 1980)
"Lidocaine is a widely used local anesthetic agent."5.31Lidocaine inhibits potassium efflux and hemolysis in erythrocytes during oxidative stress in vitro. ( Freysz, M; Lahet, JJ; Lenfant, F; Rochette, L; Vergely, C; Volot, F, 2000)
"Lidocaine did not inhibit the binding of the lysophospholipid to the red cell membrane, but inhibited hemolysis in a manner similar to cholesterol."5.27The effect of lidocaine on lysophosphatidylcholine-induced cardiac arrhythmias and cellular disturbances. ( Choy, PC; Lederman, CL; Man, RY; Neufeld, KJ, 1985)
"In the present study we examined the utility, sensitivity and specificity of the cadmium- and heat-induced hemolysis, investigating the effects of diclofenac, salicylate and lidocaine, carticaine and procaine on the rabbit erythrocyte membrane."3.66Effects of diclofenac-sodium and salicylate, carticaine, lidocaine and procaine in the cadmium- and heat-induced hemolysis. ( Weischer, CH, 1980)
"A 45-year-old woman with rheumatoid arthritis developed anaphylaxis 6 min after receiving a subcutaneous injection of lidocaine, followed by an intra-articular injection of lidocaine mixed with methprednisolone acetate."3.65Acute anaphylaxis associated with serum complement depletion. ( Ruddy, S; Schur, PH; Tannenbaum, H, 1975)
"Lidocaine has been shown to protect erythrocytes from oxidative stress by a possible membrane effect."1.32The protective effects of lidocaine on human erythrocytes stored for seven days at 04 degrees C. ( Chaillot, B; Freysz, M; Lahet, JJ; Lenfant, F, 2004)
"Lidocaine is a widely used local anesthetic agent."1.31Lidocaine inhibits potassium efflux and hemolysis in erythrocytes during oxidative stress in vitro. ( Freysz, M; Lahet, JJ; Lenfant, F; Rochette, L; Vergely, C; Volot, F, 2000)
"Only aprindine caused an increase in LDH leakage above 2 X 10(-4) M."1.27[Effects of antiarrhythmic drugs on rat erythrocytes, isolated hepatocytes and dipalmitoyl phosphatidyl choline (DPPC)-liposomes]. ( Kasahara, T; Kawashima, I; Manabe, A; Nakayama, S; Sakamoto, K; Shirasaki, K, 1985)
"Lidocaine did not inhibit the binding of the lysophospholipid to the red cell membrane, but inhibited hemolysis in a manner similar to cholesterol."1.27The effect of lidocaine on lysophosphatidylcholine-induced cardiac arrhythmias and cellular disturbances. ( Choy, PC; Lederman, CL; Man, RY; Neufeld, KJ, 1985)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199015 (62.50)18.7374
1990's0 (0.00)18.2507
2000's6 (25.00)29.6817
2010's0 (0.00)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Ballesteros, A1
Trullas, C1
Jourdan, E1
Gili, JM1
Tian, C1
Wang, Z1
Huang, L1
Liu, Y1
Wu, K1
Li, Z1
Han, B1
Jiao, D1
Han, X1
Zhao, Y1
Khajavirad, N1
Daftari, G1
Jelodar, MR1
HOENIG, J1
MALM, L2
PERSSON, H2
BRAENDSTROEM, A1
ANDERSEN, NB2
GRAVENSTEIN, JS1
Lenfant, F3
Lahet, JJ3
Courderot-Masuyer, C1
Freysz, M3
Rochette, L2
Chaillot, B1
Katsuki, H1
Tateyama, S1
Hidaka, N1
Yano, T1
Ibusuki, S1
Takasaki, M1
Parsi, K1
Exner, T1
Connor, DE1
Herbert, A1
Ma, DDF1
Joseph, JE1
Weischer, CH1
Vergely, C1
Volot, F1
García, DA1
Quiroga, S1
Perillo, MA1
Tannenbaum, H1
Ruddy, S1
Schur, PH1
Godin, DV1
Au, T1
Garnett, ME1
Beatty, RC1
Martin, KJ1
Otto, HH1
Krastel, V1
Reuter, W1
Manabe, A1
Shirasaki, K1
Kawashima, I1
Nakayama, S1
Kasahara, T1
Sakamoto, K1
Neufeld, KJ1
Lederman, CL1
Choy, PC1
Man, RY1
Sörensen, SE1
Sheetz, MP1
Singer, SJ1
Langslet, A1
Johansen, WG1
Ryg, M1
Skomedal, T1
Oye, I1
Daniel, EE1
Wolowyk, M1

Other Studies

24 other studies available for lidocaine and Extravascular Hemolysis

ArticleYear
Inhibition of Nematocyst Discharge from
    Marine drugs, 2022, Sep-08, Volume: 20, Issue:9

    Topics: Ammonia; Animals; Bites and Stings; Butylene Glycols; Cnidaria; Cnidarian Venoms; Ethanol; Hemolysis

2022
One-step fabrication of lidocaine/CalliSpheres
    Journal of translational medicine, 2022, 10-11, Volume: 20, Issue:1

    Topics: Carrageenan; Embolization, Therapeutic; Hemolysis; Humans; Inflammation; Interleukin-10; Interleukin

2022
Hemolysis and acquired methemoglobinemia associated with lidocaine and benzocaine topical application: a case report.
    Journal of medical case reports, 2023, Apr-20, Volume: 17, Issue:1

    Topics: Adult; Anesthetics, Local; Benzocaine; Hemolysis; Humans; Lidocaine; Male; Methemoglobinemia; Methyl

2023
ISOTONIA IN XYLOCAINE SOLUTIONS.
    Acta pharmaceutica Suecica, 1964, Volume: 1

    Topics: Chemistry, Pharmaceutical; Glucose; Hematocrit; Hemolysis; Hydrogen-Ion Concentration; Isotonic Solu

1964
PHYSICO-CHEMICAL ASPECTS OF THE HAEMOLYTIC EFFECT OF LOCAL ANAESTHETICS.
    Acta pharmaceutica Suecica, 1964, Volume: 1

    Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Hemolysis; Hydrogen-Ion Concentration; Ions; Lid

1964
EFFECTS OF LOCAL ANESTHETICS ON SODIUM AND POTASSIUM IN HUMAN RED CELLS.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 147

    Topics: Anesthetics, Local; Cocaine; Computers, Analog; Dibucaine; Electronic Data Processing; Erythrocytes;

1965
Lidocaine has better antioxidant potential than ropivacaine and bupivacaine: in vitro comparison in a model of human erythrocytes submitted to an oxidative stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2004, Volume: 58, Issue:4

    Topics: Amides; Anesthetics, Local; Antioxidants; Biological Transport; Bupivacaine; Erythrocytes; Free Radi

2004
The protective effects of lidocaine on human erythrocytes stored for seven days at 04 degrees C.
    Cellular & molecular biology letters, 2004, Volume: 9, Issue:2

    Topics: Blood Preservation; Cold Temperature; Cryopreservation; Cryoprotective Agents; Erythrocytes; Hemolys

2004
[Glucose attenuating local anesthetic-induced hemolysis].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:9

    Topics: Anesthetics, Local; Dibucaine; Dose-Response Relationship, Drug; Erythrocyte Membrane; Glucose; Hemo

2004
The lytic effects of detergent sclerosants on erythrocytes, platelets, endothelial cells and microparticles are attenuated by albumin and other plasma components in vitro.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2008, Volume: 36, Issue:2

    Topics: Blood Platelets; Cell Line; Cytoprotection; Densitometry; Dose-Response Relationship, Drug; Endothel

2008
Effects of diclofenac-sodium and salicylate, carticaine, lidocaine and procaine in the cadmium- and heat-induced hemolysis.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:11

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Cadmium; Carticaine; Diclofenac; Dose-Respons

1980
Lidocaine inhibits potassium efflux and hemolysis in erythrocytes during oxidative stress in vitro.
    General pharmacology, 2000, Volume: 34, Issue:3

    Topics: Amidines; Anesthetics, Local; Antioxidants; Biological Transport; Electron Spin Resonance Spectrosco

2000
Flunitrazepam partitioning into natural membranes increases surface curvature and alters cellular morphology.
    Chemico-biological interactions, 2000, Dec-15, Volume: 129, Issue:3

    Topics: Cell Size; Dimethyl Sulfoxide; Erythrocyte Membrane; Erythrocytes; Flunitrazepam; Hemolysis; Humans;

2000
Acute anaphylaxis associated with serum complement depletion.
    The Journal of allergy and clinical immunology, 1975, Volume: 56, Issue:3

    Topics: Anaphylaxis; Animals; Antibodies; Antigen-Antibody Complex; Arthritis, Rheumatoid; Complement System

1975
Membrane perturbational effects of antiarrhythmic drugs.
    Journal of molecular and cellular cardiology, 1979, Volume: 11, Issue:3

    Topics: Anti-Arrhythmia Agents; Bretylium Tosylate; Dithionitrobenzoic Acid; Dose-Response Relationship, Dru

1979
Antagonistic effects of two anaesthetics of hypotonic haemolysis [proceedings].
    British journal of pharmacology, 1978, Volume: 62, Issue:3

    Topics: Anesthetics; Benzyl Alcohols; Benzyl Compounds; Hemolysis; In Vitro Techniques; Lidocaine; Osmotic F

1978
[Medicinal reduction of mechanical hemolysis].
    Zeitschrift fur experimentelle Chirurgie, 1977, Volume: 10, Issue:1

    Topics: Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Lidocaine

1977
[Effects of antiarrhythmic drugs on rat erythrocytes, isolated hepatocytes and dipalmitoyl phosphatidyl choline (DPPC)-liposomes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Cell Membrane; Erythrocyte Membrane; Hemolysis; In Vitro

1985
The effect of lidocaine on lysophosphatidylcholine-induced cardiac arrhythmias and cellular disturbances.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:7

    Topics: Albumins; Animals; Arrhythmias, Cardiac; Cell Membrane; Cholesterol; Electrocardiography; Erythrocyt

1985
Local toxic effects of anaesthetics and contrast media in urethrography.
    Acta radiologica: diagnosis, 1972, Volume: 12, Issue:2

    Topics: Anesthetics, Local; Animals; Blood Flow Velocity; Capillary Fragility; Capillary Permeability; Cells

1972
Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:11

    Topics: Binding Sites; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Erythrocytes; Hemolysis; H

1974
Effects of dibenzepine and imipramine on the isolated rat heart.
    European journal of pharmacology, 1971, Volume: 14, Issue:4

    Topics: Animals; Biological Transport; Cold Temperature; Coronary Vessels; Depression, Chemical; Dibenzazepi

1971
The effect of local anesthetic and pH on sodium and potassium flux in human red cells.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 163, Issue:2

    Topics: Biological Transport, Active; Cell Membrane Permeability; Cocaine; Depression, Chemical; Dibucaine;

1968
The contractile response of the uterus to cocaine.
    Canadian journal of physiology and pharmacology, 1966, Volume: 44, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Calcium; Catecholamines; Cocaine; Dibucaine; Diethylstilbestrol; E

1966